HTTP 200 OK
Allow: GET, POST, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"recordsFiltered": 48186,
"recordsTotal": 48186,
"next": "http://fdaaa.trialstracker.net/api/trials/?format=api&length=300&start=46500",
"previous": "http://fdaaa.trialstracker.net/api/trials/?format=api&length=300&start=45900",
"results": [
{
"registry_id": "NCT07124117",
"publication_url": "https://clinicaltrials.gov/study/NCT07124117",
"title": "A Phase 1/2, Open-Label, Dose-Escalation and Cohort-Expansion Study Evaluating the Safety, Pharmacokinetics, and Therapeutic Activity of OBI-902 in Participants With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2025-08-04",
"completion_date": "2029-02-08",
"has_results": false,
"results_due": false,
"sponsor_name": "OBI Pharma, Inc",
"sponsor_slug": "obi-pharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06745323",
"publication_url": "https://clinicaltrials.gov/study/NCT06745323",
"title": "A Phase 2, Open-label, Randomized, Multicenter Study of Tarlatamab Dosing Regimens in Subjects With Small Cell Lung Cancer (SCLC) (DeLLphi-309)",
"has_exemption": false,
"start_date": "2025-02-26",
"completion_date": "2029-02-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Amgen",
"sponsor_slug": "amgen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07416565",
"publication_url": "https://clinicaltrials.gov/study/NCT07416565",
"title": "A Prospective, Single-center Study of the Utility of the ATEC IOA Imaging Platform Tool in Intraoperative Imaging for Patients Undergoing Adult Spinal Deformity Surgery.",
"has_exemption": false,
"start_date": "2026-02-09",
"completion_date": "2029-02-09",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04923893",
"publication_url": "https://clinicaltrials.gov/study/NCT04923893",
"title": "A Phase 3 Randomized Study Comparing Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Ciltacabtagene Autoleucel, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against BCMA Versus Bortezomib, Lenalidomide, and Dexamethasone (VRd) Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy",
"has_exemption": false,
"start_date": "2021-08-19",
"completion_date": "2029-02-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07155226",
"publication_url": "https://clinicaltrials.gov/study/NCT07155226",
"title": "A Modular Phase I/II, Open-label, Multi-Centre Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression",
"has_exemption": false,
"start_date": "2026-01-09",
"completion_date": "2029-02-15",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06205602",
"publication_url": "https://clinicaltrials.gov/study/NCT06205602",
"title": "A Randomized, Double-Blind, Placebo-Controlled Study of the Combination of Two Long-Acting Broadly Neutralizing Antibodies at ART Initiation in Adults Living With HIV-1 in Sub-Saharan Africa: The ACACIA Study",
"has_exemption": false,
"start_date": "2025-01-17",
"completion_date": "2029-02-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections",
"sponsor_slug": "advancing-clinical-therapeutics-globally-for-hivaids-and-other-infections",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06794541",
"publication_url": "https://clinicaltrials.gov/study/NCT06794541",
"title": "Multicenter, Open-label Trial to Evaluate the Safety and Tolerability of Intravenous Eravacycline in Pediatric Patients From 8 Years to Less Than 18 Years of Age With Complicated Intra-abdominal Infections (cIAI)",
"has_exemption": false,
"start_date": "2025-05-22",
"completion_date": "2029-02-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Tetraphase Pharmaceuticals, Inc.",
"sponsor_slug": "tetraphase-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05314023",
"publication_url": "https://clinicaltrials.gov/study/NCT05314023",
"title": "A Phase 3 Open-Label Immunogenicity and Safety Study of 2-Dose Regimens of V503, a 9-Valent Human Papillomavirus (HPV) Vaccine in Chinese Males 9 Through 14 Years Old and 3-Dose Regimen of V503 in Chinese Males 9 Through 19 Years Old",
"has_exemption": false,
"start_date": "2022-05-07",
"completion_date": "2029-02-19",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06345729",
"publication_url": "https://clinicaltrials.gov/study/NCT06345729",
"title": "A Phase 3, Randomized, Double-blind, Multicenter Study of MK-1084 in Combination With Pembrolizumab Compared With Pembrolizumab Plus Placebo as Firstline Treatment of Participants With KRAS G12C-Mutant, Locally Advanced or Metastatic NSCLC With PD-L1 TPS ≥50% (KANDLELIT-004)",
"has_exemption": false,
"start_date": "2024-05-24",
"completion_date": "2029-02-19",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06290193",
"publication_url": "https://clinicaltrials.gov/study/NCT06290193",
"title": "A Prospective Randomized Trial of Acute Normovolemic Hemodilution (ANH) in Patients Undergoing Cytoreductive Surgery for Ovarian Cancer",
"has_exemption": false,
"start_date": "2024-02-23",
"completion_date": "2029-02-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06996782",
"publication_url": "https://clinicaltrials.gov/study/NCT06996782",
"title": "A Phase Ib/II Open-Label, Multicentre Platform Study Evaluating Novel Combinations in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2025-11-24",
"completion_date": "2029-02-23",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05744921",
"publication_url": "https://clinicaltrials.gov/study/NCT05744921",
"title": "An Open-Label Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of Pozelimab and Cemdisiran Combination Therapy in Patients With Paroxysmal Nocturnal Hemoglobinuria",
"has_exemption": false,
"start_date": "2023-03-07",
"completion_date": "2029-02-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05115110",
"publication_url": "https://clinicaltrials.gov/study/NCT05115110",
"title": "A Two-Part, Seamless, Multi-Center, Randomized, Placebo-Controlled, Double-Blind Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of RO7204239 in Combination With Risdiplam (RO7034067) in Patients With Spinal Muscular Atrophy",
"has_exemption": false,
"start_date": "2022-06-02",
"completion_date": "2029-02-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06797999",
"publication_url": "https://clinicaltrials.gov/study/NCT06797999",
"title": "A First-in-human, Phase 1/2, Multicenter, Open-label, Dose Escalation and Expansion Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of ADCE-D01, a Humanized Anti-human uPARAP Antibody Linked to a Topoisomerase I Inhibitor, in Patients With Metastatic and/or Unresectable Soft Tissue Sarcoma",
"has_exemption": false,
"start_date": "2025-06-05",
"completion_date": "2029-02-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Adcendo ApS",
"sponsor_slug": "adcendo-aps",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07222566",
"publication_url": "https://clinicaltrials.gov/study/NCT07222566",
"title": "AN INTERVENTIONAL PHASE 3, DOUBLE-BLIND, RANDOMIZED STUDY TO EVALUATE EFFICACY AND SAFETY OF PF-08634404 IN COMBINATION WITH CHEMOTHERAPY VERSUS PEMBROLIZUMAB IN COMBINATION WITH CHEMOTHERAPY IN ADULT PARTICIPANTS WITH LOCALLY ADVANCED OR METASTATIC NON-SMALL CELL LUNG CANCER",
"has_exemption": false,
"start_date": "2026-01-06",
"completion_date": "2029-02-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02577120",
"publication_url": "https://clinicaltrials.gov/study/NCT02577120",
"title": "Wound Healing Endpoint and Recurrence",
"has_exemption": false,
"start_date": "2019-01-08",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Sashwati Roy",
"sponsor_slug": "sashwati-roy",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03495427",
"publication_url": "https://clinicaltrials.gov/study/NCT03495427",
"title": "The Utility of PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men With High GC Decipher® Test Scores: A Sub-aim of the VANDAAM Study (MCC #18523)",
"has_exemption": false,
"start_date": "2019-12-18",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04416984",
"publication_url": "https://clinicaltrials.gov/study/NCT04416984",
"title": "A Single-Arm, Open-Label, Phase 1/2 Study Evaluating the Safety, Efficacy, and Cellular Kinetics/Pharmacodynamics of ALLO-501A, an Anti-CD19 Allogeneic CAR T Cell Therapy, and ALLO-647, an Anti-CD52 Monoclonal Antibody, in Subjects With Relapsed/Refractory Large B-Cell Lymphoma (LBCL)",
"has_exemption": false,
"start_date": "2020-05-21",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Allogene Therapeutics",
"sponsor_slug": "allogene-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04469530",
"publication_url": "https://clinicaltrials.gov/study/NCT04469530",
"title": "A Maintenance Protocol of Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors",
"has_exemption": false,
"start_date": "2020-09-16",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04499248",
"publication_url": "https://clinicaltrials.gov/study/NCT04499248",
"title": "A Phase 1/2 Study to Evaluate the Safety and Efficacy of AGN-193408 SR in Participants With Open-Angle Glaucoma or Ocular Hypertension",
"has_exemption": false,
"start_date": "2020-11-16",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05013333",
"publication_url": "https://clinicaltrials.gov/study/NCT05013333",
"title": "Post-Approval Study for AED 3 With Uni-padz",
"has_exemption": false,
"start_date": "2021-03-30",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Zoll Medical Corporation",
"sponsor_slug": "zoll-medical-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04783181",
"publication_url": "https://clinicaltrials.gov/study/NCT04783181",
"title": "A Phase 1/2, First-in-Human, Open-Label, Dose-Escalation Study of the Safety and Efficacy of Gene Therapy for Congenital Adrenal Hyperplasia Through Administration of an Adeno-Associated Virus (AAV) Serotype 5-Based Recombinant Vector Encoding the Human CYP21A2 Gene",
"has_exemption": false,
"start_date": "2021-07-01",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Adrenas Therapeutics Inc",
"sponsor_slug": "adrenas-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05135091",
"publication_url": "https://clinicaltrials.gov/study/NCT05135091",
"title": "A Study of Inhibitory Interneurons (NRTX-1001) in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (MTLE)",
"has_exemption": false,
"start_date": "2022-06-16",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Neurona Therapeutics",
"sponsor_slug": "neurona-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05541822",
"publication_url": "https://clinicaltrials.gov/study/NCT05541822",
"title": "A Phase 2 Multicenter, Open-Label, Parallel Cohort Expansion Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetic Profile of ABN401 in Patients With Advanced Solid Tumors Harboring c-Mesenchymal-epithelial Transition Factor (c-MET) Dysregulation",
"has_exemption": false,
"start_date": "2023-01-17",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Abion Inc",
"sponsor_slug": "abion-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05195905",
"publication_url": "https://clinicaltrials.gov/study/NCT05195905",
"title": "Evaluation of Spinal Cord Ischemia and Mortality and Morbidity After Endovascular Repair of Pararenal and Thoracoabdominal Aortic Aneurysm Using Surgeon-Modified Endografts",
"has_exemption": false,
"start_date": "2023-06-06",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Konstantinos Dean Arnaoutakis, MD",
"sponsor_slug": "konstantinos-dean-arnaoutakis-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05930561",
"publication_url": "https://clinicaltrials.gov/study/NCT05930561",
"title": "A Phase 2 Randomized, Active-Controlled, Double-masked Trial of Intravitreal 4D-150 Gene Therapy in Adults With Diabetic Macular Edema (SPECTRA)",
"has_exemption": false,
"start_date": "2023-08-09",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "4D Molecular Therapeutics",
"sponsor_slug": "4d-molecular-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06118905",
"publication_url": "https://clinicaltrials.gov/study/NCT06118905",
"title": "Preserving Geriatric Muscle With an Osteoporosis Medication",
"has_exemption": false,
"start_date": "2024-02-08",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Susan L. Greenspan",
"sponsor_slug": "susan-l-greenspan",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06511453",
"publication_url": "https://clinicaltrials.gov/study/NCT06511453",
"title": "Remote Self-Administered Acupressure for Pain Management in Patients With Sickle Cell Disease",
"has_exemption": false,
"start_date": "2024-03-07",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06318169",
"publication_url": "https://clinicaltrials.gov/study/NCT06318169",
"title": "A Phase 3 Study to Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis",
"has_exemption": false,
"start_date": "2024-03-13",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "89bio, Inc.",
"sponsor_slug": "89bio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06295744",
"publication_url": "https://clinicaltrials.gov/study/NCT06295744",
"title": "Patient-Reported Outcomes and Cosmesis Following Five Fraction Whole Breast Irradiation With Simultaneous Integrated Boost",
"has_exemption": false,
"start_date": "2024-04-17",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06383390",
"publication_url": "https://clinicaltrials.gov/study/NCT06383390",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Event-Driven Study to Investigate the Effect of Retatrutide on the Incidence of Major Adverse Cardiovascular Events and Major Adverse Kidney Events in Participants With Body Mass Index ≥27 kg/m2 and Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease",
"has_exemption": false,
"start_date": "2024-04-30",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06177964",
"publication_url": "https://clinicaltrials.gov/study/NCT06177964",
"title": "Randomized Phase 2 Clinical Trial of Repeated Intratumoral and Cervical Perilymphatic Lerapolturev Injections Versus Lomustine in Recurrent Glioblastoma (GBM)",
"has_exemption": false,
"start_date": "2024-07-15",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Darell Bigner",
"sponsor_slug": "darell-bigner",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06415344",
"publication_url": "https://clinicaltrials.gov/study/NCT06415344",
"title": "A Long-term Extension Trial Investigating the Safety and Efficacy of GTX-102 in Patients With Angelman Syndrome",
"has_exemption": false,
"start_date": "2024-07-31",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Ultragenyx Pharmaceutical Inc",
"sponsor_slug": "ultragenyx-pharmaceutical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05665738",
"publication_url": "https://clinicaltrials.gov/study/NCT05665738",
"title": "Two-fraction High Dose Rate Brachytherapy as Monotherapy Delivered Three Hours Apart in Localized Prostate Cancer: A Pilot Study",
"has_exemption": false,
"start_date": "2024-09-11",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05870111",
"publication_url": "https://clinicaltrials.gov/study/NCT05870111",
"title": "Neurobehavioral and Immune Effects of Citicoline in Youth Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2024-10-01",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University of South Carolina",
"sponsor_slug": "medical-university-of-south-carolina",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06347796",
"publication_url": "https://clinicaltrials.gov/study/NCT06347796",
"title": "Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study",
"has_exemption": false,
"start_date": "2024-11-01",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Medical Branch, Galveston",
"sponsor_slug": "the-university-of-texas-medical-branch-galveston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05945329",
"publication_url": "https://clinicaltrials.gov/study/NCT05945329",
"title": "A Prospective, Randomized, Controlled, Multi-Center Study of GalaFLEX LITE™ Scaffold in Treatment of Capsular Contracture After Breast Implant Augmentation",
"has_exemption": false,
"start_date": "2024-12-12",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "C. R. Bard",
"sponsor_slug": "c-r-bard",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06712316",
"publication_url": "https://clinicaltrials.gov/study/NCT06712316",
"title": "A Phase II/III, Multisite, Randomized Master Protocol for a Global Trial of BNT327 in Combination With Chemotherapy and Other Investigational Agents in First-line Non-small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2025-01-07",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Biontech SE",
"sponsor_slug": "biontech-se",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06704152",
"publication_url": "https://clinicaltrials.gov/study/NCT06704152",
"title": "A Phase 1/2a Multicenter Ascending Dose Study to Evaluate the Safety of HA-1 Minor Histocompatibility Antigen-Reactive TCR-Modified T Cells (BSB-1001) in Patients Undergoing HLA-Matched Allogenic Hematopoietic Stem Cell Transplant for AML, ALL or MDS",
"has_exemption": false,
"start_date": "2025-02-04",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "BlueSphere Bio, Inc",
"sponsor_slug": "bluesphere-bio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06703125",
"publication_url": "https://clinicaltrials.gov/study/NCT06703125",
"title": "The Alama Project: Autism Outcomes and Neurobehavioral Markers in Young Children Born to Mothers With HIV in Kenya",
"has_exemption": false,
"start_date": "2025-02-11",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06777446",
"publication_url": "https://clinicaltrials.gov/study/NCT06777446",
"title": "Elective Adhesiolysis vs. a Wait-and-see Policy to Prevent Recurrences After Conservative Treatment of Adhesive Small Bowel Obstruction",
"has_exemption": false,
"start_date": "2025-02-28",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Radboud University Medical Center",
"sponsor_slug": "radboud-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06628453",
"publication_url": "https://clinicaltrials.gov/study/NCT06628453",
"title": "Continuous Glucose Monitoring for Management of Type 2 Diabetes in Pregnancy",
"has_exemption": false,
"start_date": "2025-04-08",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06777901",
"publication_url": "https://clinicaltrials.gov/study/NCT06777901",
"title": "Randomized Controlled Trial of the Auryon Atherectomy System Used in Combination With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone Treating Infrapopliteal Lesions in Subjects With Critical Limb Ischemia",
"has_exemption": false,
"start_date": "2025-04-21",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Angiodynamics, Inc.",
"sponsor_slug": "angiodynamics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06790966",
"publication_url": "https://clinicaltrials.gov/study/NCT06790966",
"title": "A Phase 3 Open-Label, Randomized Study of PDS0101 and Pembrolizumab vs Pembrolizumab Alone in First-Line Treatment of Unresectable Recurrent and/or Metastatic HPV16+ Head and Neck Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2025-05-30",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "PDS Biotechnology Corp.",
"sponsor_slug": "pds-biotechnology-corp",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06844214",
"publication_url": "https://clinicaltrials.gov/study/NCT06844214",
"title": "A Phase 1/Phase 2 Open-label Single Arm Study With Dose Escalation (Part A), and Dose Expansion (Part B) Parts to Evaluate the Safety, Tolerability, and Efficacy of SAR446268, an Adeno-associated Viral Vector-mediated Gene Therapy in Participants 10 to 50 Years Old With Non-congenital Myotonic Dystrophy Type 1",
"has_exemption": false,
"start_date": "2025-07-23",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07096193",
"publication_url": "https://clinicaltrials.gov/study/NCT07096193",
"title": "Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta",
"has_exemption": false,
"start_date": "2025-07-31",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Gilead Sciences",
"sponsor_slug": "gilead-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06624644",
"publication_url": "https://clinicaltrials.gov/study/NCT06624644",
"title": "A Multicenter, Open-Label, Randomized, Controlled Study to Assess the Antitumor Activity of LNS8801 With and Without Pembrolizumab in Patients With Treatment-Refractory, Unresectable Melanoma",
"has_exemption": false,
"start_date": "2025-08-06",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Linnaeus Therapeutics, Inc.",
"sponsor_slug": "linnaeus-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07053800",
"publication_url": "https://clinicaltrials.gov/study/NCT07053800",
"title": "A Single-Arm, Open-Label, Phase II Study to Determine the Safety and Efficacy of Obecabtagene Autoleucel (Obe-cel) in Participants With Severe, Refractory Systemic Lupus Erythematosus With Active Lupus Nephritis",
"has_exemption": false,
"start_date": "2025-09-30",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Autolus Limited",
"sponsor_slug": "autolus-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07095465",
"publication_url": "https://clinicaltrials.gov/study/NCT07095465",
"title": "52-Week, Phase 3, Open-Label Extension Study of ACP-204 in Adults With Lewy Body Dementia Psychosis (LBDP)",
"has_exemption": false,
"start_date": "2025-11-14",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "ACADIA Pharmaceuticals Inc.",
"sponsor_slug": "acadia-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07222488",
"publication_url": "https://clinicaltrials.gov/study/NCT07222488",
"title": "Phase 1/2 Study of Intravesical MK-3120 in BCG-Naïve or BCG-Exposed High-Risk Non-muscle Invasive Bladder Cancer",
"has_exemption": false,
"start_date": "2025-12-09",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06796062",
"publication_url": "https://clinicaltrials.gov/study/NCT06796062",
"title": "A Phase 2 Trial of Psilocybin as an Adjunctive Treatment for OUD Patients Who Continue to Use Illicit Opioids Despite Adherence to Methadone Treatment",
"has_exemption": false,
"start_date": "2025-12-17",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07185997",
"publication_url": "https://clinicaltrials.gov/study/NCT07185997",
"title": "A Global, Phase 3, Randomized, Multicenter, Open-Label Study to Evaluate the Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of Osimertinib or Afatinib as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic Non-Small-Cell Lung Cancer With Epidermal Growth Factor Receptor P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations (ALPACCA)",
"has_exemption": false,
"start_date": "2025-12-17",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "ArriVent BioPharma, Inc.",
"sponsor_slug": "arrivent-biopharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07130786",
"publication_url": "https://clinicaltrials.gov/study/NCT07130786",
"title": "A Phase II Randomized Open-Label Trial of Levetiracetam for Prevention of Seizures in Patients With Brain Metastases in Primary Motor Cortex",
"has_exemption": false,
"start_date": "2025-12-23",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Ayal A. Aizer, MD",
"sponsor_slug": "ayal-a-aizer-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06795074",
"publication_url": "https://clinicaltrials.gov/study/NCT06795074",
"title": "Risk of Recurrent Urethral Stricture After Treatment With Paclitaxel-Coated Dilatation Balloon (Optilume) Compared With Non-coated Dilatation Balloon - a Prospective Randomised Multicentre Study",
"has_exemption": false,
"start_date": "2026-01-16",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Vastra Gotaland Region",
"sponsor_slug": "vastra-gotaland-region",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07157514",
"publication_url": "https://clinicaltrials.gov/study/NCT07157514",
"title": "An Adaptive, Operationally Seamless Phase II / III Study of 131I-apamistamab-Led Allogeneic Hematopoietic Stem Cell Transplant in Patients With Relapsed or Refractory Acute Myeloid Leukemia With Active Disease",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Actinium Pharmaceuticals",
"sponsor_slug": "actinium-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07282821",
"publication_url": "https://clinicaltrials.gov/study/NCT07282821",
"title": "Bempedoic Acid Therapy for Polycystic Kidney Disease (BEAT-PKD) Randomized Clinical Trial",
"has_exemption": false,
"start_date": "2026-02-01",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Kenneth Hallows",
"sponsor_slug": "kenneth-hallows",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07400029",
"publication_url": "https://clinicaltrials.gov/study/NCT07400029",
"title": "A Phase II Trial of Obecabtagene Autoleucel Consolidation in Adult Patients With Acute Lymphoblastic Leukemia in First Complete Remission Without Measurable Residual Disease",
"has_exemption": false,
"start_date": "2026-02-03",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07335497",
"publication_url": "https://clinicaltrials.gov/study/NCT07335497",
"title": "A Phase 1/2, Multicenter, Open-label, Dose Escalation and Dose Expansion Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2026-02-17",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Crescent Biopharma, Inc.",
"sponsor_slug": "crescent-biopharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07285668",
"publication_url": "https://clinicaltrials.gov/study/NCT07285668",
"title": "Phase I Study of Prophylactic TCRαβ+ and CD19+ Depleted Donor Lymphocyte Infusion After Allogeneic Stem Cell Transplant in High-Risk Patients With Hematologic Malignancies",
"has_exemption": false,
"start_date": "2026-02-26",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06225050",
"publication_url": "https://clinicaltrials.gov/study/NCT06225050",
"title": "A Single-center Pilot Study Using TCRα/β and CD45RA Depleted Stem Cell Grafts From Haploidentical Donors for Hematopoietic Cell Transplantation in Adults(HAPLO2022)",
"has_exemption": false,
"start_date": "2026-02-28",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Miltenyi Biomedicine GmbH",
"sponsor_slug": "miltenyi-biomedicine-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07149363",
"publication_url": "https://clinicaltrials.gov/study/NCT07149363",
"title": "Adjuvant Chemotherapy and Immunotherapy for Completely Resected Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2026-02-28",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Alliance Foundation Trials, LLC.",
"sponsor_slug": "alliance-foundation-trials-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07450430",
"publication_url": "https://clinicaltrials.gov/study/NCT07450430",
"title": "Double-blind, Randomized, Placebo Controlled Study to Evaluate Optimal Timing of Ketamine Initiation",
"has_exemption": false,
"start_date": "2026-02-28",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Children’s Hospital",
"sponsor_slug": "boston-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07340658",
"publication_url": "https://clinicaltrials.gov/study/NCT07340658",
"title": "A Multicenter, Randomized, Double-Blind, Double-Dummy, Phase III Study to Evaluate the Efficacy and Safety of Letrozole SIE Compared to Femara® (Both in Combination With the CDK4/6 Inhibitor Palbociclib) in Postmenopausal Women With HR-Positive, HER2-Negative, Inoperable Locally Advanced or Metastatic Breast Cancer (SIE-3)",
"has_exemption": false,
"start_date": "2026-05-31",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Rovi Pharmaceuticals Laboratories",
"sponsor_slug": "rovi-pharmaceuticals-laboratories",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07042295",
"publication_url": "https://clinicaltrials.gov/study/NCT07042295",
"title": "A Randomized Phase II Study of Amivantamab (JNJ-61186372) and Hyaluronidase (rHuPH20) Versus Cetuximab in Immunocompromised Participants With Recurrent Inoperable or Metastatic Cutaneous Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2026-10-25",
"completion_date": "2029-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03949855",
"publication_url": "https://clinicaltrials.gov/study/NCT03949855",
"title": "Belimumab and Rituximab Compared to Rituximab Alone for the Treatment of Primary Membranous Nephropathy (ITN080AI)",
"has_exemption": false,
"start_date": "2020-03-06",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Allergy and Infectious Diseases (NIAID)",
"sponsor_slug": "national-institute-of-allergy-and-infectious-diseases-niaid",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05390892",
"publication_url": "https://clinicaltrials.gov/study/NCT05390892",
"title": "PRECIDENTD: PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes",
"has_exemption": false,
"start_date": "2022-09-26",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05432466",
"publication_url": "https://clinicaltrials.gov/study/NCT05432466",
"title": "A Phase 3 Randomized, Double-Blind, Decentralized Clinical Trial to Compare the Efficacy of Celiprolol to Placebo in the Treatment of Patients With COL3A1-Positive Vascular Ehlers-Danlos Syndrome",
"has_exemption": false,
"start_date": "2022-11-07",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Acer Therapeutics Inc.",
"sponsor_slug": "acer-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06072768",
"publication_url": "https://clinicaltrials.gov/study/NCT06072768",
"title": "Using SMART Design to Develop Dynamic Treatment Regimens for Glucocorticoid Tapering",
"has_exemption": false,
"start_date": "2023-03-09",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06014255",
"publication_url": "https://clinicaltrials.gov/study/NCT06014255",
"title": "A Phase 2 Randomized Trial of Neoadjuvant Enoblituzumab Versus Standard of Care in Men With High-Risk Localized Prostate Cancer: The Help Elucidate & Attack Longitudinally (HEAT) Prostate Cancer Randomized Study",
"has_exemption": false,
"start_date": "2024-02-16",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
"sponsor_slug": "sidney-kimmel-comprehensive-cancer-center-at-johns-hopkins",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05896228",
"publication_url": "https://clinicaltrials.gov/study/NCT05896228",
"title": "Phase 2, Single-Arm Study of Iberdomide, Daratumumab, Carfilzomib, and Dexamethasone (Iber-KDd) in Patients With Relapsed/Refractory Multiple Myeloma",
"has_exemption": false,
"start_date": "2024-02-20",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Benjamin T Diamond, MD",
"sponsor_slug": "benjamin-t-diamond-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06412198",
"publication_url": "https://clinicaltrials.gov/study/NCT06412198",
"title": "A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations",
"has_exemption": false,
"start_date": "2024-08-28",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06400121",
"publication_url": "https://clinicaltrials.gov/study/NCT06400121",
"title": "Phase 2, Randomized, Double-Blind, Placebo-Controlled, Single Intravenous Dose, Parallel Efficacy Study of Apimostinel With or Without Subsequent Automated Self-Association Training in Subjects With Major Depressive Disorder",
"has_exemption": false,
"start_date": "2024-10-28",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Rebecca Price",
"sponsor_slug": "rebecca-price",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06972056",
"publication_url": "https://clinicaltrials.gov/study/NCT06972056",
"title": "A Comparative Effectiveness Study of Oral Medications Used for Migraine Prevention: The APT Comparison Study",
"has_exemption": false,
"start_date": "2025-07-09",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07038824",
"publication_url": "https://clinicaltrials.gov/study/NCT07038824",
"title": "A 2-Part, Randomized, Double-Blind, Placebo-Controlled Study in Participants With Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping With an Initial Multiple Ascending Dose Part A to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ENTR-601-45, Followed by Part B to Evaluate the Safety and Efficacy of ENTR-601-45 (ELEVATE-45)",
"has_exemption": false,
"start_date": "2025-08-30",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Entrada Therapeutics, Inc.",
"sponsor_slug": "entrada-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07135895",
"publication_url": "https://clinicaltrials.gov/study/NCT07135895",
"title": "The Artix All-in-one Solution for Complete thrombEctomy With eNDovascular Approach",
"has_exemption": false,
"start_date": "2026-01-07",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Inari Medical",
"sponsor_slug": "inari-medical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06941415",
"publication_url": "https://clinicaltrials.gov/study/NCT06941415",
"title": "Bumetanide vs. Furosemide for Adults Hospitalized With Cirrhosis: the BUFF Trial",
"has_exemption": false,
"start_date": "2026-03-01",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Stacy Johnson",
"sponsor_slug": "stacy-johnson",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07226713",
"publication_url": "https://clinicaltrials.gov/study/NCT07226713",
"title": "A Single-Arm, Open-label, Phase II Study Evaluating Pacritinib in Participants With Metastatic Castrate-Resistant Prostate Cancer That Progressed on or After Prior Treatment With Androgen Receptor Signaling Inhibitors - (POSTPONE)",
"has_exemption": false,
"start_date": "2026-03-01",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07382596",
"publication_url": "https://clinicaltrials.gov/study/NCT07382596",
"title": "Cervical Plexus Hydrodissection With D5W Versus NS for Treatment-Resistant PTSD",
"has_exemption": false,
"start_date": "2026-03-01",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Dr. Dean Reeves Clinic",
"sponsor_slug": "dr-dean-reeves-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07187011",
"publication_url": "https://clinicaltrials.gov/study/NCT07187011",
"title": "Phase 2a Trial: Efficacy and Safety of PT150 in the Treatment of US Veterans With Posttraumatic Stress Disorder (PTSD)",
"has_exemption": false,
"start_date": "2026-04-01",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "San Diego Veterans Healthcare System",
"sponsor_slug": "san-diego-veterans-healthcare-system",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07016321",
"publication_url": "https://clinicaltrials.gov/study/NCT07016321",
"title": "Emetine for Viral Outbreaks: A Phase 2/3 Randomized, Double-Blinded, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Emetine for Dengue Fever (a.k.a. EVOLVE Antiviral Initiative)",
"has_exemption": false,
"start_date": "2026-05-01",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06708455",
"publication_url": "https://clinicaltrials.gov/study/NCT06708455",
"title": "Phase 2 Trial of Autologous Rapamycin-Resistant Th1/Tc1 (RAPA-201) Cell Therapy of PD-(L)1 Resistant Malignant Melanoma",
"has_exemption": false,
"start_date": "2027-03-01",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Rapa Therapeutics LLC",
"sponsor_slug": "rapa-therapeutics-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07042919",
"publication_url": "https://clinicaltrials.gov/study/NCT07042919",
"title": "A Phase Ib/II Study of Zanzalintinib in Second Line and Beyond for the Treatment of Advanced Hepatocellular Carcinoma",
"has_exemption": false,
"start_date": "2026-03-04",
"completion_date": "2029-03-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06112418",
"publication_url": "https://clinicaltrials.gov/study/NCT06112418",
"title": "A Randomized Comparison of Cleerly Coronary Artery Disease Stage-Based Care Versus Risk Factor-Based Care for Primary Prevention of Cardiovascular Events",
"has_exemption": false,
"start_date": "2024-03-06",
"completion_date": "2029-03-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Cleerly, Inc.",
"sponsor_slug": "cleerly-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06534983",
"publication_url": "https://clinicaltrials.gov/study/NCT06534983",
"title": "A Randomized Phase II, Double-blind, Multicenter Study Evaluating the Efficacy and Safety of Autogene Cevumeran Plus Nivolumab Versus Nivolumab as Adjuvant Therapy in Patients With High-risk Muscle-invasive Urothelial Carcinoma",
"has_exemption": false,
"start_date": "2024-12-09",
"completion_date": "2029-03-07",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227298",
"publication_url": "https://clinicaltrials.gov/study/NCT07227298",
"title": "AN INTERVENTIONAL OPEN-LABEL PHASE 1B/2 STUDY TO EVALUATE THE SAFETY, PHARMACOKINETICS, AND PRELIMINARY EFFICACY OF PF-08634404 IN COMBINATION WITH DIFFERENT ANTICANCER AGENTS IN PARTICIPANTS WITH ADVANCED SOLID TUMORS",
"has_exemption": false,
"start_date": "2026-01-30",
"completion_date": "2029-03-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05142696",
"publication_url": "https://clinicaltrials.gov/study/NCT05142696",
"title": "A Phase Ib/II Dose Finding Study Assessing Safety and Efficacy of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Extensive Stage Small Cell Lung Cancer (ES-SCLC) in Combination With Carboplatin, Etoposide, and Atezolizumab in Induction and With Atezolizumab in Maintenance Phase",
"has_exemption": false,
"start_date": "2022-07-13",
"completion_date": "2029-03-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05174169",
"publication_url": "https://clinicaltrials.gov/study/NCT05174169",
"title": "Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease",
"has_exemption": false,
"start_date": "2022-03-10",
"completion_date": "2029-03-10",
"has_results": false,
"results_due": false,
"sponsor_name": "NRG Oncology",
"sponsor_slug": "nrg-oncology",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06274528",
"publication_url": "https://clinicaltrials.gov/study/NCT06274528",
"title": "Effect of a Dual Orexin Receptor Antagonist on CSF Alzheimer's Disease Biomarkers",
"has_exemption": false,
"start_date": "2024-03-11",
"completion_date": "2029-03-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06883305",
"publication_url": "https://clinicaltrials.gov/study/NCT06883305",
"title": "A Randomised, Double-blind, Placebo-controlled, Parallel Group, Multicentre, Phase III Study to Evaluate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease",
"has_exemption": false,
"start_date": "2025-03-18",
"completion_date": "2029-03-13",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06878261",
"publication_url": "https://clinicaltrials.gov/study/NCT06878261",
"title": "A Randomised, Double-blind, Placebo-controlled, Parallel Group, Multicentre, Phase III Study to Evaluate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease",
"has_exemption": false,
"start_date": "2025-03-25",
"completion_date": "2029-03-13",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05827016",
"publication_url": "https://clinicaltrials.gov/study/NCT05827016",
"title": "A Phase 3, Two-stage, Randomized, Multi-center, Controlled, Open-label Study Comparing Iberdomide Maintenance to Lenalidomide Maintenance Therapy After Autologous Stem Cell Transplantation (ASCT) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) (EXCALIBER-Maintenance)",
"has_exemption": false,
"start_date": "2023-06-22",
"completion_date": "2029-03-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04305691",
"publication_url": "https://clinicaltrials.gov/study/NCT04305691",
"title": "A Phase 2 Trial of Ixazomib for Kaposi Sarcoma",
"has_exemption": false,
"start_date": "2023-11-07",
"completion_date": "2029-03-15",
"has_results": false,
"results_due": false,
"sponsor_name": "AIDS Malignancy Consortium",
"sponsor_slug": "aids-malignancy-consortium",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07225361",
"publication_url": "https://clinicaltrials.gov/study/NCT07225361",
"title": "Ublituximab (Briumvi) for Early Forms of Relapsing Multiple Sclerosis",
"has_exemption": false,
"start_date": "2025-11-28",
"completion_date": "2029-03-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06921785",
"publication_url": "https://clinicaltrials.gov/study/NCT06921785",
"title": "A Phase III, Randomised, Open-label, Sponsor-blinded, Multicentre Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma",
"has_exemption": false,
"start_date": "2025-05-06",
"completion_date": "2029-03-16",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07238400",
"publication_url": "https://clinicaltrials.gov/study/NCT07238400",
"title": "Cardiac Effects of Mineralocorticoid Receptor Antagonism After Preeclampsia",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2029-03-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05855200",
"publication_url": "https://clinicaltrials.gov/study/NCT05855200",
"title": "A Phase 3, Open-Label, Randomized Study of Perioperative Dostarlimab Monotherapy Versus Standard of Care in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer",
"has_exemption": false,
"start_date": "2023-08-01",
"completion_date": "2029-03-19",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06787950",
"publication_url": "https://clinicaltrials.gov/study/NCT06787950",
"title": "A Phase I/IIa Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Anti-tumor Activity of ASN-3186 in Patients with Advanced Solid Tumors.",
"has_exemption": false,
"start_date": "2025-02-20",
"completion_date": "2029-03-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Jiangsu Yahong Meditech Co., Ltd aka Asieris",
"sponsor_slug": "jiangsu-yahong-meditech-co-ltd-aka-asieris",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07316010",
"publication_url": "https://clinicaltrials.gov/study/NCT07316010",
"title": "Phase 2 Trial of Lisocabtagene Maraleucel for Minimal Residual Disease in Patients With Large B-cell Lymphoma",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2029-03-21",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06439082",
"publication_url": "https://clinicaltrials.gov/study/NCT06439082",
"title": "A Phase III, Multicenter, Randomized, Placebo Controlled, Double-blind Study to Assess Efficacy and Safety of Crizanlizumab (5 mg/kg) Versus Placebo, With or Without Hydroxyurea/Hydroxycarbamide Therapy, in Adolescent and Adult Sickle Cell Disease Patients With Frequent Vaso-Occlusive Crises",
"has_exemption": false,
"start_date": "2024-10-24",
"completion_date": "2029-03-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06669572",
"publication_url": "https://clinicaltrials.gov/study/NCT06669572",
"title": "A Phase II, Multi-center, Single Arm Trial of Lenvatinib Plus Pembrolizumab in Patients With Unresectable Locally Advanced and/or Metastatic Anorectal Squamous Cell Carcinoma (ASCC) After Progression on First Line Chemotherapy.",
"has_exemption": false,
"start_date": "2025-07-11",
"completion_date": "2029-03-26",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06843447",
"publication_url": "https://clinicaltrials.gov/study/NCT06843447",
"title": "A Phase 1b/2 Open-label, Multicenter Study to Evaluate the Safety and Efficacy of Raludotatug Deruxtecan With or Without Other Anticancer Investigational Agents in Participants With High-grade Serous Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Who Have Relapsed After Prior Platinum-based Chemotherapy",
"has_exemption": false,
"start_date": "2025-04-15",
"completion_date": "2029-03-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06347705",
"publication_url": "https://clinicaltrials.gov/study/NCT06347705",
"title": "Phase II Study Evaluating the Effects of Single Site Intratumoral Injections of Anti-CD40 Agonist Antibody (2141-V11) Given as Monotherapy Prior to Radical Prostatectomy to Men With Intermediate Risk Disease and in Combination With Androgen Deprivation Therapy for Those With High Risk Localized and Low Volume Metastatic Disease",
"has_exemption": false,
"start_date": "2024-03-28",
"completion_date": "2029-03-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07037862",
"publication_url": "https://clinicaltrials.gov/study/NCT07037862",
"title": "A 2-Part, Randomized, Double-Blind, Placebo-Controlled Study in Participants With Duchenne Muscular Dystrophy Amenable to Exon 44 Skipping With an Initial Multiple Ascending Dose Part A to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ENTR-601-44, Followed by Part B to Evaluate the Safety and Efficacy of ENTR-601-44 (ELEVATE-44)",
"has_exemption": false,
"start_date": "2025-06-30",
"completion_date": "2029-03-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Entrada Therapeutics, Inc.",
"sponsor_slug": "entrada-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06997497",
"publication_url": "https://clinicaltrials.gov/study/NCT06997497",
"title": "A Phase 3, Randomized, Open-label, Multicenter Clinical Study to Evaluate the Safety and Efficacy of MK-1084, Cetuximab, and mFOLFOX6 Versus mFOLFOX6 With or Without Bevacizumab as First-line Treatment of Participants With KRAS G12C-mutant, Locally Advanced Unresectable or Metastatic Colorectal Cancer (KANDLELIT-012)",
"has_exemption": false,
"start_date": "2025-07-16",
"completion_date": "2029-03-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07430956",
"publication_url": "https://clinicaltrials.gov/study/NCT07430956",
"title": "A Master Protocol for a Phase 3, Randomized, Multicenter, Double-blind Study to Assess Stroke and Systemic Embolism Prevention With REGN7508 and REGN9933, Monoclonal Antibodies Against Factor XI, Versus Placebo in Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable (ROXI-INCLINE)",
"has_exemption": false,
"start_date": "2026-03-18",
"completion_date": "2029-03-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07192614",
"publication_url": "https://clinicaltrials.gov/study/NCT07192614",
"title": "A Phase I/II Open-label, Dose Escalation and Dose Expansion Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of AZD6621, a T Cell-engaging Antibody That Targets STEAP2, CD3, and CD8 in Adult Participants With Metastatic Prostate Cancer",
"has_exemption": false,
"start_date": "2025-09-30",
"completion_date": "2029-03-29",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07046910",
"publication_url": "https://clinicaltrials.gov/study/NCT07046910",
"title": "Advanced Immunoclinical Phenotyping of Rejection in Lung Transplant",
"has_exemption": false,
"start_date": "2019-04-01",
"completion_date": "2029-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Virginia",
"sponsor_slug": "university-of-virginia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05039515",
"publication_url": "https://clinicaltrials.gov/study/NCT05039515",
"title": "A Phase 2 Study to Assess the Efficacy and Safety of 2 Dosage Regimens of Oral Fidrisertib (IPN60130) for the Treatment of Fibrodysplasia Ossificans Progressiva in Male and Female Paediatric and Adult Participants.",
"has_exemption": false,
"start_date": "2021-12-01",
"completion_date": "2029-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Clementia Pharmaceuticals Inc.",
"sponsor_slug": "clementia-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05651594",
"publication_url": "https://clinicaltrials.gov/study/NCT05651594",
"title": "A Phase 2 Trial of Chemotherapy, Pembrolizumab, and Propranolol in Advanced Esophageal/Gastroesophageal Junction Adenocarcinoma Patients",
"has_exemption": false,
"start_date": "2023-03-07",
"completion_date": "2029-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Roswell Park Cancer Institute",
"sponsor_slug": "roswell-park-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06380751",
"publication_url": "https://clinicaltrials.gov/study/NCT06380751",
"title": "A Randomised, Open-Label, Phase III Study of Saruparib (AZD5305) Plus Camizestrant Compared With Physician's Choice CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant for the First-Line Treatment of Patients With BRCA1, BRCA2, or PALB2 Mutations and Hormone Receptor Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified) Advanced Breast Cancer (EvoPAR-Breast01)",
"has_exemption": false,
"start_date": "2024-08-01",
"completion_date": "2029-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06778434",
"publication_url": "https://clinicaltrials.gov/study/NCT06778434",
"title": "Acid Sphingomyelinase Inhibition to Mitigate the Environmental Exposure Risks of Ultraviolet Light-Induced Actinic Neoplasia and Squamous Cell Carcinoma in US Veterans",
"has_exemption": false,
"start_date": "2025-04-01",
"completion_date": "2029-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06814145",
"publication_url": "https://clinicaltrials.gov/study/NCT06814145",
"title": "A Phase 2, Multicenter, Double-blind, Extension Study to Evaluate the Effects of Sotatercept for the Treatment of Combined Postcapillary and Precapillary Pulmonary Hypertension (Cpc-PH) Due to Heart Failure With Preserved Ejection Fraction (HFpEF)",
"has_exemption": false,
"start_date": "2025-04-16",
"completion_date": "2029-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06918431",
"publication_url": "https://clinicaltrials.gov/study/NCT06918431",
"title": "A Phase 2 Study Evaluating the Safety and Efficacy of Asparaginase Erwinia Chrysanthemi- Recombinant-Rywn (Recombinant Erwinia Asparaginase) During Pediatric-Inspired Regimen in High-Risk Adults With Newly Diagnosed ALL or LBL",
"has_exemption": false,
"start_date": "2025-10-10",
"completion_date": "2029-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "City of Hope Medical Center",
"sponsor_slug": "city-of-hope-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07394036",
"publication_url": "https://clinicaltrials.gov/study/NCT07394036",
"title": "The Effect of Ipratropium Bromide on Exercise-Induced Laryngeal Obstruction (EILO) in Pediatric Patients",
"has_exemption": false,
"start_date": "2026-03-16",
"completion_date": "2029-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Cook Children's Health Care System",
"sponsor_slug": "cook-childrens-health-care-system",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07413939",
"publication_url": "https://clinicaltrials.gov/study/NCT07413939",
"title": "A Two-part, Seamless, Multicenter, Randomized, Open-label, Adaptive Phase II/III Study of the Blood-brain Barrier Penetrant RO7771950 Versus Tucatinib, Both in Combination With Trastuzumab and Capecitabine, in Patients With Pretreated Unresectable Locally Advanced or Metastatic HER2-Postivie Breast Cancer, With or Without Central Nervous System Metastases",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2029-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT00185744",
"publication_url": "https://clinicaltrials.gov/study/NCT00185744",
"title": "Accelerated Partial Breast Irradiation Following Lumpectomy for Breast Cancer",
"has_exemption": false,
"start_date": "2002-09-30",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03153475",
"publication_url": "https://clinicaltrials.gov/study/NCT03153475",
"title": "Multi-Center Clinical Evaluation of the ATTUNE® Revision System in Revision Total Knee Arthroplasty",
"has_exemption": false,
"start_date": "2017-05-30",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "DePuy Orthopaedics",
"sponsor_slug": "depuy-orthopaedics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03167203",
"publication_url": "https://clinicaltrials.gov/study/NCT03167203",
"title": "A Safety Surveillance Study of Events of Special Interest Occurring in Subjects With Macular Degenerative Disease Treated With Human Embryonic Stem Cell-derived Retinal Pigment Epithelial Cell Therapy",
"has_exemption": false,
"start_date": "2018-01-08",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Astellas Institute for Regenerative Medicine",
"sponsor_slug": "astellas-institute-for-regenerative-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03493425",
"publication_url": "https://clinicaltrials.gov/study/NCT03493425",
"title": "Phase II Randomized Trial of Neo-Adjuvant Chemotherapy Followed by Surgery and Post-Operative Radiation Versus Surgery and Post-Operative Radiation for Organ Preservation of T3 and T4a Nasal and Paranasal Sinus Squamous Cell Carcinoma (NPNSCC)",
"has_exemption": false,
"start_date": "2019-03-12",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ECOG-ACRIN Cancer Research Group",
"sponsor_slug": "ecog-acrin-cancer-research-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04333576",
"publication_url": "https://clinicaltrials.gov/study/NCT04333576",
"title": "A Phase 3b Study to Evaluate the Safety and Efficacy of Elagolix in Combination With Combined Oral Contraceptives in Premenopausal Women With Documented Endometriosis and Associated Moderate to Severe Pain",
"has_exemption": false,
"start_date": "2020-08-10",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04740476",
"publication_url": "https://clinicaltrials.gov/study/NCT04740476",
"title": "An Open-Label Extension Study for Patients With Dravet Syndrome Who Previously Participated in Studies of STK-001",
"has_exemption": false,
"start_date": "2021-01-20",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stoke Therapeutics, Inc",
"sponsor_slug": "stoke-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04884815",
"publication_url": "https://clinicaltrials.gov/study/NCT04884815",
"title": "An Operationally Seamless Phase 1/2/3 Study Consisting of a Safety and Dose-finding Phase 1/2 and Randomized, Open-label, Active-controlled Phase 3 to Evaluate UX701 AAV Gene Therapy in Adults With Wilson Disease",
"has_exemption": false,
"start_date": "2021-09-27",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ultragenyx Pharmaceutical Inc",
"sponsor_slug": "ultragenyx-pharmaceutical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05127226",
"publication_url": "https://clinicaltrials.gov/study/NCT05127226",
"title": "HALOS: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intrathecally Administered ION582 in Patients With Angelman Syndrome",
"has_exemption": false,
"start_date": "2021-12-22",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ionis Pharmaceuticals, Inc.",
"sponsor_slug": "ionis-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05595473",
"publication_url": "https://clinicaltrials.gov/study/NCT05595473",
"title": "A Phase 1/2a, Open-label, Multicenter, Dose Escalation and Dose Expansion Study Evaluating the Safety, Tolerability and Efficacy of RZ-001 in Combination with Valganciclovir in Subjects with Hepatocellular Carcinoma",
"has_exemption": false,
"start_date": "2022-07-29",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Rznomics, Inc.",
"sponsor_slug": "rznomics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05619146",
"publication_url": "https://clinicaltrials.gov/study/NCT05619146",
"title": "Upper and Lower Extremity Cycling in Incomplete Spinal Cord Injury Individuals to Promote Limb Recovery",
"has_exemption": false,
"start_date": "2023-01-23",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Shirley Ryan AbilityLab",
"sponsor_slug": "shirley-ryan-abilitylab",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05721755",
"publication_url": "https://clinicaltrials.gov/study/NCT05721755",
"title": "Phase III Randomized Trial of Immunotherapy With or Without Consolidative Radiotherapy for Oligometastatic Head and Neck Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2023-06-08",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ECOG-ACRIN Cancer Research Group",
"sponsor_slug": "ecog-acrin-cancer-research-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06305286",
"publication_url": "https://clinicaltrials.gov/study/NCT06305286",
"title": "A Pilot Study Assessing the Safety of Using a Monoclonal Antibody Against Cluster of Differentiation 40 (CD40) Ligand to Achieve a Calcineurin Inhibitor-free Immunosuppression Regimen in Patients With Type 1 Diabetes Mellitus (T1D) and Problematic Hypoglycemia Undergoing Islet Cell Transplantation",
"has_exemption": false,
"start_date": "2024-03-04",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06292013",
"publication_url": "https://clinicaltrials.gov/study/NCT06292013",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) Who Have Established Atherosclerotic Cardiovascular Disease or Are at Risk for a First Cardiovascular Event - ACCLAIM-Lp(a)",
"has_exemption": false,
"start_date": "2024-03-05",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06350318",
"publication_url": "https://clinicaltrials.gov/study/NCT06350318",
"title": "A Phase 2 Open-Label, Multicenter Study of Rituximab and Zanubrutinib in Patients With Indolent B-cell Lymphomas",
"has_exemption": false,
"start_date": "2024-04-19",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05977400",
"publication_url": "https://clinicaltrials.gov/study/NCT05977400",
"title": "NICU Antibiotics and Outcomes Follow-Up Study",
"has_exemption": false,
"start_date": "2024-04-30",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sharp HealthCare",
"sponsor_slug": "sharp-healthcare",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06395103",
"publication_url": "https://clinicaltrials.gov/study/NCT06395103",
"title": "LIGHTBEAM-U01 Substudy 01A: A Phase 1/2 Substudy to Evaluate the Safety and Efficacy of Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors",
"has_exemption": false,
"start_date": "2024-08-16",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06102525",
"publication_url": "https://clinicaltrials.gov/study/NCT06102525",
"title": "A Phase 1/2a, Open-label, Multicenter, Dose Escalation and Dose Expansion Study Evaluating the Safety, Tolerability, and Efficacy of RZ-001 in Combination With Valganciclovir in Subjects With Glioblastoma",
"has_exemption": false,
"start_date": "2024-10-08",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Rznomics, Inc.",
"sponsor_slug": "rznomics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06798558",
"publication_url": "https://clinicaltrials.gov/study/NCT06798558",
"title": "Phase II Study of Neoadjuvant Lu-177-PSMA-617 in Patients With High Risk Localized Prostate Cancer Undergoing Radical Prostatectomy",
"has_exemption": false,
"start_date": "2025-03-05",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hackensack Meridian Health",
"sponsor_slug": "hackensack-meridian-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06542705",
"publication_url": "https://clinicaltrials.gov/study/NCT06542705",
"title": "Effect of Internal Brace on Outcomes Following ACL Reconstruction With Bone Patellar Bone (BTB) Autograft: A Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2025-03-17",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06647953",
"publication_url": "https://clinicaltrials.gov/study/NCT06647953",
"title": "Prospective Treatment of Types I, II and III Pleuropulmonary Blastoma (PPB)",
"has_exemption": false,
"start_date": "2025-03-21",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06880770",
"publication_url": "https://clinicaltrials.gov/study/NCT06880770",
"title": "Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Plozasiran in Adults With Severe Hypertriglyceridemia at High Risk of Acute Pancreatitis (SHASTA-5 Study)",
"has_exemption": false,
"start_date": "2025-04-24",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Arrowhead Pharmaceuticals",
"sponsor_slug": "arrowhead-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06682793",
"publication_url": "https://clinicaltrials.gov/study/NCT06682793",
"title": "A Seamless Phase 1/2 Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated Tmod™ CAR T, in Heterozygous HLA-A*02 Adults With Recurrent Unresectable, Locally Advanced, or Metastatic Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression",
"has_exemption": false,
"start_date": "2025-05-22",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "A2 Biotherapeutics Inc.",
"sponsor_slug": "a2-biotherapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06839235",
"publication_url": "https://clinicaltrials.gov/study/NCT06839235",
"title": "A Phase 1/2 Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of ABO-101 in Participants With Primary Hyperoxaluria Type 1 (PH1)",
"has_exemption": false,
"start_date": "2025-06-16",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Arbor Biotechnologies",
"sponsor_slug": "arbor-biotechnologies",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07098988",
"publication_url": "https://clinicaltrials.gov/study/NCT07098988",
"title": "A Ph2, Randomized, Blinded, Placebo-Controlled Trial Investigating the Efficacy and Safety of Visugromab Versus Placebo, in Combination With Pembrolizumab, Pemetrexed, and Carboplatin, in 1L Treatment of Participants With Metastatic NSCLC (GDFATHER-NSCLC-01)",
"has_exemption": false,
"start_date": "2025-08-01",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "CatalYm GmbH",
"sponsor_slug": "catalym-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07145736",
"publication_url": "https://clinicaltrials.gov/study/NCT07145736",
"title": "Moxidectin Versus Ivermectin as Mass Drug Administration for the Control of Onchocerciasis and Other Neglected Tropical Diseases: A Cluster-randomised Trial",
"has_exemption": false,
"start_date": "2025-08-04",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kirby Institute",
"sponsor_slug": "kirby-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07016698",
"publication_url": "https://clinicaltrials.gov/study/NCT07016698",
"title": "A Prospective, Multicenter, Single Arm, Real-World Registry Assessing the Clinical Use of the Rotarex(TM) Rotational Excisional Atherectomy System (XTRACT Registry)",
"has_exemption": false,
"start_date": "2025-09-29",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "C. R. Bard",
"sponsor_slug": "c-r-bard",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07132918",
"publication_url": "https://clinicaltrials.gov/study/NCT07132918",
"title": "The cARdiac Radiation Therapy Sparing (HEARTS) for Thoracic Cancers",
"has_exemption": false,
"start_date": "2025-10-08",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07218783",
"publication_url": "https://clinicaltrials.gov/study/NCT07218783",
"title": "A Prospective, Multicenter, Randomized, Masked, Controlled Study to Evaluate the Safety and Efficacy of the Bimatoprost Implant System (78 mcg) Used in Combination With the SpyGlass IOL Compared to Timolol Maleate Ophthalmic Solution, USP, 0.5%,",
"has_exemption": false,
"start_date": "2025-10-15",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "SpyGlass Pharma, Inc.",
"sponsor_slug": "spyglass-pharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06844383",
"publication_url": "https://clinicaltrials.gov/study/NCT06844383",
"title": "A Randomized Open-label Phase 2 Study of TALazoparib With or Without ENzaluTamide in Patients With Metastatic Castration-Resistant Prostate Cancer and HRR Mutations After Progression on Abiraterone Acetate",
"has_exemption": false,
"start_date": "2025-10-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Prostate Cancer Clinical Trials Consortium",
"sponsor_slug": "prostate-cancer-clinical-trials-consortium",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07135050",
"publication_url": "https://clinicaltrials.gov/study/NCT07135050",
"title": "Phase 1/2 First-in-Human Study to Evaluate the Safety, Tolerability, and Efficacy of MZ-1866, an AAV-9 Gene Therapy Delivered by Intracerebroventricular Injection to Participants With Pitt Hopkins Syndrome",
"has_exemption": false,
"start_date": "2025-12-19",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mahzi Therapeutics",
"sponsor_slug": "mahzi-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07209332",
"publication_url": "https://clinicaltrials.gov/study/NCT07209332",
"title": "An Open-Label Extension Study to Investigate the Long-term Safety, Tolerability, Pharmacokinetics, and Efficacy of WVE-N531 in Patients With Duchenne Muscular Dystrophy Who Participated in Another Study of WVE-N531",
"has_exemption": false,
"start_date": "2025-12-28",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Wave Life Sciences Ltd.",
"sponsor_slug": "wave-life-sciences-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227207",
"publication_url": "https://clinicaltrials.gov/study/NCT07227207",
"title": "A Phase 1/2, Open-Label, Multi-Center, Dose Escalation, Dose Expansion, and Single Repeat Dose Study of TSRA-196 in Adults With the PiZZ Genotype Who Have Lung and/or Liver Disease Associated With Severe Alpha-1 Antitrypsin Deficiency",
"has_exemption": false,
"start_date": "2025-12-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Tessera Therapeutics, Inc.",
"sponsor_slug": "tessera-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07262619",
"publication_url": "https://clinicaltrials.gov/study/NCT07262619",
"title": "A Multicenter, Multi-Part, Phase 1/2 Study of EIK1005 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors, Including Checkpoint Inhibitor Naïve Participants With Microsatellite Instability High (MSI-H) or Mismatch Repair Deficient (dMMR) Tumors",
"has_exemption": false,
"start_date": "2026-01-22",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eikon Therapeutics",
"sponsor_slug": "eikon-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07439653",
"publication_url": "https://clinicaltrials.gov/study/NCT07439653",
"title": "A Phase 1/2, First-in-Human, Open-Label, Multicenter Study of TORL-5-700 as a Monotherapy and in Combination for Participants With Relapsed or Refractory Non-Hodgkin Lymphoma",
"has_exemption": false,
"start_date": "2026-01-30",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "TORL Biotherapeutics, LLC",
"sponsor_slug": "torl-biotherapeutics-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06155682",
"publication_url": "https://clinicaltrials.gov/study/NCT06155682",
"title": "Cognitive and Neural Correlates of TMS Motor Intracortical Inhibition in Schizophrenia",
"has_exemption": false,
"start_date": "2026-02-02",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Maryland, Baltimore",
"sponsor_slug": "university-of-maryland-baltimore",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07436689",
"publication_url": "https://clinicaltrials.gov/study/NCT07436689",
"title": "A Multicenter, Open-Label, Long-Term Extension Study for Oral Levosimendan (TNX-103)",
"has_exemption": false,
"start_date": "2026-03-13",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Tenax Therapeutics, Inc.",
"sponsor_slug": "tenax-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06240455",
"publication_url": "https://clinicaltrials.gov/study/NCT06240455",
"title": "A Double-blind, Placebo-controlled, Phase 2 Dose-range Study to Assess the Efficacy and Safety of WP1302 in Preventing Disease Relapse Following Methimazole Withdrawal in Subjects With Graves' Disease",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Worg Biotherapeutics Inc.",
"sponsor_slug": "worg-biotherapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07224763",
"publication_url": "https://clinicaltrials.gov/study/NCT07224763",
"title": "EXTEND: A Prospective Study to Evaluate the Safety and Efficacy of GGTA1 KO Thymokidney XenoTransplantation in Patients With End-stage Renal Disease (ESRD)",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "United Therapeutics",
"sponsor_slug": "united-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07277738",
"publication_url": "https://clinicaltrials.gov/study/NCT07277738",
"title": "Precision Supplemental Imaging in Women With Dense Breasts (PSID Trial)",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07288437",
"publication_url": "https://clinicaltrials.gov/study/NCT07288437",
"title": "Adaptive Deep Brain Stimulation Targeting the Dentate Nucleus to Treat Spinocerebellar Ataxia",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07392957",
"publication_url": "https://clinicaltrials.gov/study/NCT07392957",
"title": "A Phase IB/II Open-label Study of the Safety and Preliminary Efficacy of CTX-009 Administered Either as a Monotherapy or in Combination With CTX-471 in Patients With Recurrent Glioblastoma",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07413744",
"publication_url": "https://clinicaltrials.gov/study/NCT07413744",
"title": "Probiotic Supplementation Safety and Feasibility Study in Preclinical Alzheimer's Disease",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07423078",
"publication_url": "https://clinicaltrials.gov/study/NCT07423078",
"title": "A Phase II Window of Opportunity in Preserving Laryngeal Function (WOLF) Trial",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Matthew Spector",
"sponsor_slug": "matthew-spector",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07450859",
"publication_url": "https://clinicaltrials.gov/study/NCT07450859",
"title": "A Phase 2 Study of BT5528 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "BicycleTx Limited",
"sponsor_slug": "bicycletx-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07459660",
"publication_url": "https://clinicaltrials.gov/study/NCT07459660",
"title": "An Open-Label Study to Assess the Long-Term Safety and Tolerability of ML007C-MA in Adult Participants With Hallucinations and Delusions Associated With Alzheimer's Disease Psychosis",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "MapLight Therapeutics",
"sponsor_slug": "maplight-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07060417",
"publication_url": "https://clinicaltrials.gov/study/NCT07060417",
"title": "The Effects of SGLT2 Inhibition on Vascular Health and Physical Function in Veterans With CKD",
"has_exemption": false,
"start_date": "2026-04-01",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07104318",
"publication_url": "https://clinicaltrials.gov/study/NCT07104318",
"title": "Randomized Clinical Trial of Personalized vs Standard of Care Treatment for Helicobacter Pylori Eradication Among Veterans: \"VA Eradicate HP\"",
"has_exemption": false,
"start_date": "2026-04-01",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07078838",
"publication_url": "https://clinicaltrials.gov/study/NCT07078838",
"title": "A Randomized, Window of Opportunity Trial of Tirzepatide in Women With Obesity and a Diagnosis of Endometrial Intra-epithelial Neoplasia (EIN) or Grade 1 Endometrial Cancer",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "UNC Lineberger Comprehensive Cancer Center",
"sponsor_slug": "unc-lineberger-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07293546",
"publication_url": "https://clinicaltrials.gov/study/NCT07293546",
"title": "An Open-Label First-in-Human Phase 1/2 Study to Evaluate the Safety, Tolerability, and Efficacy of FRF-001, an AAV-9 Gene Therapy Administered by Intracerebroventricular Injection in Participants With FOXG1 Syndrome",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "FOXG1 Research Foundation",
"sponsor_slug": "foxg1-research-foundation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07021989",
"publication_url": "https://clinicaltrials.gov/study/NCT07021989",
"title": "Pembrolizumab and GVD With ctDNA-guided Consolidation in Patients With Relapsed or Refractory Classic Hodgkin Lymphoma: A Multicenter Phase 2 Study of the University of California Hematologic Malignancies Consortium",
"has_exemption": false,
"start_date": "2026-05-01",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Michael Spinner, MD",
"sponsor_slug": "michael-spinner-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06855043",
"publication_url": "https://clinicaltrials.gov/study/NCT06855043",
"title": "Pilot Randomized Controlled Trial of Late Surfactant Therapy With Budesonide for Prevention of Bronchopulmonary Dysplasia",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06167213",
"publication_url": "https://clinicaltrials.gov/study/NCT06167213",
"title": "Safety and Effectiveness of Balloon-Expandable Bioprosthetic SAPIEN X4 Transcatheter Heart Valve - Mitral",
"has_exemption": false,
"start_date": "2027-01-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Edwards Lifesciences",
"sponsor_slug": "edwards-lifesciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04364178",
"publication_url": "https://clinicaltrials.gov/study/NCT04364178",
"title": "Viral Specific T-Lymphocytes by Cytokine Capture System (CCS) to Treat Infection With Adenovirus or Cytomegalovirus After Hematopoietic Cell Transplantation or Solid Organ Transplantation and in Patients With Compromised Immunity",
"has_exemption": false,
"start_date": "2020-08-12",
"completion_date": "2029-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Jessie L. Alexander",
"sponsor_slug": "jessie-l-alexander",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04682158",
"publication_url": "https://clinicaltrials.gov/study/NCT04682158",
"title": "Propranolol With Standard Chemoradiation for Esophageal Adenocarcinoma A Phase II Study",
"has_exemption": false,
"start_date": "2021-04-01",
"completion_date": "2029-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Roswell Park Cancer Institute",
"sponsor_slug": "roswell-park-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06499805",
"publication_url": "https://clinicaltrials.gov/study/NCT06499805",
"title": "Barriers and Facilitators to OTC Hearing Aids Success",
"has_exemption": false,
"start_date": "2025-03-15",
"completion_date": "2029-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Yu-Hsiang Wu",
"sponsor_slug": "yu-hsiang-wu",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06828991",
"publication_url": "https://clinicaltrials.gov/study/NCT06828991",
"title": "ctDNA-Guided Mosunetuzumab Consolidation Therapy in Older Patients With Untreated DLBCL",
"has_exemption": false,
"start_date": "2025-09-04",
"completion_date": "2029-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Danielle Wallace",
"sponsor_slug": "danielle-wallace",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06834217",
"publication_url": "https://clinicaltrials.gov/study/NCT06834217",
"title": "Characterization and Modulation of Functional Connectivity and Fear Extinction Abnormalities in Obsessive-Compulsive Disorder",
"has_exemption": false,
"start_date": "2025-09-12",
"completion_date": "2029-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06574009",
"publication_url": "https://clinicaltrials.gov/study/NCT06574009",
"title": "Better Options for Chronic Cancer Pain: a SMART Study",
"has_exemption": false,
"start_date": "2025-10-07",
"completion_date": "2029-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06863402",
"publication_url": "https://clinicaltrials.gov/study/NCT06863402",
"title": "Nemtabrutinib and Pembrolizumab in Patients With Richter Transformation: A Phase II Study",
"has_exemption": false,
"start_date": "2026-02-15",
"completion_date": "2029-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Roswell Park Cancer Institute",
"sponsor_slug": "roswell-park-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07169734",
"publication_url": "https://clinicaltrials.gov/study/NCT07169734",
"title": "A Phase I/II, Open-label, Multicenter Study of ALE.P03 (Claudin-1 Targeted Antibody-drug Conjugate) as a Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors",
"has_exemption": false,
"start_date": "2025-08-26",
"completion_date": "2029-04-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Alentis Therapeutics AG",
"sponsor_slug": "alentis-therapeutics-ag",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07098338",
"publication_url": "https://clinicaltrials.gov/study/NCT07098338",
"title": "An Open-Label, Multi-Drug, Multi-Centre, Phase II Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumour Activity of Novel Combinations in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (LIBRA)",
"has_exemption": false,
"start_date": "2025-08-07",
"completion_date": "2029-04-06",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06894511",
"publication_url": "https://clinicaltrials.gov/study/NCT06894511",
"title": "A Phase II, Open-label, Multi-Center, Randomized Study Comparing the Combination of Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) and Androgen Receptor Pathway Inhibitor (ARPI) vs. Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in First-line Treatment of Patients With Prostate-Specific Membrane Antigen (PSMA)-Positive Progressive Metastatic Castration Resistant Prostate Cancer (mCRPC)",
"has_exemption": false,
"start_date": "2025-09-11",
"completion_date": "2029-04-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07266831",
"publication_url": "https://clinicaltrials.gov/study/NCT07266831",
"title": "A Phase 2/3, Randomized, Active-Controlled, Open-Label (Phase 2) and Double-Blind (Phase 3) Study to Evaluate the Antiretroviral Activity, Safety, and Tolerability of Islatravir (ISL) and Ulonivirine (ULO) Once Weekly Compared With Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF) Once Daily in Treatment-Naïve Adult Participants Living With HIV-1",
"has_exemption": false,
"start_date": "2025-12-18",
"completion_date": "2029-04-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07354100",
"publication_url": "https://clinicaltrials.gov/study/NCT07354100",
"title": "Bifidobacterium Lactulose Optimization in Oncology and Microbiome (BLOOM)",
"has_exemption": false,
"start_date": "2026-12-15",
"completion_date": "2029-04-13",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05739383",
"publication_url": "https://clinicaltrials.gov/study/NCT05739383",
"title": "A Randomized, Double-blind, Placebo-controlled Multicenter Study to Evaluate the Effect of Inclisiran on Preventing Major Adverse Cardiovascular Events in High-risk Primary Prevention Patients (VICTORION-1 PREVENT)",
"has_exemption": false,
"start_date": "2023-03-09",
"completion_date": "2029-04-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06740526",
"publication_url": "https://clinicaltrials.gov/study/NCT06740526",
"title": "A Phase 2b, Multicenter, Open-label, Single-arm Trial to Evaluate the Impact of Sibeprenlimab on Kidney Histopathology Through Repeat Kidney Biopsies in Adolescents and Adults With Immunoglobulin A Nephropathy",
"has_exemption": false,
"start_date": "2024-11-19",
"completion_date": "2029-04-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Otsuka Pharmaceutical Development & Commercialization, Inc.",
"sponsor_slug": "otsuka-pharmaceutical-development-commercialization-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07092514",
"publication_url": "https://clinicaltrials.gov/study/NCT07092514",
"title": "Randomized Phase II Trial of Lenvatinib 24 mg/Day Versus 10 mg/Day to Treat Symptomatic or Progressive Radioactive Iodine Resistant (RAIR) Differentiated Thyroid Cancer (DTC)",
"has_exemption": false,
"start_date": "2025-10-14",
"completion_date": "2029-04-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07325136",
"publication_url": "https://clinicaltrials.gov/study/NCT07325136",
"title": "A Phase 1/2 Study of BMS-986525 as Monotherapy and in Combination With Nivolumab in Participants With Relapsed/Refractory Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2026-02-03",
"completion_date": "2029-04-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04822181",
"publication_url": "https://clinicaltrials.gov/study/NCT04822181",
"title": "The Effect of Semaglutide in Subjects With Non-cirrhotic Non-alcoholic Steatohepatitis",
"has_exemption": false,
"start_date": "2021-04-01",
"completion_date": "2029-04-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Novo Nordisk A/S",
"sponsor_slug": "novo-nordisk-as",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05406401",
"publication_url": "https://clinicaltrials.gov/study/NCT05406401",
"title": "A Multicenter, Open-label, Phase 2 Dose Escalation and Confirmation, and Efficacy Expansion Study of Zilovertamab Vedotin (MK-2140) in Combination With R-CHP in Participants With DLBCL (waveLINE)",
"has_exemption": false,
"start_date": "2022-07-14",
"completion_date": "2029-04-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06764875",
"publication_url": "https://clinicaltrials.gov/study/NCT06764875",
"title": "A Randomized, Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan Versus Trastuzumab, Chemotherapy, and Pembrolizumab for the First Line Treatment of HER2-positive Gastric Cancer (ARTEMIDE-Gastric01)",
"has_exemption": false,
"start_date": "2025-03-01",
"completion_date": "2029-04-27",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06824467",
"publication_url": "https://clinicaltrials.gov/study/NCT06824467",
"title": "A Phase 3, Randomized, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan Maintenance Treatment With or Without Bevacizumab Versus Standard of Care After Second-line Platinum-based Doublet Chemotherapy in Participants With Platinum-sensitive Recurrent Ovarian Cancer (TroFuse-022/ENGOT-ov84/GOG-3103)",
"has_exemption": false,
"start_date": "2025-04-09",
"completion_date": "2029-04-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07284433",
"publication_url": "https://clinicaltrials.gov/study/NCT07284433",
"title": "A Single-arm, Multicenter, Open-label, Phase I/II Trial of Allo-QuadCAR01-T, an Allogeneic CAR-T-cell Therapy Targeting CD19 and CD20, for the Treatment of Relapsed or Refractory B-cell Malignancies",
"has_exemption": false,
"start_date": "2026-01-06",
"completion_date": "2029-04-27",
"has_results": false,
"results_due": false,
"sponsor_name": "AvenCell Therapeutics, Inc.",
"sponsor_slug": "avencell-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07366034",
"publication_url": "https://clinicaltrials.gov/study/NCT07366034",
"title": "A Study to Evaluate the Dose-exposure, Safety, and Exploratory Efficacy of Nerandomilast in Children and Adolescents From 2 Years to Less Than 18 Years of Age With Fibrosing Interstitial Lung Disease (Part A: Double-blind, Placebo-controlled in Children From 6 to Less Than 18 Years of Age and Open-label Active Treatment in Children From 2 to Less Than 6 Years of Age), Followed by an Open-label Phase With Active Treatment (Part B)",
"has_exemption": false,
"start_date": "2026-07-27",
"completion_date": "2029-04-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Boehringer Ingelheim",
"sponsor_slug": "boehringer-ingelheim",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04156893",
"publication_url": "https://clinicaltrials.gov/study/NCT04156893",
"title": "RH Genotype Matched Red Cell Transfusions for Patients With Sickle Cell Disease",
"has_exemption": false,
"start_date": "2020-01-30",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Hospital of Philadelphia",
"sponsor_slug": "childrens-hospital-of-philadelphia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04684940",
"publication_url": "https://clinicaltrials.gov/study/NCT04684940",
"title": "A Phase 1/2 Safety, Tolerability, and Efficacy Study of BMN 270, an Adeno-Associated Virus Vector-Mediated Gene Transfer of Human Factor VIII in Hemophilia A Patients With Active or Prior Inhibitors",
"has_exemption": false,
"start_date": "2020-12-10",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "BioMarin Pharmaceutical",
"sponsor_slug": "biomarin-pharmaceutical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04534205",
"publication_url": "https://clinicaltrials.gov/study/NCT04534205",
"title": "An Open-label Phase II/III Randomized Trial of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Monotherapy as a First Line Therapy in Patients With Unresectable Recurrent, or Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC) Which is Positive for Human Papilloma Virus 16 (HPV16+) and Expresses PD-L1",
"has_exemption": false,
"start_date": "2021-01-07",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Biontech SE",
"sponsor_slug": "biontech-se",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04822337",
"publication_url": "https://clinicaltrials.gov/study/NCT04822337",
"title": "A Phase I/II Study of Carfilzomib, Lenalidomide, Dexamethasone and the Anti-B-Cell Maturation Antigen (BCMA) Antibody Drug Conjugate Belantamab Mafodotin in Multiple Myeloma",
"has_exemption": false,
"start_date": "2021-05-19",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04770870",
"publication_url": "https://clinicaltrials.gov/study/NCT04770870",
"title": "Post Approval Study 2: Hintermann Series H3 Total Ankle Replacement System",
"has_exemption": false,
"start_date": "2022-02-01",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "DT MedTech, LLC",
"sponsor_slug": "dt-medtech-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05362760",
"publication_url": "https://clinicaltrials.gov/study/NCT05362760",
"title": "Combination of Abemaciclib and Endocrine Therapy in Hormone Receptor Positive HER2 Negative Locally Advanced or Metastatic Breast Cancer With Focus on Digital Side Effect Management. The MINERVA Trial - A Phase IV Trial",
"has_exemption": false,
"start_date": "2022-04-27",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Prof. Wolfgang Janni",
"sponsor_slug": "prof-wolfgang-janni",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05484115",
"publication_url": "https://clinicaltrials.gov/study/NCT05484115",
"title": "Randomized Controlled Clinical Trial on the Application of Heli-FX EndoAnchors in Conjunction With the Endurant II/IIs Endograft in Infrarenal Aortic Aneurysms With a Wide Infrarenal Neck (HERCULES Trial)",
"has_exemption": false,
"start_date": "2023-05-26",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Rijnstate Hospital",
"sponsor_slug": "rijnstate-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05701241",
"publication_url": "https://clinicaltrials.gov/study/NCT05701241",
"title": "Continuing Somatostatin Analogues Upon Progression in Neuroendocrine Tumour pAtients - The SAUNA Trial",
"has_exemption": false,
"start_date": "2023-06-28",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University Hospital, Antwerp",
"sponsor_slug": "university-hospital-antwerp",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05995353",
"publication_url": "https://clinicaltrials.gov/study/NCT05995353",
"title": "A Phase 3, Multi-Center Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Risankizumab With Open-Label Induction, Randomized Double-Blind Maintenance, and Long-Term Extension Periods in Pediatric Subjects (2 to < 18 Years of Age) With Moderately to Severely Active Crohn's Disease",
"has_exemption": false,
"start_date": "2023-12-11",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06372145",
"publication_url": "https://clinicaltrials.gov/study/NCT06372145",
"title": "An Interventional, Phase 3 Extension Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Relapsing Multiple Sclerosis, Primary Progressive Multiple Sclerosis, or Nonrelapsing Secondary Progressive Multiple Sclerosis",
"has_exemption": false,
"start_date": "2024-04-16",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06194799",
"publication_url": "https://clinicaltrials.gov/study/NCT06194799",
"title": "A 52-Week, Open-Label Extension Study of ACP-204 in Adults With Alzheimer's Disease Psychosis",
"has_exemption": false,
"start_date": "2024-04-23",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "ACADIA Pharmaceuticals Inc.",
"sponsor_slug": "acadia-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06029270",
"publication_url": "https://clinicaltrials.gov/study/NCT06029270",
"title": "A Randomized Phase II Study of Nivolumab Versus Nivolumab and BMS-986016 (Relatlimab) as Maintenance Treatment After First-Line Treatment With Platinum-Gemcitabine-Nivolumab for Patients With Epstein-Barr Virus-Associated Recurrent/Metastatic Nasopharyngeal Carcinoma (REMAIN)",
"has_exemption": false,
"start_date": "2024-07-15",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06512064",
"publication_url": "https://clinicaltrials.gov/study/NCT06512064",
"title": "Advancing Telemedicine in Pulmonology: Acoustic-waveform Respiratory Evaluation (AWARE) Via Sensing and Machine Learning on Smartphones",
"has_exemption": false,
"start_date": "2024-07-23",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05563766",
"publication_url": "https://clinicaltrials.gov/study/NCT05563766",
"title": "A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer",
"has_exemption": false,
"start_date": "2024-10-01",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06653153",
"publication_url": "https://clinicaltrials.gov/study/NCT06653153",
"title": "A Study of Remternetug Versus Placebo in Early Alzheimer's Disease Participants at Risk for Cognitive and Functional Decline",
"has_exemption": false,
"start_date": "2024-10-24",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06246799",
"publication_url": "https://clinicaltrials.gov/study/NCT06246799",
"title": "Comparative Effectiveness of Two Initial Combination Therapies in Patients With New Onset Diabetes",
"has_exemption": false,
"start_date": "2024-11-07",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center at San Antonio",
"sponsor_slug": "the-university-of-texas-health-science-center-at-san-antonio",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06556563",
"publication_url": "https://clinicaltrials.gov/study/NCT06556563",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Optune® (TTFields, 200 kHz) Concomitant With Maintenance Temozolomide and Pembrolizumab Versus Optune® Concomitant With Maintenance Temozolomide and Placebo for the Treatment of Newly Diagnosed Glioblastoma (EF-41/KEYNOTE D58).",
"has_exemption": false,
"start_date": "2025-02-03",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "NovoCure GmbH",
"sponsor_slug": "novocure-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06932289",
"publication_url": "https://clinicaltrials.gov/study/NCT06932289",
"title": "Integrating Metabolic and Vascular Sensors to Monitor Cardiometabolic Disorders After Nutrition Interventions",
"has_exemption": false,
"start_date": "2025-05-01",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Greater Los Angeles Healthcare System",
"sponsor_slug": "va-greater-los-angeles-healthcare-system",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06754046",
"publication_url": "https://clinicaltrials.gov/study/NCT06754046",
"title": "BELIEVE Trial: Bulking vErsus sLing for Treating Stress Urinary IncontinEnce at the Time of Vaginal prolapsE Repair",
"has_exemption": false,
"start_date": "2025-05-01",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University Hospitals Cleveland Medical Center",
"sponsor_slug": "university-hospitals-cleveland-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06947083",
"publication_url": "https://clinicaltrials.gov/study/NCT06947083",
"title": "Phase II Study of Elranatamab as Maintenance Therapy Post Ciltacabtagene-autoleucel(Cilta-cel) in Patients With Clinical High Risk Relapsed Myeloma",
"has_exemption": false,
"start_date": "2025-05-27",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07033494",
"publication_url": "https://clinicaltrials.gov/study/NCT07033494",
"title": "A Phase 2 Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study to Evaluate the Efficacy and Safety of MK-2214 in Participants With Early Alzheimer's Disease",
"has_exemption": false,
"start_date": "2025-07-16",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06825390",
"publication_url": "https://clinicaltrials.gov/study/NCT06825390",
"title": "Mechanistic Clinical Trial of Auricular Stimulation and Cryogenic Auriculotherapy in Patients With Chronic Low-back Pain, Using Functional Near-infrared Spectroscopy and Magnetic Resonance Imaging",
"has_exemption": false,
"start_date": "2025-07-30",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Keith M Vogt",
"sponsor_slug": "keith-m-vogt",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07131475",
"publication_url": "https://clinicaltrials.gov/study/NCT07131475",
"title": "ReBlast Precision (Precision Biomarkers to Detect Brain Injury in Active-Duty United States Special Operations Forces With Repeated Blast Exposure)",
"has_exemption": false,
"start_date": "2025-10-14",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07210255",
"publication_url": "https://clinicaltrials.gov/study/NCT07210255",
"title": "A Randomized Controlled Multi-site Trial Evaluating SAINT for Postpartum Depression",
"has_exemption": false,
"start_date": "2025-11-01",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Magnus Medical",
"sponsor_slug": "magnus-medical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07298993",
"publication_url": "https://clinicaltrials.gov/study/NCT07298993",
"title": "Determining Evidence in a Placebo-Controlled, Randomized Experiment Studying Continuation vs. Removal of Inessential Beta-Blockers in Elders With Heart Failure With Preserved Ejection Fraction (DEPRESCRIBE-HFpEF)",
"has_exemption": false,
"start_date": "2026-02-02",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03176186",
"publication_url": "https://clinicaltrials.gov/study/NCT03176186",
"title": "XePOHCAS - Xenon by Inhalation for Post Out of Hospital Cardiac Arrest Syndrome",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Invero Pharma, Inc.",
"sponsor_slug": "invero-pharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07422480",
"publication_url": "https://clinicaltrials.gov/study/NCT07422480",
"title": "A Phase 3, Multicenter, Open-Label, Randomized Trial to Compare the Efficacy and Safety of Elritercept Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes in ESA-naïve Adult Participants Who Require Red Blood Cell Transfusions",
"has_exemption": false,
"start_date": "2026-04-01",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07274527",
"publication_url": "https://clinicaltrials.gov/study/NCT07274527",
"title": "The PEARL Trial: A Randomized Trial of Amnioinfusion's Protective Effects on Respiratory and Longitudinal Pediatric Outcomes After Intrapartum Thick Meconium Exposure",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07424092",
"publication_url": "https://clinicaltrials.gov/study/NCT07424092",
"title": "Intratumoral DNX-2401 Administration for Recurrent and Refractory High Grade Brain Tumors in Pediatric and Young Adult Patients",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Clinica Universidad de Navarra, Universidad de Navarra",
"sponsor_slug": "clinica-universidad-de-navarra-universidad-de-navarra",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06835504",
"publication_url": "https://clinicaltrials.gov/study/NCT06835504",
"title": "Efficacy of Intravenous Sub-Dissociative Ketamine Versus Intravenous Morphine in Children With Acute Pain",
"has_exemption": false,
"start_date": "2026-05-01",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Columbia University",
"sponsor_slug": "columbia-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07344168",
"publication_url": "https://clinicaltrials.gov/study/NCT07344168",
"title": "A Prospective, Open-label, Single Arm Study to Evaluate the Safety and Effectiveness of the EndoArt® in Subjects With Chronic Corneal Edema in Whom Multiple Prior Keratoplasty (EK/PK) Have Failed, and Who Are Not Reasonable Candidates for Any Form of Corneal Transplant, Including Penetrating Keratoplasty",
"has_exemption": false,
"start_date": "2026-05-01",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Eye-yon Medical",
"sponsor_slug": "eye-yon-medical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07153055",
"publication_url": "https://clinicaltrials.gov/study/NCT07153055",
"title": "Phase I/II Trial of Lurbinectedin With Osimertinib in Transformed Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2026-05-31",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Misty Shields",
"sponsor_slug": "misty-shields",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03520751",
"publication_url": "https://clinicaltrials.gov/study/NCT03520751",
"title": "Phase I/IIa Trial Evaluating scAAV1.tMCK.NTF3 for Treatment of Charcot-Marie-Tooth Neuropathy Type 1A (CMT1A)",
"has_exemption": false,
"start_date": "2027-04-30",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Nationwide Children's Hospital",
"sponsor_slug": "nationwide-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05556902",
"publication_url": "https://clinicaltrials.gov/study/NCT05556902",
"title": "Therapeutic Mechanisms of Epidural Spinal Cord Stimulation",
"has_exemption": false,
"start_date": "2022-08-02",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06345963",
"publication_url": "https://clinicaltrials.gov/study/NCT06345963",
"title": "Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 1)",
"has_exemption": false,
"start_date": "2024-05-21",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06327100",
"publication_url": "https://clinicaltrials.gov/study/NCT06327100",
"title": "Open Label Phase 1/2 Study of Tasquinimod in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (Post-PV MF), or Post-Essential Thrombocytosis Myelofibrosis (Post-ET MF)",
"has_exemption": false,
"start_date": "2024-08-01",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06494111",
"publication_url": "https://clinicaltrials.gov/study/NCT06494111",
"title": "Systemic Therapy of Open-label Prophylactic Pravastatin or Pentoxifylline/Tocopherol Prevention of Lymphedema Advancing to Eventual Fibrosis: an Interventional Registry-embedded Bayesian Randomized Trial for Radiation Sequelae (STOP4-LATE-FIBROSE)",
"has_exemption": false,
"start_date": "2025-02-13",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06897930",
"publication_url": "https://clinicaltrials.gov/study/NCT06897930",
"title": "A Phase 1b/2 Study of AZD0120, a Chimeric Antigen Receptor T-cell (CAR T) Therapy Targeting CD19 and B-cell Maturation Antigen (BCMA) in Subjects With Refractory Systemic Lupus Erythematosus (SLE)",
"has_exemption": false,
"start_date": "2025-04-21",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06909110",
"publication_url": "https://clinicaltrials.gov/study/NCT06909110",
"title": "Viral Specific T-Lymphocytes by Cytokine Capture System (CCS) to Treat Infection With Adenovirus, Cytomegalovirus or Epstein-Barr Virus After Hematopoietic Cell Transplantation or Solid Organ Transplantation and in Patients With Compromised Immunity",
"has_exemption": false,
"start_date": "2025-04-30",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Jessie L. Alexander",
"sponsor_slug": "jessie-l-alexander",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06261840",
"publication_url": "https://clinicaltrials.gov/study/NCT06261840",
"title": "Refining Treatment Options for Trichomonas Vaginalis Infection in Women and Men: A Comparative Analysis of Oral Multi-Dose Metronidazole and Single-Dose Secnidazole",
"has_exemption": false,
"start_date": "2025-05-06",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Tulane University",
"sponsor_slug": "tulane-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06961916",
"publication_url": "https://clinicaltrials.gov/study/NCT06961916",
"title": "Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 2)",
"has_exemption": false,
"start_date": "2025-06-03",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06999577",
"publication_url": "https://clinicaltrials.gov/study/NCT06999577",
"title": "The MVP Trial: A Randomized Controlled Trial of Mechanism Guided vs PPI Strategy for Laryngopharyngeal Reflux",
"has_exemption": false,
"start_date": "2025-06-04",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06501820",
"publication_url": "https://clinicaltrials.gov/study/NCT06501820",
"title": "Neural Control of Gait & Navigation in ADRD, Aim 3 Clinical Trial",
"has_exemption": false,
"start_date": "2025-11-13",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Florida",
"sponsor_slug": "university-of-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07024706",
"publication_url": "https://clinicaltrials.gov/study/NCT07024706",
"title": "The MAVRiC Study: A Phase II Study of Disease Risk Mutation Guided Finite Duration Acalabrutinib Plus Venetoclax for Relapse in CLL/SLL After First-line Finite Covalent BTKi Plus BCL2i Combination, With or Without Obinutuzumab",
"has_exemption": false,
"start_date": "2026-01-30",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06782542",
"publication_url": "https://clinicaltrials.gov/study/NCT06782542",
"title": "Single-Arm Phase 2 Study of Olutasidenib, Venetoclax, and Azacitidine in IDH1 Mutated Newly Diagnosed Acute Myeloid Leukemia Patients Who Are Eligible for Intensive Induction Chemotherapy",
"has_exemption": false,
"start_date": "2026-05-01",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Justin Watts, MD",
"sponsor_slug": "justin-watts-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07197866",
"publication_url": "https://clinicaltrials.gov/study/NCT07197866",
"title": "An Open-Label Extension, Multi-Centered, Phase 2 Trial to Describe the Safety and Efficacy of TEV-56286 (Emrusolmin) in Participants With Multiple System Atrophy",
"has_exemption": false,
"start_date": "2025-09-30",
"completion_date": "2029-05-03",
"has_results": false,
"results_due": false,
"sponsor_name": "Teva Branded Pharmaceutical Products R&D LLC",
"sponsor_slug": "teva-branded-pharmaceutical-products-rd-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07076121",
"publication_url": "https://clinicaltrials.gov/study/NCT07076121",
"title": "A Randomized, Phase 2/3 Study Comparing BMS-986504 in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma Harboring Homozygous MTAP Deletion",
"has_exemption": false,
"start_date": "2025-10-23",
"completion_date": "2029-05-03",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07318610",
"publication_url": "https://clinicaltrials.gov/study/NCT07318610",
"title": "A Master Protocol for a Phase 3, Multicenter, Randomized Study to Evaluate the Efficacy and Safety of REGN7508 and REGN9933, Monoclonal Antibodies Against Factor XI, in Participants With Recent Lower Extremity Revascularization for Symptomatic Peripheral Artery Disease (ROXI-PALISADE)",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-05-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06976476",
"publication_url": "https://clinicaltrials.gov/study/NCT06976476",
"title": "Prospective Randomized Phase II Study Evaluating Efficacy and Safety of IgPro20 as Infection Prophylaxis in Patients With Multiple Myeloma and Hypogammaglobulinemia Receiving Therapy With a Bispecific Monoclonal Antibody (BsAbs)",
"has_exemption": false,
"start_date": "2025-05-08",
"completion_date": "2029-05-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06627647",
"publication_url": "https://clinicaltrials.gov/study/NCT06627647",
"title": "A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab in Combination With Platinum-based Chemotherapy for the First-line Treatment of Patients With Metastatic Non-squamous Non-small Cell Lung Cancer Whose Tumors Express PD-L1 (ARTEMIDE-Lung03)",
"has_exemption": false,
"start_date": "2024-11-27",
"completion_date": "2029-05-10",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06630416",
"publication_url": "https://clinicaltrials.gov/study/NCT06630416",
"title": "A Phase II Trial to Evaluate Pemetrexed Response in Relation to Tumor Alterations of Gene Status in Patients With Previously Treated Metastatic Urothelial Carcinoma and Other Solid Tumors",
"has_exemption": false,
"start_date": "2024-11-27",
"completion_date": "2029-05-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07252232",
"publication_url": "https://clinicaltrials.gov/study/NCT07252232",
"title": "RASolute 304: A Phase 3 Multicenter, Open-label, Randomized, 2-Arm Study of Adjuvant Daraxonrasib Versus Standard of Care Observation Following Completion of Neoadjuvant and/or Adjuvant Chemotherapy in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)",
"has_exemption": false,
"start_date": "2025-12-15",
"completion_date": "2029-05-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Revolution Medicines, Inc.",
"sponsor_slug": "revolution-medicines-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05555732",
"publication_url": "https://clinicaltrials.gov/study/NCT05555732",
"title": "A Randomized Phase 3 Study of Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in Subjects With No Prior Therapy for Advanced or Metastatic PD-L1 TPS <50% Non-squamous Non-small Cell Lung Cancer Without Actionable Genomic Alterations (TROPION-Lung07)",
"has_exemption": false,
"start_date": "2023-01-11",
"completion_date": "2029-05-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Daiichi Sankyo",
"sponsor_slug": "daiichi-sankyo",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07184931",
"publication_url": "https://clinicaltrials.gov/study/NCT07184931",
"title": "A Multicenter, Multinational, Randomized, Double-blind, Placebo-controlled Phase 3, Induction Study to Evaluate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease",
"has_exemption": false,
"start_date": "2025-10-01",
"completion_date": "2029-05-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07201922",
"publication_url": "https://clinicaltrials.gov/study/NCT07201922",
"title": "A Double Blind, Randomized, Placebo-controlled Exploratory Trial to Investigate the Efficacy and Safety of Nerandomilast Over 24 Months When Administered in Individuals With Interstitial Lung Abnormalities and a Family History of Pulmonary Fibrosis to Reduce the Risk of Worsening (DROP-FPF)",
"has_exemption": false,
"start_date": "2026-02-10",
"completion_date": "2029-05-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Boehringer Ingelheim",
"sponsor_slug": "boehringer-ingelheim",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05564390",
"publication_url": "https://clinicaltrials.gov/study/NCT05564390",
"title": "Master Screening and Reassessment Protocol (MSRP) for the NCI MyeloMATCH Clinical Trials",
"has_exemption": false,
"start_date": "2024-06-18",
"completion_date": "2029-05-15",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06317649",
"publication_url": "https://clinicaltrials.gov/study/NCT06317649",
"title": "A Randomized Phase II Study of Venetoclax and HMA-Based Therapies for the Treatment of Older and Unfit Adults With Newly Diagnosed FLT3-Mutated Acute Myeloid Leukemia (AML): A MyeloMATCH Treatment Trial",
"has_exemption": false,
"start_date": "2024-09-27",
"completion_date": "2029-05-15",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05458297",
"publication_url": "https://clinicaltrials.gov/study/NCT05458297",
"title": "A Multicenter, Open-label, Phase 2 Basket Study to Evaluate the Safety and Efficacy of MK-2140 as a Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (waveLINE-006)",
"has_exemption": false,
"start_date": "2022-07-21",
"completion_date": "2029-05-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05878717",
"publication_url": "https://clinicaltrials.gov/study/NCT05878717",
"title": "A Phase 2/3, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate The Efficacy And Safety of Belimumab Administered Subcutaneously in Adults With Systemic Sclerosis Associated Interstitial Lung Disease (SSC-ILD)",
"has_exemption": false,
"start_date": "2023-09-13",
"completion_date": "2029-05-17",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06662448",
"publication_url": "https://clinicaltrials.gov/study/NCT06662448",
"title": "An Open-Label Study to Evaluate the Efficacy and Feasibility of Home-Based Repetitive Transorbital Alternating Current Stimulation for Optic Neuropathies",
"has_exemption": false,
"start_date": "2024-11-18",
"completion_date": "2029-05-18",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06430788",
"publication_url": "https://clinicaltrials.gov/study/NCT06430788",
"title": "Phase 2a/2b Study Emapalumab: A Window of Opportunity in Pediatric Aplastic Anemia",
"has_exemption": false,
"start_date": "2024-05-21",
"completion_date": "2029-05-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07006506",
"publication_url": "https://clinicaltrials.gov/study/NCT07006506",
"title": "Phase II Open Label Prospective Nonrandomized Trial of Belumosudil for Switch-Maintenance Prophylaxis of Graft-versus-Host Disease in Allogeneic Hematopoietic Cell Transplantation",
"has_exemption": false,
"start_date": "2025-05-21",
"completion_date": "2029-05-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06667076",
"publication_url": "https://clinicaltrials.gov/study/NCT06667076",
"title": "A Phase 2b, Open-Label, Two-cohort Study of Subcutaneous Amivantamab in Combination With Lazertinib as First-Line Treatment, or Subcutaneous Amivantamab in Combination With Platinum-Based Chemotherapy as Second-line Treatment, for Common EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2024-12-16",
"completion_date": "2029-05-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07203001",
"publication_url": "https://clinicaltrials.gov/study/NCT07203001",
"title": "An Open-label Phase II Trial to Evaluate the Clinical Efficacy, Safety and Tolerability of MAS825 in Pediatric and Adult Participants With Still's Disease",
"has_exemption": false,
"start_date": "2025-11-03",
"completion_date": "2029-05-24",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07332481",
"publication_url": "https://clinicaltrials.gov/study/NCT07332481",
"title": "A Phase 3, Randomized, Double-Blind,Placebo-Controlled Parallel Study to Evaluate the Efficacy and Safety of Enpatoran in Participants With Active Cutaneous Manifestations of Lupus Erythematosus With or Without Systemic Disease Receiving Standard of Care (ELOWEN-1)",
"has_exemption": false,
"start_date": "2026-03-27",
"completion_date": "2029-05-24",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany",
"sponsor_slug": "merck-healthcare-kgaa-darmstadt-germany-an-affiliate-of-merck-kgaa-darmstadt-germany",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03965234",
"publication_url": "https://clinicaltrials.gov/study/NCT03965234",
"title": "Phase I/ II Study of Pulmonary Suffusion to Control Minimal Residual Disease in Resectable or Ablatable Sarcoma or Colorectal Pulmonary Metastases",
"has_exemption": false,
"start_date": "2020-07-16",
"completion_date": "2029-05-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Roswell Park Cancer Institute",
"sponsor_slug": "roswell-park-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05285826",
"publication_url": "https://clinicaltrials.gov/study/NCT05285826",
"title": "A Phase 3 Randomized, Double-Blind, Placebo-Controlled Clinical Study to Evaluate the Efficacy, Immunogenicity, and Safety of V503, a 9-Valent Human Papillomavirus (HPV) Vaccine, in Chinese Males 20 to 45 Years of Age",
"has_exemption": false,
"start_date": "2022-02-18",
"completion_date": "2029-05-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07287982",
"publication_url": "https://clinicaltrials.gov/study/NCT07287982",
"title": "A Phase 2 Double-Blinded, Randomized, Placebo-Controlled Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy",
"has_exemption": false,
"start_date": "2025-12-19",
"completion_date": "2029-05-28",
"has_results": false,
"results_due": false,
"sponsor_name": "argenx",
"sponsor_slug": "argenx",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03307980",
"publication_url": "https://clinicaltrials.gov/study/NCT03307980",
"title": "A FACTOR IX (FIX) GENE TRANSFER, MULTI CENTER EVALUATION OF THE LONG TERM SAFETY AND EFFICACY STUDY OF PF 06838435 AND A DOSE ESCALATION SUBSTUDY IN INDIVIDUALS WITH HEMOPHILIA B",
"has_exemption": false,
"start_date": "2017-06-22",
"completion_date": "2029-05-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04776252",
"publication_url": "https://clinicaltrials.gov/study/NCT04776252",
"title": "A Phase 3 Open-label Rollover Clinical Study of Doravirine/Islatravir (DOR/ISL) Once-daily for the Treatment of HIV-1 Infection in Participants Who Previously Received DOR/ISL in a Phase 2 or Phase 3 DOR/ISL Clinical Study",
"has_exemption": false,
"start_date": "2021-09-15",
"completion_date": "2029-05-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04802759",
"publication_url": "https://clinicaltrials.gov/study/NCT04802759",
"title": "A Phase Ib/II, Open-Label, Multicenter, Randomized Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Breast Cancer (MORPHEUS-BREAST CANCER)",
"has_exemption": false,
"start_date": "2021-06-22",
"completion_date": "2029-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04669171",
"publication_url": "https://clinicaltrials.gov/study/NCT04669171",
"title": "A Global Multicenter Phase 1/2 Trial of EO2463, a Novel Microbial-Derived Peptide Therapeutic Vaccine, as Monotherapy, and in Combination With Lenalidomide and Rituximab, for Treatment of Patients With Indolent Non-Hodgkin's Lymphoma",
"has_exemption": false,
"start_date": "2021-07-05",
"completion_date": "2029-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Enterome",
"sponsor_slug": "enterome",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06319248",
"publication_url": "https://clinicaltrials.gov/study/NCT06319248",
"title": "MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) Trial",
"has_exemption": false,
"start_date": "2024-05-14",
"completion_date": "2029-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06599099",
"publication_url": "https://clinicaltrials.gov/study/NCT06599099",
"title": "Building Mood State Classifiers to Inform Deep Brain Stimulation of Treatment-Resistant Bipolar Depression",
"has_exemption": false,
"start_date": "2025-01-01",
"completion_date": "2029-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Wayne Goodman MD",
"sponsor_slug": "wayne-goodman-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03705585",
"publication_url": "https://clinicaltrials.gov/study/NCT03705585",
"title": "CVD 38000: Immunity, Microbiome, Epigenetics, and a Systems Biology Approach to the Study of Responses to Vaccination With Typhoid and/or Cholera",
"has_exemption": false,
"start_date": "2018-11-05",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Maryland, Baltimore",
"sponsor_slug": "university-of-maryland-baltimore",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04339764",
"publication_url": "https://clinicaltrials.gov/study/NCT04339764",
"title": "A Phase I/IIa Trial for Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration",
"has_exemption": false,
"start_date": "2020-09-23",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Eye Institute (NEI)",
"sponsor_slug": "national-eye-institute-nei",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05318573",
"publication_url": "https://clinicaltrials.gov/study/NCT05318573",
"title": "A Phase 2a Study With Safety Run-in to Evaluate the Safety, Tolerability, and Preliminary Efficacy of FF-10832 Monotherapy or in Combination With Pembrolizumab in Patients With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2022-06-01",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Fujifilm Pharmaceuticals U.S.A., Inc.",
"sponsor_slug": "fujifilm-pharmaceuticals-usa-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06016842",
"publication_url": "https://clinicaltrials.gov/study/NCT06016842",
"title": "A Phase III Randomised, Parallel-Group, Double-Blind, Placebo-Controlled, Two-Arm Study to Evaluate the Efficacy and Safety of Elafibranor 80 mg on Long-Term Clinical Outcomes in Adult Participants With Primary Biliary Cholangitis (PBC)",
"has_exemption": false,
"start_date": "2023-08-31",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ipsen",
"sponsor_slug": "ipsen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05537220",
"publication_url": "https://clinicaltrials.gov/study/NCT05537220",
"title": "NAC Attack, A Phase III, Multicenter, Randomized, Parallel, Double Masked, Placebo-Controlled Study Evaluating the Efficacy and Safety of Oral N-Acetylcysteine in Patients With Retinitis Pigmentosa",
"has_exemption": false,
"start_date": "2023-10-11",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06420297",
"publication_url": "https://clinicaltrials.gov/study/NCT06420297",
"title": "A Long-term, Open-label Extension Study of Carbetocin Nasal Spray for the Treatment of Hyperphagia in Prader-Willi Syndrome",
"has_exemption": false,
"start_date": "2024-03-11",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ACADIA Pharmaceuticals Inc.",
"sponsor_slug": "acadia-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05940207",
"publication_url": "https://clinicaltrials.gov/study/NCT05940207",
"title": "Safety Testing of Hydrogen Peroxide-Generating e-Bandage on Normal Human Skin",
"has_exemption": false,
"start_date": "2024-03-27",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06545136",
"publication_url": "https://clinicaltrials.gov/study/NCT06545136",
"title": "A Multicenter, Long-term, Follow-up Study to Investigate the Safety and Durability of Response Following Dosing of an Adeno-associated Viral Vector (FLT201) in Subjects With Gaucher Disease (GALILEO-2)",
"has_exemption": false,
"start_date": "2024-05-13",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Spur Therapeutics",
"sponsor_slug": "spur-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06295731",
"publication_url": "https://clinicaltrials.gov/study/NCT06295731",
"title": "A Phase 2/3, Randomized Study of INBRX-106 Combined With Pembrolizumab Versus Pembrolizumab as First Line Treatment for Patients With Recurrent or Metastatic (R/M) Head and Neck Squamous Cell Carcinoma (HNSCC) Expressing PD-L1 (CPS ≥20) (HexAgon-HN)",
"has_exemption": false,
"start_date": "2024-05-14",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Inhibrx Biosciences, Inc",
"sponsor_slug": "inhibrx-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06378866",
"publication_url": "https://clinicaltrials.gov/study/NCT06378866",
"title": "MC230502 Dynamic Investigator Initiated Enterprise (DIVINE) in Prostate Cancer",
"has_exemption": false,
"start_date": "2024-06-03",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06374875",
"publication_url": "https://clinicaltrials.gov/study/NCT06374875",
"title": "A Prospective Multicenter International Randomized Controlled Trial Comparing Surgical and Medical Therapies in the Treatment of Advanced Metabolic Dysfunction Associated Steatohepatitis",
"has_exemption": false,
"start_date": "2024-07-11",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ali Aminian",
"sponsor_slug": "ali-aminian",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06485206",
"publication_url": "https://clinicaltrials.gov/study/NCT06485206",
"title": "A Clinical Investigation Evaluating Safety and Effectiveness of Primary Hybrid Construct of Mobi-C and ACDF in the Treatment of Two-level Symptomatic Degenerative Disc Disease in the Cervical Spine.",
"has_exemption": false,
"start_date": "2024-09-01",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Highridge Medical",
"sponsor_slug": "highridge-medical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06789848",
"publication_url": "https://clinicaltrials.gov/study/NCT06789848",
"title": "Phase II Basket Trial of Ligufalimab (AK117) and Cadonilimab (AK104) in Advanced Hepatobiliary Cancers",
"has_exemption": false,
"start_date": "2025-02-18",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06682442",
"publication_url": "https://clinicaltrials.gov/study/NCT06682442",
"title": "Induction Chemotherapy Response-Guided Radiation for EBV-Associated Nasopharyngeal Carcinoma",
"has_exemption": false,
"start_date": "2025-03-18",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06604520",
"publication_url": "https://clinicaltrials.gov/study/NCT06604520",
"title": "Functional Neuroimaging to Examine Affective Symptoms and Cognition in Frontotemporal Dementia",
"has_exemption": false,
"start_date": "2025-03-20",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06907290",
"publication_url": "https://clinicaltrials.gov/study/NCT06907290",
"title": "A Global, Randomized, Open-label, Multicenter, Phase 2b/3 Trial Evaluating BJT-778 vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (AZURE-1)",
"has_exemption": false,
"start_date": "2025-03-25",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mirum Pharmaceuticals, Inc.",
"sponsor_slug": "mirum-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06890598",
"publication_url": "https://clinicaltrials.gov/study/NCT06890598",
"title": "A Phase 3, Multicenter, Double-Blind, Placebo-controlled Study Assessing the Efficacy and Safety of Olomorasib in Combination With Standard of Care Immunotherapy in Participants With Resected or Unresectable KRAS G12C-Mutant, Non-Small Cell Lung Cancer - SUNRAY-02",
"has_exemption": false,
"start_date": "2025-03-27",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06966401",
"publication_url": "https://clinicaltrials.gov/study/NCT06966401",
"title": "A Long-Term, Open-Label Study to Assess the Safety and Tolerability of NBI-1065845 as Adjunctive Treatment in Subjects With Major Depressive Disorder (MDD)",
"has_exemption": false,
"start_date": "2025-04-16",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Neurocrine Biosciences",
"sponsor_slug": "neurocrine-biosciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06768905",
"publication_url": "https://clinicaltrials.gov/study/NCT06768905",
"title": "IOMAB-ACT: A Phase Ib/II Multi-institutional Study of 131 I-Apamistamab Followed by CD19-Targeted CAR-T Cell Therapy for Patients With Relapsed or Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL)",
"has_exemption": false,
"start_date": "2025-04-25",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06812715",
"publication_url": "https://clinicaltrials.gov/study/NCT06812715",
"title": "Clonal Dynamics of Chronic Lymphocytic Leukaemia Treated With Pirtobrutinib After Previous Treatment With Zanubrutinib",
"has_exemption": false,
"start_date": "2025-05-05",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Peter MacCallum Cancer Centre, Australia",
"sponsor_slug": "peter-maccallum-cancer-centre-australia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06512194",
"publication_url": "https://clinicaltrials.gov/study/NCT06512194",
"title": "An Investigation of Strategies to Understand and Optimize the Antidepressant Effects of Psilocybin (The OPTIMIZE Study)",
"has_exemption": false,
"start_date": "2025-05-13",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Charles Raison",
"sponsor_slug": "charles-raison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06716112",
"publication_url": "https://clinicaltrials.gov/study/NCT06716112",
"title": "Mechanisms of Paired Vagus Nerve Stimulation (VNS) in Chronic Stroke: a Randomized, Blinded, Sham-controlled, Single-center Mechanistic Trial",
"has_exemption": false,
"start_date": "2025-07-15",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06349083",
"publication_url": "https://clinicaltrials.gov/study/NCT06349083",
"title": "Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2025-08-26",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06899165",
"publication_url": "https://clinicaltrials.gov/study/NCT06899165",
"title": "Processing Intergenerational Trauma With Psilocybin-Assisted Therapy",
"has_exemption": false,
"start_date": "2025-08-28",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Rachel Yehuda",
"sponsor_slug": "rachel-yehuda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07174583",
"publication_url": "https://clinicaltrials.gov/study/NCT07174583",
"title": "A Multicenter Study Evaluating the Safety, Efficacy, and Pharmacokinetics of IDE849 in Patients With DLL3-Expressing Tumors Including Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2025-10-14",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "IDEAYA Biosciences",
"sponsor_slug": "ideaya-biosciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07218796",
"publication_url": "https://clinicaltrials.gov/study/NCT07218796",
"title": "A Prospective, Multicenter, Randomized, Masked, Controlled Study to Evaluate the Safety and Efficacy of the Bimatoprost Implant System (78 mcg) Used in Combination With the SpyGlass IOL Compared to Timolol Maleate Ophthalmic Solution, USP, 0.5%,",
"has_exemption": false,
"start_date": "2025-10-28",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "SpyGlass Pharma, Inc.",
"sponsor_slug": "spyglass-pharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07155174",
"publication_url": "https://clinicaltrials.gov/study/NCT07155174",
"title": "A Phase 2 Randomized, Open Label, Multicenter Study to Evaluate the Optimal Dose, Safety, and Efficacy of ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Subjects With Previously Untreated Extensive Stage Small Cell Lung Cancer (ES-SCLC)",
"has_exemption": false,
"start_date": "2025-11-25",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07174336",
"publication_url": "https://clinicaltrials.gov/study/NCT07174336",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of LY4064809 Combined With a CDK4/6 Inhibitor and Endocrine Therapy in Adults With HR+, HER2-Advanced Breast Cancer With a PIK3CA Mutation Who Received No Prior Treatment for Advanced Breast Cancer (PIKALO-2)",
"has_exemption": false,
"start_date": "2025-12-22",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06961357",
"publication_url": "https://clinicaltrials.gov/study/NCT06961357",
"title": "Phase I/II Clinical Trial of CD40L-augmented Tumor Infiltrating Lymphocytes (TIL) for Patients With Advanced Melanoma",
"has_exemption": false,
"start_date": "2026-01-01",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07285694",
"publication_url": "https://clinicaltrials.gov/study/NCT07285694",
"title": "An Open-label, Multicenter Phase 1/2 Study to Evaluate the Safety and Efficacy of AB-3028 in Patients With Castration Resistant Prostate Cancer (CRPC)",
"has_exemption": false,
"start_date": "2026-01-09",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Arsenal Biosciences, Inc.",
"sponsor_slug": "arsenal-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06954129",
"publication_url": "https://clinicaltrials.gov/study/NCT06954129",
"title": "Markers of Nephrotoxicity During Treatment With Antibiotic Combinations: A Pragmatic Clinical Trial",
"has_exemption": false,
"start_date": "2026-01-28",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06875128",
"publication_url": "https://clinicaltrials.gov/study/NCT06875128",
"title": "An Open-label, Randomized, Multi-Center Study to Evaluate the Efficacy and Safety of Induction Treatment With Melphalan/HDS Followed by Consolidation Treatment With Eribulin or Vinorelbine or Capecitabine Versus Eribulin or Vinorelbine or Capecitabine Alone in Patients With Metastatic Breast Cancer With Liver Dominant Disease",
"has_exemption": false,
"start_date": "2026-01-29",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Delcath Systems Inc.",
"sponsor_slug": "delcath-systems-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07397338",
"publication_url": "https://clinicaltrials.gov/study/NCT07397338",
"title": "A Phase 1/2 Open-Label, Multicenter Study of RAS(ON) Inhibitors in Combination With Ivonescimab With or Without Other Anti-Cancer Agents in Patients With Solid Tumors",
"has_exemption": false,
"start_date": "2026-01-30",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Revolution Medicines, Inc.",
"sponsor_slug": "revolution-medicines-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07436156",
"publication_url": "https://clinicaltrials.gov/study/NCT07436156",
"title": "SUMMIT RISE Study of Acute Ischemic Stroke Patients Evaluating the Route 92 Medical Reperfusion Systems.",
"has_exemption": false,
"start_date": "2026-02-12",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Route 92 Medical, Inc.",
"sponsor_slug": "route-92-medical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07071935",
"publication_url": "https://clinicaltrials.gov/study/NCT07071935",
"title": "A Pilot Randomized Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06773936",
"publication_url": "https://clinicaltrials.gov/study/NCT06773936",
"title": "A Phase II Trial of Asciminib, Dasatinib, Prednisone, and Blinatumomab for Participants With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia",
"has_exemption": false,
"start_date": "2026-05-15",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "SWOG Cancer Research Network",
"sponsor_slug": "swog-cancer-research-network",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07472439",
"publication_url": "https://clinicaltrials.gov/study/NCT07472439",
"title": "Randomized Controlled Trial of the Auryon Atherectomy System Used in Combination With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone Treating Infrapopliteal Lesions in Subjects With Critical Limb Ischemia",
"has_exemption": false,
"start_date": "2026-05-31",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Angiodynamics, Inc.",
"sponsor_slug": "angiodynamics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
}
]
}