HTTP 200 OK
Allow: GET, POST, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"recordsFiltered": 47012,
"recordsTotal": 47012,
"next": "http://fdaaa.trialstracker.net/api/trials/?format=api&length=300&ordering=-days_late&start=43500",
"previous": "http://fdaaa.trialstracker.net/api/trials/?format=api&length=300&ordering=-days_late&start=42900",
"results": [
{
"registry_id": "NCT06478212",
"publication_url": "https://clinicaltrials.gov/study/NCT06478212",
"title": "A Phase 1b/2, Multicenter Study of Vorasidenib in Combination With Temozolomide (TMZ) in Participants With IDH1- or IDH2-mutant Glioma",
"has_exemption": false,
"start_date": "2025-01-22",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Institut de Recherches Internationales Servier",
"sponsor_slug": "institut-de-recherches-internationales-servier",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06908226",
"publication_url": "https://clinicaltrials.gov/study/NCT06908226",
"title": "A Phase 3, Open-Label Study to Investigate the Long-Term Safety and Efficacy of LP352 in the Treatment of Seizures in Children and Adults With Developmental and Epileptic Encephalopathy",
"has_exemption": false,
"start_date": "2025-02-12",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Longboard Pharmaceuticals",
"sponsor_slug": "longboard-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06533163",
"publication_url": "https://clinicaltrials.gov/study/NCT06533163",
"title": "Low-Intensity Oscillatory Magnetic Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme (GBM) - An Exposure-time Escalation Pilot Trial",
"has_exemption": false,
"start_date": "2025-02-17",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "BioTex, Inc.",
"sponsor_slug": "biotex-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05670951",
"publication_url": "https://clinicaltrials.gov/study/NCT05670951",
"title": "A Multi-center, Double-Blind, Randomized, Two-Arm, Parallel-Group, Placebo Controlled Study to Assess the Efficacy and Safety of ELGN-2112 on Intestinal Malabsorption in Preterm Infants",
"has_exemption": false,
"start_date": "2025-02-20",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Elgan Pharma Ltd.",
"sponsor_slug": "elgan-pharma-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06712823",
"publication_url": "https://clinicaltrials.gov/study/NCT06712823",
"title": "An Open-label, Long-term Extension Study to Evaluate Safety and Efficacy in Participants Treated With CRN04894",
"has_exemption": false,
"start_date": "2025-02-25",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Crinetics Pharmaceuticals Inc.",
"sponsor_slug": "crinetics-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06523621",
"publication_url": "https://clinicaltrials.gov/study/NCT06523621",
"title": "Nivolumab As An Adjunctive Therapy In Relapsed Refractory Multiple Myeloma Patients With Sub-Optimal Response To Idecabtagene Vicleucel",
"has_exemption": false,
"start_date": "2025-02-28",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06772623",
"publication_url": "https://clinicaltrials.gov/study/NCT06772623",
"title": "An Open-label Multi-Cohort Phase 1b/2 Study to Evaluate the Safety, Efficacy, and Optimal Dose of Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease and No Actionable Genomic Alterations",
"has_exemption": false,
"start_date": "2025-03-06",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06864026",
"publication_url": "https://clinicaltrials.gov/study/NCT06864026",
"title": "A Phase 4, Prospective, Open-Label, Single-Arm Study to Assess the Effectiveness of Tirzepatide After Initiation of Ixekizumab in Adult Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice.",
"has_exemption": false,
"start_date": "2025-03-06",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07040059",
"publication_url": "https://clinicaltrials.gov/study/NCT07040059",
"title": "A Phase 1b/2, Open-label, Randomized, Multicenter Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of AUR103 Calcium in Patients With HER2-positive Advanced Gastric/Gastroesophageal Junction Adenocarcinoma (BHARAT-2)",
"has_exemption": false,
"start_date": "2025-03-22",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Aurigene Discovery Technologies Limited",
"sponsor_slug": "aurigene-discovery-technologies-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06809140",
"publication_url": "https://clinicaltrials.gov/study/NCT06809140",
"title": "Phase 2 Trial of Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of Muscle-invasive Urothelial Cancer of the Bladder",
"has_exemption": false,
"start_date": "2025-04-07",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Matthew Galsky",
"sponsor_slug": "matthew-galsky",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06920043",
"publication_url": "https://clinicaltrials.gov/study/NCT06920043",
"title": "A Phase 2, Randomized, Double-blinded, Placebo-controlled Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to Metabolic Dysfunction-associated Steatohepatitis (MASH)",
"has_exemption": false,
"start_date": "2025-04-09",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Pharmaceuticals",
"sponsor_slug": "boston-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06953869",
"publication_url": "https://clinicaltrials.gov/study/NCT06953869",
"title": "A Multicenter, Double-Blind, Randomized Study to Evaluate the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia",
"has_exemption": false,
"start_date": "2025-04-21",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanda Pharmaceuticals",
"sponsor_slug": "vanda-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06961968",
"publication_url": "https://clinicaltrials.gov/study/NCT06961968",
"title": "A Multicenter, Double-Blind, Randomized Withdrawal Study in Patients With Schizophrenia Receiving Either Iloperidone Long-Acting Injection (LAI) or Placebo Injection",
"has_exemption": false,
"start_date": "2025-05-14",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanda Pharmaceuticals",
"sponsor_slug": "vanda-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06973564",
"publication_url": "https://clinicaltrials.gov/study/NCT06973564",
"title": "A Phase 1/2a, Multicenter, Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-tumor Activity of JAB-23E73 in Adult Patients With Advanced Solid Tumors With KRAS Alteration",
"has_exemption": false,
"start_date": "2025-05-29",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Jacobio Pharmaceuticals Co., Ltd.",
"sponsor_slug": "jacobio-pharmaceuticals-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07023731",
"publication_url": "https://clinicaltrials.gov/study/NCT07023731",
"title": "A Phase 1/2 Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of ARV-806 in Participants With KRAS G12D Mutated Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2025-05-29",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Arvinas Inc",
"sponsor_slug": "arvinas-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06891443",
"publication_url": "https://clinicaltrials.gov/study/NCT06891443",
"title": "A Double-Masked, Randomized, Placebo-Controlled, Paired-Eye Study to Evaluate the Efficacy, Safety and Tolerability of Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Due to the c.2991+1655A>G (p.Cys998X) Mutation in the CEP290 Gene",
"has_exemption": false,
"start_date": "2025-06-04",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Laboratoires Thea",
"sponsor_slug": "laboratoires-thea",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06303869",
"publication_url": "https://clinicaltrials.gov/study/NCT06303869",
"title": "Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke",
"has_exemption": false,
"start_date": "2025-06-20",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Jorge Gonzalez-Martinez",
"sponsor_slug": "jorge-gonzalez-martinez",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06628128",
"publication_url": "https://clinicaltrials.gov/study/NCT06628128",
"title": "An Open-Label Extension Study to Evaluate the Long-Term Safety and Efficacy of JNT-517 in Participants With Phenylketonuria",
"has_exemption": false,
"start_date": "2025-06-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Otsuka Pharmaceutical Development & Commercialization, Inc.",
"sponsor_slug": "otsuka-pharmaceutical-development-commercialization-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06145763",
"publication_url": "https://clinicaltrials.gov/study/NCT06145763",
"title": "Digital Smoking Cessation Intervention for Nationally-Recruited American Indians and Alaska Natives: A Full-Scale Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2025-07-03",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06983028",
"publication_url": "https://clinicaltrials.gov/study/NCT06983028",
"title": "A Phase 2 Study to Evaluate the Safety and Efficacy of Atacicept in Multiple Autoimmune Glomerular Diseases (PIONEER)",
"has_exemption": false,
"start_date": "2025-07-07",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Vera Therapeutics, Inc.",
"sponsor_slug": "vera-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07105098",
"publication_url": "https://clinicaltrials.gov/study/NCT07105098",
"title": "A Global, Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of NBI-1117568 in Adults With Schizophrenia Who Warrant Inpatient Hospitalization",
"has_exemption": false,
"start_date": "2025-08-11",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Neurocrine Biosciences",
"sponsor_slug": "neurocrine-biosciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07101614",
"publication_url": "https://clinicaltrials.gov/study/NCT07101614",
"title": "An Open-label, Randomized, Multi-center, Multi-cohort Clinical Study of JS004 and Toripalimab Combined With Chemotherapy vs Toripalimab Combined With Chemotherapy vs Chemotherapy Alone as Neoadjuvant Therapy for Stage II-III Triple-negative Breast Cancer (TNBC).",
"has_exemption": false,
"start_date": "2025-09-01",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Shengjing Hospital",
"sponsor_slug": "shengjing-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06247241",
"publication_url": "https://clinicaltrials.gov/study/NCT06247241",
"title": "A Phase 2a, Open-Label, First-In-Human, Two-Part, Single And Multiple Ascending Dose Study To Evaluate The Safety, Tolerability, And Efficacy Of VMB-100 In Female Subjects With Moderate Stress Urinary Incontinence",
"has_exemption": false,
"start_date": "2025-09-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Versameb AG",
"sponsor_slug": "versameb-ag",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07078383",
"publication_url": "https://clinicaltrials.gov/study/NCT07078383",
"title": "Evaluation of the Rapidlink Device for Use in the Repair or Replacement of the Supra-Aortic Vessels During an Open Surgical Procedure of the Thoracic Aorta",
"has_exemption": false,
"start_date": "2025-09-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Vascutek Ltd.",
"sponsor_slug": "vascutek-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07131722",
"publication_url": "https://clinicaltrials.gov/study/NCT07131722",
"title": "An Open-Label, Dose-Finding, Phase 1/2a Study to Evaluate the Efficacy and Safety of PRG-N-01 in Patients With Neurofibromatosis Type II",
"has_exemption": false,
"start_date": "2025-10-31",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "PRG Science & Technology Co., Ltd.",
"sponsor_slug": "prg-science-technology-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07187531",
"publication_url": "https://clinicaltrials.gov/study/NCT07187531",
"title": "A Phase 2b, Randomised, Double-Blind, Placebo-Controlled, Parallel-Arm Dose Finding Study Evaluating the Efficacy and Safety of SAB-142 for Delaying the Progression of Type 1 Diabetes (T1D) in Patients With Stage 3 New Onset of Type 1 Diabetes (NOT1D)",
"has_exemption": false,
"start_date": "2025-10-31",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "SAb Biotherapeutics, Inc.",
"sponsor_slug": "sab-biotherapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06728423",
"publication_url": "https://clinicaltrials.gov/study/NCT06728423",
"title": "SmartGuard vs Temp Target in Patients With Type 1 Diabetes Users AHCL in Anaerobic Exercise",
"has_exemption": false,
"start_date": "2025-11-01",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Hospital Universitario San Ignacio",
"sponsor_slug": "hospital-universitario-san-ignacio",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07128342",
"publication_url": "https://clinicaltrials.gov/study/NCT07128342",
"title": "Use of Continuous Glucose Monitoring in Veterans With Uncontrolled Diabetes Managed Without Insulin Therapy",
"has_exemption": false,
"start_date": "2025-11-01",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Milwaukee VA Medical Center",
"sponsor_slug": "milwaukee-va-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07139977",
"publication_url": "https://clinicaltrials.gov/study/NCT07139977",
"title": "Open-Label Phase II Trial of Enfortumab Vedotin in Recurrent or Persistent Endometrial Carcinoma",
"has_exemption": false,
"start_date": "2025-11-01",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "William Bradley",
"sponsor_slug": "william-bradley",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07190807",
"publication_url": "https://clinicaltrials.gov/study/NCT07190807",
"title": "Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control (MOSAIC Study)",
"has_exemption": false,
"start_date": "2025-11-07",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Scientific Corporation",
"sponsor_slug": "boston-scientific-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07243119",
"publication_url": "https://clinicaltrials.gov/study/NCT07243119",
"title": "PRedicting Recovery of Left Ventricular Function With Multimodality Cardiac IMAging in Patients With de Novo Heart Failure",
"has_exemption": false,
"start_date": "2025-11-24",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Gødstrup Hospital",
"sponsor_slug": "gdstrup-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07142291",
"publication_url": "https://clinicaltrials.gov/study/NCT07142291",
"title": "A Phase IIB Randomized, Double-Blind, Placebo-Controlled, Multi-Dose Study to Evaluate the Effects of PHENOGENE-1A (Cromolyn) as an Adjuvant Treatment in Subjects With Mild to Moderate Amyotrophic Lateral Sclerosis (ALS)",
"has_exemption": false,
"start_date": "2025-11-25",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "PhenoNet, Inc.",
"sponsor_slug": "phenonet-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07062588",
"publication_url": "https://clinicaltrials.gov/study/NCT07062588",
"title": "A Phase 2, Multi-center, Randomized, Double-blind, Placebo-controlled, Dose-ranging Study to Evaluate the Safety and Efficacy of AGA2115 in Adults With Type I, III, or IV Osteogenesis Imperfecta (OI)",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Angitia Incorporated Limited",
"sponsor_slug": "angitia-incorporated-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07115329",
"publication_url": "https://clinicaltrials.gov/study/NCT07115329",
"title": "Phase 2, Multicenter, Randomized, Double-Blind Evaluation of the Efficacy and Safety of Oral GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Syndeio Biosciences, Inc",
"sponsor_slug": "syndeio-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07171346",
"publication_url": "https://clinicaltrials.gov/study/NCT07171346",
"title": "Effects on Patient Outcomes With Post-Operative Use of Zynex Neuromuscular Electrical Stimulation (NMES): Zynex-25",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Kansas Medical Center",
"sponsor_slug": "university-of-kansas-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07209215",
"publication_url": "https://clinicaltrials.gov/study/NCT07209215",
"title": "ULtra sensiTive ctDNA-Informed Management eArly-stage recTal cancEr (ULTIMATE)",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Davis",
"sponsor_slug": "university-of-california-davis",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07203092",
"publication_url": "https://clinicaltrials.gov/study/NCT07203092",
"title": "Effects of Transcranial Photobiomodulation on Cognition and Brain Metabolism in Adults With ADHD",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas at Austin",
"sponsor_slug": "university-of-texas-at-austin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07216443",
"publication_url": "https://clinicaltrials.gov/study/NCT07216443",
"title": "A Phase 2 Trial in Patients With Acute Myelogenous Leukemia and Myelodysplastic Syndrome Undergoing Reduced Intensity or Non-myeloablative Allogeneic Hematopoietic Cell Transplantation With Orca-T",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Orca Biosystems, Inc.",
"sponsor_slug": "orca-biosystems-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07208760",
"publication_url": "https://clinicaltrials.gov/study/NCT07208760",
"title": "A Phase 2, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Effect of L9LS on R21/Matrix-M™ Vaccine Immunogenicity",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Allergy and Infectious Diseases (NIAID)",
"sponsor_slug": "national-institute-of-allergy-and-infectious-diseases-niaid",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07206602",
"publication_url": "https://clinicaltrials.gov/study/NCT07206602",
"title": "A Pilot Study Assessing Outcomes Of Artificial Intelligence-Guided Left Bundle Branch Area Pacing For Cardiac Resynchronization In Heart Failure",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07220473",
"publication_url": "https://clinicaltrials.gov/study/NCT07220473",
"title": "The Moody Longevity Trial: Tirzepatide to Slow Biological Aging",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Medical Branch, Galveston",
"sponsor_slug": "the-university-of-texas-medical-branch-galveston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07221760",
"publication_url": "https://clinicaltrials.gov/study/NCT07221760",
"title": "An Open-label Single Center, Single Participant Study of an Experimental Antisense Oligonucleotide Treatment for Dentatorubral-pallidoluysian Atrophy (DRPLA) Due to ATN1 Mutation",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "n-Lorem Foundation",
"sponsor_slug": "n-lorem-foundation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07222410",
"publication_url": "https://clinicaltrials.gov/study/NCT07222410",
"title": "Closed Loop Oxygen Control in COPD Patients Treated With Nasal High Flow in the Hospital",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Fisher and Paykel Healthcare",
"sponsor_slug": "fisher-and-paykel-healthcare",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227792",
"publication_url": "https://clinicaltrials.gov/study/NCT07227792",
"title": "Tongue-out Radiation Therapy (TORT) for the Mitigation of Radiotherapy-related Toxicities in Patients With Head and Neck Cancer",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Yvonne Mowery",
"sponsor_slug": "yvonne-mowery",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07245641",
"publication_url": "https://clinicaltrials.gov/study/NCT07245641",
"title": "Targeted Accelerated TMS for Post-Traumatic Stress Disorder",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06664814",
"publication_url": "https://clinicaltrials.gov/study/NCT06664814",
"title": "An Open-Label Phase 2 Study of N-Acetyl-D-Mannosamine (ManNAc) in Subjects With Primary Focal Segmental Glomerulosclerosis",
"has_exemption": false,
"start_date": "2025-12-09",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Human Genome Research Institute (NHGRI)",
"sponsor_slug": "national-human-genome-research-institute-nhgri",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06817889",
"publication_url": "https://clinicaltrials.gov/study/NCT06817889",
"title": "An Open-Label Study to Assess the Safety and Efficacy of Remdesivir for Treatment of Symptomatic Laboratory-Confirmed Respiratory Syncytial Virus Infection of the Upper Respiratory Tract in Patients Receiving Cellular or Bispecific Antibody Therapies",
"has_exemption": false,
"start_date": "2025-12-17",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07228741",
"publication_url": "https://clinicaltrials.gov/study/NCT07228741",
"title": "Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity",
"has_exemption": false,
"start_date": "2025-12-31",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "St. Jude Children's Research Hospital",
"sponsor_slug": "st-jude-childrens-research-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06528691",
"publication_url": "https://clinicaltrials.gov/study/NCT06528691",
"title": "PHASE 2 Study of Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors (GLOBOTRK)",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "St. Jude Children's Research Hospital",
"sponsor_slug": "st-jude-childrens-research-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07222202",
"publication_url": "https://clinicaltrials.gov/study/NCT07222202",
"title": "A Noninvasive, Flexible Conductive Hearing Aid With Micro-epidermal Actuators on Pediatric and Adult Patients",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06696755",
"publication_url": "https://clinicaltrials.gov/study/NCT06696755",
"title": "A Phase 2, Multicenter, 6-Week, Double Blind, Placebo- Controlled Study to Evaluate the Efficacy and Safety of Icalcaprant in Subjects With Bipolar Depression",
"has_exemption": false,
"start_date": "2026-02-05",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07257120",
"publication_url": "https://clinicaltrials.gov/study/NCT07257120",
"title": "A Phase IV, Open-label, Single-group Study Evaluating KarXT Concentrations in the Breast Milk and Plasma of Healthy Lactating Female Participants",
"has_exemption": false,
"start_date": "2026-04-14",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Karuna Therapeutics",
"sponsor_slug": "karuna-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06887738",
"publication_url": "https://clinicaltrials.gov/study/NCT06887738",
"title": "A Proof-of-Concept Phase II, Open-Label Study of NM8074 in Patients with Dermatomyositis (DM)",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "NovelMed Therapeutics",
"sponsor_slug": "novelmed-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02669251",
"publication_url": "https://clinicaltrials.gov/study/NCT02669251",
"title": "A Phase 1b/2 Study of Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation",
"has_exemption": false,
"start_date": "2016-04-28",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03619551",
"publication_url": "https://clinicaltrials.gov/study/NCT03619551",
"title": "A Randomized Trial of Low Versus Moderate Exposure Busulfan for Infants With Severe Combined Immunodeficiency (SCID) Receiving TCRαβ+/CD19+ Depleted Transplantation: A Phase II Study by the Primary Immune Deficiency Treatment Consortium (PIDTC) and Pediatric Blood and Marrow Transplant Consortium (PBMTC)",
"has_exemption": false,
"start_date": "2018-10-22",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Center for International Blood and Marrow Transplant Research",
"sponsor_slug": "center-for-international-blood-and-marrow-transplant-research",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03759028",
"publication_url": "https://clinicaltrials.gov/study/NCT03759028",
"title": "A Randomized Controlled Trial of Acetaminophen and Ibuprofen Versus Acetaminophen and Oxycodone for Postoperative Pain Control in Operative Pediatric Supracondylar Humerus Fracture",
"has_exemption": false,
"start_date": "2019-02-26",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Los Angeles",
"sponsor_slug": "university-of-california-los-angeles",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03745326",
"publication_url": "https://clinicaltrials.gov/study/NCT03745326",
"title": "A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients",
"has_exemption": false,
"start_date": "2019-05-16",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04671771",
"publication_url": "https://clinicaltrials.gov/study/NCT04671771",
"title": "A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease",
"has_exemption": false,
"start_date": "2020-12-03",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "W.L.Gore & Associates",
"sponsor_slug": "wlgore-associates",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04821739",
"publication_url": "https://clinicaltrials.gov/study/NCT04821739",
"title": "A Prospective Multi-Center Study of the AGN1 Local Osteo-Enhancement Procedure (LOEP) SV Kit in Patients With Vertebral Compression Fractures (VCFs)",
"has_exemption": false,
"start_date": "2021-05-19",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "AgNovos Healthcare, LLC",
"sponsor_slug": "agnovos-healthcare-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05863754",
"publication_url": "https://clinicaltrials.gov/study/NCT05863754",
"title": "Grasp-Release Assessment of a Networked Neuroprosthesis Device",
"has_exemption": false,
"start_date": "2022-01-23",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "MetroHealth Medical Center",
"sponsor_slug": "metrohealth-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05342883",
"publication_url": "https://clinicaltrials.gov/study/NCT05342883",
"title": "Pilot Study of Resection and GammaTile Followed by Concomitant External Beam Radiation Therapy (EBRT) and Temozolomide (TMZ) and Adjuvant in Newly Diagnosed Glioblastoma (GBM)",
"has_exemption": false,
"start_date": "2022-08-17",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "GT Medical Technologies, Inc.",
"sponsor_slug": "gt-medical-technologies-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05154669",
"publication_url": "https://clinicaltrials.gov/study/NCT05154669",
"title": "Integrating Financial Coaching and Smoking Cessation Coaching for People With Low Income Who Smoke: a Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2022-12-08",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05437705",
"publication_url": "https://clinicaltrials.gov/study/NCT05437705",
"title": "Decoding and Modulating Affective Brain States",
"has_exemption": false,
"start_date": "2023-02-21",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05795101",
"publication_url": "https://clinicaltrials.gov/study/NCT05795101",
"title": "TRUDI: A Phase II Study of Neoadjuvant Trastuzumab Deruxtecan and Durvalumab for Stage III, HER2-expressing Inflammatory Breast Cancer",
"has_exemption": false,
"start_date": "2023-05-04",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Filipa Lynce, MD",
"sponsor_slug": "filipa-lynce-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05303519",
"publication_url": "https://clinicaltrials.gov/study/NCT05303519",
"title": "A Phase 2, Multicenter, Clinical Study to Evaluate the Efficacy and Safety of Safusidenib Erbumine in Patients With Isocitrate Dehydrogenase 1 (IDH1) Mutant Glioma",
"has_exemption": false,
"start_date": "2023-06-05",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Nuvation Bio, Inc.",
"sponsor_slug": "nuvation-bio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06047353",
"publication_url": "https://clinicaltrials.gov/study/NCT06047353",
"title": "Community Health Advocates for Motivating PAP Use in Our Neighborhoods.",
"has_exemption": false,
"start_date": "2023-09-29",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Miami",
"sponsor_slug": "university-of-miami",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05616650",
"publication_url": "https://clinicaltrials.gov/study/NCT05616650",
"title": "A Phase II Trial of Focal Ultrahypofractionated Stereotactic Radiation Therapy for the Treatment of Unifocal Prostate Cancer",
"has_exemption": false,
"start_date": "2023-10-19",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05561127",
"publication_url": "https://clinicaltrials.gov/study/NCT05561127",
"title": "Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel",
"has_exemption": false,
"start_date": "2023-11-01",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "GIE Medical",
"sponsor_slug": "gie-medical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06072963",
"publication_url": "https://clinicaltrials.gov/study/NCT06072963",
"title": "Combination of Intranasal Insulin With Oral Semaglutide to Improve Cognition and Cerebral Blood Flow: a Feasibility Study",
"has_exemption": false,
"start_date": "2024-01-30",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Rutgers, The State University of New Jersey",
"sponsor_slug": "rutgers-the-state-university-of-new-jersey",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06091085",
"publication_url": "https://clinicaltrials.gov/study/NCT06091085",
"title": "Acetazolamide as a Means to Mitigate Falling Ventilatory Drive and Drive-dependent OSA",
"has_exemption": false,
"start_date": "2024-01-31",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06110130",
"publication_url": "https://clinicaltrials.gov/study/NCT06110130",
"title": "Effect of Empagliflozin on Podocyte Specific Proteins (Injury Markers) in African American Veterans With Non-Diabetic Chronic Kidney Disease",
"has_exemption": false,
"start_date": "2024-02-02",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington D.C. Veterans Affairs Medical Center",
"sponsor_slug": "washington-dc-veterans-affairs-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06223360",
"publication_url": "https://clinicaltrials.gov/study/NCT06223360",
"title": "A Seamless Phase 2A-Phase 2B Randomized Double-Blind Placebo- Controlled Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam)",
"has_exemption": false,
"start_date": "2024-03-28",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Alzheimer's Disease Cooperative Study (ADCS)",
"sponsor_slug": "alzheimers-disease-cooperative-study-adcs",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06270316",
"publication_url": "https://clinicaltrials.gov/study/NCT06270316",
"title": "A Phase 1/2, Single Dose, Dose Ranging Study of Intravenous AAV5-GLA (AMT-191) in Adult Males With Classic Fabry Disease",
"has_exemption": false,
"start_date": "2024-06-05",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "UniQure Biopharma B.V.",
"sponsor_slug": "uniqure-biopharma-bv",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05775471",
"publication_url": "https://clinicaltrials.gov/study/NCT05775471",
"title": "Neoadjuvant Combination Pembrolizumab / Enfortumab Vedotin With Adjuvant Pembrolizumab Prior to and After Radical Nephroureterectomy for High-Risk Upper Tract Urothelial Carcinoma",
"has_exemption": false,
"start_date": "2024-06-26",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonsson Comprehensive Cancer Center",
"sponsor_slug": "jonsson-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06308952",
"publication_url": "https://clinicaltrials.gov/study/NCT06308952",
"title": "Atorvastatin Pretreatment in Cerebrovascular Events (APICES) After Flow Diverter Implantation: Protocol of a Multicenter, Randomized, Double-blind, Placebo-controlled Clinical Trial",
"has_exemption": false,
"start_date": "2024-07-30",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Duan Chuanzhi",
"sponsor_slug": "duan-chuanzhi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05733598",
"publication_url": "https://clinicaltrials.gov/study/NCT05733598",
"title": "A Phase 2, Open-label, Multicenter Study Investigating RP2 Oncolytic Immunotherapy in Combination With Second-line Therapy in Patients With Locally Advanced Unresectable, Recurrent and/or Metastatic Hepatocellular Carcinoma",
"has_exemption": false,
"start_date": "2024-08-01",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Replimune Inc.",
"sponsor_slug": "replimune-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05827159",
"publication_url": "https://clinicaltrials.gov/study/NCT05827159",
"title": "Emergency Department-Initiated Medications for Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2024-08-17",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06246357",
"publication_url": "https://clinicaltrials.gov/study/NCT06246357",
"title": "Phase 2 Study Evaluating the Functional Status of the Adrenal Glands With [68Ga]Ga-PentixaFor in Hyperaldosteronism and Hypercortisolism",
"has_exemption": false,
"start_date": "2024-09-23",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06496256",
"publication_url": "https://clinicaltrials.gov/study/NCT06496256",
"title": "Randomized Trial of Barrigel® to Increase Distance Between the Rectum and Prostate Bed to Decrease Rectal Dose in Patients Receiving Moderately Hypofractionated Radiation Therapy Who Have Had Recurrence of Prostate Cancer After Prostatectomy",
"has_exemption": false,
"start_date": "2024-10-31",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Palette Life Sciences, Inc.",
"sponsor_slug": "palette-life-sciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05654103",
"publication_url": "https://clinicaltrials.gov/study/NCT05654103",
"title": "Randomized Controlled Trial Comparing endoAVF Versus surgAVF",
"has_exemption": false,
"start_date": "2024-11-20",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Los Angeles",
"sponsor_slug": "university-of-california-los-angeles",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06607432",
"publication_url": "https://clinicaltrials.gov/study/NCT06607432",
"title": "Use of Alpha-frequency Deep Transcranial Interference Stimulation (tIS) to Understand and Modify Temporal Dynamics of Face Emotion Recognition and Social/Affective Function",
"has_exemption": false,
"start_date": "2025-03-03",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Columbia University",
"sponsor_slug": "columbia-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06548230",
"publication_url": "https://clinicaltrials.gov/study/NCT06548230",
"title": "A Phase 1B/2A Trial of NADUNOLIMAB in Combination With Azacitidine (With/Without Venetoclax) in Patients With Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML)",
"has_exemption": false,
"start_date": "2025-03-05",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06929806",
"publication_url": "https://clinicaltrials.gov/study/NCT06929806",
"title": "A Phase III, Randomized, Open-label, Blinded Endpoint, Comparative Trial of Ferric Derisomaltose Versus no Intravenous Iron in Iron-deficient Subjects With Symptomatic Chronic Heart Failure",
"has_exemption": false,
"start_date": "2025-05-01",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Pharmacosmos A/S",
"sponsor_slug": "pharmacosmos-as",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06958289",
"publication_url": "https://clinicaltrials.gov/study/NCT06958289",
"title": "Cryoneurolysis for Spasticity Treatment: Quantifying Long-term Clinical Outcomes and Exploring Mechanisms Within the Central Nervous System",
"has_exemption": false,
"start_date": "2025-05-01",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Sue Peters",
"sponsor_slug": "sue-peters",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06881784",
"publication_url": "https://clinicaltrials.gov/study/NCT06881784",
"title": "RASolve 301: Phase 3 Multicenter, Open Label, Randomized Study of RMC-6236 Versus Docetaxel in Patients With Previously Treated Locally Advanced or Metastatic RAS[MUT] NSCLC",
"has_exemption": false,
"start_date": "2025-05-06",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Revolution Medicines, Inc.",
"sponsor_slug": "revolution-medicines-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05999383",
"publication_url": "https://clinicaltrials.gov/study/NCT05999383",
"title": "Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration",
"has_exemption": false,
"start_date": "2025-07-01",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06424977",
"publication_url": "https://clinicaltrials.gov/study/NCT06424977",
"title": "Safety and Effectiveness of Biomarker Targeted Stimulation in Epilepsy",
"has_exemption": false,
"start_date": "2025-09-01",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Cadence Neuroscience",
"sponsor_slug": "cadence-neuroscience",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06847399",
"publication_url": "https://clinicaltrials.gov/study/NCT06847399",
"title": "Efficacy and Safety of Tirzepatide Versus Placebo or Lisdexamfetamine Dimesylate for Binge-Eating Disorder: A Randomized Clinical Trial",
"has_exemption": false,
"start_date": "2025-09-17",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06552000",
"publication_url": "https://clinicaltrials.gov/study/NCT06552000",
"title": "Phase 0 Trial of Pre-operative Tumor Treating Fields in Patients With Resectable Lung Cancer",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07158021",
"publication_url": "https://clinicaltrials.gov/study/NCT07158021",
"title": "Phase 2 Randomized Trial to Examine Ovarian Function Suppression for Breast Cancer (OFS)",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan Rogel Cancer Center",
"sponsor_slug": "university-of-michigan-rogel-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07213466",
"publication_url": "https://clinicaltrials.gov/study/NCT07213466",
"title": "Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder - OBOE-Mayo",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07215949",
"publication_url": "https://clinicaltrials.gov/study/NCT07215949",
"title": "Zilucoplan Treatment of Severe MG Exacerbations Leading to Hospitalization of Participants With Acetylcholine Receptor Antibody Positive gMG",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Miriam Freimer",
"sponsor_slug": "miriam-freimer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07224893",
"publication_url": "https://clinicaltrials.gov/study/NCT07224893",
"title": "Once-Daily Versus Twice-Daily Insulin Glargine in the Management of Patients With Pregestational Diabetes Requiring Insulin",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Eastern Virginia Medical School",
"sponsor_slug": "eastern-virginia-medical-school",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07246005",
"publication_url": "https://clinicaltrials.gov/study/NCT07246005",
"title": "A Randomised Pilot Study Assessing the Optimal Duration of Anticoagulation for Left Ventricular Thrombus",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Queen Mary University of London",
"sponsor_slug": "queen-mary-university-of-london",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07249346",
"publication_url": "https://clinicaltrials.gov/study/NCT07249346",
"title": "An Open Label, Non-Randomized, Multi-Center Pilot Dose-Expansion Study of Low Dose Post-Transplant Cyclophosphamide/Tacrolimus/Ruxolitinib for GVHD Prophylaxis in Myeloablative Allogeneic Peripheral Blood Stem Cell Transplantation",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Hannah Choe, MD",
"sponsor_slug": "hannah-choe-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06654050",
"publication_url": "https://clinicaltrials.gov/study/NCT06654050",
"title": "Phase II Study of Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma",
"has_exemption": false,
"start_date": "2025-12-09",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06648473",
"publication_url": "https://clinicaltrials.gov/study/NCT06648473",
"title": "Repeatability of Magnetic Resonance Imaging in Patients With IDH1 Mutant Glioma on Ivosidenib",
"has_exemption": false,
"start_date": "2026-01-01",
"completion_date": "2027-12-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Duke University",
"sponsor_slug": "duke-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT01964859",
"publication_url": "https://clinicaltrials.gov/study/NCT01964859",
"title": "Feasibility Study for Fibroblast Autologous Skin Grafts: Biopsy of Skin Fibroblasts, Expansion in Cell Therapy Core, Topical Injection of Fibroblasts, and Subsequent Removal of Graft for Laboratory Studies.",
"has_exemption": false,
"start_date": "2015-01-07",
"completion_date": "2027-12-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT06798012",
"publication_url": "https://clinicaltrials.gov/study/NCT06798012",
"title": "A Phase 2, Open-label, Proof-of-Concept Study to Investigate the Efficacy, Safety, and Tolerability of TAK-411 in Adult Subjects With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (The CASCA Study)",
"has_exemption": false,
"start_date": "2025-05-14",
"completion_date": "2027-12-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07048743",
"publication_url": "https://clinicaltrials.gov/study/NCT07048743",
"title": "Psilocybin-assisted Existential, Attachment and Relational (PEARL) Therapy for Caregivers of Patients With Advanced Cancer: A Phase II Open-Label Trial",
"has_exemption": false,
"start_date": "2025-07-02",
"completion_date": "2027-12-02",
"has_results": false,
"results_due": false,
"sponsor_name": "University Health Network, Toronto",
"sponsor_slug": "university-health-network-toronto",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07158918",
"publication_url": "https://clinicaltrials.gov/study/NCT07158918",
"title": "A Multicenter, Open-label, Phase 1b/2 Trial of ABL103, a Bispecific Antibody of B7-H4 and 4-1BB, in Combination With Pembrolizumab With/Without Taxane in Subjects With Selected, Progressive, Locally Advanced (Unresectable) or Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2025-08-06",
"completion_date": "2027-12-02",
"has_results": false,
"results_due": false,
"sponsor_name": "ABL Bio, Inc.",
"sponsor_slug": "abl-bio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07041281",
"publication_url": "https://clinicaltrials.gov/study/NCT07041281",
"title": "Spironolactone to Improve Pregnancy-Associated Hypertension Trajectories",
"has_exemption": false,
"start_date": "2025-10-16",
"completion_date": "2027-12-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07076186",
"publication_url": "https://clinicaltrials.gov/study/NCT07076186",
"title": "Phase II Decentralized Pragmatic Trial of Adjuvant Doxorubicin - Trabectedin Chemotherapy in Uterine Leiomyosarcoma",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2027-12-02",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05467748",
"publication_url": "https://clinicaltrials.gov/study/NCT05467748",
"title": "Phase Ib/II Study of Safety and Efficacy of EZH2 Inhibitor, Tulmimetostat, and PD-1 Blockade for Treatment of Advanced Non-small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2025-12-02",
"completion_date": "2027-12-02",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06795412",
"publication_url": "https://clinicaltrials.gov/study/NCT06795412",
"title": "A Phase 1/2, Open-label, Global, Multicenter, Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of PYX-201 in Combination With Pembrolizumab in Participants With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2025-04-15",
"completion_date": "2027-12-06",
"has_results": false,
"results_due": false,
"sponsor_name": "Pyxis Oncology, Inc",
"sponsor_slug": "pyxis-oncology-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07088926",
"publication_url": "https://clinicaltrials.gov/study/NCT07088926",
"title": "A Phase IIb Randomized, Double-blind, Placebo-controlled, Parallel, Multidose Study to Evaluate the Efficacy, Safety, and PK of AZD0292 in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization",
"has_exemption": false,
"start_date": "2025-11-06",
"completion_date": "2027-12-09",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05758493",
"publication_url": "https://clinicaltrials.gov/study/NCT05758493",
"title": "Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosis",
"has_exemption": false,
"start_date": "2023-01-10",
"completion_date": "2027-12-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Oregon Health and Science University",
"sponsor_slug": "oregon-health-and-science-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06736613",
"publication_url": "https://clinicaltrials.gov/study/NCT06736613",
"title": "Cerebral Spinal Fluid Circulating Tumor DNA (ctDNA) Analysis in Patients With Aggressive B-cell Lymphoma Receiving Front Line Therapy and at High Risk for Central Nervous System Relapse",
"has_exemption": false,
"start_date": "2024-12-11",
"completion_date": "2027-12-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05631249",
"publication_url": "https://clinicaltrials.gov/study/NCT05631249",
"title": "An Interventional and Translational Study Investigating Sotorasib in Previously Treated Locally Advanced or Metastatic NSCLC Subjects With Mutated KRAS p.G12C",
"has_exemption": false,
"start_date": "2022-12-13",
"completion_date": "2027-12-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Gustave Roussy, Cancer Campus, Grand Paris",
"sponsor_slug": "gustave-roussy-cancer-campus-grand-paris",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05511246",
"publication_url": "https://clinicaltrials.gov/study/NCT05511246",
"title": "Venous Ethanol for Ischemic Left Ventricular Tachycardia",
"has_exemption": false,
"start_date": "2023-04-12",
"completion_date": "2027-12-12",
"has_results": false,
"results_due": false,
"sponsor_name": "The Methodist Hospital Research Institute",
"sponsor_slug": "the-methodist-hospital-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07172919",
"publication_url": "https://clinicaltrials.gov/study/NCT07172919",
"title": "A Rollover Study of Sotorasib With or Without Panitumumab for the Treatment of Cancer Subjects With KRAS p.G12C Mutation Previously Treated in an Amgen-Sponsored Study",
"has_exemption": false,
"start_date": "2025-12-12",
"completion_date": "2027-12-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Amgen",
"sponsor_slug": "amgen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06084884",
"publication_url": "https://clinicaltrials.gov/study/NCT06084884",
"title": "A Phase I/II Open-Label Study to Evaluate the Safety, Cellular Kinetics and Efficacy of AZD5851, a Chimeric Antigen Receptor T-Cell (CAR-T) Therapy Directed Against GPC3 in Adult Participants With Advanced/Recurrent Hepatocellular Carcinoma: ATHENA",
"has_exemption": false,
"start_date": "2023-12-14",
"completion_date": "2027-12-13",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06890884",
"publication_url": "https://clinicaltrials.gov/study/NCT06890884",
"title": "A Randomized, Open-label, Multicenter, Phase 2 Study Evaluating the Efficacy and Safety of Zilovertamab Vedotin (MK-2140) Plus R-CHP Versus Polatuzumab Vedotin Plus R-CHP in Treatment-naïve Participants With GCB Subtype of Diffuse Large B-cell Lymphoma (DLBCL)",
"has_exemption": false,
"start_date": "2025-04-11",
"completion_date": "2027-12-13",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06533644",
"publication_url": "https://clinicaltrials.gov/study/NCT06533644",
"title": "A Phase 2a Multicenter, Dose-Escalation and Dose Optimization Study of SYNC-T Therapy SV-102 for Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC)",
"has_exemption": false,
"start_date": "2025-05-29",
"completion_date": "2027-12-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Syncromune, Inc.",
"sponsor_slug": "syncromune-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04065399",
"publication_url": "https://clinicaltrials.gov/study/NCT04065399",
"title": "A Phase 1/2, Open-label, Dose-Escalation and Dose-Expansion Cohort Study of SNDX-5613 in Patients With Relapsed/Refractory Leukemias, Including Those Harboring an MLL/KMT2A Gene Rearrangement or Nucleophosmin 1 (NPM1) Mutation",
"has_exemption": false,
"start_date": "2019-11-05",
"completion_date": "2027-12-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Syndax Pharmaceuticals",
"sponsor_slug": "syndax-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05063552",
"publication_url": "https://clinicaltrials.gov/study/NCT05063552",
"title": "A Phase II/III Trial of Chemotherapy + Cetuximab vs Chemotherapy + Bevacizumab vs Atezolizumab + Bevacizumab Following Progression on Immune Checkpoint Inhibition in Recurrent/Metastatic Head and Neck Cancers",
"has_exemption": false,
"start_date": "2023-03-13",
"completion_date": "2027-12-15",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06472245",
"publication_url": "https://clinicaltrials.gov/study/NCT06472245",
"title": "A Randomised, Open-label, Phase 3 Trial Comparing the Efficacy and Safety of OSE2101 Versus Docetaxel in HLA-A2 Positive Patients With Metastatic Non-Small Cell Lung Cancer (NSCLC) With Secondary Resistance to Immune Checkpoint Inhibitor",
"has_exemption": false,
"start_date": "2024-12-03",
"completion_date": "2027-12-15",
"has_results": false,
"results_due": false,
"sponsor_name": "OSE Immunotherapeutics",
"sponsor_slug": "ose-immunotherapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06750094",
"publication_url": "https://clinicaltrials.gov/study/NCT06750094",
"title": "A Randomized, Open-label Phase 3 Study of Amivantamab + FOLFIRI Versus Cetuximab/Bevacizumab + FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Recurrent, Unresectable or Metastatic Colorectal Cancer Who Have Received Prior Chemotherapy",
"has_exemption": false,
"start_date": "2024-12-12",
"completion_date": "2027-12-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06657209",
"publication_url": "https://clinicaltrials.gov/study/NCT06657209",
"title": "Normal-weight Diabetes: Adipocyte-directed Therapy with Pioglitazone or Tirzepatide",
"has_exemption": false,
"start_date": "2024-12-15",
"completion_date": "2027-12-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06533098",
"publication_url": "https://clinicaltrials.gov/study/NCT06533098",
"title": "Multicenter, Open-Label, Randomized Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)",
"has_exemption": false,
"start_date": "2025-02-10",
"completion_date": "2027-12-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06765980",
"publication_url": "https://clinicaltrials.gov/study/NCT06765980",
"title": "A Phase 1/2, First-in-Human, Multi-Arm, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Efficacy of an Adeno-associated Virus Vector VV-14295 Administered Suprachoroidally With the Everads Injector In AdultS With GeographIc Atrophy Secondary to Age-related Macular DegeneratiON (the VISION Study)",
"has_exemption": false,
"start_date": "2025-05-28",
"completion_date": "2027-12-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Kriya Therapeutics, Inc.",
"sponsor_slug": "kriya-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07220382",
"publication_url": "https://clinicaltrials.gov/study/NCT07220382",
"title": "PREoperative Targeted OnabotulinumtoXina Injection for Abdominal Wall Reconstruction: A Randomized, Double-Blind, Placebo-Controlled Trial",
"has_exemption": false,
"start_date": "2025-11-03",
"completion_date": "2027-12-15",
"has_results": false,
"results_due": false,
"sponsor_name": "The Cleveland Clinic",
"sponsor_slug": "the-cleveland-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07223723",
"publication_url": "https://clinicaltrials.gov/study/NCT07223723",
"title": "A Multicenter, Open-Label, Postmarketing Surveillance Study of Tofersen (BIIB067) in Adults With Amyotrophic Lateral Sclerosis (ALS) Associated With a Mutation in the Superoxide Dismutase 1 (SOD1) Gene in China",
"has_exemption": false,
"start_date": "2025-12-02",
"completion_date": "2027-12-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Biogen",
"sponsor_slug": "biogen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06796907",
"publication_url": "https://clinicaltrials.gov/study/NCT06796907",
"title": "A Phase I/II Randomized Multi-Cohort Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 in Combination With Anti-Cancer Agents in Participants With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2025-03-04",
"completion_date": "2027-12-17",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04895358",
"publication_url": "https://clinicaltrials.gov/study/NCT04895358",
"title": "A Randomized, Double-blind, Placebo-controlled, Phase 3 Study of Pembrolizumab Plus Chemotherapy Versus Placebo Plus Chemotherapy for the Treatment of Chemotherapy-Candidate Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (HR+/HER2-) Locally Recurrent Inoperable or Metastatic Breast Cancer (KEYNOTE-B49)",
"has_exemption": false,
"start_date": "2021-06-18",
"completion_date": "2027-12-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07115134",
"publication_url": "https://clinicaltrials.gov/study/NCT07115134",
"title": "Efficacy of a Novel Prototype Gastrostomy Tube Anchor Dressing",
"has_exemption": false,
"start_date": "2024-09-24",
"completion_date": "2027-12-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's National Research Institute",
"sponsor_slug": "childrens-national-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03778996",
"publication_url": "https://clinicaltrials.gov/study/NCT03778996",
"title": "Phase 2 Clinical Trial to Evaluate Efficacy and Safety of SM-88 Used With Methoxsalen, Phenytoin, and Sirolimus (MPS) as Maintenance Therapy Following Standard Treatments for Ewing's Sarcoma or as Salvage Therapy for Advanced Sarcomas",
"has_exemption": false,
"start_date": "2020-01-03",
"completion_date": "2027-12-19",
"has_results": false,
"results_due": false,
"sponsor_name": "Sarcoma Oncology Research Center, LLC",
"sponsor_slug": "sarcoma-oncology-research-center-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04375332",
"publication_url": "https://clinicaltrials.gov/study/NCT04375332",
"title": "A Prospective, Multi-center Trial to Evaluate the Safety and Effectiveness of Beating Heart Mitral Valve Repair With the HARPOON™ System (RESTORE)",
"has_exemption": false,
"start_date": "2020-12-16",
"completion_date": "2027-12-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Edwards Lifesciences",
"sponsor_slug": "edwards-lifesciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05382338",
"publication_url": "https://clinicaltrials.gov/study/NCT05382338",
"title": "A Phase 3 Study of Sodium Thiosulfate for Reduction of Cisplatin-Induced Ototoxicity in Children With Average-Risk Medulloblastoma and Reduced Therapy in Children With Medulloblastoma With Low-Risk Features",
"has_exemption": false,
"start_date": "2023-02-20",
"completion_date": "2027-12-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07061951",
"publication_url": "https://clinicaltrials.gov/study/NCT07061951",
"title": "A Phase 2 Pilot Study of Mirdametinib in Relapsed Refractory Chronic Lymphocytic Leukemia",
"has_exemption": false,
"start_date": "2025-10-31",
"completion_date": "2027-12-20",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06752356",
"publication_url": "https://clinicaltrials.gov/study/NCT06752356",
"title": "A Double-blind, Randomized, Multi-Center Study Investigating Efficacy and Safety of Two Different Dosages of Intravenous Human Normal Immune Globulin (IGIV) 10% in Subjects With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-12-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Kedrion S.p.A.",
"sponsor_slug": "kedrion-spa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04452591",
"publication_url": "https://clinicaltrials.gov/study/NCT04452591",
"title": "A Phase 3 Study of Cretostimogene Grenadenorepvec in Patients With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Bacillus-Calmette-Guerin (BCG)",
"has_exemption": false,
"start_date": "2020-10-27",
"completion_date": "2027-12-24",
"has_results": false,
"results_due": false,
"sponsor_name": "CG Oncology, Inc.",
"sponsor_slug": "cg-oncology-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05378763",
"publication_url": "https://clinicaltrials.gov/study/NCT05378763",
"title": "A Randomized, Phase 3 Study of Poziotinib in Previously Treated Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) Harboring HER2 Exon 20 Mutations (PINNACLE)",
"has_exemption": false,
"start_date": "2022-05-12",
"completion_date": "2027-12-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Spectrum Pharmaceuticals, Inc",
"sponsor_slug": "spectrum-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06025578",
"publication_url": "https://clinicaltrials.gov/study/NCT06025578",
"title": "A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Progressive Pulmonary Fibrosis",
"has_exemption": false,
"start_date": "2023-10-25",
"completion_date": "2027-12-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06385080",
"publication_url": "https://clinicaltrials.gov/study/NCT06385080",
"title": "A Phase 1b/2, Open-label Study of Amivantamab Monotherapy and Amivantamab in Addition to Other Therapeutic Agents in Participants With Head and Neck Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2024-04-22",
"completion_date": "2027-12-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05879250",
"publication_url": "https://clinicaltrials.gov/study/NCT05879250",
"title": "A Multi-Arm, Open Label, Phase II Trial of WP1066 and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma",
"has_exemption": false,
"start_date": "2024-05-22",
"completion_date": "2027-12-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07219420",
"publication_url": "https://clinicaltrials.gov/study/NCT07219420",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study With Open-Label Extension to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Palmoplantar Pustulosis",
"has_exemption": false,
"start_date": "2025-11-14",
"completion_date": "2027-12-27",
"has_results": false,
"results_due": false,
"sponsor_name": "UCB Biopharma SRL",
"sponsor_slug": "ucb-biopharma-srl",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07223203",
"publication_url": "https://clinicaltrials.gov/study/NCT07223203",
"title": "TRITON-PN: A Phase 3, Global, Randomized, Open-Label Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin-Mediated Amyloidosis With Polyneuropathy (hATTR-PN)",
"has_exemption": false,
"start_date": "2025-12-31",
"completion_date": "2027-12-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Alnylam Pharmaceuticals",
"sponsor_slug": "alnylam-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06722235",
"publication_url": "https://clinicaltrials.gov/study/NCT06722235",
"title": "A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate Efficacy and Safety of Mezagitamab Subcutaneous Injection in Participants With Chronic Primary Immune Thrombocytopenia",
"has_exemption": false,
"start_date": "2025-02-27",
"completion_date": "2027-12-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT01174108",
"publication_url": "https://clinicaltrials.gov/study/NCT01174108",
"title": "Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-Cells",
"has_exemption": false,
"start_date": "2010-12-10",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Heart, Lung, and Blood Institute (NHLBI)",
"sponsor_slug": "national-heart-lung-and-blood-institute-nhlbi",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT04855825",
"publication_url": "https://clinicaltrials.gov/study/NCT04855825",
"title": "Investigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS",
"has_exemption": false,
"start_date": "2017-10-05",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Kessler Foundation",
"sponsor_slug": "kessler-foundation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03650114",
"publication_url": "https://clinicaltrials.gov/study/NCT03650114",
"title": "An Open-label, Single Arm, Multi-center Extension Study Evaluating Long-term Safety, Tolerability and Effectiveness of Ofatumumab in Subjects With Relapsing Multiple Sclerosis",
"has_exemption": false,
"start_date": "2018-12-28",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04061148",
"publication_url": "https://clinicaltrials.gov/study/NCT04061148",
"title": "Clinical Testing of Near Infrared Spectroscopy (NIRS) for Quantitative Assessment of Depression",
"has_exemption": false,
"start_date": "2019-01-04",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03919435",
"publication_url": "https://clinicaltrials.gov/study/NCT03919435",
"title": "Trimethoprim-Sulfamethoxazole Effects on the Nasal Microbiome in Granulomatosis With Polyangiitis",
"has_exemption": false,
"start_date": "2019-03-27",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04017650",
"publication_url": "https://clinicaltrials.gov/study/NCT04017650",
"title": "Phase I/II Trial of Encorafenib, Cetuximab, and Nivolumab in Microsatellite Stable BRAFV600E Metastatic Colorectal Cancer (BMS-MDACC CA209-8P6/ARRAY IST-818-101X)",
"has_exemption": false,
"start_date": "2019-06-14",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04183166",
"publication_url": "https://clinicaltrials.gov/study/NCT04183166",
"title": "A Randomized Phase I/II Trial in Patients With Newly Diagnosed, Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN) Evaluating a Mutanome-directed Immunotherapy.",
"has_exemption": false,
"start_date": "2019-12-12",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Transgene",
"sponsor_slug": "transgene",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05358704",
"publication_url": "https://clinicaltrials.gov/study/NCT05358704",
"title": "Preoperative ChemoRadiation And FOLFOXIRI To Escalate Complete Response for Rectal Cancer (CRAFTER)",
"has_exemption": false,
"start_date": "2022-05-13",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Rutgers, The State University of New Jersey",
"sponsor_slug": "rutgers-the-state-university-of-new-jersey",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05712694",
"publication_url": "https://clinicaltrials.gov/study/NCT05712694",
"title": "ADI-PEG 20 or Placebo Plus Gemcitabine and Docetaxel in Previously Treated Subjects With Leiomyosarcoma (ARGSARC): A Randomized, Double Blind, Multi-Center Phase 3 Trial",
"has_exemption": false,
"start_date": "2023-11-29",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Polaris Group",
"sponsor_slug": "polaris-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06180733",
"publication_url": "https://clinicaltrials.gov/study/NCT06180733",
"title": "Neo-adjuvant Pembrolizumab as an Alternative Treatment for MMRd Uterine Cancer, a Phase II Efficacy Study",
"has_exemption": false,
"start_date": "2023-12-01",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University Medical Center Groningen",
"sponsor_slug": "university-medical-center-groningen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06120803",
"publication_url": "https://clinicaltrials.gov/study/NCT06120803",
"title": "Effect of Esomeprazole on Radiation Induced Esophagitis in Non-small Cell Lung Cancer (EERENs): A Phase II Single Arm Study",
"has_exemption": false,
"start_date": "2024-03-01",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Rush University Medical Center",
"sponsor_slug": "rush-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05110742",
"publication_url": "https://clinicaltrials.gov/study/NCT05110742",
"title": "Phase I/II Study of CD5 CAR Engineered IL15-Transduced Cord Blood-Derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Hematological Malignances",
"has_exemption": false,
"start_date": "2024-04-22",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06740955",
"publication_url": "https://clinicaltrials.gov/study/NCT06740955",
"title": "A Randomized, Open, Controlled, Multi-center Clinical Trial of Hypofractionated Postoperative Radiotherapy for Adult Glioblastoma",
"has_exemption": false,
"start_date": "2024-08-13",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "The First Hospital of Jilin University",
"sponsor_slug": "the-first-hospital-of-jilin-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04080778",
"publication_url": "https://clinicaltrials.gov/study/NCT04080778",
"title": "Magnetic Seizure Therapy in Bipolar Depression (MST-BpD) and Treatment Resistant Depression (MST-TRD)",
"has_exemption": false,
"start_date": "2024-08-24",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Joao L. DeQuevedo",
"sponsor_slug": "joao-l-dequevedo",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06868615",
"publication_url": "https://clinicaltrials.gov/study/NCT06868615",
"title": "AVAVA MIRIA General Use",
"has_exemption": false,
"start_date": "2024-09-11",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AVAVA, Inc.",
"sponsor_slug": "avava-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06735755",
"publication_url": "https://clinicaltrials.gov/study/NCT06735755",
"title": "A Phase 1/2, Dose-Exploration Study to Evaluate the Safety and Efficacy of BEAM-301 in Patients With Glycogen Storage Disease Type Ia (GSDIa) Homozygous or Compound Heterozygous for the G6PC1 c.247C>T (p.R83C) Variant",
"has_exemption": false,
"start_date": "2024-12-06",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Beam Therapeutics Inc.",
"sponsor_slug": "beam-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06615479",
"publication_url": "https://clinicaltrials.gov/study/NCT06615479",
"title": "A Phase 3, Randomized, Open-Label, Multicenter Study to Compare the Efficacy and Safety of Arlocabtagene Autoleucel (BMS-986393), a GPRC5D-directed CAR-T Cell Therapy, Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma",
"has_exemption": false,
"start_date": "2025-03-12",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Juno Therapeutics, Inc., a Bristol-Myers Squibb Company",
"sponsor_slug": "juno-therapeutics-inc-a-bristol-myers-squibb-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06690177",
"publication_url": "https://clinicaltrials.gov/study/NCT06690177",
"title": "A Multicenter, Prospective, Randomized, Placebo and Collagenase (Non-surgical Standard-of-care) Controlled Study, Performed to Evaluate the Safety and the Efficacy of EscharEx Drug Product (EX-03 Formulation) and Its Placebo Compared to Collagenase in Patients With Venous Leg Ulcers",
"has_exemption": false,
"start_date": "2025-04-30",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "MediWound Ltd",
"sponsor_slug": "mediwound-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06608277",
"publication_url": "https://clinicaltrials.gov/study/NCT06608277",
"title": "Multi-Center, Randomized, Double-Blind, Placebo-Controlled Trial Comparing Ketamine, Stellate Ganglion Blocks and Combination Treatment to Sham Therapies for Traumatic Brain Injury-Associated Headaches and Post-Traumatic Stress Disorder",
"has_exemption": false,
"start_date": "2025-07-02",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07008638",
"publication_url": "https://clinicaltrials.gov/study/NCT07008638",
"title": "HM2024-29: Phase I/II Clinical Trial of Proteasome Inhibitor in Combination With CPX-351 for the Treatment of Newly-Diagnosed TP53-mutated Acute Myeloid Leukemia (AML)",
"has_exemption": false,
"start_date": "2025-07-07",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Masonic Cancer Center, University of Minnesota",
"sponsor_slug": "masonic-cancer-center-university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06930716",
"publication_url": "https://clinicaltrials.gov/study/NCT06930716",
"title": "Use of Paired Vagus Nerve Stimulation in Mobilization of Patients With Prolonged Disorders of Consciousness: A Pilot Feasibility Study",
"has_exemption": false,
"start_date": "2025-08-12",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Icahn School of Medicine at Mount Sinai",
"sponsor_slug": "icahn-school-of-medicine-at-mount-sinai",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07094711",
"publication_url": "https://clinicaltrials.gov/study/NCT07094711",
"title": "Safety, Immunogenicity, and Efficacy of Therapeutic Mycobacterium Bovis BCG in Patients With Mycobacterium Avium Complex Lung Disease (BOOST)",
"has_exemption": false,
"start_date": "2025-09-30",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Virginia",
"sponsor_slug": "university-of-virginia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06958796",
"publication_url": "https://clinicaltrials.gov/study/NCT06958796",
"title": "Exploratory Use of CMV Immunoglobulin in High Risk (D+R-) Transplant Recipients at the End of Antiviral Prophylaxis to Decrease the Risk of Late CMV Infection",
"has_exemption": false,
"start_date": "2025-11-15",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Camille N. Kotton, MD",
"sponsor_slug": "camille-n-kotton-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06486181",
"publication_url": "https://clinicaltrials.gov/study/NCT06486181",
"title": "A Randomized Controlled Trial for Second Line Treatment of Acute DVT With Endovascular Interventional Treatments",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Rush University Medical Center",
"sponsor_slug": "rush-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05275374",
"publication_url": "https://clinicaltrials.gov/study/NCT05275374",
"title": "A Dose-escalation and Expansion Phase I/IIa Study of XP-102 and XP-102 in Combination With Trametinib in Advanced Solid Tumor Patients With a BRAF V600 Mutation (ENHANCE)",
"has_exemption": false,
"start_date": "2025-12-31",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Xynomic Pharmaceuticals, Inc.",
"sponsor_slug": "xynomic-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07221877",
"publication_url": "https://clinicaltrials.gov/study/NCT07221877",
"title": "A 12-month Open-label, Phase 4 Multicenter Safety Study to Evaluate the Effect of KarXT on Voiding Dynamics and Urological Safety",
"has_exemption": false,
"start_date": "2026-01-21",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07215403",
"publication_url": "https://clinicaltrials.gov/study/NCT07215403",
"title": "Open-Label, Multi-Stage Study to Optimize the Intraputaminal Administration of AB-1005 Using a Prescriptive Infusion Algorithm (PIA)",
"has_exemption": false,
"start_date": "2026-05-01",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AskBio Inc",
"sponsor_slug": "askbio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07205796",
"publication_url": "https://clinicaltrials.gov/study/NCT07205796",
"title": "A Phase 2, Randomized, Multicenter, Active-controlled, Double-blind Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of a 2-dose Regimen of Herpes Zoster IN001 mRNA Vaccine (IN001) in Healthy Participants 50 to 79 Years Old",
"has_exemption": false,
"start_date": "2026-05-01",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Shenzhen Shenxin Biotechnology Co., Ltd",
"sponsor_slug": "shenzhen-shenxin-biotechnology-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05217498",
"publication_url": "https://clinicaltrials.gov/study/NCT05217498",
"title": "A Selective Adenosine 2a Antagonist to Enhance Training-related Gains in Walking Function for Persons With Chronic, Incomplete Spinal Cord Injury",
"has_exemption": false,
"start_date": "2027-09-01",
"completion_date": "2027-12-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Randy Trumbower, PT, PhD",
"sponsor_slug": "randy-trumbower-pt-phd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT01230866",
"publication_url": "https://clinicaltrials.gov/study/NCT01230866",
"title": "A Phase III Prospective Randomized Trial of Standard-fractionation vs. Hypo-fractionation With Proton Radiation Therapy for Low Risk Adenocarcinoma of the Prostate",
"has_exemption": false,
"start_date": "2010-11-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Proton Collaborative Group",
"sponsor_slug": "proton-collaborative-group",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT00977977",
"publication_url": "https://clinicaltrials.gov/study/NCT00977977",
"title": "Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy",
"has_exemption": false,
"start_date": "2010-12-22",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
"sponsor_slug": "national-institute-of-diabetes-and-digestive-and-kidney-diseases-niddk",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02138669",
"publication_url": "https://clinicaltrials.gov/study/NCT02138669",
"title": "INTACS® Prescription Inserts Used to Treat Patients With Keratoconus as a Humanitarian Use Device",
"has_exemption": false,
"start_date": "2011-01-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT01508390",
"publication_url": "https://clinicaltrials.gov/study/NCT01508390",
"title": "Phase II Study of Hypofractionated Stereotactic Body Radiation Therapy as a Boost to the Prostate for Treatment of Localized, Non-Metastatic, High Risk Prostate Cancer",
"has_exemption": false,
"start_date": "2011-06-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Medical Center",
"sponsor_slug": "boston-medical-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT01861106",
"publication_url": "https://clinicaltrials.gov/study/NCT01861106",
"title": "Allogeneic Hematopoietic Stem Cell Transplant for Patients With Mutations in GATA2 or the MonoMAC Syndrome",
"has_exemption": false,
"start_date": "2013-07-24",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02310867",
"publication_url": "https://clinicaltrials.gov/study/NCT02310867",
"title": "Immunomodulation to Optimize Vascularized Composite Allograft Integration for Limb Loss Therapy",
"has_exemption": false,
"start_date": "2015-03-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Linda Cendales",
"sponsor_slug": "linda-cendales",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02755896",
"publication_url": "https://clinicaltrials.gov/study/NCT02755896",
"title": "Prone Partial Breast Irradiation (PBI): Prospective Randomized Controlled Non-inferiority Trial to Compare Radiation Fibrosis With Five Versus Three Fractions",
"has_exemption": false,
"start_date": "2015-07-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02724228",
"publication_url": "https://clinicaltrials.gov/study/NCT02724228",
"title": "A Phase 2, Open-Label, Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of BMN 111 in Children With Achondroplasia",
"has_exemption": false,
"start_date": "2016-01-26",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "BioMarin Pharmaceutical",
"sponsor_slug": "biomarin-pharmaceutical",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02641145",
"publication_url": "https://clinicaltrials.gov/study/NCT02641145",
"title": "Molecular Imaging of Primary Amyloid Cardiomyopathy",
"has_exemption": false,
"start_date": "2016-04-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02945631",
"publication_url": "https://clinicaltrials.gov/study/NCT02945631",
"title": "Quarterback 22: A Phase II Clinical Trial of Sequential Therapy and De-Intensified Chemoradiotherapy for Locally Advanced HPV Positive Oropharynx Cancer",
"has_exemption": false,
"start_date": "2016-04-25",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Icahn School of Medicine at Mount Sinai",
"sponsor_slug": "icahn-school-of-medicine-at-mount-sinai",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02781883",
"publication_url": "https://clinicaltrials.gov/study/NCT02781883",
"title": "A Phase IIa, Open-label, Clinical Trial to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of BP1001 (a Liposomal Grb2 Antisense Oligonucleotide) in Combination With Venetoclax Plus Decitabine in Patients With AML Who Are Ineligible for Intensive Induction Therapy",
"has_exemption": false,
"start_date": "2016-05-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Bio-Path Holdings, Inc.",
"sponsor_slug": "bio-path-holdings-inc",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03073785",
"publication_url": "https://clinicaltrials.gov/study/NCT03073785",
"title": "A Randomized Phase II Study of the Efficacy and Safety of Hypofractionated Stereotactic Radiotherapy and 5FU or Capecitabine With and Without Zometa in Patients With Locally Advanced Pancreatic Adenocarcinoma",
"has_exemption": false,
"start_date": "2016-09-16",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Nebraska",
"sponsor_slug": "university-of-nebraska",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02734537",
"publication_url": "https://clinicaltrials.gov/study/NCT02734537",
"title": "Phase II Randomized Trial of Radiotherapy With or Without Cisplatin for Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN) With TP53 Sequencing",
"has_exemption": false,
"start_date": "2016-11-23",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ECOG-ACRIN Cancer Research Group",
"sponsor_slug": "ecog-acrin-cancer-research-group",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02696993",
"publication_url": "https://clinicaltrials.gov/study/NCT02696993",
"title": "Phase I/II Trial of Nivolumab With Radiation or Nivolumab and Ipilimumab With Radiation for the Treatment of Intracranial Metastases From Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2016-12-16",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03147885",
"publication_url": "https://clinicaltrials.gov/study/NCT03147885",
"title": "A Phase 1b/2 Investigator Initiated Study of RCHOP in Combination With Selinexor (KPT-330) in B Cell Non-Hodgkin's Lymphoma",
"has_exemption": false,
"start_date": "2017-06-20",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Barbara Ann Karmanos Cancer Institute",
"sponsor_slug": "barbara-ann-karmanos-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03244020",
"publication_url": "https://clinicaltrials.gov/study/NCT03244020",
"title": "Low Molecular Weight Heparin Versus Aspirin for Venous Thromboembolism Prophylaxis in Orthopaedic Oncology",
"has_exemption": false,
"start_date": "2018-02-16",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03377517",
"publication_url": "https://clinicaltrials.gov/study/NCT03377517",
"title": "A Pilot Study of Stereotactic Radiosurgical Hypophysectomy for Intractable Pain From Bone Metastases",
"has_exemption": false,
"start_date": "2018-05-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
"sponsor_slug": "sidney-kimmel-comprehensive-cancer-center-at-johns-hopkins",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03150511",
"publication_url": "https://clinicaltrials.gov/study/NCT03150511",
"title": "Tesamorelin Therapy to Enhance Axonal Regeneration, Minimize Muscle Atrophy, and Improve Functional Outcomes Following Peripheral Nerve Injury",
"has_exemption": false,
"start_date": "2018-06-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03233711",
"publication_url": "https://clinicaltrials.gov/study/NCT03233711",
"title": "A Randomized Phase III Study of Nivolumab After Combined Modality Therapy (CMT) in High Risk Anal Cancer",
"has_exemption": false,
"start_date": "2018-07-05",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03600441",
"publication_url": "https://clinicaltrials.gov/study/NCT03600441",
"title": "Open-label, Single-Arm, Phase 2 Study of Oral HDAC-inhibitor Abexinostat in Patients With Relapsed or Refractory Follicular Lymphoma (FORERUNNER)",
"has_exemption": false,
"start_date": "2018-08-27",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Xynomic Pharmaceuticals, Inc.",
"sponsor_slug": "xynomic-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03589729",
"publication_url": "https://clinicaltrials.gov/study/NCT03589729",
"title": "Cardioprotection With Dexrazoxane in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS), Myeloid Blast Phase of Chronic Myeloid Leukemia (CML), Ph+ AML, and Myeloid Blast Phase of Myeloproliferative Neoplasms",
"has_exemption": false,
"start_date": "2018-09-19",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT00583817",
"publication_url": "https://clinicaltrials.gov/study/NCT00583817",
"title": "Endovascular Treatment of Thoracic Aortic Disease",
"has_exemption": false,
"start_date": "2018-10-25",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Matthew Eagleton",
"sponsor_slug": "matthew-eagleton",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04561791",
"publication_url": "https://clinicaltrials.gov/study/NCT04561791",
"title": "Evaluation of Tethered Capsule Endomicroscopy as a Screening Tool for Barrett's Esophagus in the Primary Care Setting",
"has_exemption": false,
"start_date": "2019-01-02",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04541693",
"publication_url": "https://clinicaltrials.gov/study/NCT04541693",
"title": "Early Stability Assessment of the REDAPT Revision Hip System With Radiostereometric Analysis",
"has_exemption": false,
"start_date": "2019-01-15",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Orthopaedic Innovation Centre",
"sponsor_slug": "orthopaedic-innovation-centre",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03731000",
"publication_url": "https://clinicaltrials.gov/study/NCT03731000",
"title": "Study of PHIL® Embolic System in the Treatment of Intracranial Dural Arteriovenous Fistulas in the Pediatric Population",
"has_exemption": false,
"start_date": "2019-04-16",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Alejandro Berenstein",
"sponsor_slug": "alejandro-berenstein",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04876638",
"publication_url": "https://clinicaltrials.gov/study/NCT04876638",
"title": "Minocycline as a Neuroprotective Agent Against Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage",
"has_exemption": false,
"start_date": "2019-07-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Southern California",
"sponsor_slug": "university-of-southern-california",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03869905",
"publication_url": "https://clinicaltrials.gov/study/NCT03869905",
"title": "Aquamin®, a Multi-mineral Natural Product From Red Marine Algae, as an Adjuvant Intervention for Mild Ulcerative Colitis and Ulcerative Colitis in Remission",
"has_exemption": false,
"start_date": "2019-08-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "James Varani",
"sponsor_slug": "james-varani",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03933384",
"publication_url": "https://clinicaltrials.gov/study/NCT03933384",
"title": "Tenofovir Alafenamide Versus Entecavir for the Treatment of Chronic Hepatitis B: an Open Label, Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2019-08-19",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Taichung Veterans General Hospital",
"sponsor_slug": "taichung-veterans-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03643861",
"publication_url": "https://clinicaltrials.gov/study/NCT03643861",
"title": "RAD 1802: A Pilot Trial of Five Fraction Stereotactic Body Radiotherapy for Early Stage Breast Cancer Patients Eligible for Post-Operative Accelerated Partial Breast Irradiation (APBI)",
"has_exemption": false,
"start_date": "2019-08-20",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03779854",
"publication_url": "https://clinicaltrials.gov/study/NCT03779854",
"title": "Multi-Center Phase II Randomized Controlled Trial of Naïve T Cell Depletion for Prevention of Chronic Graft-Versus-Host Disease in Children and Young Adults",
"has_exemption": false,
"start_date": "2019-08-29",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04093570",
"publication_url": "https://clinicaltrials.gov/study/NCT04093570",
"title": "An Open-Label, Multicenter, Extension Study for Subjects Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)",
"has_exemption": false,
"start_date": "2019-09-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Taiho Oncology, Inc.",
"sponsor_slug": "taiho-oncology-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04165330",
"publication_url": "https://clinicaltrials.gov/study/NCT04165330",
"title": "A Phase 1/2a Evaluation of the Safety and Efficacy of Adding AL3818 (Catequentinib) to Nivolumab in Solid Tumors",
"has_exemption": false,
"start_date": "2019-10-17",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sarcoma Oncology Research Center, LLC",
"sponsor_slug": "sarcoma-oncology-research-center-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04058561",
"publication_url": "https://clinicaltrials.gov/study/NCT04058561",
"title": "Hospital-Based Cluster Stratified Randomization Control Trial: Determination of Best Magnetically Controlled Growing Rods Implementation Strategy Using Distraction Intervals",
"has_exemption": false,
"start_date": "2019-11-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Pediatric Spine Foundation",
"sponsor_slug": "pediatric-spine-foundation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04097145",
"publication_url": "https://clinicaltrials.gov/study/NCT04097145",
"title": "A Prospective, Multicenter, Randomized, Controlled Pivotal Trial to Evaluate the Safety and Effectiveness of Transcatheter Tricuspid Valve Repair With the Edwards PASCAL Transcatheter Valve Repair System and Optimal Medical Therapy (OMT) Compared to OMT Alone in Patients With Tricuspid Regurgitation",
"has_exemption": false,
"start_date": "2019-12-11",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Edwards Lifesciences",
"sponsor_slug": "edwards-lifesciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04662970",
"publication_url": "https://clinicaltrials.gov/study/NCT04662970",
"title": "Optimization of Cardiac Resynchronization Therapy by Non-Invasive Imaging of Cardiac Electrophysiology: A Pilot Study",
"has_exemption": false,
"start_date": "2020-01-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University Innsbruck",
"sponsor_slug": "medical-university-innsbruck",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04232085",
"publication_url": "https://clinicaltrials.gov/study/NCT04232085",
"title": "Regenerative Medicine to Restore Hematopoiesis and Immune Function in Immunodeficiencies and Inherited Bone Marrow Failures",
"has_exemption": false,
"start_date": "2020-02-12",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
"sponsor_slug": "sidney-kimmel-comprehensive-cancer-center-at-johns-hopkins",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02989948",
"publication_url": "https://clinicaltrials.gov/study/NCT02989948",
"title": "Safety and Effectiveness of Physician-Modified Fenestrated and Branched Aortic Endografting for the Treatment of Thoracoabdominal Aortic Aneurysms (TAAA)",
"has_exemption": false,
"start_date": "2020-04-22",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04402151",
"publication_url": "https://clinicaltrials.gov/study/NCT04402151",
"title": "Single-Arm Phase II Study of PSMA PET/MR Guided Stereotactic Body Radiation Therapy With Simultaneous Integrated Boost (SBRT-SIB) for High-Intermediate and High Risk Prostate Cancer",
"has_exemption": false,
"start_date": "2020-06-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04198870",
"publication_url": "https://clinicaltrials.gov/study/NCT04198870",
"title": "Percutaneous MitraClip Device or Surgical Mitral Valve REpair in PAtients With PrImaRy MItral Regurgitation Who Are Candidates for Surgery (REPAIR MR)",
"has_exemption": false,
"start_date": "2020-07-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Abbott Medical Devices",
"sponsor_slug": "abbott-medical-devices",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04493138",
"publication_url": "https://clinicaltrials.gov/study/NCT04493138",
"title": "Phase I/II Study of Azacitidine in Combination With Quizartinib for Patients With Myelodysplastic Syndromes and Myelodysplastic/Myeloproliferative Neoplasms With FLT3 or CBL Mutations",
"has_exemption": false,
"start_date": "2020-07-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04090567",
"publication_url": "https://clinicaltrials.gov/study/NCT04090567",
"title": "Overcoming PARP Inhibitor Resistance in BRCA Germline Mutation Positive Advanced Breast Cancer",
"has_exemption": false,
"start_date": "2020-07-28",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04480567",
"publication_url": "https://clinicaltrials.gov/study/NCT04480567",
"title": "A Phase 1/2 Open-Label, Dose Escalation Study to Determine the Safety and Efficacy of BMN 307, an Adeno-Associated Virus Vector-Mediated Gene Transfer of Human Phenylalanine Hydroxylase in Subjects with Phenylketonuria",
"has_exemption": false,
"start_date": "2020-09-24",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "BioMarin Pharmaceutical",
"sponsor_slug": "biomarin-pharmaceutical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04554940",
"publication_url": "https://clinicaltrials.gov/study/NCT04554940",
"title": "A Randomized, Controlled, Open-label Clinical Trial With an Open-label Extension to Investigate the Safety of Vosoritide in Infants and Young Children With Achondroplasia at Risk of Requiring Cervicomedullary Decompression Surgery",
"has_exemption": false,
"start_date": "2020-10-10",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "BioMarin Pharmaceutical",
"sponsor_slug": "biomarin-pharmaceutical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04394546",
"publication_url": "https://clinicaltrials.gov/study/NCT04394546",
"title": "WATCHMAN FLX Versus NOAC for Embolic ProtectION in in the Management of Patients With Non-Valvular Atrial Fibrillation",
"has_exemption": false,
"start_date": "2020-10-15",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Scientific Corporation",
"sponsor_slug": "boston-scientific-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04222062",
"publication_url": "https://clinicaltrials.gov/study/NCT04222062",
"title": "A Randomized Trial Evaluating GLIADEL Compared to Stereotactic Radiosurgery in Subjects With Metastatic Brain Disease",
"has_exemption": false,
"start_date": "2020-11-06",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Nebraska",
"sponsor_slug": "university-of-nebraska",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04624256",
"publication_url": "https://clinicaltrials.gov/study/NCT04624256",
"title": "Germline DNA-Based Radiosensitivity Biomarker Influence on Toxicity Following Prostate Radiotherapy",
"has_exemption": false,
"start_date": "2020-11-10",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonsson Comprehensive Cancer Center",
"sponsor_slug": "jonsson-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04434807",
"publication_url": "https://clinicaltrials.gov/study/NCT04434807",
"title": "Ultra-Early, Minimally inVAsive intraCerebral Haemorrhage evacUATion Versus Standard trEatment (EVACUATE)",
"has_exemption": false,
"start_date": "2020-11-15",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Melbourne",
"sponsor_slug": "university-of-melbourne",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03127267",
"publication_url": "https://clinicaltrials.gov/study/NCT03127267",
"title": "Phase 3 Study to Compare the Efficacy and Safety of Masitinib in Combination With Riluzole Versus Placebo in Combination With Riluzole in the Treatment of Patients Suffering From Amyotrophic Lateral Sclerosis (ALS)",
"has_exemption": false,
"start_date": "2021-02-02",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AB Science",
"sponsor_slug": "ab-science",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04567420",
"publication_url": "https://clinicaltrials.gov/study/NCT04567420",
"title": "A Randomized, Phase II Trial of Circulating Tumor DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE)",
"has_exemption": false,
"start_date": "2021-02-09",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Criterium, Inc.",
"sponsor_slug": "criterium-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04392037",
"publication_url": "https://clinicaltrials.gov/study/NCT04392037",
"title": "A Phase 2 Study of CC220 (Iberdomide) Combined With Low-dose Cyclophosphamide and Dexamethasone in Relapsed/Refractory Multiple Myeloma (IberCd): ICON Study",
"has_exemption": false,
"start_date": "2021-02-17",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Amsterdam UMC, location VUmc",
"sponsor_slug": "amsterdam-umc-location-vumc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04566328",
"publication_url": "https://clinicaltrials.gov/study/NCT04566328",
"title": "Effective Quadruplet Utilization After Treatment Evaluation (EQUATE): A Randomized Phase 3 Trial for Newly Diagnosed Multiple Myeloma Not Intended for Early Autologous Transplantation",
"has_exemption": false,
"start_date": "2021-02-24",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ECOG-ACRIN Cancer Research Group",
"sponsor_slug": "ecog-acrin-cancer-research-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04804007",
"publication_url": "https://clinicaltrials.gov/study/NCT04804007",
"title": "Randomized Phase 2 Trial of Maintenance Oral Etoposide or Observation Following High-dose Chemotherapy for Relapsed Metastatic Germ-Cell Tumor",
"has_exemption": false,
"start_date": "2021-03-03",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Nabil Adra",
"sponsor_slug": "nabil-adra",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04616560",
"publication_url": "https://clinicaltrials.gov/study/NCT04616560",
"title": "A Phase 2 Study of DS-8201a (NSC# 807708) in Adolescents, or Young Adults With Recurrent HER2+ Osteosarcoma",
"has_exemption": false,
"start_date": "2021-03-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04729933",
"publication_url": "https://clinicaltrials.gov/study/NCT04729933",
"title": "Implantation of a Permanent Interatrial Shunt to Reduce Left Atrial Filling Pressures Following MitraClip: The V-Wave Shunt MitraClip Study",
"has_exemption": false,
"start_date": "2021-03-11",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Samir Kapadia",
"sponsor_slug": "samir-kapadia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04225611",
"publication_url": "https://clinicaltrials.gov/study/NCT04225611",
"title": "Randomized, Prospective, Vehicle-Controlled, Phase I/II Clinical Trial to Evaluate the Safety and Feasibility of a Therapeutic Contact Lens Drug Delivery System (TCL-DDS) in Patients With Recurrent Cystoid Macular Edema",
"has_exemption": false,
"start_date": "2021-03-15",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts Eye and Ear Infirmary",
"sponsor_slug": "massachusetts-eye-and-ear-infirmary",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04816604",
"publication_url": "https://clinicaltrials.gov/study/NCT04816604",
"title": "An Open-label Extension Study Evaluating the Long-term Safety and Efficacy of Oral Inhalation of GB002 for the Treatment of WHO Group 1 Pulmonary Arterial Hypertension (PAH)",
"has_exemption": false,
"start_date": "2021-04-05",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "GB002, Inc., a wholly owned subsidiary of Gossamer Bio, Inc.",
"sponsor_slug": "gb002-inc-a-wholly-owned-subsidiary-of-gossamer-bio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04647916",
"publication_url": "https://clinicaltrials.gov/study/NCT04647916",
"title": "A Phase II Trial of Sacituzumab Govitecan (IMMU-132) (NSC #820016) for Patients With HER2-Negative Breast Cancer and Brain Metastases",
"has_exemption": false,
"start_date": "2021-06-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "SWOG Cancer Research Network",
"sponsor_slug": "swog-cancer-research-network",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05005975",
"publication_url": "https://clinicaltrials.gov/study/NCT05005975",
"title": "A Phase 3, Multicenter, Open-label, Long-term, Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)",
"has_exemption": false,
"start_date": "2021-08-10",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Tanabe Pharma America, Inc.",
"sponsor_slug": "tanabe-pharma-america-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04594187",
"publication_url": "https://clinicaltrials.gov/study/NCT04594187",
"title": "The Role of Nodal Radiation Therapy in Sentinel Lymph Node Positive Melanoma",
"has_exemption": false,
"start_date": "2021-08-26",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04986657",
"publication_url": "https://clinicaltrials.gov/study/NCT04986657",
"title": "A Prospective Study of Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in AML and MDS",
"has_exemption": false,
"start_date": "2021-09-17",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04883463",
"publication_url": "https://clinicaltrials.gov/study/NCT04883463",
"title": "Neuromodulation to Improve Respiratory Function in Cervical Spinal Cord Injury",
"has_exemption": false,
"start_date": "2021-09-27",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Los Angeles",
"sponsor_slug": "university-of-california-los-angeles",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05009992",
"publication_url": "https://clinicaltrials.gov/study/NCT05009992",
"title": "A Combination Therapy Trial Using an Adaptive Platform Design for Children and Young Adults With Diffuse Midline Gliomas (DMGs) Including Diffuse Intrinsic Pontine Gliomas (DIPGs) at Initial Diagnosis, Post-Radiation Therapy and at Time of Progression",
"has_exemption": false,
"start_date": "2021-10-20",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04708054",
"publication_url": "https://clinicaltrials.gov/study/NCT04708054",
"title": "Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS",
"has_exemption": false,
"start_date": "2021-10-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04523857",
"publication_url": "https://clinicaltrials.gov/study/NCT04523857",
"title": "A Phase II Pilot Trial of ABemacicliB or Abemaciclib and HydroxYchloroquine to Target Minimal Residual Disease in Breast Cancer Patients (\"ABBY\")",
"has_exemption": false,
"start_date": "2021-11-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Abramson Cancer Center at Penn Medicine",
"sponsor_slug": "abramson-cancer-center-at-penn-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04735627",
"publication_url": "https://clinicaltrials.gov/study/NCT04735627",
"title": "Real-Time Levodopa Monitoring for Improved Management of Parkinson Disease",
"has_exemption": false,
"start_date": "2021-12-07",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05118789",
"publication_url": "https://clinicaltrials.gov/study/NCT05118789",
"title": "A Phase 1/2 Study of the Highly Selective ROS1 Inhibitor Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors (ARROS-1)",
"has_exemption": false,
"start_date": "2022-01-04",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Nuvalent Inc.",
"sponsor_slug": "nuvalent-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05253495",
"publication_url": "https://clinicaltrials.gov/study/NCT05253495",
"title": "Reducing the Burden of Oncologic Chemoradiotherapy And Radiation Exposure From Diagnostic Imaging by Utilizing Targeted Immunotherapy in Children, Adolescents and Young Adults With Lymphoma",
"has_exemption": false,
"start_date": "2022-02-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "New York Medical College",
"sponsor_slug": "new-york-medical-college",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04775706",
"publication_url": "https://clinicaltrials.gov/study/NCT04775706",
"title": "A Multicenter, Proof-of-concept, Phase 2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of HM15912 (Sonefpeglutide) in Adult Subjects With Short Bowel Syndrome-associated Intestinal Failure (SBS-IF)",
"has_exemption": false,
"start_date": "2022-03-03",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hanmi Pharmaceutical Company Limited",
"sponsor_slug": "hanmi-pharmaceutical-company-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04864054",
"publication_url": "https://clinicaltrials.gov/study/NCT04864054",
"title": "An Open-Label, Dose Escalation, Multi-Center Phase I/II Clinical Trial of ECT204 T-Cell Therapy in Adults With Advanced Hepatocellular Carcinoma (HCC) (ARYA-3)",
"has_exemption": false,
"start_date": "2022-03-11",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eureka Therapeutics Inc.",
"sponsor_slug": "eureka-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04965454",
"publication_url": "https://clinicaltrials.gov/study/NCT04965454",
"title": "Clinical Trial of Biomarkers for Predicting Immunotherapy Response in Hepatocellular Carcinoma",
"has_exemption": false,
"start_date": "2022-03-28",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Queen's Medical Center",
"sponsor_slug": "queens-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04502758",
"publication_url": "https://clinicaltrials.gov/study/NCT04502758",
"title": "A Randomized Controlled Trial of Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation Associated With Major Depressive Disorder",
"has_exemption": false,
"start_date": "2022-04-04",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05289557",
"publication_url": "https://clinicaltrials.gov/study/NCT05289557",
"title": "A Multicenter Trial of the Efficacy and Safety of Bonjesta® for Nausea and Vomiting of Pregnancy in Pregnant Adolescents",
"has_exemption": false,
"start_date": "2022-05-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Duchesnay Inc.",
"sponsor_slug": "duchesnay-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05018585",
"publication_url": "https://clinicaltrials.gov/study/NCT05018585",
"title": "A Phase III, Randomized, Double-blind, Placebo-controlled, Multicenter Trial to Evaluate the Efficacy and Safety of Diamyd® to Preserve Endogenous Beta Cell Function in Adolescents and Adults With Recently Diagnosed Type 1 Diabetes, Carrying the Genetic HLA DR3-DQ2 Haplotype",
"has_exemption": false,
"start_date": "2022-05-19",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Diamyd Medical AB",
"sponsor_slug": "diamyd-medical-ab",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05312892",
"publication_url": "https://clinicaltrials.gov/study/NCT05312892",
"title": "Sympathetic Mechanisms in the Cardiovascular and Metabolic Alterations of Obesity, Crossover Design Study.",
"has_exemption": false,
"start_date": "2022-05-20",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt University Medical Center",
"sponsor_slug": "vanderbilt-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05384626",
"publication_url": "https://clinicaltrials.gov/study/NCT05384626",
"title": "A Phase 1/2 Study of the Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor NVL-655 in Patients With Advanced NSCLC and Other Solid Tumors (ALKOVE-1)",
"has_exemption": false,
"start_date": "2022-06-09",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Nuvalent Inc.",
"sponsor_slug": "nuvalent-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04981509",
"publication_url": "https://clinicaltrials.gov/study/NCT04981509",
"title": "A Phase 2 Study of Bevacizumab, Erlotinib and Atezolizumab in Subjects With Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) Associated or Sporadic Papillary Renal Cell Cancer",
"has_exemption": false,
"start_date": "2022-06-10",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05371613",
"publication_url": "https://clinicaltrials.gov/study/NCT05371613",
"title": "A Phase 2/3, Multicenter, Double-Blind, Randomized Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase in Pediatric and Young Adult Participants With Neuronopathic or Non-Neuronopathic Mucopolysaccharidosis Type II",
"has_exemption": false,
"start_date": "2022-07-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Denali Therapeutics Inc.",
"sponsor_slug": "denali-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05431270",
"publication_url": "https://clinicaltrials.gov/study/NCT05431270",
"title": "A Phase 1, Open-Label, Dose Escalation and Expansion Study of Mavrostobart (PT199) Administered Alone in Adult Patients with Advanced Solid TuMORs, in CombiNation with a Checkpoint INhibitor TreatinG Wild-type Non-Small Cell Lung Cancer, or in Combination with ChemoTherapy for Metastatic or Advanced PAncreatic Ductal AdenocaRcinoma (MORNINGSTAR)",
"has_exemption": false,
"start_date": "2022-08-11",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Phanes Therapeutics",
"sponsor_slug": "phanes-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04929041",
"publication_url": "https://clinicaltrials.gov/study/NCT04929041",
"title": "A Randomized Phase II/III Trial of Modern Immunotherapy Based Systemic Therapy With or Without Radiation Therapy for PD-L1-Negative, Advanced Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2022-10-07",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05488626",
"publication_url": "https://clinicaltrials.gov/study/NCT05488626",
"title": "Daily Adaptive vs Non-Adaptive External Beam Radiation Therapy With Concurrent Chemotherapy for Locally Advanced Non-Small Cell Lung Cancer: A Prospective Randomized Trial of an Individualized Approach for Toxicity Reduction (ARTIA-Lung)",
"has_exemption": false,
"start_date": "2022-10-20",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Varian, a Siemens Healthineers Company",
"sponsor_slug": "varian-a-siemens-healthineers-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05286814",
"publication_url": "https://clinicaltrials.gov/study/NCT05286814",
"title": "Phase II Study Evaluating the Efficacy of PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma",
"has_exemption": false,
"start_date": "2022-10-24",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05672849",
"publication_url": "https://clinicaltrials.gov/study/NCT05672849",
"title": "Safety and Efficacy of Devices Used in Fetoscopic Neural Tube Defect Repair Cases",
"has_exemption": false,
"start_date": "2022-11-14",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Michael A Belfort",
"sponsor_slug": "michael-a-belfort",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05534971",
"publication_url": "https://clinicaltrials.gov/study/NCT05534971",
"title": "A Randomized Study Comparing Two Techniques for Central Venous Catheter Insertion",
"has_exemption": false,
"start_date": "2022-11-16",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Montefiore Medical Center",
"sponsor_slug": "montefiore-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05091372",
"publication_url": "https://clinicaltrials.gov/study/NCT05091372",
"title": "Minimal Residual Disease Guided Maintenance Therapy With Belantamab Mafodotin and Lenalidomide After Autologous Hematopoietic Cell Transplantation in Patients With Newly Diagnosed Multiple Myeloma",
"has_exemption": false,
"start_date": "2022-12-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06007872",
"publication_url": "https://clinicaltrials.gov/study/NCT06007872",
"title": "Feasibility: Intracardiac Echocardiography Guided Watchman Device Implant",
"has_exemption": false,
"start_date": "2022-12-02",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Cleveland Clinic",
"sponsor_slug": "the-cleveland-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05515536",
"publication_url": "https://clinicaltrials.gov/study/NCT05515536",
"title": "Long-Term Open-Label Study to Assess the Safety and Efficacy of Vatiquinone in Patients With Friedreich Ataxia",
"has_exemption": false,
"start_date": "2022-12-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "PTC Therapeutics",
"sponsor_slug": "ptc-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05660018",
"publication_url": "https://clinicaltrials.gov/study/NCT05660018",
"title": "TMS Related Biomarker Assessments",
"has_exemption": false,
"start_date": "2023-01-07",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Maryland, Baltimore",
"sponsor_slug": "university-of-maryland-baltimore",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05512208",
"publication_url": "https://clinicaltrials.gov/study/NCT05512208",
"title": "A Phase 2 Study of VS-6766 (Dual RAF/MEK Inhibitor) Plus Defactinib (FAK Inhibitor) in Recurrent Gynecological Cancers (DURAFAK)",
"has_exemption": false,
"start_date": "2023-02-06",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Oklahoma",
"sponsor_slug": "university-of-oklahoma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05676931",
"publication_url": "https://clinicaltrials.gov/study/NCT05676931",
"title": "A Phase II, Open-label, Platform Study, to Evaluate Immunotherapy-based Combinations in Participants With Advanced Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2023-02-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Gilead Sciences",
"sponsor_slug": "gilead-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05608252",
"publication_url": "https://clinicaltrials.gov/study/NCT05608252",
"title": "A Single Arm Phase 1/2 Trial of Abemaciclib + VS-6766 + Fulvestrant in Metastatic HR+/HER2- Breast Cancer",
"has_exemption": false,
"start_date": "2023-02-23",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Adrienne G. Waks",
"sponsor_slug": "adrienne-g-waks",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05735483",
"publication_url": "https://clinicaltrials.gov/study/NCT05735483",
"title": "A Phase 3, Multicenter, Long-Term Extension Study to Assess the Safety and Efficacy of Lebrikizumab in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis",
"has_exemption": false,
"start_date": "2023-03-09",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05594563",
"publication_url": "https://clinicaltrials.gov/study/NCT05594563",
"title": "TArgeting Type 1 Diabetes Using POLyamines (TADPOL): A Randomized, Double-Masked, Placebo-Controlled Phase 2 Study to Evaluate the Efficacy and Safety of Difluoromethylornithine (DFMO) to Preserve Insulin Production in Type 1 Diabetes",
"has_exemption": false,
"start_date": "2023-03-14",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Emily K. Sims",
"sponsor_slug": "emily-k-sims",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05482893",
"publication_url": "https://clinicaltrials.gov/study/NCT05482893",
"title": "A Phase 1/2, Open-Label, Dose Escalation and Expansion Study With PT886 (Spevatamig) Followed by a Multi-cohorT Study in Patients With Advanced GastrIc, Gastroesophageal JuNction, Pancreatic Ductal or Biliary Tract AdEnocarcinomas of PT886, in Combination With ChemotherApy, and/or an Immune ChecKpoint Inhibitor. The TWINPEAK Study",
"has_exemption": false,
"start_date": "2023-03-15",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Phanes Therapeutics",
"sponsor_slug": "phanes-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05734313",
"publication_url": "https://clinicaltrials.gov/study/NCT05734313",
"title": "Telemedicine-Delivered Unified Protocol for Cognitive Behavioral Therapy for Anxiety and Depression in Young Adults With Type 1 Diabetes",
"has_exemption": false,
"start_date": "2023-03-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Albert Einstein College of Medicine",
"sponsor_slug": "albert-einstein-college-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05103345",
"publication_url": "https://clinicaltrials.gov/study/NCT05103345",
"title": "A Phase I/IIa, Open-label, Dose Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Modified Salmonella Typhimurium SGN1 Administered Via Intratumoral Injection in Patients With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2023-04-19",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Guangzhou Sinogen Pharmaceutical Co., Ltd",
"sponsor_slug": "guangzhou-sinogen-pharmaceutical-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05019703",
"publication_url": "https://clinicaltrials.gov/study/NCT05019703",
"title": "A Phase 2 Trial of Atezolizumab and Cabozantinib in Adolescents and Young Adults With Recurrent/Metastatic Osteosarcoma (TACOS)",
"has_exemption": false,
"start_date": "2023-04-25",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05551104",
"publication_url": "https://clinicaltrials.gov/study/NCT05551104",
"title": "Safest Choice of Antihypertensive Regimen for Postpartum Hypertension: A Randomized Control Trial (SCARPH)",
"has_exemption": false,
"start_date": "2023-05-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Loma Linda University",
"sponsor_slug": "loma-linda-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05586581",
"publication_url": "https://clinicaltrials.gov/study/NCT05586581",
"title": "PET Imaging of Synaptic Density Combined With Neuroimmunologic Measures to Reveal Mechanisms of HIV Neuropathogenesis During ART",
"has_exemption": false,
"start_date": "2023-05-17",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05726370",
"publication_url": "https://clinicaltrials.gov/study/NCT05726370",
"title": "A Phase 2 Study of Preoperative Pembrolizumab and Chemotherapy Followed by Adjuvant Pembrolizumab in Resectable Locoregionally Recurrent Head and Neck Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2023-05-20",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Dana-Farber Cancer Institute",
"sponsor_slug": "dana-farber-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05816603",
"publication_url": "https://clinicaltrials.gov/study/NCT05816603",
"title": "Home-based Post-stroke Fatigue Treatment Using Transcranial Direct Current Stimulation (tDCS)",
"has_exemption": false,
"start_date": "2023-05-23",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05827523",
"publication_url": "https://clinicaltrials.gov/study/NCT05827523",
"title": "Phase III Randomized Trial of HIPEC in Primary Stage Three & Four Primary Ovarian Cancer After Interval Cytoreductive Surgery (FOCUS, KOV-04)",
"has_exemption": false,
"start_date": "2023-05-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Center, Korea",
"sponsor_slug": "national-cancer-center-korea",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05885022",
"publication_url": "https://clinicaltrials.gov/study/NCT05885022",
"title": "Feasibility Clinical Evaluation of the Calibreye System",
"has_exemption": false,
"start_date": "2023-05-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Myra Vision Inc.",
"sponsor_slug": "myra-vision-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05655312",
"publication_url": "https://clinicaltrials.gov/study/NCT05655312",
"title": "A Phase I/IIa, First-In-Human, Multi-Center, Monotherapy and Combination-Therapy With Nivolumab, Dose-Finding and Dose-Expansion Study of [212Pb]VMT01 Melanocortin-1 Receptor-Targeted, Image-Guided Alpha-Particle Therapy in Subjects With Previously Treated Unresectable or Metastatic Melanoma",
"has_exemption": false,
"start_date": "2023-06-01",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Perspective Therapeutics",
"sponsor_slug": "perspective-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06097845",
"publication_url": "https://clinicaltrials.gov/study/NCT06097845",
"title": "Transcranial Ultrasound Via Sonolucent Cranioplasty",
"has_exemption": false,
"start_date": "2023-06-27",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwell Health",
"sponsor_slug": "northwell-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05645718",
"publication_url": "https://clinicaltrials.gov/study/NCT05645718",
"title": "Phase II Study of Pedi-cRIB: Mini-Hyper-CVD With Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric With B-Cell Lineage Acute Lymphocytic Leukemia",
"has_exemption": false,
"start_date": "2023-07-14",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05501678",
"publication_url": "https://clinicaltrials.gov/study/NCT05501678",
"title": "Randomized Placebo-controlled Crossover Trial of Diphenhydramine for Sleep in Children With Autism",
"has_exemption": false,
"start_date": "2023-08-09",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05776979",
"publication_url": "https://clinicaltrials.gov/study/NCT05776979",
"title": "Post-Transplant Maintenance Therapy With Isatuximab Plus Lenalidomide for High-Risk Multiple Myeloma Patients",
"has_exemption": false,
"start_date": "2023-08-17",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05914116",
"publication_url": "https://clinicaltrials.gov/study/NCT05914116",
"title": "A Phase 1/2a, Multicenter, Open-Label, First in Human Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of DB-1311 in Subjects With Advanced/Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2023-08-17",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "DualityBio Inc.",
"sponsor_slug": "dualitybio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05939076",
"publication_url": "https://clinicaltrials.gov/study/NCT05939076",
"title": "First-line Cryoablation for Early Treatment of Persistent Atrial Fibrillation - a Randomized Study Comparing Early Trigger Isolation Using the Cryoballoon Versus Antiarrhythmic Medication",
"has_exemption": false,
"start_date": "2023-08-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Region Örebro County",
"sponsor_slug": "region-orebro-county",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05999630",
"publication_url": "https://clinicaltrials.gov/study/NCT05999630",
"title": "The Use of Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Who Are Treated With Radioactive Iodine for Thyroid Cancer",
"has_exemption": false,
"start_date": "2023-08-21",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt University Medical Center",
"sponsor_slug": "vanderbilt-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05652686",
"publication_url": "https://clinicaltrials.gov/study/NCT05652686",
"title": "An Open-label, Multicenter, Dose Escalation, and Dose Expansion Phase 1/2 Study With Peluntamig (PT217) Followed by a Key ChemotherapY and/or Checkpoint Inhibitor ComBination in Patients With NeuRoendocrIne Carcinomas That Are Known to be DLL3 expressinG CancErs (SKYBRIDGE)",
"has_exemption": false,
"start_date": "2023-09-05",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Phanes Therapeutics",
"sponsor_slug": "phanes-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06047080",
"publication_url": "https://clinicaltrials.gov/study/NCT06047080",
"title": "A Phase III, Multicenter, Randomized, Open-Label Study Comparing the Efficacy and Safety of Glofitamab (RO7082859) in Combination With Polatuzumab Vedotin Plus Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone (Pola-R-CHP) Versus Pola-R-CHP in Previously Untreated Patients With Large B-Cell Lymphoma",
"has_exemption": false,
"start_date": "2023-09-18",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05288855",
"publication_url": "https://clinicaltrials.gov/study/NCT05288855",
"title": "A Double-Blind, Placebo-Controlled, Dose Escalation Study to Assess the Efficacy, Safety and Pharmacokinetics of Voclosporin in Adolescent and Pediatric Subjects With Lupus Nephritis",
"has_exemption": false,
"start_date": "2023-10-10",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Aurinia Pharmaceuticals Inc.",
"sponsor_slug": "aurinia-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05759728",
"publication_url": "https://clinicaltrials.gov/study/NCT05759728",
"title": "A Phase 1/2a, Multicenter, Open-Label, Dose Escalation and Expansion Study of CNA3103 (LGR5-targeted, Autologous CAR-T Cells) Administered to Adult Subjects With Metastatic Colorectal Cancer",
"has_exemption": false,
"start_date": "2023-10-24",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Carina Biotech Limited",
"sponsor_slug": "carina-biotech-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06725758",
"publication_url": "https://clinicaltrials.gov/study/NCT06725758",
"title": "Two-part, First-in-Human Study on ODM-212 in Subjects with Selected Advanced Solid Tumours",
"has_exemption": false,
"start_date": "2023-10-26",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Orion Corporation, Orion Pharma",
"sponsor_slug": "orion-corporation-orion-pharma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05905224",
"publication_url": "https://clinicaltrials.gov/study/NCT05905224",
"title": "A Randomized Clinical Trial to Assess the Efficacy of Reducing the Aligners' Wear Protocol on the Predictability of Orthodontic Tooth Movement",
"has_exemption": false,
"start_date": "2023-10-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Florida",
"sponsor_slug": "university-of-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06072703",
"publication_url": "https://clinicaltrials.gov/study/NCT06072703",
"title": "A Randomized, Sham-Controlled Clinical Trial Evaluating Individualized Neuromodulation of Cortical Regions Involved in Neurogenic Overactive Bladder in Multiple Sclerosis",
"has_exemption": false,
"start_date": "2023-10-30",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Methodist Hospital Research Institute",
"sponsor_slug": "the-methodist-hospital-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06004115",
"publication_url": "https://clinicaltrials.gov/study/NCT06004115",
"title": "Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression",
"has_exemption": false,
"start_date": "2023-11-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Laureate Institute for Brain Research, Inc.",
"sponsor_slug": "laureate-institute-for-brain-research-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05705219",
"publication_url": "https://clinicaltrials.gov/study/NCT05705219",
"title": "Development of 3D Multi-Parametric Ultrasound (MPUS) as a Decision Support Tool for Patients With Abdominal and Pelvic Tumors Undergoing Therapy",
"has_exemption": false,
"start_date": "2023-12-04",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05988411",
"publication_url": "https://clinicaltrials.gov/study/NCT05988411",
"title": "Ultrasound-Based Renal Sympathetic Denervation As Adjunctive Upstream Therapy During Atrial Fibrillation - Redo Ablation Procedures: a Pilot Study",
"has_exemption": false,
"start_date": "2023-12-07",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vivek Reddy",
"sponsor_slug": "vivek-reddy",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06128629",
"publication_url": "https://clinicaltrials.gov/study/NCT06128629",
"title": "MAGNITUDE: A Phase 3, Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)",
"has_exemption": false,
"start_date": "2023-12-13",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Intellia Therapeutics",
"sponsor_slug": "intellia-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06100705",
"publication_url": "https://clinicaltrials.gov/study/NCT06100705",
"title": "A Single Arm Open-label, Phase II Study of Sipuleucel-T With Bipolar Androgen Therapy in Men With Metastatic Castration-resistant Prostate Cancer",
"has_exemption": false,
"start_date": "2023-12-20",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06072807",
"publication_url": "https://clinicaltrials.gov/study/NCT06072807",
"title": "Brain [18F]-FES PET/CT in the Diagnosis, Treatment Planning and Response Assessment of Brain Metastases in Patients With Estrogen-Receptor Positive Breast Cancer",
"has_exemption": false,
"start_date": "2023-12-27",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05761171",
"publication_url": "https://clinicaltrials.gov/study/NCT05761171",
"title": "A Phase 2 Study of Revumenib (SNDX-5613) in Combination With Chemotherapy for Patients With Relapsed or Refractory KMT2A-Rearranged Infant Leukemia",
"has_exemption": false,
"start_date": "2024-01-08",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05641844",
"publication_url": "https://clinicaltrials.gov/study/NCT05641844",
"title": "A Prospective, Multi-Center, Double Blind, Randomized Controlled Study, Evaluating the Safety and Efficacy of RD2 Ver.02, For the Management of Anal Fistulas",
"has_exemption": false,
"start_date": "2024-01-20",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "RedDress Ltd.",
"sponsor_slug": "reddress-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06311513",
"publication_url": "https://clinicaltrials.gov/study/NCT06311513",
"title": "Multi-Center Pilot Study to Evaluate Concentrated Bone Marrow Aspirate (cBMA) as a Treatment to Modify Post-Traumatic Osteoarthritis (PTOA) Following Revision Anterior Cruciate Ligament Reconstruction (ACLR)",
"has_exemption": false,
"start_date": "2024-01-22",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hospital for Special Surgery, New York",
"sponsor_slug": "hospital-for-special-surgery-new-york",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06229210",
"publication_url": "https://clinicaltrials.gov/study/NCT06229210",
"title": "An Open-label, Multicenter Trial to Assess the Safety and Tolerability of Lumateperone in the Treatment of Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder",
"has_exemption": false,
"start_date": "2024-01-25",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Intra-Cellular Therapies, Inc.",
"sponsor_slug": "intra-cellular-therapies-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05669170",
"publication_url": "https://clinicaltrials.gov/study/NCT05669170",
"title": "Evaluating Safety and Potential Benefit of Methylphenidate as a Symptomatic Treatment for Apathy in Veterans With Parkinson's Disease.",
"has_exemption": false,
"start_date": "2024-01-31",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ralph H. Johnson VA Medical Center",
"sponsor_slug": "ralph-h-johnson-va-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05421676",
"publication_url": "https://clinicaltrials.gov/study/NCT05421676",
"title": "Fetal Endoscopic Tracheal Occlusion (FETO) Trial for Congenital Diaphragmatic Hernia",
"has_exemption": false,
"start_date": "2024-02-12",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Davis",
"sponsor_slug": "university-of-california-davis",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06121297",
"publication_url": "https://clinicaltrials.gov/study/NCT06121297",
"title": "A Phase 1/2, Open-label Study to Evaluate the Safety and Efficacy of Autologous CD19-specific Chimeric Antigen Receptor T Cells (CABA-201) in Subjects With Active Systemic Lupus Erythematosus",
"has_exemption": false,
"start_date": "2024-02-16",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Cabaletta Bio",
"sponsor_slug": "cabaletta-bio",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06394284",
"publication_url": "https://clinicaltrials.gov/study/NCT06394284",
"title": "IISPT2: Examining 3,4-methylenedioxymethamphetamine (MDMA) Effects on Psychological, Relational and Hyperarousal-Related Neural Reactivity Mechanisms in Veterans With PTSD and MI",
"has_exemption": false,
"start_date": "2024-02-18",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Herzog Hospital",
"sponsor_slug": "herzog-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06161025",
"publication_url": "https://clinicaltrials.gov/study/NCT06161025",
"title": "A Phase 2/3, Multicenter, Randomized Study of Raludotatug Deruxtecan (R-DXd), a CDH6-directed Antibody-drug Conjugate, in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer",
"has_exemption": false,
"start_date": "2024-02-27",
"completion_date": "2027-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Daiichi Sankyo",
"sponsor_slug": "daiichi-sankyo",
"status": "ongoing",
"is_pact": false,
"days_late": null
}
]
}