HTTP 200 OK
Allow: GET, POST, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"recordsFiltered": 50704,
"recordsTotal": 50704,
"next": "http://fdaaa.trialstracker.net/api/trials/?format=api&length=300&ordering=-days_late&start=45300",
"previous": "http://fdaaa.trialstracker.net/api/trials/?format=api&length=300&ordering=-days_late&start=44700",
"results": [
{
"registry_id": "NCT06939348",
"publication_url": "https://clinicaltrials.gov/study/NCT06939348",
"title": "Safety and Efficacy of Thalamic Focused Ultrasound Stimulation (tFUS) for Promoting Recovery After Severe Traumatic Brain Injury",
"has_exemption": false,
"start_date": "2025-04-26",
"completion_date": "2028-03-28",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Los Angeles",
"sponsor_slug": "university-of-california-los-angeles",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07136181",
"publication_url": "https://clinicaltrials.gov/study/NCT07136181",
"title": "A Multicenter Phase Ib/II Study to Evaluate the Safety, Efficacy and Pharmacokinetics of NBM-BMX in Patients With Metastatic Uveal Melanoma",
"has_exemption": false,
"start_date": "2025-11-20",
"completion_date": "2028-03-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Novelwise Pharmaceutical Corporation",
"sponsor_slug": "novelwise-pharmaceutical-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07290140",
"publication_url": "https://clinicaltrials.gov/study/NCT07290140",
"title": "A Randomized, Controlled, Blinded, Multi-Center Trial to Assess the Safety and Efficacy of Paclitaxel-Coated Sinus Balloon as an Adjunct to Endoscopic Sinus Surgery in Adult Chronic Rhinosinusitis Subjects",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2028-03-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Airiver Medical, Inc.",
"sponsor_slug": "airiver-medical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07508787",
"publication_url": "https://clinicaltrials.gov/study/NCT07508787",
"title": "Phase 2b, Randomized, Multicenter, Double-Blind, Dose-Finding, Active-Controlled Study of Siplizumab (TCD601) Compared to Rabbit Anti-Thymocyte Globulin in Renal Transplant Recipients Requiring Induction Therapy and Receiving Standard of Care Immunosuppression With Tacrolimus, Mycophenolic Acid and Corticosteroids",
"has_exemption": false,
"start_date": "2026-06-29",
"completion_date": "2028-03-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Nefro Avillion Clinical Development, LLC",
"sponsor_slug": "nefro-avillion-clinical-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07221227",
"publication_url": "https://clinicaltrials.gov/study/NCT07221227",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled, 3-Arm Study to Investigate the Safety and Efficacy of Efimosfermin Alfa in Participants With Biopsy-Confirmed F2- or F3-Stage Metabolic Dysfunction-Associated Steatohepatitis (MASH) (ZENITH-1)",
"has_exemption": false,
"start_date": "2025-10-24",
"completion_date": "2028-03-29",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07298473",
"publication_url": "https://clinicaltrials.gov/study/NCT07298473",
"title": "Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)",
"has_exemption": false,
"start_date": "2026-04-08",
"completion_date": "2028-03-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Medtronic Cardiac Ablation Solutions",
"sponsor_slug": "medtronic-cardiac-ablation-solutions",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03950609",
"publication_url": "https://clinicaltrials.gov/study/NCT03950609",
"title": "A Phase II Study of Lenvatinib in Combination With Everolimus in Patients With Advanced Carcinoid Tumors",
"has_exemption": false,
"start_date": "2019-07-30",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05027633",
"publication_url": "https://clinicaltrials.gov/study/NCT05027633",
"title": "Immunotherapy With Chemotherapy and Chemoradiation for Advanced Squamous Cancer of Nasal Cavity / Paranasal Sinuses (I-NAPA)",
"has_exemption": false,
"start_date": "2021-11-02",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05316155",
"publication_url": "https://clinicaltrials.gov/study/NCT05316155",
"title": "Phase 1/2 Study of Erdafitinib Intravesical Delivery System (TAR-210) in Participants With Non-Muscle-Invasive or Muscle-Invasive Bladder Cancer",
"has_exemption": false,
"start_date": "2022-04-11",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05811364",
"publication_url": "https://clinicaltrials.gov/study/NCT05811364",
"title": "The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease",
"has_exemption": false,
"start_date": "2023-10-17",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "W.L.Gore & Associates",
"sponsor_slug": "wlgore-associates",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06091865",
"publication_url": "https://clinicaltrials.gov/study/NCT06091865",
"title": "A Phase 3, Open Label, Randomized Study Comparing the Efficacy and Safety of Odronextamab (REGN1979), an Anti-CD20 × Anti-CD3 Bispecific Antibody, in Combination With CHOP (ODRO-CHOP) Versus Rituximab in Combination With CHOP (R-CHOP) in Previously Untreated Participants With Diffuse Large B-cell Lymphoma (DLBCL) (OLYMPIA-3)",
"has_exemption": false,
"start_date": "2023-12-13",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06213324",
"publication_url": "https://clinicaltrials.gov/study/NCT06213324",
"title": "Neural Circuit-Specific Mechanisms of Ketamine's Effect on Anhedonia and Anxiety in Depression Using Ultra-High Field 7-Tesla MRI",
"has_exemption": false,
"start_date": "2024-01-31",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Icahn School of Medicine at Mount Sinai",
"sponsor_slug": "icahn-school-of-medicine-at-mount-sinai",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06644768",
"publication_url": "https://clinicaltrials.gov/study/NCT06644768",
"title": "A Multicenter, Randomized, Open-Label, Phase 1b/2 Trial Of Valemetostat Tosylate Plus Pembrolizumab Vs Pembrolizumab Alone in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Whose Tumors Express PD-L1 With Tumor Proportion Score ≥50% Without Actionable Genomic Alterations",
"has_exemption": false,
"start_date": "2024-10-30",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Daiichi Sankyo",
"sponsor_slug": "daiichi-sankyo",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06877650",
"publication_url": "https://clinicaltrials.gov/study/NCT06877650",
"title": "A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-tumor Activity of JMT108 Injection in Participants With Advanced Malignant Tumors.",
"has_exemption": false,
"start_date": "2025-04-11",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Shanghai JMT-Bio Inc.",
"sponsor_slug": "shanghai-jmt-bio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06905054",
"publication_url": "https://clinicaltrials.gov/study/NCT06905054",
"title": "Peroxisome Proliferator-Activated Receptor Agonists to Prevent Primary Sclerosing Cholangitis Recurrence After Liver Transplantation",
"has_exemption": false,
"start_date": "2025-04-15",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07166757",
"publication_url": "https://clinicaltrials.gov/study/NCT07166757",
"title": "A Phase I/II Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of Human Allogeneic Induced Pluripotent Stem Cell-derived Dopaminergic Neural Progenitor Cell Injection in the Treatment of Early-onset Parkinson's Disease",
"has_exemption": false,
"start_date": "2025-09-22",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "XellSmart Bio-Pharmaceutical (Suzhou) Co., Ltd.",
"sponsor_slug": "xellsmart-bio-pharmaceutical-suzhou-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07169175",
"publication_url": "https://clinicaltrials.gov/study/NCT07169175",
"title": "A Multicenter, Open-label, Single-arm, Dose Escalation and Expansion, Phase I/IIa Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of SNUG01 in Adult Subjects With Amyotrophic Lateral Sclerosis (ALS)",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "SineuGene Therapeutics Co., Ltd.",
"sponsor_slug": "sineugene-therapeutics-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07115329",
"publication_url": "https://clinicaltrials.gov/study/NCT07115329",
"title": "Phase 2, Multicenter, Randomized, Double-Blind Evaluation of the Efficacy and Safety of Oral GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder",
"has_exemption": false,
"start_date": "2026-01-05",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Syndeio Biosciences, Inc",
"sponsor_slug": "syndeio-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07350174",
"publication_url": "https://clinicaltrials.gov/study/NCT07350174",
"title": "A Multicenter, Open-label, Randomized, Active-controlled, Phase 2a Study to Evaluate the Pharmacokinetics and Safety of Alpibectir/Ethionamide in Combination With the Standard Regimen in Patients With Tuberculosis Meningitis.",
"has_exemption": false,
"start_date": "2026-03-30",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "BioVersys AG",
"sponsor_slug": "bioversys-ag",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07594158",
"publication_url": "https://clinicaltrials.gov/study/NCT07594158",
"title": "A Multicenter, Open-label Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of ONO-2017 in Japanese Patients With Partial Onset Seizures Aged 2 to Under 18 Years.",
"has_exemption": false,
"start_date": "2026-06-10",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Ono Pharmaceutical Co. Ltd",
"sponsor_slug": "ono-pharmaceutical-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07403968",
"publication_url": "https://clinicaltrials.gov/study/NCT07403968",
"title": "An Open-Label, Single-Arm, Phase 2a Trial to Evaluate the Safety, Tolerability, PK, and Mechanism of Action of Zasocitinib (TAK-279) in Participants With Active Crohn's Disease",
"has_exemption": false,
"start_date": "2026-08-13",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07718737",
"publication_url": "https://clinicaltrials.gov/study/NCT07718737",
"title": "Open-Label, Global, Multicenter, Randomized, Phase 2/3 Study of AMT-116 Versus Investigator's Choice in Participants With Advanced or Metastatic Non-squamous EGFR-Wildtype Non-Small Cell Lung Cancer (NSCLC) With Progression on or After Platinum-Based Chemotherapy and Anti-PD-1/PD-L1 Immunotherapy",
"has_exemption": false,
"start_date": "2026-08-28",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Multitude Therapeutics Inc.",
"sponsor_slug": "multitude-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03514329",
"publication_url": "https://clinicaltrials.gov/study/NCT03514329",
"title": "Vapor Ablation for Localized Cancer Lesions of the Lung - A Clinical Feasibility Definitive Treatment Study",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Uptake Medical Technology, Inc.",
"sponsor_slug": "uptake-medical-technology-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07642284",
"publication_url": "https://clinicaltrials.gov/study/NCT07642284",
"title": "A Prospective, Parallel-group, Randomized Clinical Investigation Evaluating Performance and Safety of the AH Plus Jet® Sealing Materials Used in Single-cone Technique for Single Visit Endodontic Treatment. A 2-year Follow-up Study",
"has_exemption": false,
"start_date": "2026-09-09",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Dentsply Sirona Implants and Consumables",
"sponsor_slug": "dentsply-sirona-implants-and-consumables",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07859553",
"publication_url": "https://clinicaltrials.gov/study/NCT07859553",
"title": "Powered vs Manual Toothbrush Use: Its Effect on Caries Risk in Pre-Adolescents, A Pilot Study",
"has_exemption": false,
"start_date": "2026-10-28",
"completion_date": "2028-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan",
"sponsor_slug": "university-of-michigan",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03414502",
"publication_url": "https://clinicaltrials.gov/study/NCT03414502",
"title": "Treatment of Rheumatoid Arthritis With Disease-modifying Antirheumatic Drugs (DMARDs): Predictors of Response",
"has_exemption": false,
"start_date": "2007-12-10",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Nebraska",
"sponsor_slug": "university-of-nebraska",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02089607",
"publication_url": "https://clinicaltrials.gov/study/NCT02089607",
"title": "Clinical Outcomes and Quality of Life Measures in Patients Treated for Complex Abdominal, Thoracoabdominal and Aortic Arch Aneurysms or Dissections With Fenestrated and Branched Stent Grafts",
"has_exemption": false,
"start_date": "2014-03-31",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Gustavo S. Oderich",
"sponsor_slug": "gustavo-s-oderich",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT01954992",
"publication_url": "https://clinicaltrials.gov/study/NCT01954992",
"title": "A Randomized Phase 3 Study of the Efficacy and Safety of Glufosfamide Compared With Fluorouracil (5-FU) in Patients With Metastatic Pancreatic Adenocarcinoma Previously Treated With Gemcitabine",
"has_exemption": false,
"start_date": "2014-04-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eleison Pharmaceuticals LLC.",
"sponsor_slug": "eleison-pharmaceuticals-llc",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02174549",
"publication_url": "https://clinicaltrials.gov/study/NCT02174549",
"title": "Phase I Dose-Escalating Study of Combining Intravenous Tirapazamine and Transarterial Embolization (TAE) in Liver Cancer",
"has_exemption": false,
"start_date": "2014-09-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Teclison Ltd.",
"sponsor_slug": "teclison-ltd",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02324387",
"publication_url": "https://clinicaltrials.gov/study/NCT02324387",
"title": "Assessment of the Tumor Response to Neoadjuvant Chemotherapy in Women With Locoregional Invasive Breast Cancer Using Tc99m Sestamibi Molecular Breast Imaging: A Prospective Study",
"has_exemption": false,
"start_date": "2015-06-15",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02710968",
"publication_url": "https://clinicaltrials.gov/study/NCT02710968",
"title": "Study of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Fetuses With Severe Left Congenital Diaphragmatic Hernia (CDH)",
"has_exemption": false,
"start_date": "2015-08-31",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02629809",
"publication_url": "https://clinicaltrials.gov/study/NCT02629809",
"title": "First-Line Therapy With Ibrutinib, Fludarabine, Cyclophosphamide, and Obinutuzumab (GA-101) (iFCG) for Patients With Chronic Lymphocytic Leukemia (CLL) With Mutated IGHV Gene and Non-Del(17p)",
"has_exemption": false,
"start_date": "2016-03-18",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02742883",
"publication_url": "https://clinicaltrials.gov/study/NCT02742883",
"title": "A Phase 2 Study of Atengenal (A-10) and Astugenal (AS2-1) in Diffuse, Intrinsic Pontine Glioma (DIPG)",
"has_exemption": false,
"start_date": "2016-04-13",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Burzynski Research Institute",
"sponsor_slug": "burzynski-research-institute",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02703623",
"publication_url": "https://clinicaltrials.gov/study/NCT02703623",
"title": "A Dynamic Allocation Modular Sequential Trial of Approved and Promising Therapies in Men With Metastatic Castrate Resistant Prostate Cancer",
"has_exemption": false,
"start_date": "2016-05-18",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03011684",
"publication_url": "https://clinicaltrials.gov/study/NCT03011684",
"title": "Fertility Preservation Using Tamoxifen and Letrozole in Estrogen Sensitive Tumors Trial",
"has_exemption": false,
"start_date": "2016-07-21",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02724579",
"publication_url": "https://clinicaltrials.gov/study/NCT02724579",
"title": "A Phase 2 Study of Reduced Therapy for Newly Diagnosed Average-Risk WNT-Driven Medulloblastoma Patients",
"has_exemption": false,
"start_date": "2017-11-17",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03682289",
"publication_url": "https://clinicaltrials.gov/study/NCT03682289",
"title": "Phase II Trial of Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Selected Solid Tumor Malignancies",
"has_exemption": false,
"start_date": "2019-01-17",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Rahul Aggarwal",
"sponsor_slug": "rahul-aggarwal",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03865290",
"publication_url": "https://clinicaltrials.gov/study/NCT03865290",
"title": "Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia",
"has_exemption": false,
"start_date": "2019-04-02",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03998254",
"publication_url": "https://clinicaltrials.gov/study/NCT03998254",
"title": "A Phase 3 Randomized, Double-Blinded, Controlled With GARDASIL® Efficacy, Immunogenicity and Safety Study of V503 [a 9-Valent HPV Vaccine] in Chinese Women 20 to 45 Years of Age",
"has_exemption": false,
"start_date": "2019-06-26",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04099056",
"publication_url": "https://clinicaltrials.gov/study/NCT04099056",
"title": "Brain Stimulation Studies of Decision-making Using Repetitive Transcranial Magnetic Stimulation (rTMS) and Temporal Interference (TI)",
"has_exemption": false,
"start_date": "2019-11-11",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04248452",
"publication_url": "https://clinicaltrials.gov/study/NCT04248452",
"title": "A Phase III Study of Consolidative Radiotherapy in Patients With Oligometastatic HER2 Negative Esophageal and Gastric Adenocarcinoma (EGA)",
"has_exemption": false,
"start_date": "2020-05-26",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ECOG-ACRIN Cancer Research Group",
"sponsor_slug": "ecog-acrin-cancer-research-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04560803",
"publication_url": "https://clinicaltrials.gov/study/NCT04560803",
"title": "Using Autologous Epidermal Skin Micrografts to Improve Healing In Radiation Wounds: A Pilot Study",
"has_exemption": false,
"start_date": "2021-01-19",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04230356",
"publication_url": "https://clinicaltrials.gov/study/NCT04230356",
"title": "A Randomized Trial of Scheduled Versus Treatment Administration of Donor-Derived Viral Specific T-cells (VSTs) for Control of Viral Infections After Allogeneic Stem Cell Transplant",
"has_exemption": false,
"start_date": "2021-01-27",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Hospital Medical Center, Cincinnati",
"sponsor_slug": "childrens-hospital-medical-center-cincinnati",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04408638",
"publication_url": "https://clinicaltrials.gov/study/NCT04408638",
"title": "A Phase III, Open-Label, Multicenter, Randomized Study Evaluating the Efficacy and Safety of Glofitamab in Combination With Gemcitabine Plus Oxaliplatin Versus Rituximab in Combination With Gemcitabine and Oxaliplatin in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma",
"has_exemption": false,
"start_date": "2021-02-23",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04696029",
"publication_url": "https://clinicaltrials.gov/study/NCT04696029",
"title": "Phase II Trial of Eflornithine/DFMO as Maintenance Therapy for Molecular High Risk/Very High Risk and Relapsed/Refractory Medulloblastoma",
"has_exemption": false,
"start_date": "2021-03-29",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Giselle Sholler",
"sponsor_slug": "giselle-sholler",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04486833",
"publication_url": "https://clinicaltrials.gov/study/NCT04486833",
"title": "A Phase 1/2 Open-Label, Dose-Escalation and Clinical Response Study of Quaratusugene Ozeplasmid in Combination With Osimertinib in Patients With Advanced, Metastatic EGFR-Mutant, Metastatic Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2021-09-03",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Genprex, Inc.",
"sponsor_slug": "genprex-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05150704",
"publication_url": "https://clinicaltrials.gov/study/NCT05150704",
"title": "Single Blind Randomized Controlled Trial to Assess the Safety and Efficacy of High Dose Pulse Intravenous Corticosteroid Therapy to Treat Patients With Complicated/Fulminant Acute Myocarditis",
"has_exemption": false,
"start_date": "2021-10-07",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Niguarda Hospital",
"sponsor_slug": "niguarda-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04982419",
"publication_url": "https://clinicaltrials.gov/study/NCT04982419",
"title": "Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial",
"has_exemption": false,
"start_date": "2021-11-01",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04840602",
"publication_url": "https://clinicaltrials.gov/study/NCT04840602",
"title": "A Phase II Randomized Study Comparing BTK Inhibitors (Ibrutinib Plus Rituximab or Zanubrutinib Alone) vs. BCL-2 Inhibitor (Venetoclax) and Rituximab in Previously Untreated Waldenström's Macroglobulinemia (WM) / Lymphoplasmacytic Lymphoma (LPL)",
"has_exemption": false,
"start_date": "2022-01-05",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04879043",
"publication_url": "https://clinicaltrials.gov/study/NCT04879043",
"title": "A Phase 1/2a, First-in-human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of HDP-101 in Patients With Plasma Cell Disorders Including Multiple Myeloma",
"has_exemption": false,
"start_date": "2022-02-07",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Heidelberg Pharma AG",
"sponsor_slug": "heidelberg-pharma-ag",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04977180",
"publication_url": "https://clinicaltrials.gov/study/NCT04977180",
"title": "Phase II Trial of Cardioprotective Prophylaxis With Combination of Beta Blocker and Angiotensin-Converting Enzyme Inhibitors During Intensive Chemotherapy for Patients With Newly Diagnosed Acute Myeloid Leukemia",
"has_exemption": false,
"start_date": "2022-03-04",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Virginia",
"sponsor_slug": "university-of-virginia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05269381",
"publication_url": "https://clinicaltrials.gov/study/NCT05269381",
"title": "A Phase I/II Study of Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab in Advanced Solid Tumors (PNeoVCA)",
"has_exemption": false,
"start_date": "2022-03-31",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05416307",
"publication_url": "https://clinicaltrials.gov/study/NCT05416307",
"title": "A Multipart, Open-label, Single-arm, Multicenter Study to Evaluate the Safety, Efficacy and Pharmacokinetics of ELA026 in Participants With Secondary Hemophagocytic Lymphohistiocytosis (sHLH)",
"has_exemption": false,
"start_date": "2022-05-19",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Electra Therapeutics Inc.",
"sponsor_slug": "electra-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05376267",
"publication_url": "https://clinicaltrials.gov/study/NCT05376267",
"title": "Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)",
"has_exemption": false,
"start_date": "2022-08-05",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan",
"sponsor_slug": "university-of-michigan",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05523947",
"publication_url": "https://clinicaltrials.gov/study/NCT05523947",
"title": "A Phase 1/2, Open-label, Multicenter, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Anti-tumor Activity of YH32367 in Patients With HER2-Positive Locally Advanced or Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2022-08-26",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yuhan Corporation",
"sponsor_slug": "yuhan-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05504291",
"publication_url": "https://clinicaltrials.gov/study/NCT05504291",
"title": "Intravitreal Melphalan for Intraocular Retinoblastoma",
"has_exemption": false,
"start_date": "2022-11-04",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05581303",
"publication_url": "https://clinicaltrials.gov/study/NCT05581303",
"title": "A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing the Impact of Olpasiran on Major Cardiovascular Events in Participants With Atherosclerotic Cardiovascular Disease and Elevated Lipoprotein(a)",
"has_exemption": false,
"start_date": "2022-12-14",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Amgen",
"sponsor_slug": "amgen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05549297",
"publication_url": "https://clinicaltrials.gov/study/NCT05549297",
"title": "Phase 2/3 Randomized Study of Tebentafusp as Monotherapy and in Combination With Pembrolizumab Versus Investigator's Choice in HLA-A*02:01-positive Participants With Previously Treated Advanced Melanoma (TEBE-AM)",
"has_exemption": false,
"start_date": "2022-12-19",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Immunocore Ltd",
"sponsor_slug": "immunocore-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05723198",
"publication_url": "https://clinicaltrials.gov/study/NCT05723198",
"title": "A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of Baricitinib in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata",
"has_exemption": false,
"start_date": "2023-02-27",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05711394",
"publication_url": "https://clinicaltrials.gov/study/NCT05711394",
"title": "A Phase 3, Multicenter, 12-Week, Double Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Atogepant for the Preventive Treatment of Episodic Migraine in Pediatric Subjects 6-17 Years of Age.",
"has_exemption": false,
"start_date": "2023-05-01",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05764720",
"publication_url": "https://clinicaltrials.gov/study/NCT05764720",
"title": "A Prospective Trial of Stereotactic Adaptive Radiation Therapy for Borderline Resectable/Locally Advanced Pancreatic Cancer: An Individualized Approach to Minimizing Gastrointestinal Toxicity (ARTIA-Pancreas)",
"has_exemption": false,
"start_date": "2023-05-14",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Varian, a Siemens Healthineers Company",
"sponsor_slug": "varian-a-siemens-healthineers-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05889182",
"publication_url": "https://clinicaltrials.gov/study/NCT05889182",
"title": "A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate Efficacy and Safety of Upadacitinib in Adult and Adolescent Subjects With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy",
"has_exemption": false,
"start_date": "2023-06-21",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05871372",
"publication_url": "https://clinicaltrials.gov/study/NCT05871372",
"title": "Intracranial Investigation of Neural Circuity Underlying Human Mood",
"has_exemption": false,
"start_date": "2023-07-03",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Baylor College of Medicine",
"sponsor_slug": "baylor-college-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05796440",
"publication_url": "https://clinicaltrials.gov/study/NCT05796440",
"title": "An Extension Study to Monitor Long-Term Safety of LUM-201 Treatment in Children With Idiopathic Growth Hormone Deficiency",
"has_exemption": false,
"start_date": "2023-08-01",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Lumos Pharma",
"sponsor_slug": "lumos-pharma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05798923",
"publication_url": "https://clinicaltrials.gov/study/NCT05798923",
"title": "A Phase 2, Randomized, Double-Blind, Multi-Dose, Placebo-Controlled Study to Evaluate the Efficacy and Safety of LAM-001 in Adults With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)",
"has_exemption": false,
"start_date": "2023-08-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "IRulya Therapeutics Inc.",
"sponsor_slug": "irulya-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06019949",
"publication_url": "https://clinicaltrials.gov/study/NCT06019949",
"title": "Neuromodulatory Rehabilitation for Respiratory Motor Function in Individuals With Chronic Spinal Cord Injury",
"has_exemption": false,
"start_date": "2023-09-10",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Louisville",
"sponsor_slug": "university-of-louisville",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05848713",
"publication_url": "https://clinicaltrials.gov/study/NCT05848713",
"title": "AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia",
"has_exemption": false,
"start_date": "2023-10-10",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Manitoba",
"sponsor_slug": "university-of-manitoba",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06189963",
"publication_url": "https://clinicaltrials.gov/study/NCT06189963",
"title": "A Phase I/IIa, Study to Evaluate the Safety, Tolerability and Exploratory Efficacy of SNK01 in Participants With Moderate Alzheimer's Disease",
"has_exemption": false,
"start_date": "2023-11-21",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NKGen Biotech, Inc.",
"sponsor_slug": "nkgen-biotech-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06149403",
"publication_url": "https://clinicaltrials.gov/study/NCT06149403",
"title": "A Multi-center, Randomized, Active Controlled Clinical Trial to Evaluate the Efficacy and Safety of OTL-203 in Subjects With Mucopolysaccharidosis Type I, Hurler Syndrome (MPS-IH) Compared to Standard of Care With Allogeneic Hematopoietic Stem Cell Transplantation (Allo-HSCT)",
"has_exemption": false,
"start_date": "2023-12-11",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Orchard Therapeutics",
"sponsor_slug": "orchard-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06118411",
"publication_url": "https://clinicaltrials.gov/study/NCT06118411",
"title": "A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Efficacy, Safety, and Tolerability of Upadacitinib in Adult and Adolescent Subjects With Non-Segmental Vitiligo Who Are Eligible for Systemic Therapy",
"has_exemption": false,
"start_date": "2023-12-19",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06109467",
"publication_url": "https://clinicaltrials.gov/study/NCT06109467",
"title": "A Phase II Study Of Neratinib In Combination With Chemotherapy/Trastuzumab/Pembrolizumab In HER2 Overexpressing Gastroesophageal Cancers",
"has_exemption": false,
"start_date": "2024-01-12",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06133101",
"publication_url": "https://clinicaltrials.gov/study/NCT06133101",
"title": "Impact of Soymilk on Liver Disease Severity of Children With Non-alcoholic Fatty Liver Disease (NAFLD)",
"has_exemption": false,
"start_date": "2024-01-15",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Marialena Mouzaki",
"sponsor_slug": "marialena-mouzaki",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06225596",
"publication_url": "https://clinicaltrials.gov/study/NCT06225596",
"title": "A Randomized Open-Label Phase 2/3 Study of BT8009 as Monotherapy or in Combination in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)",
"has_exemption": false,
"start_date": "2024-01-24",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "BicycleTx Limited",
"sponsor_slug": "bicycletx-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05100641",
"publication_url": "https://clinicaltrials.gov/study/NCT05100641",
"title": "Randomized Phase 3 Trial of Standard Care Plus AV-GBM-1 vs Autologous Monocytes as Adjunctive Therapy Following Primary Surgery Plus Concurrent Radiation-temozolomide in Patients With Newly Diagnosed Glioblastoma",
"has_exemption": false,
"start_date": "2024-01-31",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Aivita Biomedical, Inc.",
"sponsor_slug": "aivita-biomedical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06108934",
"publication_url": "https://clinicaltrials.gov/study/NCT06108934",
"title": "A Prospective, Pre-market, Multi-center Evaluation of the Clinical Outcomes of the Insignia Hip Stem in Total Hip Arthroplasty (THA)",
"has_exemption": false,
"start_date": "2024-02-22",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stryker Australia Pty Ltd.",
"sponsor_slug": "stryker-australia-pty-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06223867",
"publication_url": "https://clinicaltrials.gov/study/NCT06223867",
"title": "Evaluation of Efficacy, Effectiveness, and Implementation of Jaspr Health's Digital Platform in Emergency Department for Patients With Suicidal Risk- Part A: Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2024-02-23",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Massachusetts, Worcester",
"sponsor_slug": "university-of-massachusetts-worcester",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05692024",
"publication_url": "https://clinicaltrials.gov/study/NCT05692024",
"title": "COMMENCER: COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER",
"has_exemption": false,
"start_date": "2024-03-21",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06309264",
"publication_url": "https://clinicaltrials.gov/study/NCT06309264",
"title": "Benefits of Speech-based Audiometry and Low-gain Hearing Aids for Blast-exposed Veterans",
"has_exemption": false,
"start_date": "2024-04-01",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05823532",
"publication_url": "https://clinicaltrials.gov/study/NCT05823532",
"title": "Targeting Inflammation-Induced Changes in Brain Reward Signaling and Motivational Deficits in Patients With Schizophrenia Using an Anti-Inflammatory Challenge.",
"has_exemption": false,
"start_date": "2024-04-18",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05861986",
"publication_url": "https://clinicaltrials.gov/study/NCT05861986",
"title": "A Phase IV Open-Label Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Patients With Spinal Muscular Atrophy After Gene Therapy",
"has_exemption": false,
"start_date": "2024-05-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06718764",
"publication_url": "https://clinicaltrials.gov/study/NCT06718764",
"title": "Evaluating the Feasibility of Utilizing a Novel Brain Activity Monitor in the Neurosciences Intensive Care Unit",
"has_exemption": false,
"start_date": "2024-07-08",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Icahn School of Medicine at Mount Sinai",
"sponsor_slug": "icahn-school-of-medicine-at-mount-sinai",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06483334",
"publication_url": "https://clinicaltrials.gov/study/NCT06483334",
"title": "A Phase 1/2 Randomized, Umbrella Study to Evaluate the Efficacy and Safety of MK-2870 Plus Enfortumab Vedotin (EV) With and Without Pembrolizumab, as Treatment for Participants With Advanced Urothelial Carcinoma (KEYMAKER-U04): Substudy 04C",
"has_exemption": false,
"start_date": "2024-07-17",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06107062",
"publication_url": "https://clinicaltrials.gov/study/NCT06107062",
"title": "Hemp-derived Cannabidiol for the Treatment of Cannabis Use Disorder: A Double-blind Placebo-controlled Randomized Trial",
"has_exemption": false,
"start_date": "2024-07-26",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Boulder",
"sponsor_slug": "university-of-colorado-boulder",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06428019",
"publication_url": "https://clinicaltrials.gov/study/NCT06428019",
"title": "A Prospective, Open-Label, Phase IIb/III Study to Evaluate the Risk of TLS and Optimization of the Initiation of Venetoclax in Combination With Obinutuzumab or Acalabrutinib With Different Ramp- Up Periods in Previously Untreated Subjects With CLL",
"has_exemption": false,
"start_date": "2024-08-05",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06442566",
"publication_url": "https://clinicaltrials.gov/study/NCT06442566",
"title": "Sequential Trial of Adding Buprenorphine, Cognitive Behavioral Treatment, and Transcranial Magnetic Stimulation to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain (ACTION)",
"has_exemption": false,
"start_date": "2024-08-12",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University of South Carolina",
"sponsor_slug": "medical-university-of-south-carolina",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06508658",
"publication_url": "https://clinicaltrials.gov/study/NCT06508658",
"title": "A Phase 3, Multicenter, Randomized, Open-Label Study of Epcoritamab Plus Lenalidomide Compared to Rituximab Plus Gemcitabine and Oxaliplatin in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma",
"has_exemption": false,
"start_date": "2024-08-13",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Genmab",
"sponsor_slug": "genmab",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05861999",
"publication_url": "https://clinicaltrials.gov/study/NCT05861999",
"title": "A Phase IV Open-Label Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy",
"has_exemption": false,
"start_date": "2024-08-14",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06096116",
"publication_url": "https://clinicaltrials.gov/study/NCT06096116",
"title": "Phase 3, Double-blind, Placebo-controlled, Multicentre Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass",
"has_exemption": false,
"start_date": "2024-08-21",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Octapharma",
"sponsor_slug": "octapharma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05667701",
"publication_url": "https://clinicaltrials.gov/study/NCT05667701",
"title": "Soy Isoflavones For Inner City Infants At Risk For Asthma (SIRA) Study",
"has_exemption": false,
"start_date": "2024-09-18",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Rajesh Kumar",
"sponsor_slug": "rajesh-kumar",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06053814",
"publication_url": "https://clinicaltrials.gov/study/NCT06053814",
"title": "A Phase 1/2, First in Human, Multiple-dose, 2-part Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NS-050/NCNP-03 in Boys With Duchenne Muscular Dystrophy (DMD)",
"has_exemption": false,
"start_date": "2024-09-18",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NS Pharma, Inc.",
"sponsor_slug": "ns-pharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06184750",
"publication_url": "https://clinicaltrials.gov/study/NCT06184750",
"title": "Refining Tamoxifen Dose for Premenopausal Breast Cancer Risk Reduction (RENAISSANCE): A Phase II Single Arm Trial",
"has_exemption": false,
"start_date": "2024-09-27",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06679270",
"publication_url": "https://clinicaltrials.gov/study/NCT06679270",
"title": "An Open-label Extension of APG-20 Study to Evaluate the Long-term Safety and Efficacy of Daily Subcutaneous Metreleptin Treatment in Subjects With Partial Lipodystrophy",
"has_exemption": false,
"start_date": "2024-10-14",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Chiesi Farmaceutici S.p.A.",
"sponsor_slug": "chiesi-farmaceutici-spa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04530058",
"publication_url": "https://clinicaltrials.gov/study/NCT04530058",
"title": "The Effects of Metformin on Morbidity and Mortality in Elderly Patients- a Prospective Randomized Control Trial (RCT)",
"has_exemption": false,
"start_date": "2024-11-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hamilton Health Sciences Corporation",
"sponsor_slug": "hamilton-health-sciences-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06679946",
"publication_url": "https://clinicaltrials.gov/study/NCT06679946",
"title": "An Open-Label Extension Study to Assess the Safety and Efficacy of Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy (ATTR Amyloidosis With Cardiomyopathy)",
"has_exemption": false,
"start_date": "2024-12-03",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Alnylam Pharmaceuticals",
"sponsor_slug": "alnylam-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06381154",
"publication_url": "https://clinicaltrials.gov/study/NCT06381154",
"title": "MC230404 Photodynamic Priming to Facilitate Immunologic Activity of Anti-PD1 in Patients With Pancreatic Cancer",
"has_exemption": false,
"start_date": "2024-12-06",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06282809",
"publication_url": "https://clinicaltrials.gov/study/NCT06282809",
"title": "The HistoSonics Edison™ System for Treatment of Pancreatic Adenocarcinoma Using Histotripsy",
"has_exemption": false,
"start_date": "2024-12-10",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "HistoSonics, Inc.",
"sponsor_slug": "histosonics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05427695",
"publication_url": "https://clinicaltrials.gov/study/NCT05427695",
"title": "Topical Probiotic Sinus Irrigations for the Treatment of Chronic Rhinosinusitis: a Double Blinded Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2025-02-05",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Illinois at Chicago",
"sponsor_slug": "university-of-illinois-at-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06689878",
"publication_url": "https://clinicaltrials.gov/study/NCT06689878",
"title": "Mobile Cognitive Behavioral Therapy for Stroke",
"has_exemption": false,
"start_date": "2025-02-25",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06855212",
"publication_url": "https://clinicaltrials.gov/study/NCT06855212",
"title": "A Phase II Study of Neoadjuvant Cetuximab and Cemiplimab in Patients Undergoing Surgery for Head and Neck Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2025-02-26",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05790239",
"publication_url": "https://clinicaltrials.gov/study/NCT05790239",
"title": "A Randomized, Double-Blind, Single-Site Phase II 2-Arm Study to Compare the Safety and Preliminary Efficacy of Manualized MDMA-Assisted Therapy to Low Dose D-Amphetamine Assisted Therapy in Veterans For The Treatment of Moderate to Severe PTSD",
"has_exemption": false,
"start_date": "2025-03-01",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stephen Robert Marder",
"sponsor_slug": "stephen-robert-marder",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06830044",
"publication_url": "https://clinicaltrials.gov/study/NCT06830044",
"title": "A Randomized, Double-Blind, Placebo-controlled Multicenter Study to Assess the Efficacy and Safety of Milsaperidone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder",
"has_exemption": false,
"start_date": "2025-03-03",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanda Pharmaceuticals",
"sponsor_slug": "vanda-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06689085",
"publication_url": "https://clinicaltrials.gov/study/NCT06689085",
"title": "Open-Label, Multiple-Dose, 52-Week Study + 24-Month Long-Term Safety Extension to Evaluate the Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Deficiency or Absence of Endogenous Testosterone Due to Primary or Secondary Hypogonadism",
"has_exemption": false,
"start_date": "2025-03-07",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Halozyme Therapeutics",
"sponsor_slug": "halozyme-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06311214",
"publication_url": "https://clinicaltrials.gov/study/NCT06311214",
"title": "Optimizing Antibody-Drug Conjugate Therapy Through Molecular Analysis for Therapy Choice (ADC MATCH)",
"has_exemption": false,
"start_date": "2025-03-18",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06812832",
"publication_url": "https://clinicaltrials.gov/study/NCT06812832",
"title": "Simethicone as Part of an Enhanced Recovery After Surgery (ERAS) Protocol",
"has_exemption": false,
"start_date": "2025-04-08",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Madigan Army Medical Center",
"sponsor_slug": "madigan-army-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06820463",
"publication_url": "https://clinicaltrials.gov/study/NCT06820463",
"title": "A Phase 2, Open-Label, Randomized, Master Protocol Study to Evaluate Safety and Efficacy of Multiple Treatment Combinations With Telisotuzumab Adizutecan in Subjects With Metastatic Colorectal Cancer",
"has_exemption": false,
"start_date": "2025-04-24",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06414460",
"publication_url": "https://clinicaltrials.gov/study/NCT06414460",
"title": "A Phase 1/2, Open-Label, Multicenter, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics/Pharmacodynamics, and Preliminary Efficacy of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2025-04-25",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "InSilico Medicine Hong Kong Limited",
"sponsor_slug": "insilico-medicine-hong-kong-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06579196",
"publication_url": "https://clinicaltrials.gov/study/NCT06579196",
"title": "Evaluation of Trabedersen (OT-101) With Pembrolizumab in Patients With Newly Diagnosed Advanced Non-Small Cell Lung Cancer and Positive PD-L1",
"has_exemption": false,
"start_date": "2025-05-12",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Nebraska",
"sponsor_slug": "university-of-nebraska",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06702553",
"publication_url": "https://clinicaltrials.gov/study/NCT06702553",
"title": "Effect of Inhaled Nitric Oxide on Major Adverse Events Requiring Intensive Life Support in Adults Undergoing Cardiac Surgery With Cardiopulmonary Bypass: A Phase III, Double-Blind, Multicenter, Randomized Controlled Trial (Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary Bypass, the NORISC Trial)",
"has_exemption": false,
"start_date": "2025-05-19",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Xijing Hospital",
"sponsor_slug": "xijing-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06485843",
"publication_url": "https://clinicaltrials.gov/study/NCT06485843",
"title": "An Open Label Phase IIb Study to Evaluate Safety and Tolerability of OA-SYS in Subjects With Moderate to Severe Osteoarthritis of the Knee Joint",
"has_exemption": false,
"start_date": "2025-05-21",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ageless Biotech, Inc.",
"sponsor_slug": "ageless-biotech-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06676579",
"publication_url": "https://clinicaltrials.gov/study/NCT06676579",
"title": "A Multi-Center, Phase II, Open Label, Randomized Trial Evaluating the Efficacy and Safety of Complement 5a Receptor Antagonist Avacopan in Crescentic IgA Nephropathy",
"has_exemption": false,
"start_date": "2025-06-09",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06340568",
"publication_url": "https://clinicaltrials.gov/study/NCT06340568",
"title": "A Phase III, Randomized, Multi-site, Open-label Trial of BNT323/DB-1303 Versus Investigator's Choice of Chemotherapy in Previously Treated Patients With HER2- Expressing Recurrent Endometrial Cancer",
"has_exemption": false,
"start_date": "2025-06-10",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Biontech SE",
"sponsor_slug": "biontech-se",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07075718",
"publication_url": "https://clinicaltrials.gov/study/NCT07075718",
"title": "Phase 2 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant",
"has_exemption": false,
"start_date": "2025-06-12",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Glaukos Corporation",
"sponsor_slug": "glaukos-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07778823",
"publication_url": "https://clinicaltrials.gov/study/NCT07778823",
"title": "AR-CPR: Large-Scale Simulation-Based Testing of a Novel Augmented Reality Point of Care Chest Compression Feedback System",
"has_exemption": false,
"start_date": "2025-06-29",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06951594",
"publication_url": "https://clinicaltrials.gov/study/NCT06951594",
"title": "Iowa Cochlear Implant Clinical Research Center Study on Robotic-Assisted Versus Manual Electrode Array Insertion",
"has_exemption": false,
"start_date": "2025-06-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Bruce J Gantz",
"sponsor_slug": "bruce-j-gantz",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07045909",
"publication_url": "https://clinicaltrials.gov/study/NCT07045909",
"title": "A Phase 2, Open-label, Multicenter Multi-cohort Study to Evaluate the Efficacy and Safety of Anitocabtagene Autoleucel in Participants With Newly Diagnosed Multiple Myeloma",
"has_exemption": false,
"start_date": "2025-06-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "PETHEMA Foundation",
"sponsor_slug": "pethema-foundation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06356155",
"publication_url": "https://clinicaltrials.gov/study/NCT06356155",
"title": "A Phase II, Open-label, Single-arm, Multi-center Study of Neoadjuvant Enfortumab Vedotin and Pembrolizumab in Upper Tract Urothelial Cancer (NEPTUNE)",
"has_exemption": false,
"start_date": "2025-07-22",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan Rogel Cancer Center",
"sponsor_slug": "university-of-michigan-rogel-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06850805",
"publication_url": "https://clinicaltrials.gov/study/NCT06850805",
"title": "A 12-Week Randomized, Double-Blind, Placebo-Controlled, Multicenter Study Evaluating the Efficacy and Safety of Intranasal Administration of 186 mcg of OPN-375 Twice a Day (BID) in Adolescent Subjects With Chronic Rhinosinusitis Without Nasal Polyps",
"has_exemption": false,
"start_date": "2025-07-28",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Optinose US Inc.",
"sponsor_slug": "optinose-us-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07070232",
"publication_url": "https://clinicaltrials.gov/study/NCT07070232",
"title": "A Phase I/II, Open-label, Adaptive Two-part Trial to Evaluate the Safety, Efficacy, Optimal Dose and Pharmacokinetics of BNT326 as Monotherapy and in Combination With Cancer Immunotherapies in Participants With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2025-08-12",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Biontech SE",
"sponsor_slug": "biontech-se",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06959524",
"publication_url": "https://clinicaltrials.gov/study/NCT06959524",
"title": "AGENT DCB STANCE: AGENT Drug-Coated Balloon for STent AvoidANCE in PCI for De Novo Coronary Artery Disease",
"has_exemption": false,
"start_date": "2025-08-21",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Scientific Corporation",
"sponsor_slug": "boston-scientific-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07114380",
"publication_url": "https://clinicaltrials.gov/study/NCT07114380",
"title": "Investigation of Cold Snare Polypectomy for Removing 10-20 mm 0-Ip Colorectal Polyp: One Feasibility and Safety Study",
"has_exemption": false,
"start_date": "2025-08-25",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Taiwan University Hospital",
"sponsor_slug": "national-taiwan-university-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07023835",
"publication_url": "https://clinicaltrials.gov/study/NCT07023835",
"title": "A Phase 2b, Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Usnoflast Administered to Adult Subjects With ALS",
"has_exemption": false,
"start_date": "2025-09-17",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Zydus Therapeutics Inc.",
"sponsor_slug": "zydus-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07202884",
"publication_url": "https://clinicaltrials.gov/study/NCT07202884",
"title": "A Master Protocol to Investigate the Efficacy and Safety of Orforglipron Tablet Once Daily Compared With Placebo in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight",
"has_exemption": false,
"start_date": "2025-09-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07181837",
"publication_url": "https://clinicaltrials.gov/study/NCT07181837",
"title": "A Multi-Center, Open-label, Phase 1/2 Trial of the Safety and Efficacy of MVX-220 Gene Therapy Administered by Intra-Cisterna Magna Injection to Participants With Angelman Syndrome",
"has_exemption": false,
"start_date": "2025-10-29",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "MavriX Bio, LLC",
"sponsor_slug": "mavrix-bio-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06699121",
"publication_url": "https://clinicaltrials.gov/study/NCT06699121",
"title": "A Phase 2 Randomized, Double Blind, Placebo Controlled, Parallel Study Evaluating the Safety and Efficacy of LB P8 in Patients With Primary Sclerosing Cholangitis (PSC)",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "LISCure Biosciences",
"sponsor_slug": "liscure-biosciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06917313",
"publication_url": "https://clinicaltrials.gov/study/NCT06917313",
"title": "A Randomized Phase II Study to Evaluate the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy",
"has_exemption": false,
"start_date": "2025-12-05",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06910943",
"publication_url": "https://clinicaltrials.gov/study/NCT06910943",
"title": "A Phase 2b/3 Randomized Open-Label Dose-Selection Study With Open-Label Extension and Randomized Double-Blind, Placebo-Controlled Study With Open-Label Extension to Evaluate the Safety and Efficacy of Choline Chloride for Injection (Low Dose and High Dose) Versus Placebo in Adolescents and Adults With Intestinal Failure Receiving Long-Term Parenteral Support",
"has_exemption": false,
"start_date": "2025-12-10",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Protara Therapeutics",
"sponsor_slug": "protara-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07219602",
"publication_url": "https://clinicaltrials.gov/study/NCT07219602",
"title": "A Placebo-Controlled, Double-Blind, Randomized, Phase 3 Study to Evaluate the Effect of Obicetrapib 10 mg and Ezetimibe 10 mg Fixed-Dose Combination or Obicetrapib 10 mg Daily on Top of Guideline-Recommended Lipid-Lowering Therapy in Participants With Type 2 Diabetes and/or Metabolic Syndrome (RUBENS Trial)",
"has_exemption": false,
"start_date": "2025-12-11",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NewAmsterdam Pharma",
"sponsor_slug": "newamsterdam-pharma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06722183",
"publication_url": "https://clinicaltrials.gov/study/NCT06722183",
"title": "FUTURE Platform Trial - A Phase II Platform Trial of Futibatinib in Combination With (Chemo)Immunotherapy in Colorectal Cancer and Other Solid Tumor Entities",
"has_exemption": false,
"start_date": "2025-12-16",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest",
"sponsor_slug": "institut-fur-klinische-krebsforschung-ikf-gmbh-at-krankenhaus-nordwest",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07225712",
"publication_url": "https://clinicaltrials.gov/study/NCT07225712",
"title": "A Multicenter, Uncontrolled, Open-label Trial to Evaluate the Tolerability, Safety, and Efficacy of Long-term Administration of SEP-363856 in Patients With Schizophrenia",
"has_exemption": false,
"start_date": "2025-12-22",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Otsuka Pharmaceutical Co., Ltd.",
"sponsor_slug": "otsuka-pharmaceutical-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07284979",
"publication_url": "https://clinicaltrials.gov/study/NCT07284979",
"title": "A Phase 3, Randomized, Active- and Placebo-Controlled, Partially-Blinded Study to Compare the Efficacy and Safety of KAI-9531 Administered Once Weekly Versus Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes",
"has_exemption": false,
"start_date": "2025-12-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kailera",
"sponsor_slug": "kailera",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07398417",
"publication_url": "https://clinicaltrials.gov/study/NCT07398417",
"title": "A Double-Blind, Placebo-Controlled, Randomized Withdrawal Study to Assess the Efficacy and Safety of AXS-14 in the Management of Fibromyalgia",
"has_exemption": false,
"start_date": "2026-01-14",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Axsome Therapeutics, Inc.",
"sponsor_slug": "axsome-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07183319",
"publication_url": "https://clinicaltrials.gov/study/NCT07183319",
"title": "Circulating Tumor DNA Response Adapted Treatment De-escalation Metastatic Urothelial Carcinoma (CT-READ)",
"has_exemption": false,
"start_date": "2026-01-19",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Oklahoma",
"sponsor_slug": "university-of-oklahoma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07258407",
"publication_url": "https://clinicaltrials.gov/study/NCT07258407",
"title": "A Phase 1/2 Dose Escalation Trial With Administration Schedule Exploration Evaluating Single Agent TD001, a PSMA-Targeted Antibody-Drug Conjugate, in Patients With PSMA-Expressing Metastatic Castration-Resistant Prostate Cancer",
"has_exemption": false,
"start_date": "2026-01-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "T.O.A.D. Oncology SA",
"sponsor_slug": "toad-oncology-sa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04901741",
"publication_url": "https://clinicaltrials.gov/study/NCT04901741",
"title": "An Open-label Phase 2 Study of Olaptesed Pegol (NOX-A12) Combined With Pembrolizumab and Nanoliposomal Irinotecan/5-FU/Leucovorin or Gemcitabine/Nab-paclitaxel in Microsatellite-stable Metastatic Pancreatic Cancer Patients",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "TME Pharma AG",
"sponsor_slug": "tme-pharma-ag",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07322003",
"publication_url": "https://clinicaltrials.gov/study/NCT07322003",
"title": "A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Pridopidine in Participants With Amyotrophic Lateral Sclerosis",
"has_exemption": false,
"start_date": "2026-02-01",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Prilenia",
"sponsor_slug": "prilenia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07321886",
"publication_url": "https://clinicaltrials.gov/study/NCT07321886",
"title": "A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Once Weekly Eloralintide in Adult Participants With Obesity or Overweight, Without Type 2 Diabetes",
"has_exemption": false,
"start_date": "2026-02-06",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07353931",
"publication_url": "https://clinicaltrials.gov/study/NCT07353931",
"title": "A Master Protocol for Phase 3 Randomized, Double-Blind, Placebo-Controlled Studies to Investigate the Efficacy and Safety of Once Weekly Eloralintide in Adult Participants With Osteoarthritis Knee Pain, and Obesity or Overweight (ENLIGHTEN-4)",
"has_exemption": false,
"start_date": "2026-02-09",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07369011",
"publication_url": "https://clinicaltrials.gov/study/NCT07369011",
"title": "A Master Protocol for Phase 3 Randomized, Double-Blind, Placebo-Controlled Studies to Investigate the Efficacy and Safety of Once Weekly Eloralintide in Adult Participants With Moderate to Severe Obstructive Sleep Apnea, and Obesity or Overweight",
"has_exemption": false,
"start_date": "2026-02-10",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07420283",
"publication_url": "https://clinicaltrials.gov/study/NCT07420283",
"title": "A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study With a Separate Open-label Cohort to Evaluate the Efficacy and Safety of Brenipatide as Adjunctive Treatment to Transmucosal Buprenorphine With or Without Naloxone in Early Recovery of Participants With Opioid Use Disorder (RENEW-Op-1)",
"has_exemption": false,
"start_date": "2026-02-13",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06842498",
"publication_url": "https://clinicaltrials.gov/study/NCT06842498",
"title": "A Phase 2 Dose Optimization Trial Evaluating a CD46-Targeted Antibody-Drug Conjugate (FG-3246) in Patients With Metastatic Castration-Resistant Prostate Cancer",
"has_exemption": false,
"start_date": "2026-02-22",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kyntra Bio",
"sponsor_slug": "kyntra-bio",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07287150",
"publication_url": "https://clinicaltrials.gov/study/NCT07287150",
"title": "A Phase II, Randomized, Multicenter, Open-Label Study Evaluating the Efficacy and Safety of the Combination of Inavolisib Plus Enzalutamide Versus Physician's Choice of ARPI or Docetaxel in Patients With Metastatic Castration-Resistant Prostate Cancer",
"has_exemption": false,
"start_date": "2026-03-11",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07477457",
"publication_url": "https://clinicaltrials.gov/study/NCT07477457",
"title": "OstEvo - Osteosarcoma Evolves",
"has_exemption": false,
"start_date": "2026-03-11",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07542470",
"publication_url": "https://clinicaltrials.gov/study/NCT07542470",
"title": "Assessing Outcomes in Spinal Surgery Patients Who Receive Iceless Cryopneumatic Therapy Using the NICE1 Device as Compared to Standard of Care",
"has_exemption": false,
"start_date": "2026-03-15",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sarasota Memorial Health Care System",
"sponsor_slug": "sarasota-memorial-health-care-system",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07736937",
"publication_url": "https://clinicaltrials.gov/study/NCT07736937",
"title": "A Multicenter, Phase Ib/II Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Clinical Activity of TUB-040, in Combination With Standard Ovarian Cancer Drugs in Patients With High-grade Epithelial Serous or Endometrioid Epithelial Ovarian Cancer OC)",
"has_exemption": false,
"start_date": "2026-03-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Gilead Sciences",
"sponsor_slug": "gilead-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07339358",
"publication_url": "https://clinicaltrials.gov/study/NCT07339358",
"title": "Safety & Performance of the World Medica World Diverter Embolization Device",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "World Medica USA, LLC",
"sponsor_slug": "world-medica-usa-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07401290",
"publication_url": "https://clinicaltrials.gov/study/NCT07401290",
"title": "The Safety and Efficacy of Direct SLT in Pseudoexfoliation Glaucoma",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vance Thompson Vision",
"sponsor_slug": "vance-thompson-vision",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07389031",
"publication_url": "https://clinicaltrials.gov/study/NCT07389031",
"title": "Maralixibat for the trEatment of inTrAhePatic cHOlestasis of pRegnancy (METAPHOR)",
"has_exemption": false,
"start_date": "2026-04-01",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Imperial College London",
"sponsor_slug": "imperial-college-london",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07843849",
"publication_url": "https://clinicaltrials.gov/study/NCT07843849",
"title": "Corticosteroid for Diabetic Macular Edema (DME) Study",
"has_exemption": false,
"start_date": "2026-04-07",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt University Medical Center",
"sponsor_slug": "vanderbilt-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07432659",
"publication_url": "https://clinicaltrials.gov/study/NCT07432659",
"title": "Add-On Efficacy of Home-Based Transcutaneous Tibial Nerve Stimulation Via the ZIDA Control Sock in Adults With Overactive Bladder on Preexisting Stable Pharmacotherapy",
"has_exemption": false,
"start_date": "2026-04-17",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University of South Carolina",
"sponsor_slug": "medical-university-of-south-carolina",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07414745",
"publication_url": "https://clinicaltrials.gov/study/NCT07414745",
"title": "MDT-0123 Clinical Trial Targeting Patients Who Require Lumbar Vertebral Fusion in Japan",
"has_exemption": false,
"start_date": "2026-04-24",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medtronic Spinal and Biologics",
"sponsor_slug": "medtronic-spinal-and-biologics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07614321",
"publication_url": "https://clinicaltrials.gov/study/NCT07614321",
"title": "Is Silodosin Effective for Treating Lower Urinary Tract Symptoms in Female Patients With Multiple Sclerosis? A Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Atlantic Health System",
"sponsor_slug": "atlantic-health-system",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07602699",
"publication_url": "https://clinicaltrials.gov/study/NCT07602699",
"title": "A Multi-Site Trial of Tirzepatide for Smoking Cessation",
"has_exemption": false,
"start_date": "2026-06-05",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Southern California",
"sponsor_slug": "university-of-southern-california",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07734415",
"publication_url": "https://clinicaltrials.gov/study/NCT07734415",
"title": "A Long-term Extension Study to Evaluate the Safety and Efficacy of Subcutaneous IMG-007 in Participants of a Previous IMG-007 Moderate-To-Severe Atopic Dermatitis Clinical Trial",
"has_exemption": false,
"start_date": "2026-06-05",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Inmagene LLC",
"sponsor_slug": "inmagene-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07568145",
"publication_url": "https://clinicaltrials.gov/study/NCT07568145",
"title": "PREVENT Study: Promoting Resilience Via Early Neurostimulation After Trauma",
"has_exemption": false,
"start_date": "2026-06-18",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07536269",
"publication_url": "https://clinicaltrials.gov/study/NCT07536269",
"title": "A Phase 2, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Crinecerfont in Pediatric Participants 3 Months to <4 Years of Age With Classic Congenital Adrenal Hyperplasia",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Neurocrine Switzerland GmbH",
"sponsor_slug": "neurocrine-switzerland-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07663422",
"publication_url": "https://clinicaltrials.gov/study/NCT07663422",
"title": "GU-228: Mycophenolate Mofetil in Combination With Prednisone as First-line Treatment of Immune Related Hepatitis Resulting From Checkpoint Inhibitor Therapy",
"has_exemption": false,
"start_date": "2026-07-23",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Fox Chase Cancer Center",
"sponsor_slug": "fox-chase-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227779",
"publication_url": "https://clinicaltrials.gov/study/NCT07227779",
"title": "A PHASE 2 NOVEL ANTIMICROBIAL COMBINATION THERAPY TO TREAT TUBERCULOUS MENINGITIS",
"has_exemption": false,
"start_date": "2026-07-28",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "David Boulware",
"sponsor_slug": "david-boulware",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06605651",
"publication_url": "https://clinicaltrials.gov/study/NCT06605651",
"title": "A Phase II Proof of Concept Multicenter, Randomized, Double-Blind Study to Assess the Safety and Efficacy of Phage Therapy in Patients With Hip or Knee Prosthetic Joint Infection Due to Staphylococcus Aureus Treated by DAIR",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Phagenix",
"sponsor_slug": "phagenix",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07431307",
"publication_url": "https://clinicaltrials.gov/study/NCT07431307",
"title": "A Two-part Phase IIb Randomized, Multicenter, Open-label Comparative Study to Firstly Evaluate the Safety and Efficacy Trial of BV100 in Combination With Low Dose Polymyxin B Plus Ceftazidime/Avibactam, or Plus Cefiderocol Versus Best Available Therapy in Patients With Hospital-acquired Bacterial Pneumonia, Ventilator-associated Bacterial Pneumonia and Bloodstream Infection, Suspected or Confirmed to be Due to Carbapenem-resistant Acinetobacter Baumannii Calcoaceticus Complex (CRABC), and Secondly to Evaluate the Pharmacokinetics of BV100 in Combination With Low Dose Polymyxin B Plus Cefideroc",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "BioVersys AG",
"sponsor_slug": "bioversys-ag",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07723248",
"publication_url": "https://clinicaltrials.gov/study/NCT07723248",
"title": "A Phase 3, Randomized, Open-Label Study of Rinzimetostat (ORIC-944) in Combination With Darolutamide Compared With ARPI or Docetaxel in Patients With Metastatic Castration Resistant Prostate Cancer Previously Treated With Abiraterone Acetate (Himalayas-1)",
"has_exemption": false,
"start_date": "2026-08-03",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ORIC Pharmaceuticals",
"sponsor_slug": "oric-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07752979",
"publication_url": "https://clinicaltrials.gov/study/NCT07752979",
"title": "A Phase 2 Dose-Finding Study to Assess the Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities",
"has_exemption": false,
"start_date": "2026-08-04",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06137365",
"publication_url": "https://clinicaltrials.gov/study/NCT06137365",
"title": "A Randomized, Placebo-Controlled Clinical Trial of Once Daily Oral Cannabis for Weight Loss in Obese Individuals",
"has_exemption": false,
"start_date": "2026-08-05",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Joshua A. Lile, Ph.D.",
"sponsor_slug": "joshua-a-lile-phd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06938412",
"publication_url": "https://clinicaltrials.gov/study/NCT06938412",
"title": "Exercise Activity Intervention With Sensor-Based Engagement in Patients With Atrial Fibrillation (EASE-AF)",
"has_exemption": false,
"start_date": "2026-08-11",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Icahn School of Medicine at Mount Sinai",
"sponsor_slug": "icahn-school-of-medicine-at-mount-sinai",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07585968",
"publication_url": "https://clinicaltrials.gov/study/NCT07585968",
"title": "Safety and Effectiveness of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia",
"has_exemption": false,
"start_date": "2026-08-17",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medtronic Cardiac Ablation Solutions",
"sponsor_slug": "medtronic-cardiac-ablation-solutions",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07143448",
"publication_url": "https://clinicaltrials.gov/study/NCT07143448",
"title": "Phase 1b/2, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study Assessing the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of HS235 Added to Background Treatment in Adults With PAH",
"has_exemption": false,
"start_date": "2026-08-19",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "35Pharma Inc",
"sponsor_slug": "35pharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07695558",
"publication_url": "https://clinicaltrials.gov/study/NCT07695558",
"title": "Post Market Study of the Flexagon Only System and Flexagon Plus OTOLoc for Creation of Side-to-Side Duodeno-Ileal Diversion & Flexagon Plus OTOLoc Self Forming Magnet (SFM) System for Creation of Side-to-Side Jejunum-Jejunum and Ileal-Ileal Anastomoses",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "GI Windows, Inc.",
"sponsor_slug": "gi-windows-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06899178",
"publication_url": "https://clinicaltrials.gov/study/NCT06899178",
"title": "A Phase 2, Double Blind, Randomized, Placebo-controlled Crossover Trial to Evaluate the Efficacy and Safety of Atomoxetine in Adults With Melanocortin Obesity Syndrome",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Icahn School of Medicine at Mount Sinai",
"sponsor_slug": "icahn-school-of-medicine-at-mount-sinai",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07465757",
"publication_url": "https://clinicaltrials.gov/study/NCT07465757",
"title": "A Phase 2 Study of Alisertib in Combination With Paclitaxel in Patients With Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2026-09-17",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Puma Biotechnology, Inc.",
"sponsor_slug": "puma-biotechnology-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07868536",
"publication_url": "https://clinicaltrials.gov/study/NCT07868536",
"title": "A Pilot Randomized, Double-Blind, Placebo-Controlled Trial of Single-Dose Oral 17β-Estradiol Administered Within 120 Hours of Sexual Assault to Evaluate Feasibility, Acceptability, and Preliminary Effects on Chronic Musculoskeletal Pain and PTSD Over the Following Three Months",
"has_exemption": false,
"start_date": "2026-09-28",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of North Carolina, Chapel Hill",
"sponsor_slug": "university-of-north-carolina-chapel-hill",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07304102",
"publication_url": "https://clinicaltrials.gov/study/NCT07304102",
"title": "Assessment of GORE® EXCLUDER® IBE Plus Stent Graft Performance in Patients Undergoing Endovascular Iliac Revascularization",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "W.L.Gore & Associates",
"sponsor_slug": "wlgore-associates",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07727980",
"publication_url": "https://clinicaltrials.gov/study/NCT07727980",
"title": "Tissue Preservation in Immediate 1C Implants Using an Anatomical Prefabricated Healing Abutment",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Illinois at Chicago",
"sponsor_slug": "university-of-illinois-at-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07807163",
"publication_url": "https://clinicaltrials.gov/study/NCT07807163",
"title": "A Multicenter, Open-label, Randomized Phase 2 Study Evaluating Continuous Weekly Dosing of Ficerafusp Alfa (BCA101) in Combination With Pembrolizumab Versus an Alternative Ficerafusp Alfa Dosing Regimen for First-Line Treatment of Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Bicara Therapeutics",
"sponsor_slug": "bicara-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07824167",
"publication_url": "https://clinicaltrials.gov/study/NCT07824167",
"title": "Longitudinal Serum and Mucosal RSV Antibodies Following Clesrovimab (Enflonsia™, Merck) Administration in Infants During Their First Respiratory Season or [The EMBRACE Study: Enflonsia™ Monoclonal in Babies - RSV Antibody Concentration Evaluation]",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06682767",
"publication_url": "https://clinicaltrials.gov/study/NCT06682767",
"title": "A Nutritional and Pharmacological Intervention for Body, Brain, and Longevity Effects (NIBBLE) - A Randomized Open-label Intervention of the Fasting-mimicking Diet (FMD) and Rapamycin (NIBBLE)",
"has_exemption": false,
"start_date": "2026-11-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Cedars-Sinai Medical Center",
"sponsor_slug": "cedars-sinai-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07247006",
"publication_url": "https://clinicaltrials.gov/study/NCT07247006",
"title": "Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression",
"has_exemption": false,
"start_date": "2026-12-31",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Rochester",
"sponsor_slug": "university-of-rochester",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07825844",
"publication_url": "https://clinicaltrials.gov/study/NCT07825844",
"title": "Translating Science Into Tools for Return of Facial Function",
"has_exemption": false,
"start_date": "2026-12-31",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Medical Branch, Galveston",
"sponsor_slug": "the-university-of-texas-medical-branch-galveston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05402384",
"publication_url": "https://clinicaltrials.gov/study/NCT05402384",
"title": "Evaluation of Efficacy and Safety of D-galactose Supplementation in SLC35A2-CDG, a Disorder of Hypogalactosylation",
"has_exemption": false,
"start_date": "2027-01-31",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eva Morava-Kozicz",
"sponsor_slug": "eva-morava-kozicz",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07246629",
"publication_url": "https://clinicaltrials.gov/study/NCT07246629",
"title": "Prophylactic Use of Intrathecal Calcium Channel Antagonist Through Lumbar Drain in Patients With Subarachnoid Hemorrhage Due to Aneurysmal Rupture",
"has_exemption": false,
"start_date": "2027-01-31",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07831447",
"publication_url": "https://clinicaltrials.gov/study/NCT07831447",
"title": "A Randomized, Participant-Blinded, Sham-Controlled Study of Noninvasive Hypersound Radiofrequency Neuromodulation for Chronic Neuropathic and Radicular Pain",
"has_exemption": false,
"start_date": "2027-06-30",
"completion_date": "2028-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hypersound Medical Inc",
"sponsor_slug": "hypersound-medical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03947450",
"publication_url": "https://clinicaltrials.gov/study/NCT03947450",
"title": "Autologous Volar Fibroblast Injection Into the Stump Site of Amputees",
"has_exemption": false,
"start_date": "2019-09-05",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03772028",
"publication_url": "https://clinicaltrials.gov/study/NCT03772028",
"title": "Phase III Randomized Clinical Trial for Stage III Epithelial Ovarian Cancer Randomizing Between Primary Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy",
"has_exemption": false,
"start_date": "2020-01-01",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "The Netherlands Cancer Institute",
"sponsor_slug": "the-netherlands-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04752137",
"publication_url": "https://clinicaltrials.gov/study/NCT04752137",
"title": "Evaluation of Intraoperative Tumor Margin Identification With Fluorescent Dye Imaging",
"has_exemption": false,
"start_date": "2022-05-25",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05764642",
"publication_url": "https://clinicaltrials.gov/study/NCT05764642",
"title": "Renal Microvessel Imaging for Characterization of Chronic Kidney Disease",
"has_exemption": false,
"start_date": "2023-08-09",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06062875",
"publication_url": "https://clinicaltrials.gov/study/NCT06062875",
"title": "Effects of TNF Blockade on Human BPH/LUTS",
"has_exemption": false,
"start_date": "2024-01-24",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Endeavor Health",
"sponsor_slug": "endeavor-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06073665",
"publication_url": "https://clinicaltrials.gov/study/NCT06073665",
"title": "Levothyroxine Dosing in Older Individuals",
"has_exemption": false,
"start_date": "2024-01-31",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06350045",
"publication_url": "https://clinicaltrials.gov/study/NCT06350045",
"title": "Renal Puncture Above the Eleventh Rib (High Supracostal Approach) Versus Subcostal Puncture in Percutaneous Nephrolithotomy for Treatment of Renal Stones in Adults: A Prospective Randomized Trial",
"has_exemption": false,
"start_date": "2024-03-01",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Assiut University",
"sponsor_slug": "assiut-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06867549",
"publication_url": "https://clinicaltrials.gov/study/NCT06867549",
"title": "Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) Stage II",
"has_exemption": false,
"start_date": "2025-03-04",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07212062",
"publication_url": "https://clinicaltrials.gov/study/NCT07212062",
"title": "A Phase II, Randomized, Double-Blind, Placebo Controlled Study to Evaluate the Sfatey and Tolerability of X/T+X-EC vs. Placebo in Participants With Alzheimer's Disease Currently Treated With Lecanemab.",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Neurology Office of South Florida",
"sponsor_slug": "neurology-office-of-south-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06961084",
"publication_url": "https://clinicaltrials.gov/study/NCT06961084",
"title": "Comparison of I-124 PET/CT to I-123 Whole Body Imaging for the Diagnosis of Thyroid",
"has_exemption": false,
"start_date": "2025-12-04",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Thomas Hope",
"sponsor_slug": "thomas-hope",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06853223",
"publication_url": "https://clinicaltrials.gov/study/NCT06853223",
"title": "A Randomized Trial of CCR5 Inhibition as a Complement to Lung Transplant Induction Immunosuppression",
"has_exemption": false,
"start_date": "2025-12-07",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06150599",
"publication_url": "https://clinicaltrials.gov/study/NCT06150599",
"title": "Sacral Neuromodulation for the Treatment of Chronic Pelvic Pain",
"has_exemption": false,
"start_date": "2026-01-27",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Corewell Health East",
"sponsor_slug": "corewell-health-east",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06822010",
"publication_url": "https://clinicaltrials.gov/study/NCT06822010",
"title": "A Phase II Trial of SeqUential GeMcitabine and MITomycin Treatment for Favorable High-Risk Upper Urinary Tract Urothelial Carcinoma (SUMMIT)",
"has_exemption": false,
"start_date": "2026-03-06",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Rutgers, The State University of New Jersey",
"sponsor_slug": "rutgers-the-state-university-of-new-jersey",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07339163",
"publication_url": "https://clinicaltrials.gov/study/NCT07339163",
"title": "Efficacy of Booster Injection With Gardasil-9 Vaccine on Intersurgical Interval (ISI) for Adults With Recurrent Respiratory Papillomatosis (RRP)",
"has_exemption": false,
"start_date": "2026-04-01",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Ohio State University",
"sponsor_slug": "ohio-state-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07553442",
"publication_url": "https://clinicaltrials.gov/study/NCT07553442",
"title": "A Phase 2, Randomized, Double-blind, Placebo-controlled, Single Dose Study of the Efficacy, Pharmacodynamics, and Safety of ALN-AGT01 RVR in Adult Patients With Mild to Moderate Hypertension Pretreated With Zilebesiran",
"has_exemption": false,
"start_date": "2026-04-27",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Alnylam Pharmaceuticals",
"sponsor_slug": "alnylam-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07492134",
"publication_url": "https://clinicaltrials.gov/study/NCT07492134",
"title": "Comparing Placebo Versus Antibiotics for Acute Uncomplicated Diverticulitis",
"has_exemption": false,
"start_date": "2026-07-07",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Vanderbilt University Medical Center",
"sponsor_slug": "vanderbilt-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07714369",
"publication_url": "https://clinicaltrials.gov/study/NCT07714369",
"title": "Zavegepant Intranasal Spray for the Acute Treatment of Episodic Cluster Headache: A Prospective, Open-Label, Single-Arm, Interventional Pilot Study",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07285473",
"publication_url": "https://clinicaltrials.gov/study/NCT07285473",
"title": "Low-dose Naltrexone (LDN) for the Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Dose-Finding",
"has_exemption": false,
"start_date": "2026-11-01",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05509842",
"publication_url": "https://clinicaltrials.gov/study/NCT05509842",
"title": "High-dose Accelerated Theta Burst Stimulation to Restore PD-induced Motor Network Dysconnectivity",
"has_exemption": false,
"start_date": "2027-09-01",
"completion_date": "2028-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan",
"sponsor_slug": "university-of-michigan",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04568616",
"publication_url": "https://clinicaltrials.gov/study/NCT04568616",
"title": "Phase II Study of Neoadjuvant ArOMatase Inhibitor Therapy for ER+ Breast Cancer (NAOMI)",
"has_exemption": false,
"start_date": "2021-08-13",
"completion_date": "2028-04-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Dartmouth-Hitchcock Medical Center",
"sponsor_slug": "dartmouth-hitchcock-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06833008",
"publication_url": "https://clinicaltrials.gov/study/NCT06833008",
"title": "An Open-label, Phase I/II First-in-human, Dose Escalation and Confirmation Study to Evaluate the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic and Anti-tumour Activity of IPN01195 as Single Agent in Adult Participants With Advanced Solid Tumours",
"has_exemption": false,
"start_date": "2025-03-14",
"completion_date": "2028-04-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Ipsen",
"sponsor_slug": "ipsen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07851038",
"publication_url": "https://clinicaltrials.gov/study/NCT07851038",
"title": "Bayesian-Optimized Dose-Finding of ATTN201 Focused Ultrasound for Behavioral Health",
"has_exemption": false,
"start_date": "2026-10-05",
"completion_date": "2028-04-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Attune Neurosciences Inc",
"sponsor_slug": "attune-neurosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06919965",
"publication_url": "https://clinicaltrials.gov/study/NCT06919965",
"title": "A Phase 3, Randomized, Open-label, Multicenter Study Evaluating the Efficacy and Safety of TAR-210 Erdafitinib Intravesical Delivery System Versus Investigator's Choice of Intravesical Chemotherapy in Participants With High-risk Non-muscle-invasive Bladder Cancer With Susceptible FGFR Alterations Who Had Received Intravesical Bacillus Calmette-Guérin (BCG)",
"has_exemption": false,
"start_date": "2025-09-10",
"completion_date": "2028-04-06",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05694871",
"publication_url": "https://clinicaltrials.gov/study/NCT05694871",
"title": "Official Title A Randomized Phase 2 Trial With a Safety Lead-In to Evaluate Palbociclib Versus Palbociclib and Cemiplimab for the Treatment of Advanced Dedifferentiated Liposarcoma",
"has_exemption": false,
"start_date": "2023-06-07",
"completion_date": "2028-04-07",
"has_results": false,
"results_due": false,
"sponsor_name": "Alliance for Clinical Trials in Oncology",
"sponsor_slug": "alliance-for-clinical-trials-in-oncology",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07149207",
"publication_url": "https://clinicaltrials.gov/study/NCT07149207",
"title": "Intraoperative Molecular Imaging Using ICG for Head and Neck Tumors",
"has_exemption": false,
"start_date": "2026-05-04",
"completion_date": "2028-04-07",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University of South Carolina",
"sponsor_slug": "medical-university-of-south-carolina",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07202247",
"publication_url": "https://clinicaltrials.gov/study/NCT07202247",
"title": "A Phase II Randomized Study of Interventions for Metabolic Protection Against Cardiometabolic Toxicity During Androgen Deprivation Therapy (IMPACT-ADT)",
"has_exemption": false,
"start_date": "2025-11-05",
"completion_date": "2028-04-09",
"has_results": false,
"results_due": false,
"sponsor_name": "City of Hope Medical Center",
"sponsor_slug": "city-of-hope-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04789486",
"publication_url": "https://clinicaltrials.gov/study/NCT04789486",
"title": "Nano-SMART: An Adaptive Phase I-II Trial of AGuIX Gadolinium-based Nanoparticles With Stereotactic Magnetic Resonance-guided Adaptive Radiation Therapy for Centrally Located Lung Tumors and Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma",
"has_exemption": false,
"start_date": "2021-05-27",
"completion_date": "2028-04-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Dana-Farber Cancer Institute",
"sponsor_slug": "dana-farber-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06784726",
"publication_url": "https://clinicaltrials.gov/study/NCT06784726",
"title": "Odronextamab for Relapsed/Refractory Large B-Cell Lymphomas Before Definitive Lymphoma-Directed Therapies",
"has_exemption": false,
"start_date": "2025-09-04",
"completion_date": "2028-04-10",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Washington",
"sponsor_slug": "university-of-washington",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07537153",
"publication_url": "https://clinicaltrials.gov/study/NCT07537153",
"title": "Genicular Artery Embolization for Patients With Mild-To-Moderate Knee Osteoarthritis",
"has_exemption": false,
"start_date": "2026-07-10",
"completion_date": "2028-04-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07231952",
"publication_url": "https://clinicaltrials.gov/study/NCT07231952",
"title": "A Phase II Study of Time-limited Combination of Pirtobrutinib, Venetoclax, and Rituximab in Treatment Naïve Patients With Waldenström's Macroglobulinemia (WM) / Lymphoplasmacytic Lymphoma (LPL) (PRoVen)",
"has_exemption": false,
"start_date": "2025-11-11",
"completion_date": "2028-04-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06260683",
"publication_url": "https://clinicaltrials.gov/study/NCT06260683",
"title": "A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-Cigarettes on Smoking Behavior",
"has_exemption": false,
"start_date": "2024-04-10",
"completion_date": "2028-04-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Ohio State University Comprehensive Cancer Center",
"sponsor_slug": "ohio-state-university-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06668181",
"publication_url": "https://clinicaltrials.gov/study/NCT06668181",
"title": "Open-Label, Single-Arm Trial to Evaluate the Pharmacokinetics and Safety of Bimekizumab in Pediatric Study Participants From 2 to Less Than 18 Years of Age With Active Juvenile Idiopathic Arthritis Subtypes Enthesitis-Related Arthritis (Including Juvenile-Onset Ankylosing Spondylitis) and Juvenile Psoriatic Arthritis",
"has_exemption": false,
"start_date": "2025-03-11",
"completion_date": "2028-04-12",
"has_results": false,
"results_due": false,
"sponsor_name": "UCB Biopharma SRL",
"sponsor_slug": "ucb-biopharma-srl",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07149857",
"publication_url": "https://clinicaltrials.gov/study/NCT07149857",
"title": "A Phase 2 Multicohort Trial to Further Characterize the Efficacy and Safety of Ciltacabtagene Autoleucel",
"has_exemption": false,
"start_date": "2025-10-03",
"completion_date": "2028-04-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04573478",
"publication_url": "https://clinicaltrials.gov/study/NCT04573478",
"title": "A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Atrasentan in Patients With IgA Nephropathy at Risk of Progressive Loss of Renal Function",
"has_exemption": false,
"start_date": "2020-12-11",
"completion_date": "2028-04-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06533644",
"publication_url": "https://clinicaltrials.gov/study/NCT06533644",
"title": "A Phase 2a Multicenter, Dose-Escalation and Dose Optimization Study of SYNC-T Therapy SV-102 for Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC)",
"has_exemption": false,
"start_date": "2025-05-29",
"completion_date": "2028-04-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Syncromune, Inc.",
"sponsor_slug": "syncromune-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07023432",
"publication_url": "https://clinicaltrials.gov/study/NCT07023432",
"title": "Belzutifan's Role in Active Surveillance Versus Treatment for Indolentmetastatic Clear Cell Renal Ccell Carcinoma (BRAVE-RCC)",
"has_exemption": false,
"start_date": "2025-11-17",
"completion_date": "2028-04-14",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04515836",
"publication_url": "https://clinicaltrials.gov/study/NCT04515836",
"title": "Phase II Trial of Olaparib in Homologous Recombination Deficient (HRD) Malignant Mesothelioma",
"has_exemption": false,
"start_date": "2021-02-19",
"completion_date": "2028-04-15",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04988386",
"publication_url": "https://clinicaltrials.gov/study/NCT04988386",
"title": "An Open-Label Extension and Safety Monitoring Study of Acoramidis (AG10) in Participants With Symptomatic Transthyretin Amyloid Cardiomyopathy Who Completed the Phase 3 ATTRibute-CM Trial (AG10-301)",
"has_exemption": false,
"start_date": "2021-10-27",
"completion_date": "2028-04-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Eidos Therapeutics, a BridgeBio company",
"sponsor_slug": "eidos-therapeutics-a-bridgebio-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07156578",
"publication_url": "https://clinicaltrials.gov/study/NCT07156578",
"title": "A Long-Term, Open-Label Extension Study of Bivamelagon in Participants With Hypothalamic Obesity (HO)",
"has_exemption": false,
"start_date": "2025-11-10",
"completion_date": "2028-04-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Rhythm Pharmaceuticals, Inc.",
"sponsor_slug": "rhythm-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227857",
"publication_url": "https://clinicaltrials.gov/study/NCT07227857",
"title": "A Phase Ib/II First-in-human, Multicentre, Open-label, Multiple Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effect of Intrathecal S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy",
"has_exemption": false,
"start_date": "2025-11-24",
"completion_date": "2028-04-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Institut de Recherches Internationales Servier",
"sponsor_slug": "institut-de-recherches-internationales-servier",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07332091",
"publication_url": "https://clinicaltrials.gov/study/NCT07332091",
"title": "A Phase 2, Multicenter, Randomized, Placebo-controlled, Double-blind Study of the Efficacy and Safety of Vamifeport in Adult Subjects With HFE-related Hereditary Hemochromatosis (FERROCLEAR Study)",
"has_exemption": false,
"start_date": "2026-01-22",
"completion_date": "2028-04-15",
"has_results": false,
"results_due": false,
"sponsor_name": "CSL Behring",
"sponsor_slug": "csl-behring",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07871552",
"publication_url": "https://clinicaltrials.gov/study/NCT07871552",
"title": "A Pilot, Randomized, Open-Label Trial of the Effects of Switch to Doravirine/Islatravir vs. Continued Antiretroviral Therapy on Biomarkers of Aging Among Virologically Suppressed People With HIV",
"has_exemption": false,
"start_date": "2026-10-30",
"completion_date": "2028-04-15",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03153449",
"publication_url": "https://clinicaltrials.gov/study/NCT03153449",
"title": "Multi-Center Clinical Evaluation of the ATTUNE Revision System in Complex Primary Total Knee Arthroplasty",
"has_exemption": false,
"start_date": "2017-09-19",
"completion_date": "2028-04-17",
"has_results": false,
"results_due": false,
"sponsor_name": "DePuy Orthopaedics",
"sponsor_slug": "depuy-orthopaedics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05859568",
"publication_url": "https://clinicaltrials.gov/study/NCT05859568",
"title": "Baseline Performance and Fitting Parameters for Sonova Products",
"has_exemption": false,
"start_date": "2023-04-17",
"completion_date": "2028-04-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Advanced Bionics",
"sponsor_slug": "advanced-bionics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06973187",
"publication_url": "https://clinicaltrials.gov/study/NCT06973187",
"title": "A Phase 3, Open-Label, Randomized Study to Evaluate the Safety and Efficacy of BGB-16673 Compared to Pirtobrutinib in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma",
"has_exemption": false,
"start_date": "2025-09-04",
"completion_date": "2028-04-17",
"has_results": false,
"results_due": false,
"sponsor_name": "BeOne Medicines",
"sponsor_slug": "beone-medicines",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07130903",
"publication_url": "https://clinicaltrials.gov/study/NCT07130903",
"title": "A Phase 2 Study of Amplitude-Modulated Radiofrequency Electromagnetic Fields (AM RF EMF) in Combination With Fruquintinib in Refractory Metastatic Colorectal Cancer",
"has_exemption": false,
"start_date": "2025-09-10",
"completion_date": "2028-04-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Barbara Ann Karmanos Cancer Institute",
"sponsor_slug": "barbara-ann-karmanos-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07845682",
"publication_url": "https://clinicaltrials.gov/study/NCT07845682",
"title": "A Prospective, Multicenter, Single Arm With Performance Goal Study to Evaluate Safety and Effectiveness of Dual Energy THERMOCOOL SMARTTOUCH™ SF Catheter With the TRUPULSE™ Generator in Persistent Atrial Fibrillation (PsAF)",
"has_exemption": false,
"start_date": "2026-09-24",
"completion_date": "2028-04-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Biosense Webster, Inc.",
"sponsor_slug": "biosense-webster-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06065748",
"publication_url": "https://clinicaltrials.gov/study/NCT06065748",
"title": "A Phase III Randomized, Open-Label Study Evaluating Efficacy and Safety of Giredestrant Compared With Fulvestrant, Both Combined With a CDK4/6 Inhibitor, in Patients With Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer With Resistance to Prior Adjuvant Endocrine Therapy",
"has_exemption": false,
"start_date": "2023-12-11",
"completion_date": "2028-04-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06907615",
"publication_url": "https://clinicaltrials.gov/study/NCT06907615",
"title": "An Open-label, Multi-center, Global Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX43 (Anti-PD-L1 ADC) in Subjects With Advanced Non-small Cell Lung Cancer (NSCLC)",
"has_exemption": false,
"start_date": "2025-06-09",
"completion_date": "2028-04-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Shanghai Henlius Biotech",
"sponsor_slug": "shanghai-henlius-biotech",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07857330",
"publication_url": "https://clinicaltrials.gov/study/NCT07857330",
"title": "A Study on the Feasibility of a Novel Guidance Method for Leadless Pacemaker Implantation",
"has_exemption": false,
"start_date": "2026-10-20",
"completion_date": "2028-04-20",
"has_results": false,
"results_due": false,
"sponsor_name": "China National Center for Cardiovascular Diseases",
"sponsor_slug": "china-national-center-for-cardiovascular-diseases",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06526793",
"publication_url": "https://clinicaltrials.gov/study/NCT06526793",
"title": "A Modular Phase 2, Single-arm, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of Surovatamig (AZD0486) in Participants With Relapsed or Refractory (R/R) B-cell Non-Hodgkin Lymphoma (SOUNDTRACK-B)",
"has_exemption": false,
"start_date": "2024-11-27",
"completion_date": "2028-04-21",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06788938",
"publication_url": "https://clinicaltrials.gov/study/NCT06788938",
"title": "Tarlatamab in Advanced DLL3-Expressing Tumors Including Neuroendocrine Neoplasms",
"has_exemption": false,
"start_date": "2025-03-21",
"completion_date": "2028-04-24",
"has_results": false,
"results_due": false,
"sponsor_name": "Jonsson Comprehensive Cancer Center",
"sponsor_slug": "jonsson-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06911502",
"publication_url": "https://clinicaltrials.gov/study/NCT06911502",
"title": "A Phase 3, Multicenter, Randomized, Open Label Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) Vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy",
"has_exemption": false,
"start_date": "2025-07-28",
"completion_date": "2028-04-24",
"has_results": false,
"results_due": false,
"sponsor_name": "Celgene",
"sponsor_slug": "celgene",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05536349",
"publication_url": "https://clinicaltrials.gov/study/NCT05536349",
"title": "Time-limited Triplet Combination of Pirtobrutinib, Venetoclax, and Obinutuzumab for Patients With Treatment-naïve Chronic Lymphocytic Leukemia (CLL) or Richter Transformation (RT)",
"has_exemption": false,
"start_date": "2022-12-20",
"completion_date": "2028-04-25",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05939414",
"publication_url": "https://clinicaltrials.gov/study/NCT05939414",
"title": "An International, Prospective, Open-label, Multi-center, Randomized Phase III Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) Versus Observation to Delay Castration or Disease Recurrence in Adult Male Patients With Prostate-specific Membrane Antigen (PSMA) Positive Oligometastatic Prostate Cancer (OMPC)",
"has_exemption": false,
"start_date": "2024-03-12",
"completion_date": "2028-04-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06433011",
"publication_url": "https://clinicaltrials.gov/study/NCT06433011",
"title": "The RAPID - PE Study: RESCUE Advanced Protocol Without ICU Stay and no Lytic Drip - for the Treatment of Pulmonary Embolism",
"has_exemption": false,
"start_date": "2024-10-17",
"completion_date": "2028-04-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Thrombolex, Inc.",
"sponsor_slug": "thrombolex-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04108624",
"publication_url": "https://clinicaltrials.gov/study/NCT04108624",
"title": "A Multimodality Approach to Minimal Residual Disease Detection to Guide Post-Transplant Maintenance Therapy in Multiple Myeloma (MRD2STOP)",
"has_exemption": false,
"start_date": "2019-10-30",
"completion_date": "2028-04-26",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07733765",
"publication_url": "https://clinicaltrials.gov/study/NCT07733765",
"title": "A PHASE 3, RANDOMIZED, DOUBLE BLIND, PLACEBO-CONTROLLED STUDY TO INVESTIGATE THE SAFETY AND EFFICACY OF RITLECITINIB IN ADULT AND ADOLESCENT PARTICIPANTS 12 YEARS OF AGE AND OLDER WITH MODERATE ALOPECIA AREATA",
"has_exemption": false,
"start_date": "2026-07-30",
"completion_date": "2028-04-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05519475",
"publication_url": "https://clinicaltrials.gov/study/NCT05519475",
"title": "A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of siRNA Gene Silencing for the Treatment of Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Participants With Genetic Risk Factors",
"has_exemption": false,
"start_date": "2023-02-09",
"completion_date": "2028-04-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06435429",
"publication_url": "https://clinicaltrials.gov/study/NCT06435429",
"title": "A Phase 3, Randomized, Open-label, Multicenter, Controlled Study to Evaluate the Efficacy and Safety of Zanidatamab in Combination With Physician's Choice Chemotherapy Compared to Trastuzumab in Combination With Physician's Choice Chemotherapy for the Treatment of Participants With Metastatic HER2-positive Breast Cancer Who Have Progressed on, or Are Intolerant to, Previous Trastuzumab Deruxtecan Treatment",
"has_exemption": false,
"start_date": "2024-08-13",
"completion_date": "2028-04-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Jazz Pharmaceuticals",
"sponsor_slug": "jazz-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07430605",
"publication_url": "https://clinicaltrials.gov/study/NCT07430605",
"title": "WearME-Pro Phase II: Remote Use Usability and Longitudinal Validation Study (Patch Form Factor)",
"has_exemption": false,
"start_date": "2026-05-01",
"completion_date": "2028-04-28",
"has_results": false,
"results_due": false,
"sponsor_name": "LASARRUS Clinic and Research Center",
"sponsor_slug": "lasarrus-clinic-and-research-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05974202",
"publication_url": "https://clinicaltrials.gov/study/NCT05974202",
"title": "Augmenting Cognitive-behavioral Therapy With rTMS of the Medial Prefrontal and Anterior Cingulate Cortices for the Treatment of Cocaine Use Disorder",
"has_exemption": false,
"start_date": "2026-08-14",
"completion_date": "2028-04-28",
"has_results": false,
"results_due": false,
"sponsor_name": "New York State Psychiatric Institute",
"sponsor_slug": "new-york-state-psychiatric-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06071767",
"publication_url": "https://clinicaltrials.gov/study/NCT06071767",
"title": "A Phase I/IIa Randomized, Placebo-Controlled Trial of Conserved-Mosaic T-cell Vaccine in a Regimen With Vesatolimod and Broadly Neutralizing Antibodies in Adults Initiated on Suppressive Antiretroviral Therapy During Acute HIV-1",
"has_exemption": false,
"start_date": "2024-04-01",
"completion_date": "2028-04-29",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Allergy and Infectious Diseases (NIAID)",
"sponsor_slug": "national-institute-of-allergy-and-infectious-diseases-niaid",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06358872",
"publication_url": "https://clinicaltrials.gov/study/NCT06358872",
"title": "Azithromycine Pour la Vie Des Enfants au Niger II",
"has_exemption": false,
"start_date": "2024-04-29",
"completion_date": "2028-04-29",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT01760005",
"publication_url": "https://clinicaltrials.gov/study/NCT01760005",
"title": "A Phase II/III Multicenter Randomized, Double-Blind, Placebo-Controlled Platform Trial of Potential Disease Modifying Therapies Utilizing Biomarker, Cognitive, and Clinical Endpoints in Dominantly Inherited Alzheimer's Disease",
"has_exemption": false,
"start_date": "2012-12-31",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02718001",
"publication_url": "https://clinicaltrials.gov/study/NCT02718001",
"title": "Edwards EVOQUE Eos Mitral Valve Replacement: Investigation of Safety and Performance After Mitral Valve Replacement With Transcatheter Device (MISCEND)",
"has_exemption": false,
"start_date": "2015-02-06",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Edwards Lifesciences",
"sponsor_slug": "edwards-lifesciences",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03128996",
"publication_url": "https://clinicaltrials.gov/study/NCT03128996",
"title": "A Phase I/II Trial of Reduced Intensity Conditioning and Familial HLA-Mismatched Bone Marrow Transplantation in Children With Non-Malignant Disorders",
"has_exemption": false,
"start_date": "2017-03-20",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03777267",
"publication_url": "https://clinicaltrials.gov/study/NCT03777267",
"title": "Cereset Research Exploratory Study",
"has_exemption": false,
"start_date": "2019-04-12",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04089059",
"publication_url": "https://clinicaltrials.gov/study/NCT04089059",
"title": "A Prospective, Multi-Center, Open Label, Single Arm Clinical Trial Evaluating the Safety and Efficacy of the Cordella™ Pulmonary Artery Sensor System in NYHA Class III Heart Failure Patients (PROACTIVE- HF Trial)",
"has_exemption": false,
"start_date": "2020-01-10",
"completion_date": "2028-04-30",
"has_results": true,
"results_due": false,
"sponsor_name": "Endotronix, Inc.",
"sponsor_slug": "endotronix-inc",
"status": "reported",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04561401",
"publication_url": "https://clinicaltrials.gov/study/NCT04561401",
"title": "Can Brain Stimulation Enhance Outcomes Associated With Intensive Rehabilitation for Youth With Chronic Pain?",
"has_exemption": false,
"start_date": "2020-10-19",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Calgary",
"sponsor_slug": "university-of-calgary",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04111172",
"publication_url": "https://clinicaltrials.gov/study/NCT04111172",
"title": "A Phase 2A/2B, Dose-Finding and Expansion Study of Ad5.F35-hGCC-PADRE Vaccine in Adults With Gastrointestinal Adenocarcinomas at Risk of Relapse Post Definitive Surgery and Standard Therapy",
"has_exemption": false,
"start_date": "2020-11-10",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Thomas Jefferson University",
"sponsor_slug": "thomas-jefferson-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04725474",
"publication_url": "https://clinicaltrials.gov/study/NCT04725474",
"title": "A Phase 1/2, FIH, Two-part, Open-label Clinical Trial of Intravenous (IV) Administration of CTL-002 Given as Monotherapy and/or in Combination With an Anti-PD-1 Checkpoint Inhibitor in Subjects With Advanced-stage, Relapsed/Refractory Solid Tumors (The \"GDFATHER\"-Trial: GDF-15 Antibody-mediaTed Human Effector Cell Relocation).",
"has_exemption": false,
"start_date": "2020-12-09",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "CatalYm GmbH",
"sponsor_slug": "catalym-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04752722",
"publication_url": "https://clinicaltrials.gov/study/NCT04752722",
"title": "A Phase 1/2 Study of EG-70 as an Intravesical Administration to Patients With BCG Unresponsive Non-Muscle Invasive Bladder Cancer (NMIBC) and High-Risk NMIBC Patients Who Are BCG Naïve or Received Incomplete BCG Treatment",
"has_exemption": false,
"start_date": "2021-04-22",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "enGene, Inc.",
"sponsor_slug": "engene-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04799470",
"publication_url": "https://clinicaltrials.gov/study/NCT04799470",
"title": "Novel DBS Stimulation Patterns for Treatment of Parkinson's Disease - UNMC/Medtronic Collaborative Acute Feasibility Pilot",
"has_exemption": false,
"start_date": "2021-05-10",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Nebraska",
"sponsor_slug": "university-of-nebraska",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04862286",
"publication_url": "https://clinicaltrials.gov/study/NCT04862286",
"title": "OptIMMize-2: A Phase 3 Multicenter, Single-arm, Open-label Extension Study to Assess the Safety, Tolerability, and Efficacy of Risankizumab in Subjects With Moderate to Severe Plaque Psoriasis Who Have Completed Participation in Study M19-977 (OptIMMize-1)",
"has_exemption": false,
"start_date": "2021-07-24",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04899908",
"publication_url": "https://clinicaltrials.gov/study/NCT04899908",
"title": "A Double-blind, Phase II Randomized Study of Brain-directed Stereotactic Radiation With or Without AGuIX Gadolinium-based Nanoparticles in the Management of Brain Metastases at Higher Risk of Local Recurrence With Radiation Alone",
"has_exemption": false,
"start_date": "2021-09-15",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05164172",
"publication_url": "https://clinicaltrials.gov/study/NCT05164172",
"title": "Long-term, Open-label (Dose-blinded), Extension Study of Eptinezumab in Children and Adolescents With Chronic or Episodic Migraine",
"has_exemption": false,
"start_date": "2021-12-01",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lundbeck A/S",
"sponsor_slug": "h-lundbeck-as",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05269394",
"publication_url": "https://clinicaltrials.gov/study/NCT05269394",
"title": "A Phase II/III Multicenter Randomized, Double-Blind, Placebo-Controlled Platform Trial of Potential Disease Modifying Therapies Utilizing Biomarker, Cognitive, and Clinical Endpoints in Dominantly Inherited Alzheimer's Disease",
"has_exemption": false,
"start_date": "2021-12-22",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05356741",
"publication_url": "https://clinicaltrials.gov/study/NCT05356741",
"title": "A Phase 1, Multicenter, Open-Label, First-in-Human Study of the Safety and Pharmacokinetics of VIR-5818 Alone and in Combination With Pembrolizumab in Participants With Locally Advanced or Metastatic HER2-Expressing Cancers",
"has_exemption": false,
"start_date": "2022-04-13",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Vir Biotechnology, Inc.",
"sponsor_slug": "vir-biotechnology-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05321134",
"publication_url": "https://clinicaltrials.gov/study/NCT05321134",
"title": "Evaluation of SINGLE PORT (SP) Robotic Technology in Colorectal Surgery",
"has_exemption": false,
"start_date": "2022-04-28",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Davis",
"sponsor_slug": "university-of-california-davis",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05275192",
"publication_url": "https://clinicaltrials.gov/study/NCT05275192",
"title": "Utilization of a Videoscope to Improve Clinical Outcomes of Periodontal Regeneration. A Pilot Study",
"has_exemption": false,
"start_date": "2022-05-01",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Illinois at Chicago",
"sponsor_slug": "university-of-illinois-at-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05243797",
"publication_url": "https://clinicaltrials.gov/study/NCT05243797",
"title": "Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation - MajesTEC-4",
"has_exemption": false,
"start_date": "2022-09-08",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "European Myeloma Network B.V.",
"sponsor_slug": "european-myeloma-network-bv",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05685433",
"publication_url": "https://clinicaltrials.gov/study/NCT05685433",
"title": "A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)",
"has_exemption": false,
"start_date": "2023-01-26",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Valencia Technologies Corporation",
"sponsor_slug": "valencia-technologies-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04922333",
"publication_url": "https://clinicaltrials.gov/study/NCT04922333",
"title": "Bisphosphonate Use to Mitigate Bone Loss Secondary to Bariatric Surgery",
"has_exemption": false,
"start_date": "2023-03-28",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04919629",
"publication_url": "https://clinicaltrials.gov/study/NCT04919629",
"title": "Randomized Phase 2 Trial of APL-2 With Pembrolizumab vs. APL-2 With Pembrolizumab and Bevacizumab vs. Bevacizumab Alone in Patients With Recurrent Ovarian Cancer and Persistent Malignant Effusion",
"has_exemption": false,
"start_date": "2023-04-27",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Roswell Park Cancer Institute",
"sponsor_slug": "roswell-park-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05681299",
"publication_url": "https://clinicaltrials.gov/study/NCT05681299",
"title": "Effects of Administration of Growth Hormone, Without and With Liraglutide, on AgRP, Energy and Glucose Metabolism in Healthy and GH Deficient Humans",
"has_exemption": false,
"start_date": "2023-05-01",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Columbia University",
"sponsor_slug": "columbia-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05840211",
"publication_url": "https://clinicaltrials.gov/study/NCT05840211",
"title": "A Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients With Hormone Receptor-Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) (HER2 IHC0 or HER2-low [IHC 1+, IHC 2+/ISH-]) Inoperable, Locally Advanced, or Metastatic Breast Cancer and Have Received Endocrine Therapy",
"has_exemption": false,
"start_date": "2023-05-08",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Gilead Sciences",
"sponsor_slug": "gilead-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05313243",
"publication_url": "https://clinicaltrials.gov/study/NCT05313243",
"title": "Phase 2 Study of Pembrolizumab and Brentuximab Vedotin in Subjects With Relapsed/Refractory CD30 Positive T-cell Lymphoma",
"has_exemption": false,
"start_date": "2023-07-10",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05540574",
"publication_url": "https://clinicaltrials.gov/study/NCT05540574",
"title": "Randomized Placebo-Controlled Crossover Trial of Zolpidem for Sleep in Children With Autism",
"has_exemption": false,
"start_date": "2023-08-09",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06020716",
"publication_url": "https://clinicaltrials.gov/study/NCT06020716",
"title": "A Phase 4 Double Blinded Study With Two Different Interventions, Each With Two Arms, to Evaluate the Clinical Efficacy of Antibiotics and the Role of Microbiology, Immunology and Genetics in Children Aged 9-36 Months With Chronic Wet Cough.",
"has_exemption": false,
"start_date": "2023-08-16",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Helse Stavanger HF",
"sponsor_slug": "helse-stavanger-hf",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05878860",
"publication_url": "https://clinicaltrials.gov/study/NCT05878860",
"title": "A Phase 1/2/3, Open-Label, Dose Escalation, Dose Expansion and Randomized, Controlled Study to Evaluate the Safety and Efficacy of ATSN-201 Gene Therapy in Subjects With RS1-Associated X-linked Retinoschisis (LIGHTHOUSE)",
"has_exemption": false,
"start_date": "2023-08-22",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Atsena Therapeutics Inc.",
"sponsor_slug": "atsena-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05692635",
"publication_url": "https://clinicaltrials.gov/study/NCT05692635",
"title": "Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance in Non-Squamous Locally Advanced Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2023-08-30",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05948540",
"publication_url": "https://clinicaltrials.gov/study/NCT05948540",
"title": "A Phase 2, Multi-center, Multi-arm, Randomized, Placebo-controlled, Double-blind, Adaptive Platform Study to Evaluate the Safety, Tolerability, and Efficacy of Potential Pharmacotherapeutic Interventions in Active-Duty Service Members, Veterans, and Non-Veteran Civilians With PTSD",
"has_exemption": false,
"start_date": "2023-11-02",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Global Coalition for Adaptive Research",
"sponsor_slug": "global-coalition-for-adaptive-research",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06162611",
"publication_url": "https://clinicaltrials.gov/study/NCT06162611",
"title": "Generating Evidence to Improve Same-day Etonogestrel (ENG) Implant Insertion for Emergency Contraception",
"has_exemption": false,
"start_date": "2023-11-06",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Lori Gawron",
"sponsor_slug": "lori-gawron",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05866419",
"publication_url": "https://clinicaltrials.gov/study/NCT05866419",
"title": "Safety and Performance of the ThecaFlex DRx™ System Port and Catheter for Chronic Intrathecal Access, Cerebrospinal Fluid (CSF) Aspiration, and DElivery of Nusinersen in Spinal Muscular Atrophy (SMA) Patients Resistant to Lumbar PunctuRE Trial (PIERRE)",
"has_exemption": false,
"start_date": "2023-11-27",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Alcyone Therapeutics, Inc",
"sponsor_slug": "alcyone-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05996627",
"publication_url": "https://clinicaltrials.gov/study/NCT05996627",
"title": "Randomized Phase II Study of Belumosudil vs. Placebo for Preemptive Treatment of Chronic Graft Versus Host Disease",
"has_exemption": false,
"start_date": "2023-12-06",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Fred Hutchinson Cancer Center",
"sponsor_slug": "fred-hutchinson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05383742",
"publication_url": "https://clinicaltrials.gov/study/NCT05383742",
"title": "A Phase II, Randomized, Open-Label Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous Meningitis: Improved Management With Antimicrobial AGents Isoniazid rifampiciN LinEzolid for TBM (IMAGINE-TBM)",
"has_exemption": false,
"start_date": "2023-12-07",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Allergy and Infectious Diseases (NIAID)",
"sponsor_slug": "national-institute-of-allergy-and-infectious-diseases-niaid",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05822362",
"publication_url": "https://clinicaltrials.gov/study/NCT05822362",
"title": "Cannabidiol for Individuals at Risk for Alzheimer's Disease: A Randomized Placebo Controlled Trial",
"has_exemption": false,
"start_date": "2024-01-19",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06312189",
"publication_url": "https://clinicaltrials.gov/study/NCT06312189",
"title": "Open-Label Study of Valbenazine for the Treatment of Chorea Associated With Huntington Disease in Canada",
"has_exemption": false,
"start_date": "2024-04-24",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Neurocrine Biosciences",
"sponsor_slug": "neurocrine-biosciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06340711",
"publication_url": "https://clinicaltrials.gov/study/NCT06340711",
"title": "Phase II Study of Suratadenoturev (OBP-301) in Combination With Pembrolizumab in PD-L1-Negative or Immunotherapy-refractory Esophagogastric Adenocarcinoma",
"has_exemption": false,
"start_date": "2024-04-25",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06346067",
"publication_url": "https://clinicaltrials.gov/study/NCT06346067",
"title": "A Randomized, Open-label Phase III Study in Patients With Previously Treated Unresectable or Metastatic NRAS Mutant Cutaneous Melanoma Comparing the Combination of Naporafenib + Trametinib to Physician's Choice of Therapy (Dacarbazine, Temozolomide or Trametinib Monotherapy) With a Dose Optimization lead-in [SEACRAFT-2]",
"has_exemption": false,
"start_date": "2024-04-29",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Erasca, Inc.",
"sponsor_slug": "erasca-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05992831",
"publication_url": "https://clinicaltrials.gov/study/NCT05992831",
"title": "Transcranial Magnetic Stimulation for MCI: A Phase II Dose-Response Study",
"has_exemption": false,
"start_date": "2024-06-18",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University of South Carolina",
"sponsor_slug": "medical-university-of-south-carolina",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06411210",
"publication_url": "https://clinicaltrials.gov/study/NCT06411210",
"title": "Obesity Complicating Type 1 Diabetes in Young Adults: Physiology and Impact of GLP-1 Analogue Anti-obesity Treatment on Cardiometabolic Risk Factors",
"has_exemption": false,
"start_date": "2024-07-16",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06439953",
"publication_url": "https://clinicaltrials.gov/study/NCT06439953",
"title": "Impact of Prophylactic Use of Irrisept Irrigation System for Spinal Instrumentation",
"has_exemption": false,
"start_date": "2024-10-01",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Rhode Island Hospital",
"sponsor_slug": "rhode-island-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06712420",
"publication_url": "https://clinicaltrials.gov/study/NCT06712420",
"title": "Neoadjuvant Chemotherapy Versus Upfront Surgery for Locally Advanced Resectable Gall Bladder Cancer : A Randomized Trial",
"has_exemption": false,
"start_date": "2025-01-01",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Rajiv Gandhi Cancer Institute & Research Center, India",
"sponsor_slug": "rajiv-gandhi-cancer-institute-research-center-india",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06722755",
"publication_url": "https://clinicaltrials.gov/study/NCT06722755",
"title": "Optimizing Adherence to the Treatment of Sleep Apnea Among Patients With Stroke Undergoing Inpatient Rehabilitation",
"has_exemption": false,
"start_date": "2025-01-15",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Washington",
"sponsor_slug": "university-of-washington",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06792539",
"publication_url": "https://clinicaltrials.gov/study/NCT06792539",
"title": "A Multi-Center, Prospective, Non-Randomized, Pivotal Trial Evaluating the Safety and Effectiveness of the Polymotion Hip Resurfacing System",
"has_exemption": false,
"start_date": "2025-01-22",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "JointMedica Inc.",
"sponsor_slug": "jointmedica-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06788990",
"publication_url": "https://clinicaltrials.gov/study/NCT06788990",
"title": "A Multicenter, Randomized, Double-blind, Phase 2/3 Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab for First-Line Treatment of PD-L1-positive, Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2025-01-28",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Bicara Therapeutics",
"sponsor_slug": "bicara-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06767514",
"publication_url": "https://clinicaltrials.gov/study/NCT06767514",
"title": "A Randomized, Double-blinded, Multiregional Phase 3 Study of Ivonescimab Versus Pembrolizumab for the First-line Treatment of Metastatic Non-small Cell Lung Cancer in Patients Whose Tumors Demonstrate High PD-L1 Expression",
"has_exemption": false,
"start_date": "2025-02-27",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Summit Therapeutics",
"sponsor_slug": "summit-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06859268",
"publication_url": "https://clinicaltrials.gov/study/NCT06859268",
"title": "A Phase 3b, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Retatrutide Treatment in the Maintenance of Weight Reduction in Individuals With Obesity",
"has_exemption": false,
"start_date": "2025-03-05",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06858254",
"publication_url": "https://clinicaltrials.gov/study/NCT06858254",
"title": "Standard Optimization of Autologous Stem Cells by Intranasal and Intravenous Administration to Treat Parkinson's Disease and Atypical Parkinsonism",
"has_exemption": false,
"start_date": "2025-04-01",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Apeiron Research Center",
"sponsor_slug": "apeiron-research-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06866275",
"publication_url": "https://clinicaltrials.gov/study/NCT06866275",
"title": "Suramin for the Treatment of Autism Trial (STAT): A Randomized, Double Blind, Crossover Trial of KZ101 in a Male Pediatric Population With Autism Spectrum Disorder",
"has_exemption": false,
"start_date": "2025-04-09",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Hospital of Orange County",
"sponsor_slug": "childrens-hospital-of-orange-county",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06929286",
"publication_url": "https://clinicaltrials.gov/study/NCT06929286",
"title": "COMparative Prospective Assessment Through Clinically Integrated Randomized Trials Evaluating Intravesical Treatments: The COMPARE IT Trial",
"has_exemption": false,
"start_date": "2025-04-11",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06931821",
"publication_url": "https://clinicaltrials.gov/study/NCT06931821",
"title": "Functional ElectroAnatomiC Isochronal Late Activation Mapping for Empiric VT Ablation Trial",
"has_exemption": false,
"start_date": "2025-04-15",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Arizona",
"sponsor_slug": "university-of-arizona",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06873581",
"publication_url": "https://clinicaltrials.gov/study/NCT06873581",
"title": "A Pivotal Study of Voro Urologic Scaffold for the Treatment of Post Prostatectomy Stress Urinary Incontinence (ARID II)",
"has_exemption": false,
"start_date": "2025-04-18",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Levee Medical, Inc.",
"sponsor_slug": "levee-medical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06899711",
"publication_url": "https://clinicaltrials.gov/study/NCT06899711",
"title": "A Prospective Study to Evaluate the Protective Effects of External Cranial Prosthesis on Incidence of Sunken Flap Syndrome in Decompressive Craniectomy Patients",
"has_exemption": false,
"start_date": "2025-04-26",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06921148",
"publication_url": "https://clinicaltrials.gov/study/NCT06921148",
"title": "The Utility of Silk Bioprotein as a Wound Dressing in Female-to-Male Double-Incision Mastectomy",
"has_exemption": false,
"start_date": "2025-04-30",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06636136",
"publication_url": "https://clinicaltrials.gov/study/NCT06636136",
"title": "Transtibial Osseointegration Surgery Study (TOSS)",
"has_exemption": false,
"start_date": "2025-05-20",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Walter Reed National Military Medical Center",
"sponsor_slug": "walter-reed-national-military-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06957704",
"publication_url": "https://clinicaltrials.gov/study/NCT06957704",
"title": "Evaluation of the Efficacy and Safety of Subcutaneous Ketamine in the Treatment of Depressive Episode With Suicidal Ideation and/or Behavior in Adolescents",
"has_exemption": false,
"start_date": "2025-05-31",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Federal University of São Paulo",
"sponsor_slug": "federal-university-of-sao-paulo",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06852365",
"publication_url": "https://clinicaltrials.gov/study/NCT06852365",
"title": "Resistant Starch Usage in Polycystic Ovary Syndrome: Impact on Cardiometabolic Dysfunction and the Gut Microbiome (CORS-PCOS)",
"has_exemption": false,
"start_date": "2025-06-10",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06405607",
"publication_url": "https://clinicaltrials.gov/study/NCT06405607",
"title": "Psilocybin vs Ketamine for Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2025-06-12",
"completion_date": "2028-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Iowa",
"sponsor_slug": "university-of-iowa",
"status": "ongoing",
"is_pact": false,
"days_late": null
}
]
}