HTTP 200 OK
Allow: GET, POST, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"recordsFiltered": 50704,
"recordsTotal": 50704,
"next": "http://fdaaa.trialstracker.net/api/trials/?format=api&length=300&start=49500",
"previous": "http://fdaaa.trialstracker.net/api/trials/?format=api&length=300&start=48900",
"results": [
{
"registry_id": "NCT06899126",
"publication_url": "https://clinicaltrials.gov/study/NCT06899126",
"title": "A Phase 3, Multicenter, Randomized, Open-label Trial of Trastuzumab Deruxtecan in Combination With Pembrolizumab Versus Platinum-based Chemotherapy in Combination With Pembrolizumab, as First-line Therapy in Participants With Locally Advanced Unresectable or Metastatic HER2 Overexpressing and PD-L1 TPS <50% Non-squamous Non-small Cell Lung Cancer (DESTINY-Lung06)",
"has_exemption": false,
"start_date": "2025-10-24",
"completion_date": "2030-04-24",
"has_results": false,
"results_due": false,
"sponsor_name": "Daiichi Sankyo",
"sponsor_slug": "daiichi-sankyo",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07707895",
"publication_url": "https://clinicaltrials.gov/study/NCT07707895",
"title": "A Phase Ib/II, Open-label, Safety and Tolerability Trial of Obrixtamig in Combination With ZL-1310 in Patients With Poorly Differentiated NEC",
"has_exemption": false,
"start_date": "2026-10-19",
"completion_date": "2030-04-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Boehringer Ingelheim",
"sponsor_slug": "boehringer-ingelheim",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07153497",
"publication_url": "https://clinicaltrials.gov/study/NCT07153497",
"title": "A Randomized Phase 2 Trial of Olutasidenib-Based Therapies in Patients With Newly Diagnosed IDH1-Mutant Myeloid Malignancies: A MyeloMATCH Substudy",
"has_exemption": false,
"start_date": "2026-11-27",
"completion_date": "2030-04-26",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07566377",
"publication_url": "https://clinicaltrials.gov/study/NCT07566377",
"title": "Cord Blood Transplantation in Children and Young Adults With Hematologic Malignancies",
"has_exemption": false,
"start_date": "2026-04-28",
"completion_date": "2030-04-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03547973",
"publication_url": "https://clinicaltrials.gov/study/NCT03547973",
"title": "A Phase II Open-Label Study of Sacituzumab Govitecan in Unresectable Locally Advanced/Metastatic Urothelial Cancer",
"has_exemption": false,
"start_date": "2018-08-13",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Gilead Sciences",
"sponsor_slug": "gilead-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04806854",
"publication_url": "https://clinicaltrials.gov/study/NCT04806854",
"title": "A Single-Center, Randomized, Open-Label, Parallel Arm Study of Daily Oral LUM-201 in Naive-to-Treatment, Prepubertal Children With Idiopathic Pediatric Growth Hormone Deficiency (PGHD)",
"has_exemption": false,
"start_date": "2021-07-14",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Lumos Pharma",
"sponsor_slug": "lumos-pharma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06012240",
"publication_url": "https://clinicaltrials.gov/study/NCT06012240",
"title": "A Phase 3 Randomized, Placebo-controlled, Double-blind Program to Evaluate Efficacy and Safety of Upadacitinib in Adult and Adolescent Subjects With Severe Alopecia Areata",
"has_exemption": false,
"start_date": "2023-10-11",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05919108",
"publication_url": "https://clinicaltrials.gov/study/NCT05919108",
"title": "Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers",
"has_exemption": false,
"start_date": "2024-06-11",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt-Ingram Cancer Center",
"sponsor_slug": "vanderbilt-ingram-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06322108",
"publication_url": "https://clinicaltrials.gov/study/NCT06322108",
"title": "Assessment of the Safety and Efficacy of Balstilimab in Combination With Botensilimab for the Treatment of Non-Small Cell Lung Cancer (IMMONC0008)",
"has_exemption": false,
"start_date": "2024-06-13",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Immune Oncology Research Institute",
"sponsor_slug": "immune-oncology-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06547216",
"publication_url": "https://clinicaltrials.gov/study/NCT06547216",
"title": "A Phase 2 Open-label Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of AOC 1020 Administered Intravenously to Participants With Facioscapulohumeral Muscular Dystrophy (FSHD)",
"has_exemption": false,
"start_date": "2024-07-25",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Avidity Biosciences, Inc.",
"sponsor_slug": "avidity-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06721689",
"publication_url": "https://clinicaltrials.gov/study/NCT06721689",
"title": "A Phase 1/2 Clinical Trial of the Novel Topoisomerase I Inhibitor PEEL-224 as a Single Agent and in Combination With Vincristine and Temozolomide in Children With Refractory, Progressive or Relapsed Solid Tumors",
"has_exemption": false,
"start_date": "2025-03-23",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Theodore Laetsch",
"sponsor_slug": "theodore-laetsch",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06861920",
"publication_url": "https://clinicaltrials.gov/study/NCT06861920",
"title": "Targeting Interindividual Variability in NSAID Responses to Mitigate Chronic Pelvic Pain Risk in Dysmenorrhea (NSAID HEAL)",
"has_exemption": false,
"start_date": "2025-04-07",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Endeavor Health",
"sponsor_slug": "endeavor-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06884423",
"publication_url": "https://clinicaltrials.gov/study/NCT06884423",
"title": "Infant Survival and Long-term Outcome Following Fetoscopic Endoluminal Tracheal Occlusion in Severe Left and Right Congenital Diaphragmatic Hernia, A Phase III Trial",
"has_exemption": false,
"start_date": "2025-04-07",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Holly L Hedrick, MD",
"sponsor_slug": "holly-l-hedrick-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06892678",
"publication_url": "https://clinicaltrials.gov/study/NCT06892678",
"title": "DFMO Maintenance for Patients With Relapsed/Refractory Ewing Sarcoma or Osteosarcoma",
"has_exemption": false,
"start_date": "2025-04-07",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Montefiore Medical Center",
"sponsor_slug": "montefiore-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06702033",
"publication_url": "https://clinicaltrials.gov/study/NCT06702033",
"title": "Phase II Trial of Surgery Followed by Risk-Directed Post-Operative Adjuvant Therapy for HPV-Related Oropharynx Squamous Cell Carcinoma: \"The Minimalist Trial-2 (MINT-2)\"",
"has_exemption": false,
"start_date": "2025-04-10",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06946576",
"publication_url": "https://clinicaltrials.gov/study/NCT06946576",
"title": "Infant Survival and Long-term Outcomes Following Fetoscopic Endoluminal Tracheal Occlusion in Severe Left and Right Congenital Diaphragmatic Hernia, A Phase III Trial",
"has_exemption": false,
"start_date": "2025-09-30",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Oregon Health and Science University",
"sponsor_slug": "oregon-health-and-science-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07231497",
"publication_url": "https://clinicaltrials.gov/study/NCT07231497",
"title": "Cognitive Strategies in Early Psychosis 1",
"has_exemption": false,
"start_date": "2025-10-31",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Minnesota",
"sponsor_slug": "university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07284589",
"publication_url": "https://clinicaltrials.gov/study/NCT07284589",
"title": "Evaluation of Ultralow Dose PET Imaging for Detecting SSTR2 Radiotracer Uptake",
"has_exemption": false,
"start_date": "2025-12-11",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Akiva Mintz",
"sponsor_slug": "akiva-mintz",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06666348",
"publication_url": "https://clinicaltrials.gov/study/NCT06666348",
"title": "A Phase 1/2 Study of Mirdametinib and Vinblastine for Newly Diagnosed or Previously Untreated Patients With Pediatric Low-grade Glioma and Activation of the MAPK Pathway",
"has_exemption": false,
"start_date": "2026-01-12",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "St. Justine's Hospital",
"sponsor_slug": "st-justines-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07469384",
"publication_url": "https://clinicaltrials.gov/study/NCT07469384",
"title": "Sensory Contributions to Third Visual Pathway Dysfunction in Schizophrenia: Correlation and Causation",
"has_exemption": false,
"start_date": "2026-02-01",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Nathan Kline Institute for Psychiatric Research",
"sponsor_slug": "nathan-kline-institute-for-psychiatric-research",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07126158",
"publication_url": "https://clinicaltrials.gov/study/NCT07126158",
"title": "Phase II Study of Stereotactic Body Radiotherapy Plus FAK and RAF/MEK Inhibition in Advanced Pancreatic Adenocarcinoma",
"has_exemption": false,
"start_date": "2026-04-10",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05763693",
"publication_url": "https://clinicaltrials.gov/study/NCT05763693",
"title": "Vitality in Infants Via Azithromycin for Neonates Trial",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07571161",
"publication_url": "https://clinicaltrials.gov/study/NCT07571161",
"title": "A Study of Donanemab Versus Placebo in Chinese Participants at Risk for Cognitive and Functional Decline of Alzheimer's Disease",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07191717",
"publication_url": "https://clinicaltrials.gov/study/NCT07191717",
"title": "Phase II Minimal Residual Disease Study of Selective Estrogen Receptor Degrader Imlunestrant With Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Abemaciclib in Patients With ER+ Breast Cancer (MIRI)",
"has_exemption": false,
"start_date": "2026-05-18",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonsson Comprehensive Cancer Center",
"sponsor_slug": "jonsson-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07710885",
"publication_url": "https://clinicaltrials.gov/study/NCT07710885",
"title": "A Phase 3, Randomized-Controlled, Open-Label, Multi-Regional, International Study of Futibatinib (TAS-120) and Zimberelimab (AB122) in Combination With Gemcitabine Plus Cisplatin Versus Durvalumab or Pembrolizumab in Combination With Gemcitabine Plus Cisplatin for Patients With First-Line Advanced Biliary Tract Cancers",
"has_exemption": false,
"start_date": "2026-06-24",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Taiho Pharmaceutical Co., Ltd.",
"sponsor_slug": "taiho-pharmaceutical-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07421518",
"publication_url": "https://clinicaltrials.gov/study/NCT07421518",
"title": "Ketone Monitoring Approaches for Diabetic Ketoacidosis Risk Mitigation in People With T1D on Adjunctive SGLT2 Inhibitors",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AdventHealth Translational Research Institute",
"sponsor_slug": "adventhealth-translational-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07050862",
"publication_url": "https://clinicaltrials.gov/study/NCT07050862",
"title": "Circuity-guided Repetitive Transcranial Magnetic Stimulation (rTMS) for Tobacco Use in Veterans: A Comparison of Insula-rTMS and Prefrontal-rTMS",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07263022",
"publication_url": "https://clinicaltrials.gov/study/NCT07263022",
"title": "Cognitive Strategies in Early Psychosis 2",
"has_exemption": false,
"start_date": "2026-07-17",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Minnesota",
"sponsor_slug": "university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06855433",
"publication_url": "https://clinicaltrials.gov/study/NCT06855433",
"title": "A Randomized, Double-Blind, Multi-Site Placebo Controlled Trial of Colchicine in Calcium Pyrophosphate Deposition Disease",
"has_exemption": false,
"start_date": "2026-08-12",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07770698",
"publication_url": "https://clinicaltrials.gov/study/NCT07770698",
"title": "A Phase 1/2a, Open-Label, Dose Finding and Expansion Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of Sonrotoclax (BGB-11417) in Combination With Other Agents in Pediatric Patients Aged 6 Months to 17 Years, With Relapsed or Refractory Acute Myeloid Leukemia and B-cell Acute Lymphoblastic Leukemia",
"has_exemption": false,
"start_date": "2026-10-31",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "BeOne Medicines",
"sponsor_slug": "beone-medicines",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07881120",
"publication_url": "https://clinicaltrials.gov/study/NCT07881120",
"title": "A 2-Stage Operationally Seamless Phase 2/3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Afimetoran in Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Manifestations and Refractory and/or Intolerant to Antimalarial Therapy",
"has_exemption": false,
"start_date": "2026-10-31",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Beeline Medicines Corporation",
"sponsor_slug": "beeline-medicines-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07577804",
"publication_url": "https://clinicaltrials.gov/study/NCT07577804",
"title": "A Phase III, Randomised, Double-blind, Two-arm Study to Investigate the Efficacy and Safety of Treatment With CHF10196 Tablets (Florensocatib) Compared With Placebo for up to 78 Weeks, Followed by an Open-label Extension, in Male and Female Participants 12 to 85 Years of Age With Bronchiectasis",
"has_exemption": false,
"start_date": "2026-11-30",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Chiesi Farmaceutici S.p.A.",
"sponsor_slug": "chiesi-farmaceutici-spa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05684159",
"publication_url": "https://clinicaltrials.gov/study/NCT05684159",
"title": "A Phase II, Open-Label Study of NM8074 in Patients With Atypical Hemolytic Uremic Syndrome (aHUS)",
"has_exemption": false,
"start_date": "2027-11-30",
"completion_date": "2030-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "NovelMed Therapeutics",
"sponsor_slug": "novelmed-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03346694",
"publication_url": "https://clinicaltrials.gov/study/NCT03346694",
"title": "Reducing Surgical Site Infection Rates Using an Alternative Sternal Dressing",
"has_exemption": false,
"start_date": "2018-05-01",
"completion_date": "2030-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07512336",
"publication_url": "https://clinicaltrials.gov/study/NCT07512336",
"title": "A Randomized Intra-Patient Controlled Trial of MagnetOs™ Putty vs Autograft in Instrumented Posterolateral Spinal Fusion in Idiopathic Scoliosis Patients",
"has_exemption": false,
"start_date": "2026-05-01",
"completion_date": "2030-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "UMC Utrecht",
"sponsor_slug": "umc-utrecht",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07118839",
"publication_url": "https://clinicaltrials.gov/study/NCT07118839",
"title": "MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder: A Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2026-05-18",
"completion_date": "2030-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07340554",
"publication_url": "https://clinicaltrials.gov/study/NCT07340554",
"title": "Neuroimaging of Instrumental Learning Networks in Adolescent Cannabis Use Treatment",
"has_exemption": false,
"start_date": "2026-06-15",
"completion_date": "2030-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06585410",
"publication_url": "https://clinicaltrials.gov/study/NCT06585410",
"title": "A Phase 3 Randomized Study of Intralesional Cemiplimab Versus Primary Surgery in Participants With Early Stage Cutaneous Squamous Cell Carcinoma (CSCC)",
"has_exemption": false,
"start_date": "2025-01-02",
"completion_date": "2030-05-03",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07284641",
"publication_url": "https://clinicaltrials.gov/study/NCT07284641",
"title": "Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)",
"has_exemption": false,
"start_date": "2026-05-04",
"completion_date": "2030-05-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Paul Szabolcs",
"sponsor_slug": "paul-szabolcs",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06663722",
"publication_url": "https://clinicaltrials.gov/study/NCT06663722",
"title": "A Phase II b Study of Axatilimab in Combination With Extracorporeal Photopheresis (ECP) in Chronic Graft-versus-Host Disease",
"has_exemption": false,
"start_date": "2025-05-05",
"completion_date": "2030-05-05",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Miami",
"sponsor_slug": "university-of-miami",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07863765",
"publication_url": "https://clinicaltrials.gov/study/NCT07863765",
"title": "Phase II Multi-Center Open-Label Trial of Enfortumab Vedotin Treatment for Patients With Aggressive Radioiodine Refractory Differentiated Thyroid Cancer, Aggressive Poorly Differentiated Thyroid Cancer, Anaplastic Thyroid Cancer, Medullary Thyroid Cancer and NUT Carcinoma",
"has_exemption": false,
"start_date": "2027-05-05",
"completion_date": "2030-05-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07603557",
"publication_url": "https://clinicaltrials.gov/study/NCT07603557",
"title": "A Phase 2, Multicenter, Open-Label Study of Zolacabtagene Autoleucel (BMS-986353), CD19-Targeted NEX-T CAR T Cells, in Participants With Chronic Immune Thrombocytopenia (cITP) and Autoimmune Hemolytic Anemia (AIHA)",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2030-05-06",
"has_results": false,
"results_due": false,
"sponsor_name": "Juno Therapeutics, Inc., a Bristol-Myers Squibb Company",
"sponsor_slug": "juno-therapeutics-inc-a-bristol-myers-squibb-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02653755",
"publication_url": "https://clinicaltrials.gov/study/NCT02653755",
"title": "The PRECISION Trial (Profiling Early Breast Cancer for Radiotherapy Omission): A Phase II Study of Breast-Conserving Surgery Without Adjuvant Radiotherapy for Favorable-Risk Breast Cancer",
"has_exemption": false,
"start_date": "2015-12-15",
"completion_date": "2030-05-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Dana-Farber Cancer Institute",
"sponsor_slug": "dana-farber-cancer-institute",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT07625215",
"publication_url": "https://clinicaltrials.gov/study/NCT07625215",
"title": "A Placebo-controlled, Parallel-group, Double Blind, Randomized, Multi-cohort Phase 2 Study to Investigate Efficacy, Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of BAY 3670549 in Adult Participants With Atrial Fibrillation.",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2030-05-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Bayer",
"sponsor_slug": "bayer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06841354",
"publication_url": "https://clinicaltrials.gov/study/NCT06841354",
"title": "A Phase 3, Randomized, Open-label Study Comparing Efficacy and Safety of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as a Monotherapy and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With Previously Untreated Locally Recurrent Unresectable or Metastatic Triple-Negative Breast Cancer Expressing PD-L1 at CPS Less Than 10 (TroFuse-011)",
"has_exemption": false,
"start_date": "2025-03-16",
"completion_date": "2030-05-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07636811",
"publication_url": "https://clinicaltrials.gov/study/NCT07636811",
"title": "A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study, to Evaluate Efficacy, Safety, Tolerability, and Pharmacodynamics of Intrathecally Administered Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)",
"has_exemption": false,
"start_date": "2026-08-17",
"completion_date": "2030-05-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Alnylam Pharmaceuticals",
"sponsor_slug": "alnylam-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07684612",
"publication_url": "https://clinicaltrials.gov/study/NCT07684612",
"title": "A Randomized, Open-Label, Multicenter, Phase 3 Study to Investigate Mocertatug Rezetecan With Bevacizumab Compared With Platinum Doublet With Bevacizumab in Participants With Platinum-Sensitive Ovarian Cancer",
"has_exemption": false,
"start_date": "2026-09-08",
"completion_date": "2030-05-21",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07447817",
"publication_url": "https://clinicaltrials.gov/study/NCT07447817",
"title": "Investigator-Initiated, Open-Label, Phase II Trial of Selinexor in Combination With Pacritinib in Patients With Myelofibrosis Who Are JAK Inhibitor-Naïve and Have Cytopenias (ILLUMINATE)",
"has_exemption": false,
"start_date": "2026-05-04",
"completion_date": "2030-05-24",
"has_results": false,
"results_due": false,
"sponsor_name": "John Mascarenhas",
"sponsor_slug": "john-mascarenhas",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06932757",
"publication_url": "https://clinicaltrials.gov/study/NCT06932757",
"title": "Phase 2 Trial of Adjuvant Quisinostat in High-Risk Uveal Melanoma",
"has_exemption": false,
"start_date": "2025-05-27",
"completion_date": "2030-05-27",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Miami",
"sponsor_slug": "university-of-miami",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05061550",
"publication_url": "https://clinicaltrials.gov/study/NCT05061550",
"title": "A Phase II, Open-label, Multicentre, Randomised Study of Neoadjuvant and Adjuvant Treatment in Patients With Resectable, Early-stage (II to IIIB) Non-small Cell Lung Cancer (NeoCOAST-2)",
"has_exemption": false,
"start_date": "2022-04-14",
"completion_date": "2030-05-28",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07052903",
"publication_url": "https://clinicaltrials.gov/study/NCT07052903",
"title": "TRITON-CM: A Phase 3 Global, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Transthyretin-Mediated Amyloidosis With Cardiomyopathy (ATTR Amyloidosis With Cardiomyopathy)",
"has_exemption": false,
"start_date": "2025-07-02",
"completion_date": "2030-05-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Alnylam Pharmaceuticals",
"sponsor_slug": "alnylam-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03701334",
"publication_url": "https://clinicaltrials.gov/study/NCT03701334",
"title": "A Phase III Multi-center, Randomized, Open-label Trial to Evaluate Efficacy and Safety of Ribociclib With Endocrine Therapy as an Adjuvant Treatment in Patients With Hormone Receptor-positive, HER2-negative Early Breast Cancer (New Adjuvant TriAl With Ribociclib [LEE011]: NATALEE)",
"has_exemption": false,
"start_date": "2018-12-07",
"completion_date": "2030-05-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05775367",
"publication_url": "https://clinicaltrials.gov/study/NCT05775367",
"title": "Cochlear Implantation in Infants and Toddlers With Single-Sided Deafness",
"has_exemption": false,
"start_date": "2023-07-07",
"completion_date": "2030-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of North Carolina, Chapel Hill",
"sponsor_slug": "university-of-north-carolina-chapel-hill",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06500884",
"publication_url": "https://clinicaltrials.gov/study/NCT06500884",
"title": "A Phase 2, Open-label, Randomized Study to Evaluate GPRC5D-related Oral Events",
"has_exemption": false,
"start_date": "2024-08-26",
"completion_date": "2030-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07681674",
"publication_url": "https://clinicaltrials.gov/study/NCT07681674",
"title": "Bicycle Continued Access Protocol (BiCAP) for Participants Receiving a Bicycle Investigational Product on a BicycleTx Limited-Sponsored Study",
"has_exemption": false,
"start_date": "2026-08-01",
"completion_date": "2030-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "BicycleTx Limited",
"sponsor_slug": "bicycletx-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07715799",
"publication_url": "https://clinicaltrials.gov/study/NCT07715799",
"title": "A Randomized Clinical Trial Using Noninvasive Brain Stimulation Combined With Written Exposure Therapy for PTSD in Military Personnel With TBI",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2030-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center at San Antonio",
"sponsor_slug": "the-university-of-texas-health-science-center-at-san-antonio",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07565194",
"publication_url": "https://clinicaltrials.gov/study/NCT07565194",
"title": "Arousal-related Memory of Movie Clips During Individualized IPS Targeting fMRI and TBS.",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2030-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07565207",
"publication_url": "https://clinicaltrials.gov/study/NCT07565207",
"title": "The Effect of Within-network aiTBS on Cortical Excitability, Intrinsic Oscillatory Bands, and Behavioral Task Performance",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2030-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07696988",
"publication_url": "https://clinicaltrials.gov/study/NCT07696988",
"title": "Peripheral Neural Stimulation to Improve Microvascular Function and Limb Health in Veterans With Diabetic Peripheral Neuropathy",
"has_exemption": false,
"start_date": "2026-11-02",
"completion_date": "2030-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02115295",
"publication_url": "https://clinicaltrials.gov/study/NCT02115295",
"title": "Phase II Study of Cladribine Plus Idarubicin Plus Cytarabine (ARAC) in Patients With AML, HR MDS, or Myeloid Blast Phase of CML",
"has_exemption": false,
"start_date": "2014-05-19",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02310399",
"publication_url": "https://clinicaltrials.gov/study/NCT02310399",
"title": "Auditory Brainstem Implant (ABI) in Children With No Cochleae or Auditory Nerves",
"has_exemption": false,
"start_date": "2014-05-31",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03394365",
"publication_url": "https://clinicaltrials.gov/study/NCT03394365",
"title": "Multicenter, Open-Label, Phase 3 Study of Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Subjects With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure of Rituximab or Rituximab and Chemotherapy",
"has_exemption": false,
"start_date": "2017-12-29",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Pierre Fabre Medicament",
"sponsor_slug": "pierre-fabre-medicament",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03618186",
"publication_url": "https://clinicaltrials.gov/study/NCT03618186",
"title": "Neuroimaging Study",
"has_exemption": false,
"start_date": "2018-11-26",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03821857",
"publication_url": "https://clinicaltrials.gov/study/NCT03821857",
"title": "Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease",
"has_exemption": false,
"start_date": "2019-06-27",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03972202",
"publication_url": "https://clinicaltrials.gov/study/NCT03972202",
"title": "The Role of Cerebellum in Speech",
"has_exemption": false,
"start_date": "2019-09-15",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05254327",
"publication_url": "https://clinicaltrials.gov/study/NCT05254327",
"title": "A Randomized Phase 2 Trial of the Efficacy and Safety of Short and Long Course Radiation Therapy With and Without BMX-001 as Part of Total Neoadjuvant Therapy in Patients With Newly Diagnosed Locally Advanced Rectal Adenocarcinoma",
"has_exemption": false,
"start_date": "2022-08-15",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Nebraska",
"sponsor_slug": "university-of-nebraska",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05200559",
"publication_url": "https://clinicaltrials.gov/study/NCT05200559",
"title": "The Efficacy of T-regulatory Cell Depletion With E7777 Combined With Immune Checkpoint Inhibitor, Pembrolizumab, in Recurrent or Metastatic Solid Tumors: Phase I/II Study",
"has_exemption": false,
"start_date": "2022-09-30",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Alexander B Olawaiye, MD",
"sponsor_slug": "alexander-b-olawaiye-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06205836",
"publication_url": "https://clinicaltrials.gov/study/NCT06205836",
"title": "Evaluating a Surgical-Sparing Approach Using Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer",
"has_exemption": false,
"start_date": "2024-06-13",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
"sponsor_slug": "sidney-kimmel-comprehensive-cancer-center-at-johns-hopkins",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06851338",
"publication_url": "https://clinicaltrials.gov/study/NCT06851338",
"title": "Pediatric Down Syndrome Post-Approval Study",
"has_exemption": false,
"start_date": "2025-02-28",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Inspire Medical Systems, Inc.",
"sponsor_slug": "inspire-medical-systems-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07010692",
"publication_url": "https://clinicaltrials.gov/study/NCT07010692",
"title": "Using Fractional Lasers and Tirbanibulin Ointment to Treat Keratinocyte Carcinomas",
"has_exemption": false,
"start_date": "2025-05-16",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Bruce Robinson, MD",
"sponsor_slug": "bruce-robinson-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06876662",
"publication_url": "https://clinicaltrials.gov/study/NCT06876662",
"title": "Long-Term Safety of Pirtobrutinib in Participants From Study LOXO-BTK-18001 With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma",
"has_exemption": false,
"start_date": "2025-05-20",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06876649",
"publication_url": "https://clinicaltrials.gov/study/NCT06876649",
"title": "A Master Protocol to Evaluate the Long-Term Safety of Pirtobrutinib",
"has_exemption": false,
"start_date": "2025-05-20",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06961955",
"publication_url": "https://clinicaltrials.gov/study/NCT06961955",
"title": "FAST NOVEMBER: A Phase II Randomized Trial of a 5 vs. 9-day Course of Whole Breast Radiotherapy With Boost for Early-stage Breast Cancer",
"has_exemption": false,
"start_date": "2025-05-21",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Utah",
"sponsor_slug": "university-of-utah",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07162181",
"publication_url": "https://clinicaltrials.gov/study/NCT07162181",
"title": "Long-Term Safety of Pirtobrutinib in Participants From Study J2N-MC-JZNJ With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma",
"has_exemption": false,
"start_date": "2025-08-07",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06814496",
"publication_url": "https://clinicaltrials.gov/study/NCT06814496",
"title": "RAdiation comBined With BIspecific T-Cell Engager in DLL3 Expressing Tumors (RABBIT) Study: A Phase I/II Study of AMG757 / Tarlatamab and Concurrent Radiation Therapy in Tumors With High Prevalence of DLL3",
"has_exemption": false,
"start_date": "2025-09-08",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Arizona",
"sponsor_slug": "university-of-arizona",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07186842",
"publication_url": "https://clinicaltrials.gov/study/NCT07186842",
"title": "First-in-human, Open-label, Multi-site, Phase I/IIa, Dose Escalation Trial With Expansion Cohorts to Evaluate Safety and Preliminary Efficacy of BNT329 in Participants With Advanced Solid Tumors Known to Express CA19-9",
"has_exemption": false,
"start_date": "2025-11-18",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Biontech SE",
"sponsor_slug": "biontech-se",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07097363",
"publication_url": "https://clinicaltrials.gov/study/NCT07097363",
"title": "A Pilot Study of Epcoritamab With Dose Adjusted Etoposide, Cyclophosphamide, Vincristine, Doxorubicin, Prednisone and Rituximab (EPOCH-R) for Upfront Treatment of Aggressive B-Cell Non-Hodgkin Lymphomas",
"has_exemption": false,
"start_date": "2025-12-07",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Washington",
"sponsor_slug": "university-of-washington",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07224438",
"publication_url": "https://clinicaltrials.gov/study/NCT07224438",
"title": "Kisspeptin Administration Subcutaneously to Patients With Hypothalamic Amenorrhea",
"has_exemption": false,
"start_date": "2025-12-09",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stephanie B. Seminara, MD",
"sponsor_slug": "stephanie-b-seminara-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07449702",
"publication_url": "https://clinicaltrials.gov/study/NCT07449702",
"title": "An Open-label Extension Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of ORKA-001 in Participants With Moderate-to-Severe Plaque Psoriasis",
"has_exemption": false,
"start_date": "2026-02-23",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Oruka Therapeutics, Inc.",
"sponsor_slug": "oruka-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07218341",
"publication_url": "https://clinicaltrials.gov/study/NCT07218341",
"title": "Long-Term Safety of Pirtobrutinib in Participants From Study LOXO-BTK-20020 With BTKi Pretreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma",
"has_exemption": false,
"start_date": "2026-03-09",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06410001",
"publication_url": "https://clinicaltrials.gov/study/NCT06410001",
"title": "CE-STAND: Cervical Epidural STimulation After Neurologic Damage",
"has_exemption": false,
"start_date": "2026-03-15",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Minnesota",
"sponsor_slug": "university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07526740",
"publication_url": "https://clinicaltrials.gov/study/NCT07526740",
"title": "Combining Brain Stimulation With Computerized Cognitive Training for MCI",
"has_exemption": false,
"start_date": "2026-03-16",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University of South Carolina",
"sponsor_slug": "medical-university-of-south-carolina",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07467707",
"publication_url": "https://clinicaltrials.gov/study/NCT07467707",
"title": "A Phase 3b Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Immunogenicity of an Adjuvanted Chikungunya Virus Virus-like Particle (CHIKV VLP) Vaccine for the Prevention of Chikungunya Disease in Adolescents (12 to <18 Years) and Adults (≥18 Years)",
"has_exemption": false,
"start_date": "2026-05-26",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Bavarian Nordic",
"sponsor_slug": "bavarian-nordic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07682311",
"publication_url": "https://clinicaltrials.gov/study/NCT07682311",
"title": "Automated Daytime Adaptive Deep Brain Stimulation Parameter Optimization in Patients Implanted With Percept Neurostimulator",
"has_exemption": false,
"start_date": "2026-06-04",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07641426",
"publication_url": "https://clinicaltrials.gov/study/NCT07641426",
"title": "A 2 Part Dose-escalation Safety and Efficacy Study of CID-103 in Adults With Active and Chronic Active Renal Allograft Antibody Mediated Rejection.",
"has_exemption": false,
"start_date": "2026-06-09",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "CASI Pharmaceuticals, Inc.",
"sponsor_slug": "casi-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07620574",
"publication_url": "https://clinicaltrials.gov/study/NCT07620574",
"title": "Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored Study",
"has_exemption": false,
"start_date": "2026-07-30",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Exelixis",
"sponsor_slug": "exelixis",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07298421",
"publication_url": "https://clinicaltrials.gov/study/NCT07298421",
"title": "A Phase III Randomized Double-Blind Multi-Center Treat-Through Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Children Aged 2-17 Years With Moderately to Severely Active Crohn's Disease",
"has_exemption": false,
"start_date": "2026-08-18",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07578467",
"publication_url": "https://clinicaltrials.gov/study/NCT07578467",
"title": "A Phase Ib/II Study Combining Neo-adjuvant ATR-inhibition With Nodal SBRT for Early-stage Resectable HPV+ OPSCCs",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Abramson Cancer Center at Penn Medicine",
"sponsor_slug": "abramson-cancer-center-at-penn-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06349083",
"publication_url": "https://clinicaltrials.gov/study/NCT06349083",
"title": "Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07699107",
"publication_url": "https://clinicaltrials.gov/study/NCT07699107",
"title": "Adalimumab Dose Adjustment for Pediatric Uveitis Treatment Trial",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Nisha Acharya",
"sponsor_slug": "nisha-acharya",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07576998",
"publication_url": "https://clinicaltrials.gov/study/NCT07576998",
"title": "PHIL™ (Precipitating Hydrophobic Injectable Liquid) Middle Meningeal Artery Embolization (MMAE) for First-Line Treatment of Chronic Subdural Hematoma (cSDH) IDE Trial (PHILFIRST)",
"has_exemption": false,
"start_date": "2026-12-31",
"completion_date": "2030-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Microvention-Terumo, Inc.",
"sponsor_slug": "microvention-terumo-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04900623",
"publication_url": "https://clinicaltrials.gov/study/NCT04900623",
"title": "Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study",
"has_exemption": false,
"start_date": "2021-07-02",
"completion_date": "2030-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonathan Schoenfeld, MD, MPH",
"sponsor_slug": "jonathan-schoenfeld-md-mph",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06872333",
"publication_url": "https://clinicaltrials.gov/study/NCT06872333",
"title": "Allogeneic Hematopoietic Stem Cell Transplant for Patients With High Risk Hemoglobinopathies and Other Red Cell Transfusion Dependent Disorders",
"has_exemption": false,
"start_date": "2024-11-19",
"completion_date": "2030-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Masonic Cancer Center, University of Minnesota",
"sponsor_slug": "masonic-cancer-center-university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06810778",
"publication_url": "https://clinicaltrials.gov/study/NCT06810778",
"title": "Phase I/II Study of Duvelisib and Venetoclax in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)",
"has_exemption": false,
"start_date": "2025-05-02",
"completion_date": "2030-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonsson Comprehensive Cancer Center",
"sponsor_slug": "jonsson-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07060066",
"publication_url": "https://clinicaltrials.gov/study/NCT07060066",
"title": "Bilateral Prefrontal and Insular TMS for Depression in Schizophrenia",
"has_exemption": false,
"start_date": "2025-10-23",
"completion_date": "2030-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07032389",
"publication_url": "https://clinicaltrials.gov/study/NCT07032389",
"title": "Polypill Strategy for the Treatment of Patients After Acute Coronary Syndromes - A Multicenter Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2025-12-05",
"completion_date": "2030-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07142551",
"publication_url": "https://clinicaltrials.gov/study/NCT07142551",
"title": "Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response Via Modulation of ANdrogen Receptor (the SPIDERMAN Trial)",
"has_exemption": false,
"start_date": "2026-03-09",
"completion_date": "2030-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
"sponsor_slug": "sidney-kimmel-comprehensive-cancer-center-at-johns-hopkins",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07546942",
"publication_url": "https://clinicaltrials.gov/study/NCT07546942",
"title": "Autism Spectral Disorder (ASD) In Adolescent-Adults Treated by Multimodal Protocol: IV Autologous cSVF, Interval IV Autologous MSCs (Cryopreserved), Strick Ketogenic Diet RESET Program, and Fecal Microbiota Transplantation (FMT)",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2030-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Black Tie Medical, Inc.",
"sponsor_slug": "black-tie-medical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07566039",
"publication_url": "https://clinicaltrials.gov/study/NCT07566039",
"title": "Prospective Cohort Study of Athletes Following an Injection of Platelet-Poor Plasma Into an Acute Muscle Injury",
"has_exemption": false,
"start_date": "2026-05-01",
"completion_date": "2030-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07356284",
"publication_url": "https://clinicaltrials.gov/study/NCT07356284",
"title": "Emergent Large Vessel Occlusion Endovascular Rescue Therapy With Underlying Intracranial Stenosis",
"has_exemption": false,
"start_date": "2026-05-19",
"completion_date": "2030-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "ProMedica Health System",
"sponsor_slug": "promedica-health-system",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04457076",
"publication_url": "https://clinicaltrials.gov/study/NCT04457076",
"title": "A Phase 3, Prospective, Multi-Center, Single-Arm, Open-Label Study to Evaluate LevoCept™, a Long-Acting Reversible Intrauterine System for Contraceptive Efficacy, Safety, and Tolerability",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2030-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Sebela Women's Health Inc.",
"sponsor_slug": "sebela-womens-health-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06996730",
"publication_url": "https://clinicaltrials.gov/study/NCT06996730",
"title": "A Double-Blind, Placebo-Controlled, Double-Dummy Study of Donanemab and RG6289 in PSEN1 E280A Mutation Carriers, and in Non-Randomized, Placebo-Treated Non-Carriers From the Same Kindred, to Evaluate the Efficacy and Safety of Donanemab, RG6289, or the Combination of Donanemab and RG6289, in the Treatment of Autosomal-Dominant Alzheimer's Disease",
"has_exemption": false,
"start_date": "2026-07-08",
"completion_date": "2030-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Banner Health",
"sponsor_slug": "banner-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07420218",
"publication_url": "https://clinicaltrials.gov/study/NCT07420218",
"title": "Impact of FSH and Estradiol on Sympathetic Function in Menopausal Women",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2030-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Delaware",
"sponsor_slug": "university-of-delaware",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07526545",
"publication_url": "https://clinicaltrials.gov/study/NCT07526545",
"title": "UPRISE (Urine Prostate Screening Integrated With MRI for Prostate Cancer Early Detection)",
"has_exemption": false,
"start_date": "2026-12-01",
"completion_date": "2030-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan Rogel Cancer Center",
"sponsor_slug": "university-of-michigan-rogel-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07859059",
"publication_url": "https://clinicaltrials.gov/study/NCT07859059",
"title": "A Phase I/II Study of Metronomic Temozolomide With Dexbrompheniramine for Patients With Recurrent High-Grade Glioma/Glioblastoma",
"has_exemption": false,
"start_date": "2027-06-01",
"completion_date": "2030-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Nebraska",
"sponsor_slug": "university-of-nebraska",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06800092",
"publication_url": "https://clinicaltrials.gov/study/NCT06800092",
"title": "Sildenafil to Prevent and Reduce Cancer Related Cognitive Impairment",
"has_exemption": false,
"start_date": "2027-06-15",
"completion_date": "2030-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Medical Branch, Galveston",
"sponsor_slug": "the-university-of-texas-medical-branch-galveston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07019454",
"publication_url": "https://clinicaltrials.gov/study/NCT07019454",
"title": "Baystate Health Physician Sponsored - Investigational Device Exception: Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Juxtarenal Aortic Aneurysms",
"has_exemption": false,
"start_date": "2025-06-03",
"completion_date": "2030-06-03",
"has_results": false,
"results_due": false,
"sponsor_name": "Baystate Medical Center",
"sponsor_slug": "baystate-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07215585",
"publication_url": "https://clinicaltrials.gov/study/NCT07215585",
"title": "A Phase III, Multicentre, Open-Label, Randomised Study Evaluating the Efficacy and Safety of R-mini-CHOP x2 Followed by AZD0486 Versus R-mini-CHOP x6 in Elderly or Unfit Participants With Newly Diagnosed Large B-cell Lymphoma (SOUNDTRACK-D2)",
"has_exemption": false,
"start_date": "2025-11-11",
"completion_date": "2030-06-10",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07154290",
"publication_url": "https://clinicaltrials.gov/study/NCT07154290",
"title": "A Phase 2 Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Treatment-Experienced Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)",
"has_exemption": false,
"start_date": "2026-03-18",
"completion_date": "2030-06-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05163288",
"publication_url": "https://clinicaltrials.gov/study/NCT05163288",
"title": "Effects of N-Acetyl-L-Leucine on Niemann-Pick Disease Type C (NPC): A Phase III, Randomized, Placebo-controlled, Double-blind, Crossover Study",
"has_exemption": false,
"start_date": "2022-06-30",
"completion_date": "2030-06-12",
"has_results": false,
"results_due": false,
"sponsor_name": "IntraBio Inc",
"sponsor_slug": "intrabio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07226999",
"publication_url": "https://clinicaltrials.gov/study/NCT07226999",
"title": "A GLOBAL PHASE 2/3 INTERVENTIONAL STUDY OF PF-08634404 IN COMBINATION WITH CHEMOTHERAPY IN PARTICIPANTS WITH EXTENSIVE STAGE SMALL CELL LUNG CANCER",
"has_exemption": false,
"start_date": "2025-12-09",
"completion_date": "2030-06-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04452591",
"publication_url": "https://clinicaltrials.gov/study/NCT04452591",
"title": "A Phase 3 Study of Cretostimogene Grenadenorepvec in Patients With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Bacillus-Calmette-Guerin (BCG)",
"has_exemption": false,
"start_date": "2020-10-27",
"completion_date": "2030-06-16",
"has_results": false,
"results_due": false,
"sponsor_name": "CG Oncology, Inc.",
"sponsor_slug": "cg-oncology-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05170204",
"publication_url": "https://clinicaltrials.gov/study/NCT05170204",
"title": "A Phase I-III, Multicenter Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of Patients Selected According to Biomarker Status, With Locally Advanced, Unresectable, Stage III Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2022-11-01",
"completion_date": "2030-06-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07116616",
"publication_url": "https://clinicaltrials.gov/study/NCT07116616",
"title": "A Phase 1/2, Open-label, Multicenter Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma",
"has_exemption": false,
"start_date": "2025-09-30",
"completion_date": "2030-06-17",
"has_results": false,
"results_due": false,
"sponsor_name": "ModernaTX, Inc.",
"sponsor_slug": "modernatx-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07851025",
"publication_url": "https://clinicaltrials.gov/study/NCT07851025",
"title": "A Randomised, Open-label, Phase III Study of Torvutatug Samrotecan in Combination With Bevacizumab Versus Bevacizumab Monotherapy as First-line Maintenance Treatment in Participants With Homologous Recombination Deficiency (HRD) Negative Advanced Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (TREVI-OC-02)",
"has_exemption": false,
"start_date": "2026-09-16",
"completion_date": "2030-06-18",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07639242",
"publication_url": "https://clinicaltrials.gov/study/NCT07639242",
"title": "Olomorasib Plus Pembrolizumab as First-Line Treatment for KRAS G12C Mutant, PD-L1 TPS 1-49% Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)",
"has_exemption": false,
"start_date": "2026-10-31",
"completion_date": "2030-06-21",
"has_results": false,
"results_due": false,
"sponsor_name": "UNC Lineberger Comprehensive Cancer Center",
"sponsor_slug": "unc-lineberger-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06077760",
"publication_url": "https://clinicaltrials.gov/study/NCT06077760",
"title": "A Phase 3, Randomized, Double-blind, Placebo- and Active-Comparator-Controlled Clinical Study of Adjuvant V940 (mRNA-4157) Plus Pembrolizumab Versus Adjuvant Placebo Plus Pembrolizumab in Participants With Resected Stage II, IIIA, IIIB (N2) Non-small Cell Lung Cancer (INTerpath-002)",
"has_exemption": false,
"start_date": "2023-12-06",
"completion_date": "2030-06-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07603856",
"publication_url": "https://clinicaltrials.gov/study/NCT07603856",
"title": "A Randomized Phase II Study of Radiotherapy Plus Immune Checkpoint Inhibitor Therapy Versus Standard of Care Chemotherapy in Patients With Metastatic or Relapsed Non-Small Cell Lung Cancer Previously Treated With Immunotherapy",
"has_exemption": false,
"start_date": "2026-12-12",
"completion_date": "2030-06-25",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06578247",
"publication_url": "https://clinicaltrials.gov/study/NCT06578247",
"title": "A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial Of Quizartinib Administered in Combination With Induction and Consolidation Chemotherapy and Administered as Maintenance Therapy in Adult Patients With Newly Diagnosed FLT3-ITD Negative Acute Myeloid Leukemia",
"has_exemption": false,
"start_date": "2024-11-19",
"completion_date": "2030-06-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Daiichi Sankyo",
"sponsor_slug": "daiichi-sankyo",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07029828",
"publication_url": "https://clinicaltrials.gov/study/NCT07029828",
"title": "A LONG-TERM, DOUBLE-BLIND EXTENSION STUDY TO INVESTIGATE THE SAFETY AND EFFICACY OF RITLECITINIB IN PARTICIPANTS WITH SEVERE ALOPECIA AREATA WHO PREVIOUSLY COMPLETED STUDIES B7981027 OR B7981031",
"has_exemption": false,
"start_date": "2025-09-10",
"completion_date": "2030-06-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04004169",
"publication_url": "https://clinicaltrials.gov/study/NCT04004169",
"title": "Closed-Loop Deep Brain Stimulation for Treatment-Resistant Depression",
"has_exemption": false,
"start_date": "2019-07-18",
"completion_date": "2030-06-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Andrew Krystal",
"sponsor_slug": "andrew-krystal",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05161195",
"publication_url": "https://clinicaltrials.gov/study/NCT05161195",
"title": "A Post-trial Access Roll-over Study to Allow Access to Ribociclib (LEE011) for Patients Who Are on Ribociclib Treatment in Novartis-sponsored Study",
"has_exemption": false,
"start_date": "2022-07-07",
"completion_date": "2030-06-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07127913",
"publication_url": "https://clinicaltrials.gov/study/NCT07127913",
"title": "Closed-Loop Deep Brain Stimulation for Bipolar Depression (PReSiDio-BP)",
"has_exemption": false,
"start_date": "2025-07-16",
"completion_date": "2030-06-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Andrew Krystal",
"sponsor_slug": "andrew-krystal",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06994845",
"publication_url": "https://clinicaltrials.gov/study/NCT06994845",
"title": "A Single-arm, Multicenter, Phase III Study to Assess Efficacy, Pharmacokinetics, Safety and Tolerability of Iptacopan in Pediatric Patients of 2 to <18 Years of Age With Primary Immunoglobulin A Nephropathy (IgAN)",
"has_exemption": false,
"start_date": "2025-11-27",
"completion_date": "2030-06-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06725550",
"publication_url": "https://clinicaltrials.gov/study/NCT06725550",
"title": "Integrative Medicine in Pain Management in Sickle Cell Disease: Assessing the Clinical Efficacy and Neurobiological Impact With Acupuncture, 2.0",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2030-06-28",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Cincinnati",
"sponsor_slug": "university-of-cincinnati",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06966362",
"publication_url": "https://clinicaltrials.gov/study/NCT06966362",
"title": "Varenicline for Smoking Reduction in Veterans Unwilling to Quit",
"has_exemption": false,
"start_date": "2026-08-17",
"completion_date": "2030-06-28",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03971669",
"publication_url": "https://clinicaltrials.gov/study/NCT03971669",
"title": "Collection of Blood Samples for In-Vitro Studies From Healthy Adult Blood Donors Who Have Received Oral Typhoid Vaccine (TY21A)",
"has_exemption": false,
"start_date": "2004-01-16",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Maryland, Baltimore",
"sponsor_slug": "university-of-maryland-baltimore",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT01630850",
"publication_url": "https://clinicaltrials.gov/study/NCT01630850",
"title": "Islet Transplantation in Patients With \"Brittle\" Type I Diabetes",
"has_exemption": false,
"start_date": "2012-05-31",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03434392",
"publication_url": "https://clinicaltrials.gov/study/NCT03434392",
"title": "QST Study: Predicting Treatment Response in Chronic Pancreatitis Using Quantitative Sensory Testing",
"has_exemption": false,
"start_date": "2017-10-24",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Anna Evans Phillips",
"sponsor_slug": "anna-evans-phillips",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04305145",
"publication_url": "https://clinicaltrials.gov/study/NCT04305145",
"title": "Phase II Study of Infliximab for the Treatment of Immune Checkpoint Inhibitor Colitis",
"has_exemption": false,
"start_date": "2020-08-31",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04753970",
"publication_url": "https://clinicaltrials.gov/study/NCT04753970",
"title": "Retinal Vasoreactivity is a Marker for Cerebral Small Vessel Disease Progression",
"has_exemption": false,
"start_date": "2021-02-09",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05422222",
"publication_url": "https://clinicaltrials.gov/study/NCT05422222",
"title": "A Phase 3 Study Evaluating the Pharmacokinetics, Safety, and Tolerability of VX-121/Tezacaftor/Deutivacaftor Triple Combination Therapy in Cystic Fibrosis Subjects 1 Through 11 Years of Age",
"has_exemption": false,
"start_date": "2022-06-21",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Vertex Pharmaceuticals Incorporated",
"sponsor_slug": "vertex-pharmaceuticals-incorporated",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05551858",
"publication_url": "https://clinicaltrials.gov/study/NCT05551858",
"title": "A Phase 1/2 Trial to Test the Safety of a CCK Receptor Antagonist, Proglumide, in Management of Chronic Pancreatitis Symptoms and Pain for 12 to 24 Months",
"has_exemption": false,
"start_date": "2022-11-17",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Georgetown University",
"sponsor_slug": "georgetown-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05633615",
"publication_url": "https://clinicaltrials.gov/study/NCT05633615",
"title": "A Randomized Phase II Trial of Consolidation Therapy Following CD19 CAR T-Cell Treatment for Relapsed/Refractory Diffuse Large B-Cell Lymphoma or Grade IIIB Follicular Lymphoma",
"has_exemption": false,
"start_date": "2023-06-12",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "SWOG Cancer Research Network",
"sponsor_slug": "swog-cancer-research-network",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06118892",
"publication_url": "https://clinicaltrials.gov/study/NCT06118892",
"title": "Post-Market Evaluation of the MISHA® Knee System for Symptom Relief in Subjects With Medial Knee Osteoarthritis",
"has_exemption": false,
"start_date": "2023-11-03",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Moximed",
"sponsor_slug": "moximed",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06384573",
"publication_url": "https://clinicaltrials.gov/study/NCT06384573",
"title": "The Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) Amyloid Removal Trial (ART): A Phase IIIb/IV Open-Label Study of Lecanemab to Evaluate Prevention and Progression of Dominantly Inherited Alzheimer's Disease",
"has_exemption": false,
"start_date": "2024-06-10",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07580183",
"publication_url": "https://clinicaltrials.gov/study/NCT07580183",
"title": "Investigations of Spatial Recognition Memory to Improve Cognitive Outcomes in Epilepsy Surgery",
"has_exemption": false,
"start_date": "2024-07-01",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Davis",
"sponsor_slug": "university-of-california-davis",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06241430",
"publication_url": "https://clinicaltrials.gov/study/NCT06241430",
"title": "Hemodynamic-Guided Optimization With the CardioMEMS Device of Patients With Heart Failure and Secondary Mitral Regurgitation Undergoing Mitral Transcatheter Edge-to-Edge Repair With the MitraClip Device",
"has_exemption": false,
"start_date": "2024-12-18",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Columbia University",
"sponsor_slug": "columbia-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06767683",
"publication_url": "https://clinicaltrials.gov/study/NCT06767683",
"title": "An Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability, and Durability of Treatment Effect of ALKS 2680 in Subjects With Narcolepsy Type 1 and Type 2 and Idiopathic Hypersomnia",
"has_exemption": false,
"start_date": "2025-01-27",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Alkermes, Inc.",
"sponsor_slug": "alkermes-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06904313",
"publication_url": "https://clinicaltrials.gov/study/NCT06904313",
"title": "Evaluation of Ultralow Dose PET Imaging for Detecting PSMA Expression",
"has_exemption": false,
"start_date": "2025-05-12",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Akiva Mintz",
"sponsor_slug": "akiva-mintz",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06956391",
"publication_url": "https://clinicaltrials.gov/study/NCT06956391",
"title": "Evaluation of Ultralow Dose PET Imaging for Detecting 18F-FDG Uptake",
"has_exemption": false,
"start_date": "2025-05-12",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Akiva Mintz",
"sponsor_slug": "akiva-mintz",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07542158",
"publication_url": "https://clinicaltrials.gov/study/NCT07542158",
"title": "Evaluation of Ultralow Dose PET Imaging for Detecting 18F-FDOPA Uptake",
"has_exemption": false,
"start_date": "2025-05-12",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Akiva Mintz",
"sponsor_slug": "akiva-mintz",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07012993",
"publication_url": "https://clinicaltrials.gov/study/NCT07012993",
"title": "Evaluation of Ultralow Dose PET Imaging for Detecting Amyloid Tracer Uptake",
"has_exemption": false,
"start_date": "2025-05-20",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Akiva Mintz",
"sponsor_slug": "akiva-mintz",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07038343",
"publication_url": "https://clinicaltrials.gov/study/NCT07038343",
"title": "A Phase 1/2, First-in-human Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2025-06-04",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Avenzo Therapeutics, Inc.",
"sponsor_slug": "avenzo-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06464926",
"publication_url": "https://clinicaltrials.gov/study/NCT06464926",
"title": "A Prospective Randomized Controlled Trial of Chronic Nausea and Vomiting in Patients With Normal Gastric Emptying Using the Enterra® Therapy System",
"has_exemption": false,
"start_date": "2025-06-23",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Enterra Medical, Inc.",
"sponsor_slug": "enterra-medical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06953089",
"publication_url": "https://clinicaltrials.gov/study/NCT06953089",
"title": "A Phase II, Multicenter, Open-Label Trial of DB-1311 in Combination With BNT327 or DB-1305 in Participants With Advanced/Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2025-07-18",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "DualityBio Inc.",
"sponsor_slug": "dualitybio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07284563",
"publication_url": "https://clinicaltrials.gov/study/NCT07284563",
"title": "Evaluation of Ultralow Dose PET Imaging for Detecting 18F-NaF Uptake",
"has_exemption": false,
"start_date": "2025-09-01",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Akiva Mintz",
"sponsor_slug": "akiva-mintz",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06726161",
"publication_url": "https://clinicaltrials.gov/study/NCT06726161",
"title": "Phase 1/2 Randomized, Controlled, Open-label Trial of Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ Unresectable Hepatocellular Carcinoma (HCC)",
"has_exemption": false,
"start_date": "2025-09-05",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "RayzeBio, Inc.",
"sponsor_slug": "rayzebio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07212686",
"publication_url": "https://clinicaltrials.gov/study/NCT07212686",
"title": "An Open-Label, Single-Center Study of Synthetic Angiotensin II/Giapreza in Pediatric Patients With Refractory Hypotension Despite Receiving Fluid Therapy and Vasoactive Therapy",
"has_exemption": false,
"start_date": "2025-09-09",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Todd Sweberg",
"sponsor_slug": "todd-sweberg",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06520098",
"publication_url": "https://clinicaltrials.gov/study/NCT06520098",
"title": "Benefit of Venetoclax Addition (\"Benefit VA\") in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)",
"has_exemption": false,
"start_date": "2025-10-01",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07284576",
"publication_url": "https://clinicaltrials.gov/study/NCT07284576",
"title": "Evaluation of 0.25mCi PET Imaging for Detecting Cardiac Perfusion",
"has_exemption": false,
"start_date": "2025-12-16",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Akiva Mintz",
"sponsor_slug": "akiva-mintz",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06949423",
"publication_url": "https://clinicaltrials.gov/study/NCT06949423",
"title": "Accessing the Impact of Deep TMS Neuromodulation on Neural Circuits Associated With Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2025-12-17",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07668869",
"publication_url": "https://clinicaltrials.gov/study/NCT07668869",
"title": "Tumor Treating Fields (TTFields) Concomitant With Stereotactic Radiosurgery Based on FET-PET vs TTFields Alone for the Treatment of Recurrent, Glioblastoma (Tarrget 2.0)",
"has_exemption": false,
"start_date": "2025-12-30",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Prof. Franciszek Lukaszczyk Memorial Oncology Center",
"sponsor_slug": "prof-franciszek-lukaszczyk-memorial-oncology-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07214649",
"publication_url": "https://clinicaltrials.gov/study/NCT07214649",
"title": "A Prospective Study Using Patient-Derived Extrahepatic Cholangiocyte Organoids for Refractory Bile Leaks",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Fondazione Policlinico Universitario Agostino Gemelli IRCCS",
"sponsor_slug": "fondazione-policlinico-universitario-agostino-gemelli-irccs",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07084441",
"publication_url": "https://clinicaltrials.gov/study/NCT07084441",
"title": "Comparison of Outcomes of Management of Bowel Obstruction",
"has_exemption": false,
"start_date": "2026-02-03",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Washington",
"sponsor_slug": "university-of-washington",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07223814",
"publication_url": "https://clinicaltrials.gov/study/NCT07223814",
"title": "Bleximenib or Placebo in Combination With Standard Induction and Consolidation Therapy Followed by Maintenance for the Treatment of Patients With Newly Diagnosed KMT2A-rearranged or NPM1-mutant Acute Myeloid Leukemia Eligible for Intensive Chemotherapy: a Double-blind Phase 3 Study",
"has_exemption": false,
"start_date": "2026-03-01",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Stichting Hemato-Oncologie voor Volwassenen Nederland",
"sponsor_slug": "stichting-hemato-oncologie-voor-volwassenen-nederland",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06474273",
"publication_url": "https://clinicaltrials.gov/study/NCT06474273",
"title": "A Multicenter Randomized Controlled Trial to Treat Acute t Cell Mediated Rejection in Kidney and Kidney-pancreas Transplant Recipients",
"has_exemption": false,
"start_date": "2026-03-13",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Sydney",
"sponsor_slug": "university-of-sydney",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07067463",
"publication_url": "https://clinicaltrials.gov/study/NCT07067463",
"title": "A Phase 3, Randomized, Double-blind, Efficacy and Safety Study Comparing Orelabrutinib to Placebo in Patients With Primary Progressive Multiple Sclerosis",
"has_exemption": false,
"start_date": "2026-03-23",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Zenas BioPharma (USA), LLC",
"sponsor_slug": "zenas-biopharma-usa-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07299019",
"publication_url": "https://clinicaltrials.gov/study/NCT07299019",
"title": "A Phase 3, Randomized, Double-blind, Efficacy and Safety Study Comparing Orelabrutinib to Placebo in Patients With Non-active Secondary Progressive Multiple Sclerosis",
"has_exemption": false,
"start_date": "2026-03-23",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Zenas BioPharma (USA), LLC",
"sponsor_slug": "zenas-biopharma-usa-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07415044",
"publication_url": "https://clinicaltrials.gov/study/NCT07415044",
"title": "A Randomized, Multicenter, Double-Blind, Placebo-Controlled Development Program to Evaluate the Efficacy and Safety of LY4268989 (MORF-057) for the Treatment of Adults With Moderately to Severely Active Ulcerative Colitis (EMERALD-3)",
"has_exemption": false,
"start_date": "2026-03-26",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07428499",
"publication_url": "https://clinicaltrials.gov/study/NCT07428499",
"title": "A Phase 3 Extension Study of siRNA Targeting of Prekallikrein With ADX-324 in Participants With Hereditary Angioedema",
"has_exemption": false,
"start_date": "2026-04-02",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "ADARx Pharmaceuticals, Inc.",
"sponsor_slug": "adarx-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07135596",
"publication_url": "https://clinicaltrials.gov/study/NCT07135596",
"title": "Research on the Effectiveness and Safety of Treatment With OviTex® PRS - a Breast Reconstruction Evaluation",
"has_exemption": false,
"start_date": "2026-04-10",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Tela Bio Inc",
"sponsor_slug": "tela-bio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07566052",
"publication_url": "https://clinicaltrials.gov/study/NCT07566052",
"title": "A Randomized, Open-label, Phase 3 Study of Setidegrasib (ASP3082) Versus Docetaxel in Participants With KRAS G12D-mutated Locally Advanced (Unresectable) or Metastatic Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on or After Platinum Based Chemotherapy and Checkpoint Inhibitor Therapy (CPI)",
"has_exemption": false,
"start_date": "2026-04-28",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Astellas Pharma Global Development, Inc.",
"sponsor_slug": "astellas-pharma-global-development-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07475286",
"publication_url": "https://clinicaltrials.gov/study/NCT07475286",
"title": "A Phase II Single Arm Study of Combined Systemic and Intraperitoneal Chemotherapy for Synchronous Gastric and/or Gastroesophageal Peritoneal Carcinomatosis",
"has_exemption": false,
"start_date": "2026-06-12",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Mohammad Haroon Asif Choudry",
"sponsor_slug": "mohammad-haroon-asif-choudry",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07436793",
"publication_url": "https://clinicaltrials.gov/study/NCT07436793",
"title": "Evaluating Promising Progestins in Endometrial Cancer Through a Rotating Umbrella Surgical Window Trial - The PRO-WINDOW TRIAL for Endometrial Cancer",
"has_exemption": false,
"start_date": "2026-06-15",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "New Mexico Cancer Research Alliance",
"sponsor_slug": "new-mexico-cancer-research-alliance",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07635940",
"publication_url": "https://clinicaltrials.gov/study/NCT07635940",
"title": "Effects of Transcranial Magnetic Stimulation on Social Cognition, Cognitive Processing, and Functional Brain Architecture in Psychopathy",
"has_exemption": false,
"start_date": "2026-07-13",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07398508",
"publication_url": "https://clinicaltrials.gov/study/NCT07398508",
"title": "Phase I/II Study of NORTHERA (DROXIDOPA) for Dysautonomia in Pediatric Survivors of Menkes Disease: Double-blind Placebo-controlled Randomized Crossover Clinical Trial",
"has_exemption": false,
"start_date": "2026-08-10",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Stephen G. Kaler",
"sponsor_slug": "stephen-g-kaler",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07265830",
"publication_url": "https://clinicaltrials.gov/study/NCT07265830",
"title": "The Building Adaptive School-based Interventions for Caries Study (BASICS): A Phase III Sequential, Multiple-Assignment, Randomized Trial of Minimally Invasive Therapies to Reduce Treatment Nonresponse",
"has_exemption": false,
"start_date": "2026-08-18",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07680829",
"publication_url": "https://clinicaltrials.gov/study/NCT07680829",
"title": "A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial to Evaluate Efficacy and Safety of DR10624 Added to Standard Icosapent Ethyl Therapy in Adults With Severe Hypertriglyceridemia",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Zhejiang Doer Biologics Co., Ltd.",
"sponsor_slug": "zhejiang-doer-biologics-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07745569",
"publication_url": "https://clinicaltrials.gov/study/NCT07745569",
"title": "Precision Phenotyping of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of New Mexico",
"sponsor_slug": "university-of-new-mexico",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07673250",
"publication_url": "https://clinicaltrials.gov/study/NCT07673250",
"title": "Personalized Ventilator Settings for Patients on ECMO (PEEPECMO)",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07210606",
"publication_url": "https://clinicaltrials.gov/study/NCT07210606",
"title": "Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment",
"has_exemption": false,
"start_date": "2026-09-16",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07849530",
"publication_url": "https://clinicaltrials.gov/study/NCT07849530",
"title": "Developing Transcranial Magnetic Stimulation as a Therapeutic Modality for Methamphetamine Use Disorder During Pregnancy",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Utah",
"sponsor_slug": "university-of-utah",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07873450",
"publication_url": "https://clinicaltrials.gov/study/NCT07873450",
"title": "A First-in-Human Phase 1/2 Dose Escalation and Treatment Optimization Study Evaluating Safety, Tolerability, and Preliminary Efficacy of [225Ac]Ac-FL-261 in Participants With Solid Tumors Overexpressing c-MET",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Full-Life Technologies UK Limited",
"sponsor_slug": "full-life-technologies-uk-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07839013",
"publication_url": "https://clinicaltrials.gov/study/NCT07839013",
"title": "Brain Function and Cognitive Control Training in Children With Obsessive-Compulsive Symptoms",
"has_exemption": false,
"start_date": "2026-10-15",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Columbia University",
"sponsor_slug": "columbia-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07632898",
"publication_url": "https://clinicaltrials.gov/study/NCT07632898",
"title": "Open-Label, Long-Term Extension Study to Evaluate the Safety and Tolerability of IKT-001 in Pulmonary Arterial Hypertension",
"has_exemption": false,
"start_date": "2026-10-23",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Inhibikase Therapeutics",
"sponsor_slug": "inhibikase-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07763873",
"publication_url": "https://clinicaltrials.gov/study/NCT07763873",
"title": "A Pre-Market, Multicentre, Prospective, Open-Label, Within-Subject, Non-Randomised, Interventional Study Examining Acceptability of Auditory Implant Fitting Software Technologies",
"has_exemption": false,
"start_date": "2026-10-31",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Cochlear",
"sponsor_slug": "cochlear",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07850076",
"publication_url": "https://clinicaltrials.gov/study/NCT07850076",
"title": "Official Title: A Phase 1/2 Multicenter, Open-label, First-in-Human Trial Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of CTX460, a Lipid Nanoparticle Formulation of SyNTase Editing Components for In Vivo Editing of the Serine Protease Inhibitor A1 (SERPINA1) Gene in Adults With Emphysema Associated With Severe Alpha-1 Antitrypsin Deficiency (AATD)",
"has_exemption": false,
"start_date": "2026-10-31",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "CRISPR Therapeutics",
"sponsor_slug": "crispr-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07573436",
"publication_url": "https://clinicaltrials.gov/study/NCT07573436",
"title": "A Phase 1/2 Study of Loncastuximab Tesirine and Rituximab as First-line Therapy in Patients With Post-transplant Lymphoproliferative Disorder (PLUTO)",
"has_exemption": false,
"start_date": "2026-11-30",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Utah",
"sponsor_slug": "university-of-utah",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07766317",
"publication_url": "https://clinicaltrials.gov/study/NCT07766317",
"title": "A Phase I/II Open-Label Clinical Study of Autologous Tumor Infiltrating Lymphocyte Infusion (GT201) in the Treatment of Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2026-11-30",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Gritbio Medicine, Inc.",
"sponsor_slug": "gritbio-medicine-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07836023",
"publication_url": "https://clinicaltrials.gov/study/NCT07836023",
"title": "Unbinding Forever Chemicals: an Intervention Trial for Reducing PFAS Body Burden and Assessing the Role of the Microbiome",
"has_exemption": false,
"start_date": "2026-11-30",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07726862",
"publication_url": "https://clinicaltrials.gov/study/NCT07726862",
"title": "Characterizing Local Mucosal Responses to Live Attenuated Influenza Vaccine in Healthy Adults",
"has_exemption": false,
"start_date": "2026-12-01",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04172779",
"publication_url": "https://clinicaltrials.gov/study/NCT04172779",
"title": "Phase II Clinical Trial of Low-dose Erlotinib for Hepatocellular Carcinoma Chemoprevention",
"has_exemption": false,
"start_date": "2026-12-31",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07796100",
"publication_url": "https://clinicaltrials.gov/study/NCT07796100",
"title": "A Randomized, Open-Label, Phase 3 Study of ZL-1310, a DLL3 Antibody-drug Conjugate (ADC) in Combination With a Checkpoint Inhibitor Compared to Standard of Care Platinum Based Chemotherapy With a Checkpoint Inhibitor as First-line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2026-12-31",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Zai Lab (Shanghai) Co., Ltd.",
"sponsor_slug": "zai-lab-shanghai-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07288463",
"publication_url": "https://clinicaltrials.gov/study/NCT07288463",
"title": "Hearing Loss and Brain Health Study",
"has_exemption": false,
"start_date": "2027-07-01",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Southern California",
"sponsor_slug": "university-of-southern-california",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05976802",
"publication_url": "https://clinicaltrials.gov/study/NCT05976802",
"title": "A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Dose Ranging Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Rectal Foam BID for 2 Weeks, Followed by QD for 4 Weeks, in Pediatric Patients Aged 5 to 17 Years With Active, Mild to Moderate Distal Ulcerative Colitis",
"has_exemption": false,
"start_date": "2029-06-30",
"completion_date": "2030-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Bausch Health Americas, Inc.",
"sponsor_slug": "bausch-health-americas-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04814082",
"publication_url": "https://clinicaltrials.gov/study/NCT04814082",
"title": "Prospective Functional, Gait, and Outcome Comparison Study of Medial Pivot",
"has_exemption": false,
"start_date": "2021-02-01",
"completion_date": "2030-07-01",
"has_results": false,
"results_due": false,
"sponsor_name": "LifeBridge Health",
"sponsor_slug": "lifebridge-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05564377",
"publication_url": "https://clinicaltrials.gov/study/NCT05564377",
"title": "Molecular Analysis for Combination Therapy Choice (ComboMATCH)",
"has_exemption": false,
"start_date": "2023-04-07",
"completion_date": "2030-07-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06692738",
"publication_url": "https://clinicaltrials.gov/study/NCT06692738",
"title": "A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab in Combination With Platinum-based Chemotherapy for the First-line Treatment of Patients With Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer Whose Tumors Express PD-L1 (ARTEMIDE-Lung02)",
"has_exemption": false,
"start_date": "2024-11-18",
"completion_date": "2030-07-01",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07121595",
"publication_url": "https://clinicaltrials.gov/study/NCT07121595",
"title": "PRECEDENT: Pilot Phase II Study of Personalized Radiation to the Contralateral Neck Directed by Sentinel Node Evaluation in Lateralized Oral Cavity Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2025-07-17",
"completion_date": "2030-07-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan Rogel Cancer Center",
"sponsor_slug": "university-of-michigan-rogel-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07519772",
"publication_url": "https://clinicaltrials.gov/study/NCT07519772",
"title": "A Phase 1b/2 Study to Evaluate the Safety and Efficacy of MK-1045 Monotherapy or in Combination With Other Anticancer Agents in Participants With Non-Hodgkin Lymphoma",
"has_exemption": false,
"start_date": "2026-05-03",
"completion_date": "2030-07-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07675174",
"publication_url": "https://clinicaltrials.gov/study/NCT07675174",
"title": "A Phase I-II Study of High-Dose Post-Transplant Cyclophosphamide, Bortezomib, and Abatacept for the Prevention of Graft-versus-Host Disease (GvHD) Following Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2030-07-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwell Health",
"sponsor_slug": "northwell-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07624305",
"publication_url": "https://clinicaltrials.gov/study/NCT07624305",
"title": "A Phase III, Randomised, Double-blind, Study to Evaluate the Effect of Balcinrenone/Dapagliflozin Compared With Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Chronic Kidney Disease (Stage 3b and 4)",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2030-07-01",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07464028",
"publication_url": "https://clinicaltrials.gov/study/NCT07464028",
"title": "Assessing Target Engagement for Terazosin in Parkinson's Disease (TZPD2)",
"has_exemption": false,
"start_date": "2028-07-01",
"completion_date": "2030-07-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Ergun Y. Uc",
"sponsor_slug": "ergun-y-uc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07683754",
"publication_url": "https://clinicaltrials.gov/study/NCT07683754",
"title": "A Global, Interventional, Open-label Trial of T-DXd-based Therapy Followed by Palbociclib, Endocrine Therapy and Dual HER2 Blockade in First-line HER2+/ HR+ Advanced or Metastatic Breast Cancer and Retreatment With T-DXd (DB-Guide)",
"has_exemption": false,
"start_date": "2026-09-18",
"completion_date": "2030-07-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Daiichi Sankyo",
"sponsor_slug": "daiichi-sankyo",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05459935",
"publication_url": "https://clinicaltrials.gov/study/NCT05459935",
"title": "Treatment of Pediatric Hypertrophic Tonsils and Pediatric Obstructive Sleep Apnea by Non-invasive Photobiomodulation",
"has_exemption": false,
"start_date": "2022-10-15",
"completion_date": "2030-07-06",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alberta",
"sponsor_slug": "university-of-alberta",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04715646",
"publication_url": "https://clinicaltrials.gov/study/NCT04715646",
"title": "Open-Label, Single-Arm, Multicenter Study to Evaluate Long-Term Safety and Tolerability of Brivaracetam Used as Adjunctive Treatment in Pediatric Study Participants With Epilepsy",
"has_exemption": false,
"start_date": "2021-03-11",
"completion_date": "2030-07-08",
"has_results": false,
"results_due": false,
"sponsor_name": "UCB Biopharma SRL",
"sponsor_slug": "ucb-biopharma-srl",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07559513",
"publication_url": "https://clinicaltrials.gov/study/NCT07559513",
"title": "Phase 3 Evaluation of the Safety, Pharmacokinetics, and Efficacy of Garetosmab (Anti-Activin A Monoclonal Antibody) in Children and Adolescents With Fibrodysplasia Ossificans Progressiva",
"has_exemption": false,
"start_date": "2027-02-02",
"completion_date": "2030-07-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04684602",
"publication_url": "https://clinicaltrials.gov/study/NCT04684602",
"title": "Evaluation of the Safety, Tolerability and Efficacy of Regenerative Therapy for the Treatment of Various Chronic and Acute Conditions",
"has_exemption": false,
"start_date": "2020-07-09",
"completion_date": "2030-07-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Thomas Advanced Medical LLC",
"sponsor_slug": "thomas-advanced-medical-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07789483",
"publication_url": "https://clinicaltrials.gov/study/NCT07789483",
"title": "An Open-Label Extension Study to Evaluate the Long-term Safety and Efficacy of ALXN2220 in Adult Participants With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)",
"has_exemption": false,
"start_date": "2027-11-23",
"completion_date": "2030-07-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Alexion Pharmaceuticals, Inc.",
"sponsor_slug": "alexion-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07146906",
"publication_url": "https://clinicaltrials.gov/study/NCT07146906",
"title": "An Open-label, Multicenter Study to Assess the Effect of Zigakibart Treatment on Histologic, Circulating, and Excreted Markers of Kidney Disease and Dysfunction in Adult Patients With IgA Nephropathy.",
"has_exemption": false,
"start_date": "2026-03-26",
"completion_date": "2030-07-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06054230",
"publication_url": "https://clinicaltrials.gov/study/NCT06054230",
"title": "Genomic Sequencing for Evaluation of Fetal Structural Anomalies",
"has_exemption": false,
"start_date": "2023-09-18",
"completion_date": "2030-07-15",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06678737",
"publication_url": "https://clinicaltrials.gov/study/NCT06678737",
"title": "CBIT+TMS R33 Phase",
"has_exemption": false,
"start_date": "2025-02-27",
"completion_date": "2030-07-15",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Minnesota",
"sponsor_slug": "university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07002216",
"publication_url": "https://clinicaltrials.gov/study/NCT07002216",
"title": "A Phase 2 Trial of Abbreviated Brentuximab Vedotin, Etoposide, Cyclophosphamide, Adriamycin, Dacarbazine, and Dexamethasone (BrECADD) Therapy in Stage 2 B-IV Hodgkin Lymphoma",
"has_exemption": false,
"start_date": "2025-07-15",
"completion_date": "2030-07-15",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Miami",
"sponsor_slug": "university-of-miami",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07220720",
"publication_url": "https://clinicaltrials.gov/study/NCT07220720",
"title": "Inclusion of POSLUMA® ((18)F-rhPSMA-7.3) PET-CT Imaging Improves Diagnostic Accuracy of Clinically-Significant Prostate Cancer Diagnosis in Men With PIRADS 2 and 3 Lesions on MRI",
"has_exemption": false,
"start_date": "2025-11-04",
"completion_date": "2030-07-15",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Florida",
"sponsor_slug": "university-of-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07751042",
"publication_url": "https://clinicaltrials.gov/study/NCT07751042",
"title": "A Phase 1/2, Open-label, Multi-center, First-in-human Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Antitumor Activity of STX-003 Delivered Intravenously in Patients With Advanced Solid Tumors as a Monotherapy or in Combination With Pembrolizumab",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2030-07-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Strand Therapeutics Inc.",
"sponsor_slug": "strand-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02543983",
"publication_url": "https://clinicaltrials.gov/study/NCT02543983",
"title": "The Neurobiology of Suicide",
"has_exemption": false,
"start_date": "2015-12-01",
"completion_date": "2030-07-21",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Mental Health (NIMH)",
"sponsor_slug": "national-institute-of-mental-health-nimh",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT05442216",
"publication_url": "https://clinicaltrials.gov/study/NCT05442216",
"title": "Phase II Study of TAGraxofusp and Azacitidine With Venetoclax in Newly Diagnosed Secondary AML After Previous Exposure to HypOmethylatiNG Agents",
"has_exemption": false,
"start_date": "2024-05-01",
"completion_date": "2030-07-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Joshua Zeidner",
"sponsor_slug": "joshua-zeidner",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07286266",
"publication_url": "https://clinicaltrials.gov/study/NCT07286266",
"title": "A Randomized, Open-label, Multicenter, Phase 3 Study to Investigate Mocertatug Rezetecan Compared With Standard of Care in Participants With Platinum-resistant Ovarian Cancer",
"has_exemption": false,
"start_date": "2026-06-18",
"completion_date": "2030-07-22",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07843472",
"publication_url": "https://clinicaltrials.gov/study/NCT07843472",
"title": "A Phase III, Randomized, Double-Blind, Placebo Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Once Weekly Petrelintide Vs. Placebo in Participants With Overweight Or Obesity And Established Cardiovascular Disease",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2030-07-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05895786",
"publication_url": "https://clinicaltrials.gov/study/NCT05895786",
"title": "A PHASE 3, MULTICENTER, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PF-06823859 IN PARTICIPANTS WITH ACTIVE IDIOPATHIC INFLAMMATORY MYOPATHIES (INCLUDING PARTICIPANTS WITH ACTIVE DERMATOMYOSITIS OR POLYMYOSITIS)",
"has_exemption": false,
"start_date": "2023-05-20",
"completion_date": "2030-07-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06022939",
"publication_url": "https://clinicaltrials.gov/study/NCT06022939",
"title": "A Phase III, Randomized Study of Daratumumab, Cyclophosphamide, Bortezomib and Dexamethasone (Dara-VCD) Induction Followed by Autologous Stem Cell Transplant or Dara-VCD Consolidation and Daratumumab Maintenance in Patients With Newly Diagnosed AL Amyloidosis",
"has_exemption": false,
"start_date": "2024-07-01",
"completion_date": "2030-07-29",
"has_results": false,
"results_due": false,
"sponsor_name": "SWOG Cancer Research Network",
"sponsor_slug": "swog-cancer-research-network",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07404826",
"publication_url": "https://clinicaltrials.gov/study/NCT07404826",
"title": "A Randomized, Sham Controlled Clinical Trial to Assess the Effectiveness of a Positive End Expiratory Device for Accelerating and Maintaining Pulmonary Rehabilitation Gains",
"has_exemption": false,
"start_date": "2026-07-16",
"completion_date": "2030-07-29",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06969755",
"publication_url": "https://clinicaltrials.gov/study/NCT06969755",
"title": "Biomarkers to Enhance Early Schizophrenia Treatment",
"has_exemption": false,
"start_date": "2024-09-04",
"completion_date": "2030-07-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwell Health",
"sponsor_slug": "northwell-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06561386",
"publication_url": "https://clinicaltrials.gov/study/NCT06561386",
"title": "A Phase 3, Randomized, Open-label Study of Nivolumab + Relatlimab Fixed-dose Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy as First-line Treatment for Participants With Non-squamous (NSQ), Stage IV or Recurrent Non-small Cell Lung Cancer and With Tumor Cell PD-L1 Expression ≥ 1%",
"has_exemption": false,
"start_date": "2024-10-07",
"completion_date": "2030-07-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06731413",
"publication_url": "https://clinicaltrials.gov/study/NCT06731413",
"title": "Phase 2 Study to Evaluate Reduced Dose Chemotherapy in Combination With Anti-PD-1 Therapy as First Line Treatment in Vulnerable or Older Adults (Vulnerable or Age ≥70) With Advanced PD-L1 TPS <50% Non-small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2025-02-11",
"completion_date": "2030-07-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Virginia Commonwealth University",
"sponsor_slug": "virginia-commonwealth-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07040566",
"publication_url": "https://clinicaltrials.gov/study/NCT07040566",
"title": "Investigating Efficacious E-Cigarette Interventions and Cessation Effects on Cancer-Related Biomarkers: A Randomized Trial of Varenicline in Adults",
"has_exemption": false,
"start_date": "2025-10-14",
"completion_date": "2030-07-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04373785",
"publication_url": "https://clinicaltrials.gov/study/NCT04373785",
"title": "A Multi-Center Pilot/Phase I and Phase II Clinical Trial of NG101m Adjuvant Therapy in Newly Diagnosed Glioblastoma Patients",
"has_exemption": false,
"start_date": "2027-01-01",
"completion_date": "2030-07-30",
"has_results": false,
"results_due": false,
"sponsor_name": "NeuGATE Theranostics",
"sponsor_slug": "neugate-theranostics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06716866",
"publication_url": "https://clinicaltrials.gov/study/NCT06716866",
"title": "Temporally Interfering Electric Field Stimulation in the Treatment of Epilepsy - Effect of Temporal Interference on Biomarkers of Epilepsy",
"has_exemption": false,
"start_date": "2019-01-16",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Davis",
"sponsor_slug": "university-of-california-davis",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04188535",
"publication_url": "https://clinicaltrials.gov/study/NCT04188535",
"title": "RELAY: Repeated Magnetic Resonance Imaging Examinations to Analyze and Assess Your Cancer: A Prospective Study on the Use of Serial Magnetic Resonance Imaging in the Assessment of Changes During Treatment With Radiation Therapy",
"has_exemption": false,
"start_date": "2020-01-15",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Dana-Farber Cancer Institute",
"sponsor_slug": "dana-farber-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04318717",
"publication_url": "https://clinicaltrials.gov/study/NCT04318717",
"title": "Adjuvant Pembrolizumab and Hypofractionated Radiation Therapy for the Treatment of Mucosal Melanoma",
"has_exemption": true,
"start_date": "2020-05-29",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04743141",
"publication_url": "https://clinicaltrials.gov/study/NCT04743141",
"title": "Phase 3, Multicenter, Open-label Study to Assess the Long-term Safety and Tolerability of Rimegepant for the Acute Treatment of Migraine (With or Without Aura) in Children and Adolescents ≥ 6 to < 18 Years of Age",
"has_exemption": false,
"start_date": "2021-04-28",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05145127",
"publication_url": "https://clinicaltrials.gov/study/NCT05145127",
"title": "AN OPEN-LABEL EXTENSION STUDY TO EVALUATE THE LONG-TERM SAFETY, TOLERABILITY, AND EFFICACY OF MARSTACIMAB PROPHYLAXIS IN SEVERE (COAGULATION FACTOR ACTIVITY <1%) HEMOPHILIA A PARTICIPANTS WITH OR WITHOUT INHIBITORS OR MODERATELY SEVERE TO SEVERE HEMOPHILIA B PARTICIPANTS (COAGULATION FACTOR ACTIVITY ≤2%) WITH OR WITHOUT INHIBITORS",
"has_exemption": false,
"start_date": "2021-11-17",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05469893",
"publication_url": "https://clinicaltrials.gov/study/NCT05469893",
"title": "Immuno-PRISM (PRecision Intervention Smoldering Myeloma): A Randomized Phase II Platform Study of Select Immunotherapies for High-Risk Smoldering Myeloma",
"has_exemption": false,
"start_date": "2022-08-10",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Irene Ghobrial, MD",
"sponsor_slug": "irene-ghobrial-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05131919",
"publication_url": "https://clinicaltrials.gov/study/NCT05131919",
"title": "Pembrolizumab for Locally Advanced, Irresectable, Non-metastatic dMMR Colorectal Cancers. The PUMA Study",
"has_exemption": false,
"start_date": "2022-12-22",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Netherlands Cancer Institute",
"sponsor_slug": "the-netherlands-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05768139",
"publication_url": "https://clinicaltrials.gov/study/NCT05768139",
"title": "First-in-Human Study of STX-478, a Mutant-Selective PI3Kα Inhibitor as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2023-04-17",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06072131",
"publication_url": "https://clinicaltrials.gov/study/NCT06072131",
"title": "A Phase 3, Randomized, Open-Label Study Comparing the Efficacy and Safety of the Combination of Beleodaq-CHOP or Folotyn-COP to the CHOP Regimen Alone in Newly Diagnosed Patients With Peripheral T-Cell Lymphoma",
"has_exemption": false,
"start_date": "2023-10-04",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Acrotech Biopharma Inc.",
"sponsor_slug": "acrotech-biopharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05821855",
"publication_url": "https://clinicaltrials.gov/study/NCT05821855",
"title": "A Postmarketing Study Evaluating the Effectiveness and Safety of the XEN45 Glaucoma Treatment System in Subjects With Open-Angle Glaucoma in China",
"has_exemption": false,
"start_date": "2024-01-09",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05828823",
"publication_url": "https://clinicaltrials.gov/study/NCT05828823",
"title": "Comparative Effectiveness of an Individualized Model of Hemodialysis Versus Conventional Hemodialysis",
"has_exemption": false,
"start_date": "2024-02-26",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06532656",
"publication_url": "https://clinicaltrials.gov/study/NCT06532656",
"title": "A Phase 2/3, Open-Label Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of Bictegravir/Lenacapavir in Children and Adolescents With HIV-1",
"has_exemption": false,
"start_date": "2024-11-20",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Gilead Sciences",
"sponsor_slug": "gilead-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07007273",
"publication_url": "https://clinicaltrials.gov/study/NCT07007273",
"title": "Pembrolizumab for Advanced Cutaneous Sarcomas Not Including Angiosarcoma",
"has_exemption": false,
"start_date": "2025-06-20",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06992440",
"publication_url": "https://clinicaltrials.gov/study/NCT06992440",
"title": "Empagliflozin to Improve Right Ventricular Function in Pulmonary Arterial Hypertension",
"has_exemption": false,
"start_date": "2025-06-26",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Gustavo A Heresi, MD, MS",
"sponsor_slug": "gustavo-a-heresi-md-ms",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06950385",
"publication_url": "https://clinicaltrials.gov/study/NCT06950385",
"title": "A Phase 3, Multi-Site, Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of eRapa to Improve Clinical Outcomes in Patients With Familial Adenomatous Polyposis",
"has_exemption": false,
"start_date": "2025-07-18",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Rapamycin Holdings Inc.",
"sponsor_slug": "rapamycin-holdings-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06596447",
"publication_url": "https://clinicaltrials.gov/study/NCT06596447",
"title": "Neurophysiological Investigation of the Approach-avoidance Axis in OCD: Applications to Neuromodulation",
"has_exemption": false,
"start_date": "2025-08-01",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Baylor College of Medicine",
"sponsor_slug": "baylor-college-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06912763",
"publication_url": "https://clinicaltrials.gov/study/NCT06912763",
"title": "Reversing External-beam Radiotherapy-associated Fibrosis Syndrome: an Interventional Bayesian Adaptive Randomized-controlled Orphan Drug Platform Trial for Orodental Sequelae (Reverse-fibrose)",
"has_exemption": false,
"start_date": "2025-08-08",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07276035",
"publication_url": "https://clinicaltrials.gov/study/NCT07276035",
"title": "TMS Neuromodulation of Brain-to-Stomach Circuits in Chronic Nausea",
"has_exemption": false,
"start_date": "2026-01-28",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "David Levinthal",
"sponsor_slug": "david-levinthal",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227584",
"publication_url": "https://clinicaltrials.gov/study/NCT07227584",
"title": "Treatment of Newly Diagnosed Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia in Adolescents and Young Adults (AYAs)",
"has_exemption": false,
"start_date": "2026-04-03",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Dana-Farber Cancer Institute",
"sponsor_slug": "dana-farber-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07225543",
"publication_url": "https://clinicaltrials.gov/study/NCT07225543",
"title": "Scavenging IsoLGs in Autoimmune Disease: a Proof-of-concept Clinical Study",
"has_exemption": false,
"start_date": "2026-05-15",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt University Medical Center",
"sponsor_slug": "vanderbilt-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07176546",
"publication_url": "https://clinicaltrials.gov/study/NCT07176546",
"title": "TAVNEOS for Otolaryngologic Manifestations of Granulomatosis With Polyangiitis",
"has_exemption": false,
"start_date": "2026-05-22",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Robert Spiera, MD",
"sponsor_slug": "robert-spiera-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06915233",
"publication_url": "https://clinicaltrials.gov/study/NCT06915233",
"title": "A Prospective, Open-label, Randomized, Concurrent Active-controlled, Longitudinal, Multicenter, Phase 3 Clinical Study of the Safety and Efficacy of MACI in Patients With Symptomatic Chondral or Osteochondral Lesions of the Talus (MASCOT)",
"has_exemption": false,
"start_date": "2026-05-28",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vericel Corporation",
"sponsor_slug": "vericel-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07211802",
"publication_url": "https://clinicaltrials.gov/study/NCT07211802",
"title": "Utilizing Continuous Ketone Monitors to Enable Safe Use of SGLT Inhibitors in Patients With Type 1 Diabetes",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07470606",
"publication_url": "https://clinicaltrials.gov/study/NCT07470606",
"title": "Memory RT: Memantine +/- Raloxifene for Cognitive Preservation After Radiation Therapy to the Brain",
"has_exemption": false,
"start_date": "2026-07-06",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center at San Antonio",
"sponsor_slug": "the-university-of-texas-health-science-center-at-san-antonio",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07610369",
"publication_url": "https://clinicaltrials.gov/study/NCT07610369",
"title": "The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease",
"has_exemption": false,
"start_date": "2026-07-10",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07281768",
"publication_url": "https://clinicaltrials.gov/study/NCT07281768",
"title": "Combining Capecitabine/Oxaliplatin Chemotherapy With Cemiplimab Alone or in Combination With Fianlimab or REGN7075 for the Neoadjuvant Treatment of Locally Advanced Rectal Cancer",
"has_exemption": false,
"start_date": "2026-07-14",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
"sponsor_slug": "sidney-kimmel-comprehensive-cancer-center-at-johns-hopkins",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07556237",
"publication_url": "https://clinicaltrials.gov/study/NCT07556237",
"title": "Gastric Electrical Stimulation for Abdominal Pain in Patients With Gastroparesis",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Louisville",
"sponsor_slug": "university-of-louisville",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07770685",
"publication_url": "https://clinicaltrials.gov/study/NCT07770685",
"title": "A Phase 1, Multicenter, Open-Label, Ascending-Dose and Phase 2, Randomized, Double-Masked, Sham-Controlled, Clinical Study to Evaluate the Safety and Efficacy of ASP2767 in Participants With Optic Neuropathy Due to Glaucoma",
"has_exemption": false,
"start_date": "2026-08-14",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Astellas Pharma Global Development, Inc.",
"sponsor_slug": "astellas-pharma-global-development-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07733466",
"publication_url": "https://clinicaltrials.gov/study/NCT07733466",
"title": "Neoadjuvant Pembrolizumab Plus Cetuximab in Betel Nut-Associated Locally Advanced Oral Cavity Squamous Cell Carcinoma in the Commonwealth of the Northern Mariana Islands: A Prospective, Open Label, Single Arm, Single Center, Non-randomized, Phase 2 Trial",
"has_exemption": false,
"start_date": "2026-08-15",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Peter Brett, MD",
"sponsor_slug": "peter-brett-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07733908",
"publication_url": "https://clinicaltrials.gov/study/NCT07733908",
"title": "Efficacy of Posluma PET Scan in Evaulation and Monitoring of Patients Undergoing Focal Therapy for Prostate Cancer",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Aditya Bagrodia",
"sponsor_slug": "aditya-bagrodia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07739966",
"publication_url": "https://clinicaltrials.gov/study/NCT07739966",
"title": "A Phase 1b/2, Multicenter, 2-part, Open-label Trial to Evaluate DS-3939a in Participants With Solid Tumors",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Daiichi Sankyo",
"sponsor_slug": "daiichi-sankyo",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07849114",
"publication_url": "https://clinicaltrials.gov/study/NCT07849114",
"title": "Deep Brain Stimulation of the Motor Thalamus Combined With Speech and Swallowing Therapy to Improve Post-Stroke Motor Speech and Swallowing Production Impairments",
"has_exemption": false,
"start_date": "2027-01-31",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Pirondini, Elvira, PhD",
"sponsor_slug": "pirondini-elvira-phd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07137481",
"publication_url": "https://clinicaltrials.gov/study/NCT07137481",
"title": "Phase II Study of CD5 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Aggressive T Cell Hematological Malignancies",
"has_exemption": false,
"start_date": "2027-02-28",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07583641",
"publication_url": "https://clinicaltrials.gov/study/NCT07583641",
"title": "A Global, Multicenter, Randomized, Double-Blinded, Placebo-Controlled, Phase 2 Study to Evaluate the Efficacy, Safety, and Tolerability of Efgartigimod PH20 SC in Adult and Adolescent Participants With Autoimmune Encephalitis",
"has_exemption": false,
"start_date": "2027-04-01",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "argenx",
"sponsor_slug": "argenx",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02129751",
"publication_url": "https://clinicaltrials.gov/study/NCT02129751",
"title": "A Double-Blind, Placebo-Controlled, Multicenter Study of Efficacy and Safety of Bupropion Hydrobromide in Adolescents and Children With Major Depressive Disorder",
"has_exemption": false,
"start_date": "2027-07-01",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Bausch Health Americas, Inc.",
"sponsor_slug": "bausch-health-americas-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07793461",
"publication_url": "https://clinicaltrials.gov/study/NCT07793461",
"title": "Gastrointestinal Dopamine Decarboxylase and Levodopa Pharmacokinetics",
"has_exemption": false,
"start_date": "2027-07-31",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Beth Israel Deaconess Medical Center",
"sponsor_slug": "beth-israel-deaconess-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06443177",
"publication_url": "https://clinicaltrials.gov/study/NCT06443177",
"title": "The Effect of Sympathetic Modulation on Cerebral Vasospasm Secondary to Aneurysmal Subarachnoid Hemorrhage",
"has_exemption": false,
"start_date": "2028-07-31",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07215013",
"publication_url": "https://clinicaltrials.gov/study/NCT07215013",
"title": "Acoustic Resonance Therapy for Treatment of Empty Nose Syndrome: A Prospective, Phase 2 Randomized Clinical Trial",
"has_exemption": false,
"start_date": "2028-07-31",
"completion_date": "2030-07-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05737693",
"publication_url": "https://clinicaltrials.gov/study/NCT05737693",
"title": "Posttraumatic Stress Disorder (PTSD) Treatment: Using Ketamine to Enhance Memory Reconsolidation and Extinction of Overgeneralized Fear in Individuals Diagnosed With PTSD",
"has_exemption": false,
"start_date": "2023-08-21",
"completion_date": "2030-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06467344",
"publication_url": "https://clinicaltrials.gov/study/NCT06467344",
"title": "ACDN-01-001: Open-Label, Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Subretinal ACDN-01 in Participants With ABCA4-related Retinopathy",
"has_exemption": false,
"start_date": "2024-06-11",
"completion_date": "2030-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Ascidian Therapeutics, Inc",
"sponsor_slug": "ascidian-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06843551",
"publication_url": "https://clinicaltrials.gov/study/NCT06843551",
"title": "A Phase 2 Single Arm Trial of Stereotactic Body Radiation Therapy Followed by Dual Immune Checkpoint Inhibition for Patients With Metastatic Pancreatic Ductal Adenocarcinoma - The Miami \"EMPIRE\" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation",
"has_exemption": false,
"start_date": "2025-06-18",
"completion_date": "2030-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Benjamin Spieler",
"sponsor_slug": "benjamin-spieler",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07516132",
"publication_url": "https://clinicaltrials.gov/study/NCT07516132",
"title": "A Phase 3b, Multicenter, Open-Label, Extension Study to Evaluate Long-Term Safety of Intravitreal OTX-TKI (Axitinib Implant) in Participants With Neovascular Age-Related Macular Degeneration Who Successfully Completed 2-Year OTX-TKI-2023-AMD-301 or OTX-TKI-2023-AMD-303 Study",
"has_exemption": false,
"start_date": "2026-04-27",
"completion_date": "2030-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Ocular Therapeutix, Inc.",
"sponsor_slug": "ocular-therapeutix-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06976840",
"publication_url": "https://clinicaltrials.gov/study/NCT06976840",
"title": "Rapid Antidepressant Dynamics in Acute Neuromodulation Treatments",
"has_exemption": false,
"start_date": "2026-05-15",
"completion_date": "2030-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Marta Peciña MD PhD",
"sponsor_slug": "marta-pecina-md-phd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06732388",
"publication_url": "https://clinicaltrials.gov/study/NCT06732388",
"title": "Repurposing Itraconazole for Secondary Prevention of Metaplasia and Primary Prevention of Cancer in Patients With High-risk Barrett's Esophagus in Combination With Ablation",
"has_exemption": false,
"start_date": "2026-06-23",
"completion_date": "2030-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07277595",
"publication_url": "https://clinicaltrials.gov/study/NCT07277595",
"title": "KTMP: A Novel Method of Non-invasive Brain Stimulation to Enhance Motor Function in Chronic Stroke Patients.",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2030-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07532252",
"publication_url": "https://clinicaltrials.gov/study/NCT07532252",
"title": "A Double-Blind Randomized Controlled Trial of Daridorexant for Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2027-01-01",
"completion_date": "2030-08-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04047628",
"publication_url": "https://clinicaltrials.gov/study/NCT04047628",
"title": "A Multicenter Randomized Controlled Trial of Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Treatment-Resistant Relapsing Multiple Sclerosis (ITN077AI)",
"has_exemption": false,
"start_date": "2020-08-17",
"completion_date": "2030-08-06",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Allergy and Infectious Diseases (NIAID)",
"sponsor_slug": "national-institute-of-allergy-and-infectious-diseases-niaid",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04976322",
"publication_url": "https://clinicaltrials.gov/study/NCT04976322",
"title": "A Multicenter, Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of Dapirolizumab Pegol Treatment in Study Participants With Systemic Lupus Erythematosus",
"has_exemption": false,
"start_date": "2021-07-27",
"completion_date": "2030-08-07",
"has_results": false,
"results_due": false,
"sponsor_name": "UCB Biopharma SRL",
"sponsor_slug": "ucb-biopharma-srl",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04300556",
"publication_url": "https://clinicaltrials.gov/study/NCT04300556",
"title": "A Multicenter, Open-Label Phase 1/2 Trial Evaluating the Safety, Tolerability, and Efficacy of MORAb-202, a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Subjects With Selected Tumor Types",
"has_exemption": false,
"start_date": "2020-08-06",
"completion_date": "2030-08-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Eisai Inc.",
"sponsor_slug": "eisai-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07768436",
"publication_url": "https://clinicaltrials.gov/study/NCT07768436",
"title": "STUDY OF DOSE DENSE CMF (Cyclophosphamide, Methotrexate, Fluorouracil) as an Alternative to AC (Doxorubicin, Cyclophosphamide) in 2 Regimens in EARLY STAGE BREAST CANCER for Patients Greater or Equal to 70",
"has_exemption": false,
"start_date": "2026-08-11",
"completion_date": "2030-08-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06405087",
"publication_url": "https://clinicaltrials.gov/study/NCT06405087",
"title": "A Phase 3b Extension Study to Evaluate the Long-term Safety of Vedolizumab Subcutaneous in Pediatric Subjects With Ulcerative Colitis or Crohn's Disease",
"has_exemption": false,
"start_date": "2025-10-27",
"completion_date": "2030-08-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04579224",
"publication_url": "https://clinicaltrials.gov/study/NCT04579224",
"title": "A Phase III Randomized Trial of Eribulin (NSC #707389) With Gemcitabine Versus Standard of Care (Physician's Choice) for Treatment of Metastatic Urothelial Carcinoma Refractory to, or Ineligible for, Anti PD1/PDL1 Therapy",
"has_exemption": false,
"start_date": "2021-06-28",
"completion_date": "2030-08-15",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06683755",
"publication_url": "https://clinicaltrials.gov/study/NCT06683755",
"title": "Phase I/IIa Dose Finding Study of Triplet Regimen of Relatlimab Ipilimumab and NIvolumab in First Line Therapy of Metastatic Melanoma (TRINITY)",
"has_exemption": false,
"start_date": "2024-12-31",
"completion_date": "2030-08-16",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07436728",
"publication_url": "https://clinicaltrials.gov/study/NCT07436728",
"title": "A Phase 1/2 First-in-Human, Open-Label, Dose Escalation and Expansion Trial of TAK-505 Monotherapy in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2026-05-11",
"completion_date": "2030-08-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07851259",
"publication_url": "https://clinicaltrials.gov/study/NCT07851259",
"title": "A Phase II, Randomized, Double-Masked, Placebo-Controlled Multicenter Study to Assess the Efficacy and Safety of RO7965032 in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2030-08-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Genentech, Inc.",
"sponsor_slug": "genentech-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05983276",
"publication_url": "https://clinicaltrials.gov/study/NCT05983276",
"title": "Combination of the Hypomethylating Agent Decitabine and the Nuclear Export Receptor XPO-1 Inhibitor Selinexor to Reverse Platinum Resistance in Relapsed/Refractory Epithelial Ovarian Cancer",
"has_exemption": false,
"start_date": "2023-11-16",
"completion_date": "2030-08-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Loyola University",
"sponsor_slug": "loyola-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04877522",
"publication_url": "https://clinicaltrials.gov/study/NCT04877522",
"title": "An Open Label, Multi-center Asciminib Roll-over Study to Assess Long-term Safety in Patients Who Have Completed a Novartis Sponsored Asciminib Study and Are Judged by the Investigator to Benefit From Continued Treatment",
"has_exemption": false,
"start_date": "2022-08-30",
"completion_date": "2030-08-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05451004",
"publication_url": "https://clinicaltrials.gov/study/NCT05451004",
"title": "SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer. A Phase III Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2023-02-10",
"completion_date": "2030-08-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Canadian Cancer Trials Group",
"sponsor_slug": "canadian-cancer-trials-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07154706",
"publication_url": "https://clinicaltrials.gov/study/NCT07154706",
"title": "A Phase 3 Multicenter Double-blind Randomized Study of Taletrectinib Versus Placebo in Patients With ROS1-Fusion Positive Stage IB-IIIA Non-Small Cell Lung Cancer Who Have Undergone Complete Tumor Resection",
"has_exemption": false,
"start_date": "2025-08-21",
"completion_date": "2030-08-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Nuvation Bio, Inc.",
"sponsor_slug": "nuvation-bio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227311",
"publication_url": "https://clinicaltrials.gov/study/NCT07227311",
"title": "A Phase 2, Multicenter, Open Label, Non-randomized Study to Evaluate the Efficacy and Safety of Extended Dosing of Belantamab Mafodotin in Different Combinations With Standard of Care Regimens in Participants With Relapsed-refractory Multiple Myeloma (DREAMM-15)",
"has_exemption": false,
"start_date": "2026-04-15",
"completion_date": "2030-08-30",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07652515",
"publication_url": "https://clinicaltrials.gov/study/NCT07652515",
"title": "Phase 4, Open Label, Single-arm, Interventional, Multicenter Study to Evaluate the Safety of Dostarlimab in Adult Patients in India With Primary Advanced or Recurrent Endometrial Cancer",
"has_exemption": false,
"start_date": "2026-08-17",
"completion_date": "2030-08-30",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07079111",
"publication_url": "https://clinicaltrials.gov/study/NCT07079111",
"title": "3D Printed Occlusal Splints for Intraoperative Use",
"has_exemption": false,
"start_date": "2026-12-30",
"completion_date": "2030-08-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03396276",
"publication_url": "https://clinicaltrials.gov/study/NCT03396276",
"title": "Houston Emergency Opioid Engagement System (HEROES)",
"has_exemption": false,
"start_date": "2018-04-01",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03942328",
"publication_url": "https://clinicaltrials.gov/study/NCT03942328",
"title": "MC1641 Phase II Study Of Intratumoral Injection Of Autologous Dendritic Cells Combined With Immune Checkpoint Inhibition After High-Dose Conformal External Beam Radiotherapy In Patients With Unresectable Primary Liver Cancer",
"has_exemption": false,
"start_date": "2019-09-19",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04110730",
"publication_url": "https://clinicaltrials.gov/study/NCT04110730",
"title": "The Influence of 3D Printed Prostheses on Neural Activation Patterns of the Primary Motor Cortex in Children With Unilateral Congenital Upper-limb Reductions",
"has_exemption": false,
"start_date": "2020-01-10",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Nebraska",
"sponsor_slug": "university-of-nebraska",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04811014",
"publication_url": "https://clinicaltrials.gov/study/NCT04811014",
"title": "Houston Emergency Engagement System for Youths and Adolescents",
"has_exemption": false,
"start_date": "2021-04-19",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05092451",
"publication_url": "https://clinicaltrials.gov/study/NCT05092451",
"title": "Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances",
"has_exemption": false,
"start_date": "2022-11-01",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06051617",
"publication_url": "https://clinicaltrials.gov/study/NCT06051617",
"title": "AFFIRM: A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effect of Seladelpar on Clinical Outcomes in Patients With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis",
"has_exemption": false,
"start_date": "2023-09-07",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Gilead Sciences",
"sponsor_slug": "gilead-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06431893",
"publication_url": "https://clinicaltrials.gov/study/NCT06431893",
"title": "An Open-Label, Phase 3 Long-Term Extension (LTE) Study To Assess The Safety, Tolerability, And Efficacy Of Treatment With Pegtibatinase In Participants With Classical Homocystinuria (HCU) Due To Cystathionine Beta Synthase Deficiency (ENSEMBLE)",
"has_exemption": false,
"start_date": "2024-04-30",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Travere Therapeutics, Inc.",
"sponsor_slug": "travere-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07219485",
"publication_url": "https://clinicaltrials.gov/study/NCT07219485",
"title": "An Open-Label Study to Evaluate Safety of Pitolisant in Participants With Prader-Willi Syndrome",
"has_exemption": false,
"start_date": "2025-08-20",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Harmony Biosciences Management, Inc.",
"sponsor_slug": "harmony-biosciences-management-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06948019",
"publication_url": "https://clinicaltrials.gov/study/NCT06948019",
"title": "Safety and Efficacy of AAV9/AP4B1 For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47): A Phase 1/2 Single-Center, Open-Label Study of Stereotactic Intra-cisterna Magna Administration",
"has_exemption": false,
"start_date": "2025-08-31",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "BlackfinBio Ltd",
"sponsor_slug": "blackfinbio-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07185256",
"publication_url": "https://clinicaltrials.gov/study/NCT07185256",
"title": "A Phase 1b/2a, Open-Label, Dose-Exploration Basket Study to Investigate the Safety and Tolerability of Subretinally Injected OPGx-BEST1 Administered in Patients With Either Autosomal-Dominant BEST1 Disease (Best Vitelliform Macular Dystrophy [BVMD]) or Autosomal-Recessive Bestrophinopathy (ARB)",
"has_exemption": false,
"start_date": "2025-09-25",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Opus Genetics, Inc",
"sponsor_slug": "opus-genetics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07165028",
"publication_url": "https://clinicaltrials.gov/study/NCT07165028",
"title": "A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes",
"has_exemption": false,
"start_date": "2025-10-15",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07303738",
"publication_url": "https://clinicaltrials.gov/study/NCT07303738",
"title": "The Use of High Bile-Binding Foods to Reduce Upper Gastrointestinal Bile Acid Concentrations: A Novel Intervention for Children at Risk for Aspiration-Associated Complications (Aim 1)",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Children’s Hospital",
"sponsor_slug": "boston-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07096297",
"publication_url": "https://clinicaltrials.gov/study/NCT07096297",
"title": "A Phase II Study of Luspatercept Plus Darbepoetin Alfa in Non-mutated SF3B1 Lower-risk Myelodysplastic Syndromes",
"has_exemption": false,
"start_date": "2025-12-16",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07397559",
"publication_url": "https://clinicaltrials.gov/study/NCT07397559",
"title": "Spatiotemporal Control of Transcutaneous Spinal Cord Stimulation for Motor Function in SCI",
"has_exemption": false,
"start_date": "2026-01-19",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07022405",
"publication_url": "https://clinicaltrials.gov/study/NCT07022405",
"title": "Stratified Pharmacological Approaches for Regulating Circuit-Level Effects Study",
"has_exemption": false,
"start_date": "2026-01-23",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07029529",
"publication_url": "https://clinicaltrials.gov/study/NCT07029529",
"title": "Phase 2 Study of Apremilast in Women and Men With Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2026-05-12",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07434492",
"publication_url": "https://clinicaltrials.gov/study/NCT07434492",
"title": "Smart Ankle-Foot Orthosis and 5-Azacitidine to Enhance Gait and Community Mobility for Children With Cerebral Palsy",
"has_exemption": false,
"start_date": "2026-05-28",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Shirley Ryan AbilityLab",
"sponsor_slug": "shirley-ryan-abilitylab",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07598643",
"publication_url": "https://clinicaltrials.gov/study/NCT07598643",
"title": "Modulation of the Immune System in Down Syndrome for Improved Outcomes and Neurodevelopment - 1",
"has_exemption": false,
"start_date": "2026-05-28",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07450677",
"publication_url": "https://clinicaltrials.gov/study/NCT07450677",
"title": "Neurobehavioral Effects of Visual Assistive Technologies",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07695701",
"publication_url": "https://clinicaltrials.gov/study/NCT07695701",
"title": "An Open-Label Study to Investigate the Long-Term Effects of Acoramidis on Cardiac Function, Structure and Cardiac Amyloid Burden in Participants With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2030-08-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eidos Therapeutics, a BridgeBio company",
"sponsor_slug": "eidos-therapeutics-a-bridgebio-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
}
]
}