HTTP 200 OK
Allow: GET, POST, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"recordsFiltered": 47012,
"recordsTotal": 47012,
"next": "http://fdaaa.trialstracker.net/api/trials/?format=api&length=300&ordering=days_late&start=43200",
"previous": "http://fdaaa.trialstracker.net/api/trials/?format=api&length=300&ordering=days_late&start=42600",
"results": [
{
"registry_id": "NCT07160608",
"publication_url": "https://clinicaltrials.gov/study/NCT07160608",
"title": "Phase 2, Randomized, Double-Blind, Placebo-controlled, Parallel-Group, Multicenter Study to Evaluate the Safety and Efficacy of Tarperprumig in Adult Participants With Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (I TRANSCEND)",
"has_exemption": false,
"start_date": "2025-10-31",
"completion_date": "2027-10-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Alexion Pharmaceuticals, Inc.",
"sponsor_slug": "alexion-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06676319",
"publication_url": "https://clinicaltrials.gov/study/NCT06676319",
"title": "A Randomized, Phase 2, Double-blind, Placebo-controlled, Parallel-group, 2-arm Study to Investigate the Efficacy, Safety, and Tolerability of Subcutaneous Lunsekimig (SAR443765) in Adult Participants With High-risk Asthma Who Are Not Currently Eligible for Biologic Treatment",
"has_exemption": false,
"start_date": "2024-11-07",
"completion_date": "2027-10-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07108283",
"publication_url": "https://clinicaltrials.gov/study/NCT07108283",
"title": "A Phase 2, Multicenter, Randomized, Placebo-Controlled, Double-Blind, Dose-Ranging Trial to Evaluate the Efficacy and Safety of Zasocitinib in Participants With Nonsegmental Vitiligo",
"has_exemption": false,
"start_date": "2025-11-03",
"completion_date": "2027-10-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05030428",
"publication_url": "https://clinicaltrials.gov/study/NCT05030428",
"title": "A Randomized, Double-blind, Placebo-controlled, Multicenter Trial, Assessing the Impact of Inclisiran on Major Adverse Cardiovascular Events in Participants With Established Cardiovascular Disease (VICTORION-2 PREVENT)",
"has_exemption": false,
"start_date": "2021-11-23",
"completion_date": "2027-10-13",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06307665",
"publication_url": "https://clinicaltrials.gov/study/NCT06307665",
"title": "A Randomized, Double-blind, Multicenter, Parallel-group, Phase IIIb 52 Week Study Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered as Needed in Participants 12 to < 18 Years of Age With Asthma (ACADIA)",
"has_exemption": false,
"start_date": "2024-05-20",
"completion_date": "2027-10-13",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07215234",
"publication_url": "https://clinicaltrials.gov/study/NCT07215234",
"title": "A Phase 1/2, Study to Evaluate the Safety, Tolerability, and Efficacy of One-time Intravitreal Dose of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration",
"has_exemption": false,
"start_date": "2025-10-09",
"completion_date": "2027-10-13",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07237100",
"publication_url": "https://clinicaltrials.gov/study/NCT07237100",
"title": "A Pilot Study of Mirdametinib in Patients With Advanced Melanoma With an NF1 Mutation",
"has_exemption": false,
"start_date": "2025-10-13",
"completion_date": "2027-10-13",
"has_results": false,
"results_due": false,
"sponsor_name": "Kevin Kim, MD",
"sponsor_slug": "kevin-kim-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05077735",
"publication_url": "https://clinicaltrials.gov/study/NCT05077735",
"title": "Stereotactic Biopsy Split-Course Radiation Therapy - Diffuse Midline Glioma (SPORT-DMG)",
"has_exemption": false,
"start_date": "2021-10-11",
"completion_date": "2027-10-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05465954",
"publication_url": "https://clinicaltrials.gov/study/NCT05465954",
"title": "Efficacy and Safety Study of Neoadjuvant Efineptakin Alfa (NT-I7) and Pembrolizumab in Recurrent Glioblastoma",
"has_exemption": false,
"start_date": "2023-01-24",
"completion_date": "2027-10-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05922930",
"publication_url": "https://clinicaltrials.gov/study/NCT05922930",
"title": "Phase I/II Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells Delivered Intraperitoneally for the Management of Platinum Resistant Ovarian Cancer, Mesonephric-like Adenocarcinoma, and Pancreatic Cancer",
"has_exemption": false,
"start_date": "2023-10-11",
"completion_date": "2027-10-15",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06476704",
"publication_url": "https://clinicaltrials.gov/study/NCT06476704",
"title": "Phase 2 Study of Preoperative RAdiation Therapy With Concomitant Liposomal Transcrocetin (L-TC) in Soft tISsue Sarcomas",
"has_exemption": false,
"start_date": "2025-06-01",
"completion_date": "2027-10-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Institut de Cancerologie Strasbourg Europe",
"sponsor_slug": "institut-de-cancerologie-strasbourg-europe",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06202066",
"publication_url": "https://clinicaltrials.gov/study/NCT06202066",
"title": "A Phase II Study of Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) in Patients With Progressing Metastatic Neuroendocrine Carcinomas (NECs)",
"has_exemption": false,
"start_date": "2025-11-15",
"completion_date": "2027-10-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Roswell Park Cancer Institute",
"sponsor_slug": "roswell-park-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07222852",
"publication_url": "https://clinicaltrials.gov/study/NCT07222852",
"title": "Cardiovascular Protection After Preeclampsia With Enalapril",
"has_exemption": false,
"start_date": "2025-11-15",
"completion_date": "2027-10-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Women and Infants Hospital of Rhode Island",
"sponsor_slug": "women-and-infants-hospital-of-rhode-island",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06112314",
"publication_url": "https://clinicaltrials.gov/study/NCT06112314",
"title": "A Phase 3 Randomized, Controlled Study of IMC-F106C Plus Nivolumab Versus Nivolumab Regimens in HLA-A*02:01-Positive Participants With Previously Untreated Advanced Melanoma (PRISM-MEL-301",
"has_exemption": false,
"start_date": "2024-06-05",
"completion_date": "2027-10-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Immunocore Ltd",
"sponsor_slug": "immunocore-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07071623",
"publication_url": "https://clinicaltrials.gov/study/NCT07071623",
"title": "A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis in Women",
"has_exemption": false,
"start_date": "2025-11-10",
"completion_date": "2027-10-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227012",
"publication_url": "https://clinicaltrials.gov/study/NCT07227012",
"title": "AN INTERVENTIONAL OPEN-LABEL PHASE 1B/2 STUDY TO EVALUATE SAFETY, PHARMACOKINETICS, AND PRELIMINARY EFFICACY OF PF-08634404 AS MONOTHERAPY AND COMBINATION THERAPY IN ADULT PARTICIPANTS WITH UNRESECTABLE LOCALLY ADVANCED OR METASTATIC HEPATOCELLULAR CARCINOMA",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2027-10-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04747613",
"publication_url": "https://clinicaltrials.gov/study/NCT04747613",
"title": "An Open Label, Multicenter Roll-over Extension Program (REP) to Characterize the Long-term Safety and Tolerability of Iptacopan (LNP023) in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Completed PNH Phase 2 and Phase3 Studies With Iptacopan",
"has_exemption": false,
"start_date": "2021-07-27",
"completion_date": "2027-10-19",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05118854",
"publication_url": "https://clinicaltrials.gov/study/NCT05118854",
"title": "A Phase II Study of Neoadjuvant Sotorasib in Combination With Cisplatin or Carboplatin and Pemetrexed for Surgically Resectable Stage IIA-IIIB Non-Squamous Non-Small Cell Lung Cancer With a KRAS p.G12C Mutation",
"has_exemption": false,
"start_date": "2022-03-30",
"completion_date": "2027-10-20",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05545826",
"publication_url": "https://clinicaltrials.gov/study/NCT05545826",
"title": "Vibrotactile Coordinated Reset: A Treatment for Early Stage Parkinson's Disease",
"has_exemption": false,
"start_date": "2025-04-01",
"completion_date": "2027-10-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06845319",
"publication_url": "https://clinicaltrials.gov/study/NCT06845319",
"title": "Anthracycline-Free Neoadjuvant Chemoimmunotherapy for Triple Negative Breast Cancer Patients With Cardiomyopathy or at an Elevated Risk of Cardiotoxicity (NeoCARD): A Response Adapted Single-arm Phase 2 Trial",
"has_exemption": false,
"start_date": "2025-10-20",
"completion_date": "2027-10-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University of South Carolina",
"sponsor_slug": "medical-university-of-south-carolina",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02861573",
"publication_url": "https://clinicaltrials.gov/study/NCT02861573",
"title": "Phase Ib/II Trial of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (mCRPC) (KEYNOTE-365)",
"has_exemption": false,
"start_date": "2016-11-17",
"completion_date": "2027-10-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT05805605",
"publication_url": "https://clinicaltrials.gov/study/NCT05805605",
"title": "Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning (RIC) With Post-Transplant Cytoxan (PTCy) for the Treatment of Hematological Diseases",
"has_exemption": false,
"start_date": "2023-05-01",
"completion_date": "2027-10-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Masonic Cancer Center, University of Minnesota",
"sponsor_slug": "masonic-cancer-center-university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06656390",
"publication_url": "https://clinicaltrials.gov/study/NCT06656390",
"title": "A First-in-Human, Open-Label, Multi-Center Phase I/II Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ALK201 for Injection in Adult Participants With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2024-10-24",
"completion_date": "2027-10-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Shanghai Allink Biotherapeutics Co., Ltd.",
"sponsor_slug": "shanghai-allink-biotherapeutics-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02133196",
"publication_url": "https://clinicaltrials.gov/study/NCT02133196",
"title": "A Phase II Study Using Autologous Young Tumor-Infiltrating Lymphocytes Derived From Patients With Non-Small Cell Lung Cancer Following Non-Myeloablative Lymphocyte Depleting Preparative Regimen",
"has_exemption": false,
"start_date": "2014-10-23",
"completion_date": "2027-10-23",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02332668",
"publication_url": "https://clinicaltrials.gov/study/NCT02332668",
"title": "A Phase I/II Study of Pembrolizumab (MK-3475) in Children With Advanced Melanoma or a PD-L1 Positive Advanced, Relapsed or Refractory Solid Tumor or Lymphoma (KEYNOTE-051)",
"has_exemption": false,
"start_date": "2015-03-18",
"completion_date": "2027-10-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT05012371",
"publication_url": "https://clinicaltrials.gov/study/NCT05012371",
"title": "A Phase II Study of Lenvatinib Plus Everolimus Versus Cabozantinib in Patients With Metastatic Renal Cell Carcinoma That Progressed on A PD-1/PD-L1 Checkpoint Inhibitor",
"has_exemption": false,
"start_date": "2022-02-16",
"completion_date": "2027-10-25",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06966453",
"publication_url": "https://clinicaltrials.gov/study/NCT06966453",
"title": "A Phase 1b/2, Open-Label, Multicohort Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer",
"has_exemption": false,
"start_date": "2025-06-30",
"completion_date": "2027-10-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06941870",
"publication_url": "https://clinicaltrials.gov/study/NCT06941870",
"title": "Prospective Interventional Study of Effectiveness of Efanesoctocog Alfa Prophylaxis on Synovial Hypertrophy in Patients With Hemophilia A",
"has_exemption": false,
"start_date": "2025-09-23",
"completion_date": "2027-10-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03326336",
"publication_url": "https://clinicaltrials.gov/study/NCT03326336",
"title": "A Phase 1/2a, Open-Label, Non-Randomized, Dose-Escalation Study to Evaluate the Safety and Tolerability of GS030 in Subjects With Retinitis Pigmentosa",
"has_exemption": false,
"start_date": "2018-09-26",
"completion_date": "2027-10-26",
"has_results": false,
"results_due": false,
"sponsor_name": "GenSight Biologics",
"sponsor_slug": "gensight-biologics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06435312",
"publication_url": "https://clinicaltrials.gov/study/NCT06435312",
"title": "An Open-Label Extension Study to Evaluate the Long-Term Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Activity of Zilucoplan in Pediatric Study Participants With Acetylcholine Receptor Antibody Positive Generalized Myasthenia Gravis",
"has_exemption": false,
"start_date": "2024-11-19",
"completion_date": "2027-10-26",
"has_results": false,
"results_due": false,
"sponsor_name": "UCB Biopharma SRL",
"sponsor_slug": "ucb-biopharma-srl",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06990880",
"publication_url": "https://clinicaltrials.gov/study/NCT06990880",
"title": "A Phase 1/2 First-Time-In-Human, Open-Label, Multicenter, Dose Escalation and Expansion Study of GSK5458514 PSMA Targeting T Cell Engager Alone or in Combination With Other Anti-Cancer Agents in Adult Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)",
"has_exemption": false,
"start_date": "2025-06-12",
"completion_date": "2027-10-26",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07166952",
"publication_url": "https://clinicaltrials.gov/study/NCT07166952",
"title": "Peripheral Nerve Stimulation With the SPRINT® System in Chronic Posterior Sacroiliac Joint Complex Pain",
"has_exemption": false,
"start_date": "2025-10-26",
"completion_date": "2027-10-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University of South Carolina",
"sponsor_slug": "medical-university-of-south-carolina",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05923073",
"publication_url": "https://clinicaltrials.gov/study/NCT05923073",
"title": "A Phase 3, Multicenter, Randomized, Platform Study of p19 Inhibition of the IL-23 Pathway to Establish Efficacy in Pediatric Crohn's Disease",
"has_exemption": false,
"start_date": "2024-03-13",
"completion_date": "2027-10-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07223645",
"publication_url": "https://clinicaltrials.gov/study/NCT07223645",
"title": "Handgrip Training and Brain Blood Flow Regulation",
"has_exemption": false,
"start_date": "2025-10-27",
"completion_date": "2027-10-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Florida State University",
"sponsor_slug": "florida-state-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04624204",
"publication_url": "https://clinicaltrials.gov/study/NCT04624204",
"title": "A Randomized, Double-blind, Placebo-controlled Phase 3 Study of Pembrolizumab (MK-3475) in Combination With Concurrent Chemoradiation Therapy Followed by Pembrolizumab With or Without Olaparib (MK-7339), Compared to Concurrent Chemoradiation Therapy Alone in Participants With Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC)",
"has_exemption": false,
"start_date": "2020-12-08",
"completion_date": "2027-10-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06090539",
"publication_url": "https://clinicaltrials.gov/study/NCT06090539",
"title": "A Phase 1/2, Multi-Center, Open-Label, Dose-Finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of BMS-986458, Alone and in Combination With Anti-lymphoma Agents in Participants With Relapsed/Refractory Non-Hodgkin Lymphomas (R/R NHL)",
"has_exemption": false,
"start_date": "2023-12-29",
"completion_date": "2027-10-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06293053",
"publication_url": "https://clinicaltrials.gov/study/NCT06293053",
"title": "A Multicenter Open-label Study to Investigate the Pharmacokinetics and Safety of Dupilumab in Participants ≥6 Months to <18 Years of Age With Prurigo Nodularis",
"has_exemption": false,
"start_date": "2024-05-15",
"completion_date": "2027-10-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06959771",
"publication_url": "https://clinicaltrials.gov/study/NCT06959771",
"title": "Base Editing Hematopoietic Stem Cell and BE T Cell Gene Therapy for CD40L-HyperIgM Syndrome-Single Patient Study",
"has_exemption": false,
"start_date": "2025-07-16",
"completion_date": "2027-10-28",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Allergy and Infectious Diseases (NIAID)",
"sponsor_slug": "national-institute-of-allergy-and-infectious-diseases-niaid",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02843945",
"publication_url": "https://clinicaltrials.gov/study/NCT02843945",
"title": "Initial Feasibility Study to Evaluate the Safety and Efficacy of the Permanently Implantable LDR CivaSheet® in Combination With External Beam Radiation in the Treatment of Pancreatic Cancer",
"has_exemption": false,
"start_date": "2017-05-31",
"completion_date": "2027-10-29",
"has_results": false,
"results_due": false,
"sponsor_name": "CivaTech Oncology",
"sponsor_slug": "civatech-oncology",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05584124",
"publication_url": "https://clinicaltrials.gov/study/NCT05584124",
"title": "Neuromodulation for Rehabilitation of Post-Stroke Fatigue: An rTMS Pilot Study",
"has_exemption": false,
"start_date": "2023-04-10",
"completion_date": "2027-10-29",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06680661",
"publication_url": "https://clinicaltrials.gov/study/NCT06680661",
"title": "ABBA CORD: Double Umbilical Cord Blood Transplants With Abatacept for Graft Versus Host Disease Prophylaxis",
"has_exemption": false,
"start_date": "2025-02-25",
"completion_date": "2027-10-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Leland Metheny",
"sponsor_slug": "leland-metheny",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06117254",
"publication_url": "https://clinicaltrials.gov/study/NCT06117254",
"title": "Evaluating Device-based Rehabilitation for Veterans With Functional Hearing Difficulties: A Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2025-03-09",
"completion_date": "2027-10-29",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03763162",
"publication_url": "https://clinicaltrials.gov/study/NCT03763162",
"title": "A Phase 2 Study of Daratumumab, Bortezomib, and Dexamethasone (DVd), Followed by Daratumumab, Ixazomib, and Dexamethasone (DId) for Relapsed and/or Refractory Myeloma",
"has_exemption": false,
"start_date": "2019-01-17",
"completion_date": "2027-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04752774",
"publication_url": "https://clinicaltrials.gov/study/NCT04752774",
"title": "An Integrated Phase I/II, Multicentre, Double-blind, Randomised, Dysport and Placebo-controlled, Dose Escalation and Dose-finding Study to Evaluate the Safety and Efficacy of IPN10200 in the Treatment of Adult Upper Limb Spasticity.",
"has_exemption": false,
"start_date": "2021-04-29",
"completion_date": "2027-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Ipsen",
"sponsor_slug": "ipsen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05018286",
"publication_url": "https://clinicaltrials.gov/study/NCT05018286",
"title": "An Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome.",
"has_exemption": false,
"start_date": "2021-07-13",
"completion_date": "2027-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "VectivBio AG",
"sponsor_slug": "vectivbio-ag",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04940286",
"publication_url": "https://clinicaltrials.gov/study/NCT04940286",
"title": "Phase II Study of Neoadjuvant Gemcitabine, Nab-paclitaxel, Durvalumab (MEDI4736) (Anti-PD-L1), and Oleclumab (Anti-CD73) in the Treatment of Resectable/Borderline Resectable Primary Pancreatic Adenocarcinoma",
"has_exemption": false,
"start_date": "2021-09-28",
"completion_date": "2027-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05663710",
"publication_url": "https://clinicaltrials.gov/study/NCT05663710",
"title": "Phase 1b/2 Study of Combination 177Lu Girentuximab Plus Cabozantinib and Nivolumab in Treatment naïve Patients With Advanced Clear Cell RCC",
"has_exemption": false,
"start_date": "2023-06-30",
"completion_date": "2027-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05874401",
"publication_url": "https://clinicaltrials.gov/study/NCT05874401",
"title": "A Randomized, Double-Blind, Placebo-Controlled Study of Trilaciclib vs Placebo in Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC) Receiving Topotecan Chemotherapy",
"has_exemption": false,
"start_date": "2023-10-18",
"completion_date": "2027-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Pharmacosmos A/S",
"sponsor_slug": "pharmacosmos-as",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05922904",
"publication_url": "https://clinicaltrials.gov/study/NCT05922904",
"title": "PET Adapted Brentuximab Vedotin and Pembrolizumab in Combination With Doxorubicin and Dacarbazine in Classic Hodgkin Lymphoma",
"has_exemption": false,
"start_date": "2023-12-14",
"completion_date": "2027-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05970172",
"publication_url": "https://clinicaltrials.gov/study/NCT05970172",
"title": "A Phase 3, Open-label, Uncontrolled Study to Evaluate the Activity, Safety, Pharmacokinetics and Pharmacodynamics of Roxadustat for the Treatment of Anemia in Pediatric Participants With Chronic Kidney Disease",
"has_exemption": false,
"start_date": "2024-01-16",
"completion_date": "2027-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Astellas Pharma Global Development, Inc.",
"sponsor_slug": "astellas-pharma-global-development-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05945355",
"publication_url": "https://clinicaltrials.gov/study/NCT05945355",
"title": "Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA)",
"has_exemption": false,
"start_date": "2024-08-01",
"completion_date": "2027-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Duke University",
"sponsor_slug": "duke-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06596135",
"publication_url": "https://clinicaltrials.gov/study/NCT06596135",
"title": "Open-Label Extension Study of Setmelanotide in Patients With a Rare Genetic, Syndromic or Acquired Disease of the MC4R Pathway",
"has_exemption": false,
"start_date": "2024-10-21",
"completion_date": "2027-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Rhythm Pharmaceuticals, Inc.",
"sponsor_slug": "rhythm-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06220474",
"publication_url": "https://clinicaltrials.gov/study/NCT06220474",
"title": "Therapeutic Efficacy and Safety of Non-Invasive Radiofrequency Treatment in Patients With Refractory Meibomian Gland Dysfunction: A Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2024-10-22",
"completion_date": "2027-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Hong Kong",
"sponsor_slug": "the-university-of-hong-kong",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06686108",
"publication_url": "https://clinicaltrials.gov/study/NCT06686108",
"title": "Safety and Efficacy Study of Demethylating Agents With Venetoclax in Preventing Recurrence of High-risk T-cell Lymphoblastic Lymphoma/Leukemia After Transplantation",
"has_exemption": false,
"start_date": "2024-10-30",
"completion_date": "2027-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine",
"sponsor_slug": "shanghai-general-hospital-shanghai-jiao-tong-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06385262",
"publication_url": "https://clinicaltrials.gov/study/NCT06385262",
"title": "Safety, Efficacy, and Tumor Immune Microenvironment Changes With Neoadjuvant Chemotherapy and Cemiplimab With or Without Alirocumab in Stage 1B-3A Non-Small Cell Lung Cancer: TOP 2301",
"has_exemption": false,
"start_date": "2025-03-17",
"completion_date": "2027-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Duke University",
"sponsor_slug": "duke-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07043400",
"publication_url": "https://clinicaltrials.gov/study/NCT07043400",
"title": "A Phase 3, Multi-Center, Randomized, Open-Label Clinical Study of Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy as First-Line Treatment in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma",
"has_exemption": false,
"start_date": "2025-08-27",
"completion_date": "2027-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "BeOne Medicines",
"sponsor_slug": "beone-medicines",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07076082",
"publication_url": "https://clinicaltrials.gov/study/NCT07076082",
"title": "Vascular Trial Associated Registry Pilot: Antiplatelet Therapies for Patients Undergoing Lower Extremity Endovascular Revascularization",
"has_exemption": false,
"start_date": "2025-10-15",
"completion_date": "2027-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Corewell Health West",
"sponsor_slug": "corewell-health-west",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06616155",
"publication_url": "https://clinicaltrials.gov/study/NCT06616155",
"title": "Study of JAK Inhibition in Stem-Like Prostate Cancer (JASPER): A Phase 1b/2a Multicenter Study of Ruxolitinib and Enzalutamide in Castration Resistant Prostate Cancer",
"has_exemption": false,
"start_date": "2025-10-30",
"completion_date": "2027-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan Rogel Cancer Center",
"sponsor_slug": "university-of-michigan-rogel-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06967558",
"publication_url": "https://clinicaltrials.gov/study/NCT06967558",
"title": "The Role of Islet GLP-1 in the Pathogenesis of Prediabetes",
"has_exemption": false,
"start_date": "2025-11-01",
"completion_date": "2027-10-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT01208389",
"publication_url": "https://clinicaltrials.gov/study/NCT01208389",
"title": "A Follow-On Study to Evaluate the Safety of Re-Administration of Adeno-Associated Viral Vector Containing the Gene for Human RPE65 [AAV2-hRPE65v2] to the Contralateral Eye in Subjects With Leber Congenital Amaurosis (LCA) Previously Enrolled in a Phase 1 Study",
"has_exemption": false,
"start_date": "2010-11-30",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Spark Therapeutics, Inc.",
"sponsor_slug": "spark-therapeutics-inc",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT01424982",
"publication_url": "https://clinicaltrials.gov/study/NCT01424982",
"title": "Phase II Study of Combination of Hyper-CVAD and Ponatinib in Patients With Philadelphia (PH) Chromosome Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia (ALL)",
"has_exemption": false,
"start_date": "2011-10-05",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT01696734",
"publication_url": "https://clinicaltrials.gov/study/NCT01696734",
"title": "Treatment Protocol for the Compassionate Use of Domperidone",
"has_exemption": false,
"start_date": "2012-10-23",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT01720836",
"publication_url": "https://clinicaltrials.gov/study/NCT01720836",
"title": "Study of the Immunogenicity of the MUC1 Peptide - Poly-ICLC (Polyinosinic-polycytidylic Acid Stabilized With Polylysine and Carboxymethylcellulose) OR HILTONOL™ Adjuvant Vaccine in Patients With Localized and Locally Advanced Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2012-11-30",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Olivera Finn",
"sponsor_slug": "olivera-finn",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT01797523",
"publication_url": "https://clinicaltrials.gov/study/NCT01797523",
"title": "A Phase II, Single-Arm Study of RAD001 (Everolimus), Letrozole, and Metformin in Patients With Advanced or Recurrent Endometrial Carcinoma",
"has_exemption": false,
"start_date": "2013-10-07",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02043691",
"publication_url": "https://clinicaltrials.gov/study/NCT02043691",
"title": "Evaluation of All-Cause Mortality and Pulmonary Morbidity in Treating Juxtarenal, Suprarenal and Thoracoabdominal Aortic Pathologies Using the Cook Custom Aortic Endograft, the Zenith t-Branch Endovascular Graft and Surgeon-Modified Endografts",
"has_exemption": false,
"start_date": "2014-06-30",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02250937",
"publication_url": "https://clinicaltrials.gov/study/NCT02250937",
"title": "Allogeneic Transplantation Using Venetoclax, Timed Sequential Busulfan,Cladribine, and Fludarabine Conditioning in Patients With AML and MDS",
"has_exemption": false,
"start_date": "2014-10-27",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02876107",
"publication_url": "https://clinicaltrials.gov/study/NCT02876107",
"title": "A Randomized Phase II Study of Neoadjuvant Carboplatin/Paclitaxel (CT) Versus Panitumumab/Carboplatin/Paclitaxel (PaCT) Followed by Anthracycline-Containing Regimen for Newly Diagnosed Primary Triple-Negative Inflammatory Breast Cancer",
"has_exemption": false,
"start_date": "2016-10-06",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03307616",
"publication_url": "https://clinicaltrials.gov/study/NCT03307616",
"title": "Phase II Study of Neoadjuvant Checkpoint Blockade in Patients With Surgically Resectable Undifferentiated Pleomorphic Sarcoma and Dedifferentiated Liposarcoma",
"has_exemption": false,
"start_date": "2017-10-04",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03359954",
"publication_url": "https://clinicaltrials.gov/study/NCT03359954",
"title": "PRECISE: Preoperative Radiotherapy to Elicit Critical Immune Stimulating Effects",
"has_exemption": false,
"start_date": "2017-11-16",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04040062",
"publication_url": "https://clinicaltrials.gov/study/NCT04040062",
"title": "Pilot Study: Evaluating the Feasibility of Repetitive Transcranial Magnetic Stimulation Treatment Delivered at Individual-based, SCC-determined Frequency in Subjects Suffering From Major Depressive Disorder",
"has_exemption": false,
"start_date": "2019-06-25",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Los Angeles",
"sponsor_slug": "university-of-california-los-angeles",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04133675",
"publication_url": "https://clinicaltrials.gov/study/NCT04133675",
"title": "A Single-Blind, Randomized Study of the BTL EmsellaTM Chair Versus Sham for the Treatment of Stress Urinary Incontinence",
"has_exemption": false,
"start_date": "2019-12-18",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Corewell Health East",
"sponsor_slug": "corewell-health-east",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03915431",
"publication_url": "https://clinicaltrials.gov/study/NCT03915431",
"title": "A Phase 1/2 Randomized Study to Evaluate the Safety and Tolerability of Intracarotid Artery Administration of NCS-01 in Patients With Acute Ischemic Stroke",
"has_exemption": false,
"start_date": "2020-02-27",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NC Medial Research Inc",
"sponsor_slug": "nc-medial-research-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04563507",
"publication_url": "https://clinicaltrials.gov/study/NCT04563507",
"title": "CIMER: Combined Immunotherapies in Metastatic ER+ Breast Cancer",
"has_exemption": false,
"start_date": "2020-11-12",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04570423",
"publication_url": "https://clinicaltrials.gov/study/NCT04570423",
"title": "A Multicenter, Open-Label, Phase 2 Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Patients With Solid Tumors or Lymphomas and Treated With Myelosuppressive Chemotherapy",
"has_exemption": false,
"start_date": "2021-05-20",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Spectrum Pharmaceuticals, Inc",
"sponsor_slug": "spectrum-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04858334",
"publication_url": "https://clinicaltrials.gov/study/NCT04858334",
"title": "APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation",
"has_exemption": false,
"start_date": "2021-06-22",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04946370",
"publication_url": "https://clinicaltrials.gov/study/NCT04946370",
"title": "Phase I/II Trial of Pembrolizumab and Androgen-receptor Inhibitor With or Without 225Ac-J591 for Progressive Metastatic Castration Resistant Prostate Cancer",
"has_exemption": false,
"start_date": "2021-08-12",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04851717",
"publication_url": "https://clinicaltrials.gov/study/NCT04851717",
"title": "A Phase 2/3, Prospective, Open-label Trial Evaluating the Efficacy, Safety, and Pharmacokinetics of Remimazolam for Intravenous Sedation in Paediatric Patients Undergoing Diagnostic and/or Therapeutic Procedures",
"has_exemption": false,
"start_date": "2021-11-15",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Acacia Pharma Ltd",
"sponsor_slug": "acacia-pharma-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04852328",
"publication_url": "https://clinicaltrials.gov/study/NCT04852328",
"title": "Non-Randomized Phase 2 Trial of Three Schedules of CUE-101 Administered Before Surgery or Definitive Chemoradiation Therapy in HLA-A*0201 Positive Patients With Locally Advanced, HPV16-Positive Oropharyngeal Squamous-Cell Carcinoma",
"has_exemption": false,
"start_date": "2021-12-06",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04573023",
"publication_url": "https://clinicaltrials.gov/study/NCT04573023",
"title": "A Phase III Study of JR-141 in Patients With Mucopolysaccharidosis II (STARLIGHT)",
"has_exemption": false,
"start_date": "2022-02-14",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "JCR Pharmaceuticals Co., Ltd.",
"sponsor_slug": "jcr-pharmaceuticals-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04566991",
"publication_url": "https://clinicaltrials.gov/study/NCT04566991",
"title": "Deferoxamine In the Treatment of Aneurysmal Subarachnoid Hemorrhage (DISH)",
"has_exemption": false,
"start_date": "2022-03-20",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Aditya S. Pandey, MD",
"sponsor_slug": "aditya-s-pandey-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04898010",
"publication_url": "https://clinicaltrials.gov/study/NCT04898010",
"title": "Investigator Initiated Pilot Study to Assess the Safety and Efficacy of a Selective Cytopheretic Device (SCD) to Treat ICU Patients With Acute Kidney Injury (AKI) and Hepatorenal Syndrome (HRS) Type I",
"has_exemption": false,
"start_date": "2022-06-09",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Lenar Yessayan",
"sponsor_slug": "lenar-yessayan",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04741646",
"publication_url": "https://clinicaltrials.gov/study/NCT04741646",
"title": "Phosphate Binder Therapy and Chronic Kidney Disease in Children",
"has_exemption": false,
"start_date": "2022-06-17",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Los Angeles",
"sponsor_slug": "university-of-california-los-angeles",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05312671",
"publication_url": "https://clinicaltrials.gov/study/NCT05312671",
"title": "Atezolizumab With Platinum and Etoposide Chemotherapy Followed by Cystectomy for Patients With Localized Small Cell Neuroendocrine Bladder Cancer",
"has_exemption": false,
"start_date": "2022-06-27",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
"sponsor_slug": "sidney-kimmel-comprehensive-cancer-center-at-johns-hopkins",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05301816",
"publication_url": "https://clinicaltrials.gov/study/NCT05301816",
"title": "A Post-Market, Multicenter, Prospective, Global Clinical Study to Evaluate the Real-world Experience of Spinal Cord Stimulation That Includes 10 kHz in the Management of Chronic Intractable Pain Associated With Diabetic Neuropathy.",
"has_exemption": false,
"start_date": "2022-07-05",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Nevro Corp",
"sponsor_slug": "nevro-corp",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05296798",
"publication_url": "https://clinicaltrials.gov/study/NCT05296798",
"title": "A Phase III, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Giredestrant in Combination With Phesgo Versus Phesgo After Induction Therapy With Phesgo + Taxane in Patients With Previously Untreated HER2-Positive, Estrogen Receptor-Positive Locally-Advanced or Metastatic Breast Cancer",
"has_exemption": false,
"start_date": "2022-07-18",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05384535",
"publication_url": "https://clinicaltrials.gov/study/NCT05384535",
"title": "Utility of Biparametric MRI (Magnetic Resonance Imaging) as a Screening Tool for Prostate Cancer in a High-Risk Cohort",
"has_exemption": false,
"start_date": "2022-08-15",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwell Health",
"sponsor_slug": "northwell-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05570253",
"publication_url": "https://clinicaltrials.gov/study/NCT05570253",
"title": "\"A Phase 2, Double Blinded, Randomized Controlled Trial of Evexomostat (SDX-7320) or Placebo in Combination With Eribulin for Patients With Metastatic Triple-Negative Breast Cancer and Metabolic Dysfunction: The ARETHA Study",
"has_exemption": false,
"start_date": "2022-10-03",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05514054",
"publication_url": "https://clinicaltrials.gov/study/NCT05514054",
"title": "EMBER-4: A Randomized, Open-Label, Phase 3 Study of Adjuvant Imlunestrant vs Standard Adjuvant Endocrine Therapy in Patients Who Have Previously Received 2 to 5 Years of Adjuvant Endocrine Therapy for ER+, HER2- Early Breast Cancer With an Increased Risk of Recurrence",
"has_exemption": false,
"start_date": "2022-10-04",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05317806",
"publication_url": "https://clinicaltrials.gov/study/NCT05317806",
"title": "Use of Metformin in Prevention and Treatment of Cardiac Fibrosis in PAI-1 Deficient Population",
"has_exemption": false,
"start_date": "2022-10-10",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana Hemophilia &Thrombosis Center, Inc.",
"sponsor_slug": "indiana-hemophilia-thrombosis-center-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05556512",
"publication_url": "https://clinicaltrials.gov/study/NCT05556512",
"title": "A Phase 3, Randomized, Double-blind, Placebo-Controlled Study to Investigate the Effect of Tirzepatide on the Reduction of Morbidity and Mortality in Adults With Obesity",
"has_exemption": false,
"start_date": "2022-10-11",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03887481",
"publication_url": "https://clinicaltrials.gov/study/NCT03887481",
"title": "Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Aphasic AD (Logopenic Variant PPA)",
"has_exemption": false,
"start_date": "2022-10-15",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05120271",
"publication_url": "https://clinicaltrials.gov/study/NCT05120271",
"title": "A First-in-Human, Phase 1/2, Dose Escalation Study of BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors",
"has_exemption": false,
"start_date": "2022-10-26",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sotio Biotech Inc.",
"sponsor_slug": "sotio-biotech-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05256225",
"publication_url": "https://clinicaltrials.gov/study/NCT05256225",
"title": "A Phase II/III Study of Paclitaxel/Carboplatin Alone or Combined With Either Trastuzumab and Hyaluronidase-oysk (HERCEPTIN HYLECTA) or Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf (PHESGO) in HER2 Positive, Stage I-IV Endometrial Serous Carcinoma or Carcinosarcoma",
"has_exemption": false,
"start_date": "2022-11-16",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05492799",
"publication_url": "https://clinicaltrials.gov/study/NCT05492799",
"title": "Open-Label Multicenter Extension Study to Further Evaluate Safety, Tolerability and Efficacy of Intracerebroventricular AX 250 Treatment in Mucopolysaccharidosis Type IIIB (MPS IIIB, Sanfilippo Syndrome Type B) Patients",
"has_exemption": false,
"start_date": "2022-12-02",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Allievex Corporation",
"sponsor_slug": "allievex-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05650229",
"publication_url": "https://clinicaltrials.gov/study/NCT05650229",
"title": "An Interventional, Randomised, Double-blind, Parallel-group, Placebo-controlled, Flexible-dose, Adaptive Study of the Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease",
"has_exemption": false,
"start_date": "2022-12-13",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Abliva AB",
"sponsor_slug": "abliva-ab",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05640947",
"publication_url": "https://clinicaltrials.gov/study/NCT05640947",
"title": "Endoscopic Ultrasound-guided Large Diameter Lumen-apposing Metal Stent Gastro-gastrostomy for Bypass Reversal in Patients With Roux-en-y Gastric Bypass: a Proof of Concent Study",
"has_exemption": false,
"start_date": "2023-01-30",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University Hospital, Ghent",
"sponsor_slug": "university-hospital-ghent",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02616302",
"publication_url": "https://clinicaltrials.gov/study/NCT02616302",
"title": "A Phase 2, Double-Blind, 12-Week, Multicenter Study to Assess the Safety and Effectiveness of Daily Oral Administration of Dexlansoprazole Delayed-Release Capsules in Pediatric Subjects Aged 2 to 11 Years With Symptomatic Nonerosive Gastroesophageal Reflux Disease",
"has_exemption": false,
"start_date": "2023-02-20",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05644496",
"publication_url": "https://clinicaltrials.gov/study/NCT05644496",
"title": "A Randomized Controlled Trial of ZYNRELEF Versus Standard of Care for Pain Management Following Unilateral Total Knee Arthroplasty",
"has_exemption": false,
"start_date": "2023-03-09",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Baptist Health South Florida",
"sponsor_slug": "baptist-health-south-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05807399",
"publication_url": "https://clinicaltrials.gov/study/NCT05807399",
"title": "A Multiple-arm, Multiple-stage (MAMS), Phase 2B/C, Open-label, Randomized, Controlled Platform Trial to Evaluate Experimental Arms Including Optimised Use of Existing and Introduction of Novel Anti-tuberculosis Drugs, in Adults With Newly Diagnosed, Drug-sensitive, Smear-positive Pulmonary Tuberculosis",
"has_exemption": false,
"start_date": "2023-04-14",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Michael Hoelscher",
"sponsor_slug": "michael-hoelscher",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05707377",
"publication_url": "https://clinicaltrials.gov/study/NCT05707377",
"title": "A Phase 2/3, Multicenter, Randomized, Active-Controlled, Open-label Study to Evaluate the Efficacy and Safety of Zanubrutinib in Patients With Primary Membranous Nephropathy",
"has_exemption": false,
"start_date": "2023-04-17",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "BeOne Medicines",
"sponsor_slug": "beone-medicines",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02615184",
"publication_url": "https://clinicaltrials.gov/study/NCT02615184",
"title": "A Phase 2, Double-Blind, 36-Week, Multicenter Study to Assess the Safety and Effectiveness of Daily Oral Administration of Dexlansoprazole Delayed-Release Capsules for Healing of Erosive Esophagitis (EE) and Maintenance of Healed EE in Pediatric Subjects Aged 2 to 11 Years With EE",
"has_exemption": false,
"start_date": "2023-05-23",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05564598",
"publication_url": "https://clinicaltrials.gov/study/NCT05564598",
"title": "A Phase II Open-Label Randomized Study of Anti-Viral Antibiotic Therapy With and Without Familial (Maternal) Cytomegalovirus (CMV) Cytotoxic T Lymphocytes (CTLs) in Neonates With Moderate/Severe Maternal Acquired CMV Infection",
"has_exemption": false,
"start_date": "2023-07-01",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "New York Medical College",
"sponsor_slug": "new-york-medical-college",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05901675",
"publication_url": "https://clinicaltrials.gov/study/NCT05901675",
"title": "Enhancing Mobility and Psychosocial Function in Obese Veterans Following Stroke Via Weight Loss and ExeRcise (EMPOWER)",
"has_exemption": false,
"start_date": "2023-07-07",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University of South Carolina",
"sponsor_slug": "medical-university-of-south-carolina",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05514899",
"publication_url": "https://clinicaltrials.gov/study/NCT05514899",
"title": "Effects of Cannabidiol and Tetrahydrocannabinol on the Microbiome, Endocannabinoids, and Neuroinflammation in HIV",
"has_exemption": false,
"start_date": "2023-09-01",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05693909",
"publication_url": "https://clinicaltrials.gov/study/NCT05693909",
"title": "An Open-label, Dose-escalation, Dose-finding, and Proof-of-concept Trial of SP-420 in Subjects With Transfusion-dependent β-thalassemia or Low-risk Myelodysplastic Syndromes",
"has_exemption": false,
"start_date": "2023-09-04",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Pharmacosmos A/S",
"sponsor_slug": "pharmacosmos-as",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06099769",
"publication_url": "https://clinicaltrials.gov/study/NCT06099769",
"title": "A RANDOMIZED, PHASE II STUDY OF ENZALUTAMIDE, ENZALUTAMIDE WITH MIFEPRISTONE, and TREATMENT OF PHYSICIAN'S CHOICE IN PATIENTS WITH AR+ METASTATIC TRIPLE-NEGATIVE OR ER-LOW BREAST CANCER",
"has_exemption": false,
"start_date": "2023-10-18",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05836584",
"publication_url": "https://clinicaltrials.gov/study/NCT05836584",
"title": "A Randomized Phase II Study of Perioperative Atezolizumab +/- Chemotherapy in Resectable MSI-H/dMMR Gastric and Gastroesophageal Junction (GEJ) Cancer",
"has_exemption": false,
"start_date": "2023-12-06",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06244771",
"publication_url": "https://clinicaltrials.gov/study/NCT06244771",
"title": "An Open-Label, Phase 1/2 Dose Escalation, Dose Expansion and Cohort Expansion Study Evaluating the Safety, PK and Clinical Activity of FMC-376 in Participants With KRAS G12C Mutated Locally Advanced Unresectable or Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2024-02-12",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Frontier Medicines Corporation",
"sponsor_slug": "frontier-medicines-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05730712",
"publication_url": "https://clinicaltrials.gov/study/NCT05730712",
"title": "Phase II Trial of Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf (HP) Plus Enzalutamide for the Treatment of Selected Patients With Metastatic Castration-Resistant Prostate Cancer (TraPPer)",
"has_exemption": false,
"start_date": "2024-03-08",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06149481",
"publication_url": "https://clinicaltrials.gov/study/NCT06149481",
"title": "Phase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC)",
"has_exemption": false,
"start_date": "2024-03-26",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06214065",
"publication_url": "https://clinicaltrials.gov/study/NCT06214065",
"title": "Modulating Temporoparietal Junction Mentalizing-Related Activity in Autism Spectrum Disorder Using Transcranial Magnetic Stimulation",
"has_exemption": false,
"start_date": "2024-04-03",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06439277",
"publication_url": "https://clinicaltrials.gov/study/NCT06439277",
"title": "Efficacy and Safety of Tirzepatide Once Weekly Versus Placebo for the Treatment of Obesity and Weight-Related Comorbidities in Adolescents: A Randomized, Double-Blind, Placebo- Controlled Trial (SURMOUNT-ADOLESCENTS-2)",
"has_exemption": false,
"start_date": "2024-06-03",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06203600",
"publication_url": "https://clinicaltrials.gov/study/NCT06203600",
"title": "Randomized Phase II/III Trial of 2nd Line Nivolumab + Paclitaxel + Ramucirumab Versus Paclitaxel + Ramucirumab in Patients With PD-L1 CPS >/= 1 Advanced Gastric and Esophageal Adenocarcinoma (PARAMUNE)",
"has_exemption": false,
"start_date": "2024-06-24",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06470763",
"publication_url": "https://clinicaltrials.gov/study/NCT06470763",
"title": "A First-in-human, Open-label, Multicenter Phase I/II Study to Evaluate the Safety and Anti-tumor Activity of ANV600 As Single Agent and in Combination with Pembrolizumab in Participants with Advanced Solid Tumors (EXPAND-1)",
"has_exemption": false,
"start_date": "2024-07-01",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Anaveon AG",
"sponsor_slug": "anaveon-ag",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06569368",
"publication_url": "https://clinicaltrials.gov/study/NCT06569368",
"title": "A Phase II Trial Utilizing Metronidazole to Optimize the Microbiome of Rectal Adenocarcinoma Undergoing Neoadjuvant Therapy",
"has_exemption": false,
"start_date": "2024-07-10",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06736860",
"publication_url": "https://clinicaltrials.gov/study/NCT06736860",
"title": "Early and Precise Application and Evaluation of Tranexamic Acid in Patients With Traumatic Bleeding Based on Dynamic Monitoring of Thromboelastography",
"has_exemption": false,
"start_date": "2024-08-01",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Nanfang Hospital, Southern Medical University",
"sponsor_slug": "nanfang-hospital-southern-medical-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06268665",
"publication_url": "https://clinicaltrials.gov/study/NCT06268665",
"title": "A Randomized Trial of Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy",
"has_exemption": false,
"start_date": "2024-08-15",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eve Rodler",
"sponsor_slug": "eve-rodler",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06179888",
"publication_url": "https://clinicaltrials.gov/study/NCT06179888",
"title": "Randomized Phase 2 Study of Iberdomide Maintenance Therapy Following Idecabtagene Vicleucel CAR-T in Multiple Myeloma Patients",
"has_exemption": false,
"start_date": "2024-08-27",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06588413",
"publication_url": "https://clinicaltrials.gov/study/NCT06588413",
"title": "Randomized, Double-Blind Study of FOND (Fosaprepitant, ONdansetron, Dexamethasone) Plus Either Olanzapine 2.5 mg Versus 5 mg for the Prevention of Chemotherapy Induced Nausea and Vomiting in Patients Receiving High-dose Melphalan Conditioning: The FONDO-LOW Study",
"has_exemption": false,
"start_date": "2024-09-17",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Augusta University",
"sponsor_slug": "augusta-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06681922",
"publication_url": "https://clinicaltrials.gov/study/NCT06681922",
"title": "A Phase I-II Study of High-Dose Post-Transplant Cyclophosphamide, Bortezomib, and Abatacept for the Prevention of Graft-Versus-Host Disease (GVHD) Following Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)",
"has_exemption": false,
"start_date": "2024-09-23",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwell Health",
"sponsor_slug": "northwell-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06529731",
"publication_url": "https://clinicaltrials.gov/study/NCT06529731",
"title": "A Phase 2 Trial of Interferon-γ (IFN-γ) in Combination With Donor Leukocyte Infusion (DLI) to Treat Relapsed Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes (MDS) After Allogeneic Hematopoietic Stem Cell Transplantation (alloSCT)",
"has_exemption": false,
"start_date": "2024-09-23",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sawa Ito, MD",
"sponsor_slug": "sawa-ito-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06458439",
"publication_url": "https://clinicaltrials.gov/study/NCT06458439",
"title": "Phase IIa Trial to Evaluate Epcoritamab Administered Before and After CAR-T Cell Therapy in Patients With Relapsed or Refractory Large B-cell Lymphomas",
"has_exemption": false,
"start_date": "2024-09-24",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Abramson Cancer Center at Penn Medicine",
"sponsor_slug": "abramson-cancer-center-at-penn-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06643312",
"publication_url": "https://clinicaltrials.gov/study/NCT06643312",
"title": "Tethered Pelvic Assist Device for Recovery of Standing After Severe SCI",
"has_exemption": false,
"start_date": "2024-10-22",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kessler Foundation",
"sponsor_slug": "kessler-foundation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06651567",
"publication_url": "https://clinicaltrials.gov/study/NCT06651567",
"title": "A Multicenter, Randomized, Double-blind, Placebo-controlled, Flexible-dose Study of the Efficacy, Safety, and Tolerability of ITI-1284 in Patients With Agitation Associated With Alzheimer's Dementia",
"has_exemption": false,
"start_date": "2024-10-22",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Intra-Cellular Therapies, Inc.",
"sponsor_slug": "intra-cellular-therapies-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06483009",
"publication_url": "https://clinicaltrials.gov/study/NCT06483009",
"title": "Efficacy and Safety of Combination Therapy of Sintilimab and Chemotherapy With Cryoablation in the First-Line Treatment of Advanced Non-Squamous Non-Small Cell Lung Cancer (NSCLC)",
"has_exemption": false,
"start_date": "2024-10-31",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Shanghai Chest Hospital",
"sponsor_slug": "shanghai-chest-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06637501",
"publication_url": "https://clinicaltrials.gov/study/NCT06637501",
"title": "A Multicenter, Open-Label, Phase 2 Study to Investigate the Efficacy and Safety of Sonrotoclax Combined With Zanubrutinib Compared With Zanubrutinib Monotherapy in Adult Patients With Previously Untreated Chronic Lymphocytic Leukemia",
"has_exemption": false,
"start_date": "2024-11-14",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "BeOne Medicines",
"sponsor_slug": "beone-medicines",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06690775",
"publication_url": "https://clinicaltrials.gov/study/NCT06690775",
"title": "Catalina-2: A Phase 2 Study Evaluating the Efficacy and Safety of TORL-1-23 in Women With Advanced Platinum-Resistant Epithelial Ovarian Cancer (Including Primary Peritoneal and Fallopian Tube Cancers) Expressing Claudin 6",
"has_exemption": false,
"start_date": "2024-11-20",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "TORL Biotherapeutics, LLC",
"sponsor_slug": "torl-biotherapeutics-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06634069",
"publication_url": "https://clinicaltrials.gov/study/NCT06634069",
"title": "A Pilot, Randomized, Double-Blinded, Controlled Study of Hemodynamic and Acid Base Effects of 0.5M Sodium Lactate and 3% Saline Solutions in Septic Shock Patients",
"has_exemption": false,
"start_date": "2024-11-24",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University Hospital Pilsen",
"sponsor_slug": "university-hospital-pilsen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06609889",
"publication_url": "https://clinicaltrials.gov/study/NCT06609889",
"title": "A Phase 1/2 Open Label Study to Evaluate the Safety and Efficacy of Intrathecally Administered ION283 in Patients With Lafora Disease",
"has_exemption": false,
"start_date": "2024-12-03",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Berge Minassian",
"sponsor_slug": "berge-minassian",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06568783",
"publication_url": "https://clinicaltrials.gov/study/NCT06568783",
"title": "Evaluation of Patients With Refractory Dermatomyositis Using [18F]- Fibroblast Activation Protein Inhibitor-74 (FAPI-74) PET/MRI Imaging",
"has_exemption": false,
"start_date": "2024-12-31",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Farshad Moradi",
"sponsor_slug": "farshad-moradi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06192615",
"publication_url": "https://clinicaltrials.gov/study/NCT06192615",
"title": "Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)",
"has_exemption": false,
"start_date": "2025-01-06",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06782555",
"publication_url": "https://clinicaltrials.gov/study/NCT06782555",
"title": "A Phase 1/2 Immunotherapy Study of Evofosfamide in Combination with Zalifrelimab and Balstilimab in Patients with Advanced Solid Malignancies",
"has_exemption": false,
"start_date": "2025-01-08",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ImmunoGenesis",
"sponsor_slug": "immunogenesis",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06721572",
"publication_url": "https://clinicaltrials.gov/study/NCT06721572",
"title": "Role of Home-Based Transcutaneous Electrical Acustimulation for Treatment of Pain in Patients With Chronic Pancreatitis (TEA-CuP): A Double-Blind, Sham-Controlled Crossover Trial",
"has_exemption": false,
"start_date": "2025-01-13",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan",
"sponsor_slug": "university-of-michigan",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06555003",
"publication_url": "https://clinicaltrials.gov/study/NCT06555003",
"title": "Comparative Analysis of the Efficacy of Irinotecan-loaded Drug-eluting Beads (DEBIRI) in Combination With Systemic Chemotherapy Versus Chemotherapy Alone in Unresectable Colorectal Cancer Liver Metastases: a Randomized Clinical Trial",
"has_exemption": false,
"start_date": "2025-01-20",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Tehran University of Medical Sciences",
"sponsor_slug": "tehran-university-of-medical-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06435156",
"publication_url": "https://clinicaltrials.gov/study/NCT06435156",
"title": "A Phase 2 Double-blind Randomised Controlled Trial Studying the Effect of Sotagliflozin Versus Placebo in Individuals With Heart Failure and Type 1 Diabetes.",
"has_exemption": false,
"start_date": "2025-01-28",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Dundee",
"sponsor_slug": "university-of-dundee",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06689085",
"publication_url": "https://clinicaltrials.gov/study/NCT06689085",
"title": "Open-Label, Multiple-Dose, 52-Week Study to Evaluate the Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Deficiency or Absence of Endogenous Testosterone Due to Primary or Secondary Hypogonadism",
"has_exemption": false,
"start_date": "2025-02-05",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Halozyme Therapeutics",
"sponsor_slug": "halozyme-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06630845",
"publication_url": "https://clinicaltrials.gov/study/NCT06630845",
"title": "Comparison of Whole Body DWI to FDG PET Using PET/MRI",
"has_exemption": false,
"start_date": "2025-02-06",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06617923",
"publication_url": "https://clinicaltrials.gov/study/NCT06617923",
"title": "A Phase 2 Study of Senaparib in Combination With Temozolomide in ARID1A Mutation Associated Ovarian Cancer",
"has_exemption": false,
"start_date": "2025-02-06",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
"sponsor_slug": "sidney-kimmel-comprehensive-cancer-center-at-johns-hopkins",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06561152",
"publication_url": "https://clinicaltrials.gov/study/NCT06561152",
"title": "Tagraxofusp and Low-Intensity Chemotherapy for the Treatment of CD123-Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)",
"has_exemption": false,
"start_date": "2025-02-10",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06603662",
"publication_url": "https://clinicaltrials.gov/study/NCT06603662",
"title": "Systemic Oral Glucocorticoids for the Treatment of Acute Osteoarthritis Pain in the Emergency Department",
"has_exemption": false,
"start_date": "2025-02-24",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "WellSpan Health",
"sponsor_slug": "wellspan-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06610825",
"publication_url": "https://clinicaltrials.gov/study/NCT06610825",
"title": "A Phase II Clinical Trial to Evaluate the Efficacy and Safety of Fam-Trastuzumab Deruxtecan-Nxki (T-DXd) as a Subsequent Line of Therapy in HER2-Positive Metastatic Castration-Resistant Prostate Adenocarcinoma",
"has_exemption": false,
"start_date": "2025-03-05",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington D.C. Veterans Affairs Medical Center",
"sponsor_slug": "washington-dc-veterans-affairs-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06601296",
"publication_url": "https://clinicaltrials.gov/study/NCT06601296",
"title": "STING Agonist and Personalized Ultra-fractionated Stereotactic Adaptive Radiotherapy in Combination With Checkpoint Inhibition for Patients With Metastatic Kidney Cancer.",
"has_exemption": false,
"start_date": "2025-04-01",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06910787",
"publication_url": "https://clinicaltrials.gov/study/NCT06910787",
"title": "Outpatient Virtual Reality-Directed Treatment for Pain in Inflammatory Bowel Disease",
"has_exemption": false,
"start_date": "2025-04-29",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan",
"sponsor_slug": "university-of-michigan",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07207395",
"publication_url": "https://clinicaltrials.gov/study/NCT07207395",
"title": "A Study of Open-label Orally Administered JBI-802 Alone or in Combination With Pembrolizumab in Patients With Advanced NSCLC Tumors Harboring an STK11 Mutation",
"has_exemption": false,
"start_date": "2025-04-29",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Christ Hospital",
"sponsor_slug": "the-christ-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06963034",
"publication_url": "https://clinicaltrials.gov/study/NCT06963034",
"title": "A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of NBI-1117568 in Adults With Schizophrenia Who Warrant Inpatient Hospitalization",
"has_exemption": false,
"start_date": "2025-05-08",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Neurocrine Biosciences",
"sponsor_slug": "neurocrine-biosciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06665997",
"publication_url": "https://clinicaltrials.gov/study/NCT06665997",
"title": "Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease",
"has_exemption": false,
"start_date": "2025-06-26",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06935591",
"publication_url": "https://clinicaltrials.gov/study/NCT06935591",
"title": "Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study",
"has_exemption": false,
"start_date": "2025-06-27",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vektor Medical",
"sponsor_slug": "vektor-medical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04231708",
"publication_url": "https://clinicaltrials.gov/study/NCT04231708",
"title": "Effects of Pharmacological Stress and Repetitive Transcranial Magnetic Stimulation Interventions on Executive Function in Opioid Use Disorder",
"has_exemption": false,
"start_date": "2025-06-30",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Wayne State University",
"sponsor_slug": "wayne-state-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06904235",
"publication_url": "https://clinicaltrials.gov/study/NCT06904235",
"title": "A Multicentre, Multinational, Pharmacokinetic, Safety, and Efficacy Study With IV NEPA (Fosnetupitant/Palonosetron) for the Prevention of Chemotherapy-induced Nausea and Vomiting in Paediatric Cancer Patients Undergoing Highly Emetogenic Chemotherapy (HEC). A 2-part Study With Phase 2, Open-label, Randomised, Single-dose IV NEPA vs Fosaprepitant/Ondansetron in Single-day HEC and Repeated-dose IV NEPA in Multi-day HEC (Part I, Single Cycle) and With Phase 3, Double-blind, Randomised, Repeated-dose IV NEPA vs Fosaprepitant/Ondansetron in Multi-day HEC (Part II, Repeated Cycles)",
"has_exemption": false,
"start_date": "2025-07-07",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Helsinn Healthcare SA",
"sponsor_slug": "helsinn-healthcare-sa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06692686",
"publication_url": "https://clinicaltrials.gov/study/NCT06692686",
"title": "The Development of Patient-Centered Clinical AFO Prescription Guidelines to Optimize Post-Stroke Function and Quality of Life",
"has_exemption": false,
"start_date": "2025-07-08",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas at Austin",
"sponsor_slug": "university-of-texas-at-austin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07018713",
"publication_url": "https://clinicaltrials.gov/study/NCT07018713",
"title": "A Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter, Clinical Trial With Extension Period to Evaluate the Efficacy and Safety of Xeomin® Injections for the Prevention of Chronic Migraine",
"has_exemption": false,
"start_date": "2025-08-21",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Merz Therapeutics GmbH",
"sponsor_slug": "merz-therapeutics-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07096843",
"publication_url": "https://clinicaltrials.gov/study/NCT07096843",
"title": "A Phase 2, Open-Label Study to Evaluate the Safety and Efficacy of Budoprutug (TNT119) in Subjects With Primary Membranous Nephropathy (PMN)",
"has_exemption": false,
"start_date": "2025-08-25",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Climb Bio, Inc.",
"sponsor_slug": "climb-bio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06923488",
"publication_url": "https://clinicaltrials.gov/study/NCT06923488",
"title": "Phase I/II Study of Leflunomide in Combination With Decitabine for Treatment of Relapsed or Refractory (R/R) Myelodysplastic Syndromes (MDS)",
"has_exemption": false,
"start_date": "2025-08-31",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "West Virginia University",
"sponsor_slug": "west-virginia-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06565390",
"publication_url": "https://clinicaltrials.gov/study/NCT06565390",
"title": "Remote Oximeter Monitoring Post-discharge to Reduce Emergency Room Visits and Rehospitalization (ROMPER): A Randomized Clinical Trial",
"has_exemption": false,
"start_date": "2025-09-11",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07052929",
"publication_url": "https://clinicaltrials.gov/study/NCT07052929",
"title": "A Phase 1/2, Multicenter, Open-label, Dose Escalation and Expansion Clinical Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of ASP2957 in Male Participants With Invasive Ventilator-dependent X-linked Myotubular Myopathy",
"has_exemption": false,
"start_date": "2025-09-11",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Astellas Gene Therapies",
"sponsor_slug": "astellas-gene-therapies",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07224451",
"publication_url": "https://clinicaltrials.gov/study/NCT07224451",
"title": "Liquid Biopsy Following Blood-Brain Barrier Disruption Using Barrier Disrupting Fields in Patients Undergoing Spine Surgery",
"has_exemption": false,
"start_date": "2025-10-16",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sheba Medical Center",
"sponsor_slug": "sheba-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07220967",
"publication_url": "https://clinicaltrials.gov/study/NCT07220967",
"title": "A Randomized Controlled Trial to Determine the Efficacy of Local Antibiotic Delivery in the Prevention of Breast Tissue Expander-Associated Infections",
"has_exemption": false,
"start_date": "2025-10-21",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07226297",
"publication_url": "https://clinicaltrials.gov/study/NCT07226297",
"title": "An Open-label Single Center, Single Participant Study of an Experimental Antisense Oligonucleotide Treatment for Charcot-Marie-Tooth Type 2D Due to GARS1 Genetic Mutation",
"has_exemption": false,
"start_date": "2025-10-27",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "n-Lorem Foundation",
"sponsor_slug": "n-lorem-foundation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06712433",
"publication_url": "https://clinicaltrials.gov/study/NCT06712433",
"title": "Bacterial Decolonization Plus Intraoperative Indocyanine Green Angiography for Soft Tissue Sarcomas of the Lower Extremity Receiving Preoperative Radiotherapy (CONCERTO)",
"has_exemption": false,
"start_date": "2025-10-31",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Adam Olson",
"sponsor_slug": "adam-olson",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06675435",
"publication_url": "https://clinicaltrials.gov/study/NCT06675435",
"title": "The Effect of Inhaled Nitric Oxide on Intrapulmonary Shunt in Acutely Hypoxemic Patients With Severe Obesity",
"has_exemption": false,
"start_date": "2025-10-31",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06861088",
"publication_url": "https://clinicaltrials.gov/study/NCT06861088",
"title": "A Randomized, Placebo-Controlled, Double-Blind Phase 3 Trial Comparing, Relative to Placebo, the Effect of Kinisoquin on Thromboembolic Events in Patients With Metastatic Pancreatic Cancer (CATIQ P3)",
"has_exemption": false,
"start_date": "2025-10-31",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Quercis Pharma AG",
"sponsor_slug": "quercis-pharma-ag",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06990945",
"publication_url": "https://clinicaltrials.gov/study/NCT06990945",
"title": "Clinical Performance And Radiographic Assessment Of Mesoporous Bioactive Glass Adhesive Vs. Universal Adhesive In Class II Carious Lesions",
"has_exemption": false,
"start_date": "2025-10-31",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Cairo University",
"sponsor_slug": "cairo-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07111988",
"publication_url": "https://clinicaltrials.gov/study/NCT07111988",
"title": "Valbenazine in Obsessive-compulsive Disorder: A Randomized Double-blind Placebo-controlled Crossover Trial",
"has_exemption": false,
"start_date": "2025-10-31",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07114718",
"publication_url": "https://clinicaltrials.gov/study/NCT07114718",
"title": "Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study",
"has_exemption": false,
"start_date": "2025-10-31",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Starlight Cardiovascular Inc",
"sponsor_slug": "starlight-cardiovascular-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07135687",
"publication_url": "https://clinicaltrials.gov/study/NCT07135687",
"title": "Oral Losartan to Decrease the Risk of Postoperative Arthrofibrosis Following Primary and Revision Anterior Cruciate Ligament Reconstruction",
"has_exemption": false,
"start_date": "2025-10-31",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Rush University Medical Center",
"sponsor_slug": "rush-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07197788",
"publication_url": "https://clinicaltrials.gov/study/NCT07197788",
"title": "Endogenex Access Study",
"has_exemption": false,
"start_date": "2025-10-31",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Endogenex, Inc.",
"sponsor_slug": "endogenex-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07174687",
"publication_url": "https://clinicaltrials.gov/study/NCT07174687",
"title": "Efficacy of Dapagliflozin in the Progression of Geographic Atrophy Secondary to Age-Related Macular Degeneration",
"has_exemption": false,
"start_date": "2025-10-31",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07167693",
"publication_url": "https://clinicaltrials.gov/study/NCT07167693",
"title": "Phase 1 Randomized Clinical Trial of Arginine Hydrochloride Administration to Reduce Duration of Diabetic Ketoacidosis in Patients With Type 2 Diabetes",
"has_exemption": false,
"start_date": "2025-11-01",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "David K Carroll",
"sponsor_slug": "david-k-carroll",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07202273",
"publication_url": "https://clinicaltrials.gov/study/NCT07202273",
"title": "A Feasibility Study of Simulation-Free, Single-Fraction Palliative Radiation Therapy for Treatment of Bone Metastases (SIM-FREE RT)",
"has_exemption": false,
"start_date": "2025-11-03",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Utah",
"sponsor_slug": "university-of-utah",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07220876",
"publication_url": "https://clinicaltrials.gov/study/NCT07220876",
"title": "A Prospective, Multicenter, Single-Arm, Open-Label Clinical Trial of the Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma",
"has_exemption": false,
"start_date": "2025-11-03",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Avisi Technologies Inc.",
"sponsor_slug": "avisi-technologies-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07222072",
"publication_url": "https://clinicaltrials.gov/study/NCT07222072",
"title": "Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study",
"has_exemption": false,
"start_date": "2025-11-03",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Cleveland Clinic",
"sponsor_slug": "the-cleveland-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07092566",
"publication_url": "https://clinicaltrials.gov/study/NCT07092566",
"title": "Efficacy of Ropivacaine Epinephrine Clonidine Ketorolac (R.E.C.K) vs Exparel in Robotic Nephrectomy: a Randomized, Prospective Trial",
"has_exemption": false,
"start_date": "2025-11-14",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07201402",
"publication_url": "https://clinicaltrials.gov/study/NCT07201402",
"title": "Prospective Long-term Study of Etonogestrel Contraceptive Implant Insertion at an Alternative Scapular Site",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07249372",
"publication_url": "https://clinicaltrials.gov/study/NCT07249372",
"title": "A Phase 2 Study of DRP-104, a Glutamine Antagonist, in Patients With NFE2L2/KEAP1-altered Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07096726",
"publication_url": "https://clinicaltrials.gov/study/NCT07096726",
"title": "Boston Medical Center Ultrasound Decongestion Study",
"has_exemption": false,
"start_date": "2025-12-31",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Boston Medical Center",
"sponsor_slug": "boston-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07209462",
"publication_url": "https://clinicaltrials.gov/study/NCT07209462",
"title": "Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of MRM-3379 in Male Participants With Fragile X Syndrome",
"has_exemption": false,
"start_date": "2025-12-31",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mirum Pharmaceuticals, Inc.",
"sponsor_slug": "mirum-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07218952",
"publication_url": "https://clinicaltrials.gov/study/NCT07218952",
"title": "Ultra-low Dose, DaT-SPECT-guided Radiation Therapy for the Treatment of Parkinson's Disease",
"has_exemption": false,
"start_date": "2025-12-31",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04266275",
"publication_url": "https://clinicaltrials.gov/study/NCT04266275",
"title": "An Investigation in the Use of Curcumin Topical Herbal Agent for the Treatment of Cervical Intraepithelial Neoplasia",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Lisa Flowers",
"sponsor_slug": "lisa-flowers",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06226662",
"publication_url": "https://clinicaltrials.gov/study/NCT06226662",
"title": "A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of NM8074 in Patients with Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis (AAV)",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NovelMed Therapeutics",
"sponsor_slug": "novelmed-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06299644",
"publication_url": "https://clinicaltrials.gov/study/NCT06299644",
"title": "Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss Using the Endomina Plicating Device: A Randomized Trial",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2027-10-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03987386",
"publication_url": "https://clinicaltrials.gov/study/NCT03987386",
"title": "Post Operative External Beam Radiotherapy for Prostate Cancer: Randomized Trial Comparing Standard vs. Hypofractionated Radiation Therapy (PORT-HYFX)",
"has_exemption": false,
"start_date": "2019-05-30",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04862663",
"publication_url": "https://clinicaltrials.gov/study/NCT04862663",
"title": "A Phase Ib/III, Open-label, Randomised Study of Capivasertib Plus CDK4/6 Inhibitors and Fulvestrant Versus CDK4/6 Inhibitors and Fulvestrant in Hormone Receptor-Positive and Human Epidermal Growth Factor Receptor 2-Negative Locally Advanced, Unresectable or Metastatic Breast Cancer (CAPItello-292)",
"has_exemption": false,
"start_date": "2021-05-10",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05628779",
"publication_url": "https://clinicaltrials.gov/study/NCT05628779",
"title": "Evaluation of the Safety, Efficacy and Cost-effectiveness of Transcatheter Tricuspid Valve Repair in Patients With Severe Tricuspid Regurgitation in the Netherlands.",
"has_exemption": false,
"start_date": "2022-12-12",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "St. Antonius Hospital",
"sponsor_slug": "st-antonius-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05687266",
"publication_url": "https://clinicaltrials.gov/study/NCT05687266",
"title": "A Phase III, Randomised, Open-label, Multicentre, Global Study of Datopotamab Deruxtecan (Dato-DXd) in Combination With Durvalumab and Carboplatin Versus Pembrolizumab in Combination With Platinum-based Chemotherapy for the First-line Treatment of Patients With Locally Advanced or Metastatic NSCLC Without Actionable Genomic Alterations (D926NC00001; AVANZAR)",
"has_exemption": false,
"start_date": "2022-12-29",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05723588",
"publication_url": "https://clinicaltrials.gov/study/NCT05723588",
"title": "Neuroimaging Correlates and Feasibility of Transcranial Magnetic Stimulation (TMS) to Improve Smoking Cessation Outcomes in Veterans With Comorbid PTSD",
"has_exemption": false,
"start_date": "2023-10-31",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06161532",
"publication_url": "https://clinicaltrials.gov/study/NCT06161532",
"title": "A Phase II Study of Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as High Grade Neuroendocrine Carcinomas, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile Cancer",
"has_exemption": false,
"start_date": "2024-08-01",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06465953",
"publication_url": "https://clinicaltrials.gov/study/NCT06465953",
"title": "A Phase 3, Multicenter, Open Label, Randomized, Non-comparative Two-arm Study of Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Adult Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an Isocitrate Dehydrogenase-1 (IDH1) Mutation (PyramIDH Study)",
"has_exemption": false,
"start_date": "2024-12-03",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Institut de Recherches Internationales Servier",
"sponsor_slug": "institut-de-recherches-internationales-servier",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06706921",
"publication_url": "https://clinicaltrials.gov/study/NCT06706921",
"title": "Usefulness of Tumor Heterogeneity Assessment in Patients With MCRPC Undergoing Radioligand Therapy With 177LU-PSMA-617 Using Serial 18F-DCFPYL, 18F-FDG and 18F-Fluciclovine PET/CT Predicting Clinical Outcome",
"has_exemption": false,
"start_date": "2024-12-15",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Greater Los Angeles Healthcare System",
"sponsor_slug": "va-greater-los-angeles-healthcare-system",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06455527",
"publication_url": "https://clinicaltrials.gov/study/NCT06455527",
"title": "HRV-Guided tDCS: Integrating A Biomarker For Clinical Utility",
"has_exemption": false,
"start_date": "2025-01-02",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06357676",
"publication_url": "https://clinicaltrials.gov/study/NCT06357676",
"title": "A Phase Ib/II Study Evaluating the Clinical Activity of Glofitamab Plus Ibrutinib (GLIB) With Obinutuzumab Pretreatment in Previously Untreated Mantle Cell Lymphoma in Patients ≥ 65 or Ages 18-64 With High-Risk Features",
"has_exemption": false,
"start_date": "2025-05-09",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "OHSU Knight Cancer Institute",
"sponsor_slug": "ohsu-knight-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06807437",
"publication_url": "https://clinicaltrials.gov/study/NCT06807437",
"title": "A Randomized Phase III Blinded Trial of Lanreotide for the Prevention of Postoperative Pancreatic Fistula",
"has_exemption": false,
"start_date": "2025-05-09",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "SWOG Cancer Research Network",
"sponsor_slug": "swog-cancer-research-network",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07017322",
"publication_url": "https://clinicaltrials.gov/study/NCT07017322",
"title": "Investigating Non-invasive Cranial Electrotherapy Stimulation for Acute Anxiety in Inpatients With Eating Disorders",
"has_exemption": false,
"start_date": "2025-06-03",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Rogers Behavioral Health",
"sponsor_slug": "rogers-behavioral-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07217912",
"publication_url": "https://clinicaltrials.gov/study/NCT07217912",
"title": "Randomized, Double-blind Trial of Daridorexant to Prevent Delirium After Heart Surgery",
"has_exemption": false,
"start_date": "2025-10-20",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Rochester",
"sponsor_slug": "university-of-rochester",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07115056",
"publication_url": "https://clinicaltrials.gov/study/NCT07115056",
"title": "Extended Post-Operative Oral Tranexamic Acid Dosing After ACL Reconstruction: A Multicenter Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2025-11-01",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Campbell Clinic",
"sponsor_slug": "campbell-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07191860",
"publication_url": "https://clinicaltrials.gov/study/NCT07191860",
"title": "A Randomized, Controlled, Multi-Center, Prospective Trial of Paclitaxel-Coated Pulmonary Balloon for the Treatment of Benign Airway Stenosis (OXYGEN-RCT Trial)",
"has_exemption": false,
"start_date": "2025-11-01",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Airiver Medical, Inc.",
"sponsor_slug": "airiver-medical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07216872",
"publication_url": "https://clinicaltrials.gov/study/NCT07216872",
"title": "A Prospective, Double Blind, Randomized, Controlled Study to Evaluate the Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment of Alcohol Use Disorder (AUD)",
"has_exemption": false,
"start_date": "2025-11-07",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Brainsway",
"sponsor_slug": "brainsway",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07059611",
"publication_url": "https://clinicaltrials.gov/study/NCT07059611",
"title": "Phase II Study of Neoadjuvant RP2 in Combination With Preoperative Flot for Patients With Stage II or Higher, Non-metastatic Gastroesophageal Adenocarcinoma",
"has_exemption": false,
"start_date": "2025-11-08",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Abramson Cancer Center at Penn Medicine",
"sponsor_slug": "abramson-cancer-center-at-penn-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07226700",
"publication_url": "https://clinicaltrials.gov/study/NCT07226700",
"title": "A Randomized, Placebo-controlled, Double-blind Trial of Suzetrigine in Total Hip Arthroplasty",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Hospital for Special Surgery, New York",
"sponsor_slug": "hospital-for-special-surgery-new-york",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07220226",
"publication_url": "https://clinicaltrials.gov/study/NCT07220226",
"title": "Venous Function and the Effect of Venous Compression on Exercise Cardiovascular Function in Patients With Fontan Circulation.",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2027-11-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03595683",
"publication_url": "https://clinicaltrials.gov/study/NCT03595683",
"title": "Phase II Dual-Cohort Study Evaluating the Effects of Pembrolizumab in the Presence of Gut Microbiota Modulation With EDP1503 in Advanced Melanoma Naïve or Refractory to Anti-PD1 Antibody",
"has_exemption": false,
"start_date": "2018-10-02",
"completion_date": "2027-11-02",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06750289",
"publication_url": "https://clinicaltrials.gov/study/NCT06750289",
"title": "BRISOTE: A Multicentre, Randomised, Double-Blind, Parallel Group, Active-Controlled, Phase 3b Study to Evaluate the Efficacy and Safety of Benralizumab 30 mg SC in Eosinophilic Asthma Patients Uncontrolled on Medium-Dose Inhaled Corticosteroid Plus Long-acting β2-Agonist.",
"has_exemption": false,
"start_date": "2025-03-28",
"completion_date": "2027-11-02",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07044336",
"publication_url": "https://clinicaltrials.gov/study/NCT07044336",
"title": "Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4 Selected Advanced/Metastatic Endometrial Cancer Who Progressed On or After Platinum Based Chemotherapy and Anti-PD-1/Anti-PD-L1 Therapy (Bluestar-Endometrial01)",
"has_exemption": false,
"start_date": "2025-08-01",
"completion_date": "2027-11-02",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227415",
"publication_url": "https://clinicaltrials.gov/study/NCT07227415",
"title": "AN INTERVENTIONAL PHASE 1B/2 STUDY TO EVALUATE THE SAFETY AND EFFICACY OF PF-08634404 MONOTHERAPY AND IN COMBINATION WITH OTHER ANTICANCER AGENTS IN ADULT PARTICIPANTS WITH LOCALLY ADVANCED OR METASTATIC RENAL CELL CARCINOMA",
"has_exemption": false,
"start_date": "2025-12-04",
"completion_date": "2027-11-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04471727",
"publication_url": "https://clinicaltrials.gov/study/NCT04471727",
"title": "A Phase 1/2 Open-label, Multicenter, Dose Escalation and Dose Expansion Study of the Safety, Tolerability, and Pharmacokinetics of HPN328 Monotherapy and HPN328 With Atezolizumab or Ifinatamab Deruxtecan (I-DXd) in Patients With Advanced Cancers Associated With Expression of Delta-like Canonical Notch Ligand 3 (DLL3).",
"has_exemption": false,
"start_date": "2020-12-14",
"completion_date": "2027-11-03",
"has_results": false,
"results_due": false,
"sponsor_name": "Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)",
"sponsor_slug": "harpoon-therapeutics-inc-a-subsidiary-of-merck-co-inc-rahway-new-jersey-usa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05551793",
"publication_url": "https://clinicaltrials.gov/study/NCT05551793",
"title": "Dupilumab in the Treatment of Alopecia Areata Patients With an Atopic Background and/or High IgE",
"has_exemption": false,
"start_date": "2023-04-10",
"completion_date": "2027-11-03",
"has_results": false,
"results_due": false,
"sponsor_name": "Emma Guttman",
"sponsor_slug": "emma-guttman",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06784999",
"publication_url": "https://clinicaltrials.gov/study/NCT06784999",
"title": "Randomized Prospective Study Comparing Sufentanil Infusion vs Intravenous Methadone for Postoperative Analgesia Following Head and Neck Dissection With Free Flap or Rotational Reconstruction",
"has_exemption": false,
"start_date": "2025-01-10",
"completion_date": "2027-11-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07054515",
"publication_url": "https://clinicaltrials.gov/study/NCT07054515",
"title": "18-month Double-blind, Randomized, Placebo-controlled, Multicenter, Phase 3 Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease and in Late-infantile and Juvenile-onset Forms of GM1 Gangliosidosis or GM2 Gangliosidosis",
"has_exemption": false,
"start_date": "2025-06-30",
"completion_date": "2027-11-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Azafaros A.G.",
"sponsor_slug": "azafaros-ag",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07082543",
"publication_url": "https://clinicaltrials.gov/study/NCT07082543",
"title": "18-month Double-blind, Randomized, Placebo-controlled, Multicenter, Phase 3 Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease and in Late-infantile and Juvenile-onset Forms of GM1 Gangliosidosis or GM2 Gangliosidosis",
"has_exemption": false,
"start_date": "2025-06-30",
"completion_date": "2027-11-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Azafaros A.G.",
"sponsor_slug": "azafaros-ag",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07082725",
"publication_url": "https://clinicaltrials.gov/study/NCT07082725",
"title": "18-month Double-blind, Randomized, Placebo-controlled, Multicenter, Phase 3 Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease and in Late-infantile and Juvenile-onset Forms of GM1 Gangliosidosis or GM2 Gangliosidosis",
"has_exemption": false,
"start_date": "2025-06-30",
"completion_date": "2027-11-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Azafaros A.G.",
"sponsor_slug": "azafaros-ag",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06979596",
"publication_url": "https://clinicaltrials.gov/study/NCT06979596",
"title": "A Multicenter, Open-label, Phase 2 Basket Study of MK-5684 in Participants With Selected Solid Tumors (OMAHA-015)",
"has_exemption": false,
"start_date": "2025-08-11",
"completion_date": "2027-11-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06508749",
"publication_url": "https://clinicaltrials.gov/study/NCT06508749",
"title": "Phase I/II Trial to Evaluate the Impact of Three Broadly Neutralizing Antibodies or Analytic Treatment Interruption on Viral Reservoir, Immune Function, and Maintenance of HIV Suppression in Early Treated Children in Botswana",
"has_exemption": false,
"start_date": "2024-11-11",
"completion_date": "2027-11-05",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Allergy and Infectious Diseases (NIAID)",
"sponsor_slug": "national-institute-of-allergy-and-infectious-diseases-niaid",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06813911",
"publication_url": "https://clinicaltrials.gov/study/NCT06813911",
"title": "A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Atherosclerotic Cardiovascular Disease (ASCVD), and Elevated LDL-C and Lp(a)",
"has_exemption": false,
"start_date": "2025-04-30",
"completion_date": "2027-11-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06780787",
"publication_url": "https://clinicaltrials.gov/study/NCT06780787",
"title": "Phase II Clinical Trial of FOLFOX, Botensilimab, Plus Balstilimab in Patients With Localized Rectal Cancer",
"has_exemption": false,
"start_date": "2025-05-20",
"completion_date": "2027-11-05",
"has_results": false,
"results_due": false,
"sponsor_name": "City of Hope Medical Center",
"sponsor_slug": "city-of-hope-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07082738",
"publication_url": "https://clinicaltrials.gov/study/NCT07082738",
"title": "A Multicentre, Parallel-group, Phase IIb, Randomised, Double-blind, Placebo-controlled, 4-Arm, 24-Week Study to Evaluate the Efficacy and Safety of AZD6793 Tablets in Adult Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (PRESTO)",
"has_exemption": false,
"start_date": "2025-06-27",
"completion_date": "2027-11-05",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07007962",
"publication_url": "https://clinicaltrials.gov/study/NCT07007962",
"title": "A Multi-center, Open-label, Single-arm Study to Evaluate the Efficacy and Safety of Oral Rilzabrutinib in Adults With Immune Thrombocytopenia (ITP) Who Failed First-line Treatment",
"has_exemption": false,
"start_date": "2025-10-24",
"completion_date": "2027-11-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07224035",
"publication_url": "https://clinicaltrials.gov/study/NCT07224035",
"title": "Helicobacter Pylori Screening and Treatment in the At-risk South Florida Community- AIM 1",
"has_exemption": false,
"start_date": "2022-10-15",
"completion_date": "2027-11-06",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Miami",
"sponsor_slug": "university-of-miami",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07224048",
"publication_url": "https://clinicaltrials.gov/study/NCT07224048",
"title": "Helicobacter Pylori Screening and Treatment in the At-risk South Florida Community-AIM 2",
"has_exemption": false,
"start_date": "2024-11-06",
"completion_date": "2027-11-06",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Miami",
"sponsor_slug": "university-of-miami",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03077841",
"publication_url": "https://clinicaltrials.gov/study/NCT03077841",
"title": "Optimizing Preventative Adjuvant Linac-Based Radiation: The OPAL Trial a Phase II/III Study of Hypofractionated Partial Breast Irradiation in Women With Early Stage Breast Cancer",
"has_exemption": false,
"start_date": "2017-03-06",
"completion_date": "2027-11-08",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05064878",
"publication_url": "https://clinicaltrials.gov/study/NCT05064878",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Fixed-Dose, Multicenter Study To Examine The Efficacy And Safety Of ZX008 In Subjects With CDKL5 Deficiency Disorder Followed By An Open-Label Extension",
"has_exemption": false,
"start_date": "2022-03-08",
"completion_date": "2027-11-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Zogenix, Inc.",
"sponsor_slug": "zogenix-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06323980",
"publication_url": "https://clinicaltrials.gov/study/NCT06323980",
"title": "Randomized, Prospective, Multi-Center Study of the INHANCE Stemless Total Reverse Shoulder System",
"has_exemption": false,
"start_date": "2025-03-04",
"completion_date": "2027-11-10",
"has_results": false,
"results_due": false,
"sponsor_name": "DePuy Orthopaedics",
"sponsor_slug": "depuy-orthopaedics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04879121",
"publication_url": "https://clinicaltrials.gov/study/NCT04879121",
"title": "A Phase II Basket Study of the Oral TRK Inhibitor Larotrectinib (BAY2757556) in Subjects With NTRK Amplification Positive and Pan-TRK Positive Tumors",
"has_exemption": false,
"start_date": "2021-04-30",
"completion_date": "2027-11-11",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05265169",
"publication_url": "https://clinicaltrials.gov/study/NCT05265169",
"title": "Ablation With Confirmation of Colorectal Liver Metastases (ACCLAIM) Prospective Trial for Microwave Ablation as a Local Cure",
"has_exemption": false,
"start_date": "2023-01-13",
"completion_date": "2027-11-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Society of Interventional Oncology",
"sponsor_slug": "society-of-interventional-oncology",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06885034",
"publication_url": "https://clinicaltrials.gov/study/NCT06885034",
"title": "A Phase 1b/2, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of GSK5764227 Alone and in Combination in Participants With Previously Treated Advanced Unresectable or Metastatic Gastrointestinal Solid Tumors",
"has_exemption": false,
"start_date": "2025-06-11",
"completion_date": "2027-11-11",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05133440",
"publication_url": "https://clinicaltrials.gov/study/NCT05133440",
"title": "SAXON-PC: A Phase II Randomized Trial of Stereotactic Body Radiation Therapy (SBRT) And Radium (Ra-223) Dichloride for Oligorecurrent, Non-castrate Resistant Prostate Cancer",
"has_exemption": false,
"start_date": "2021-11-12",
"completion_date": "2027-11-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06411158",
"publication_url": "https://clinicaltrials.gov/study/NCT06411158",
"title": "Training for Urinary Leakage Improvement After Pregnancy",
"has_exemption": false,
"start_date": "2024-11-12",
"completion_date": "2027-11-12",
"has_results": false,
"results_due": false,
"sponsor_name": "NICHD Pelvic Floor Disorders Network",
"sponsor_slug": "nichd-pelvic-floor-disorders-network",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06928363",
"publication_url": "https://clinicaltrials.gov/study/NCT06928363",
"title": "A First-in-human, Multicenter, Open-label Phase I/II Investigational Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of KY-0301 as Monotherapy in Patients With Advanced Solid Tumors.",
"has_exemption": false,
"start_date": "2025-05-01",
"completion_date": "2027-11-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Novatim Immune Therapeutics (Zhejiang) Co., Ltd.",
"sponsor_slug": "novatim-immune-therapeutics-zhejiang-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07220135",
"publication_url": "https://clinicaltrials.gov/study/NCT07220135",
"title": "A Randomized Trial of Neoadjuvant THP vs TCHP for HER2-amplified/Positive Breast Cancer (NeoTHERa)",
"has_exemption": false,
"start_date": "2025-11-14",
"completion_date": "2027-11-14",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Kansas Medical Center",
"sponsor_slug": "university-of-kansas-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03972657",
"publication_url": "https://clinicaltrials.gov/study/NCT03972657",
"title": "A Phase 1/2 Study of REGN5678 (Anti-PSMAxCD28) With or Without Cemiplimab (Anti-PD-1) in Patients With Metastatic Castration-Resistant Prostate Cancer and Other Tumors Associated With PSMA Expression",
"has_exemption": false,
"start_date": "2019-08-12",
"completion_date": "2027-11-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05075980",
"publication_url": "https://clinicaltrials.gov/study/NCT05075980",
"title": "HEADLIGHT: Hypofractionated Proton Therapy for Head and Neck Cancers",
"has_exemption": false,
"start_date": "2022-02-16",
"completion_date": "2027-11-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06007690",
"publication_url": "https://clinicaltrials.gov/study/NCT06007690",
"title": "A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma",
"has_exemption": false,
"start_date": "2023-12-06",
"completion_date": "2027-11-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Aura Biosciences",
"sponsor_slug": "aura-biosciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06159166",
"publication_url": "https://clinicaltrials.gov/study/NCT06159166",
"title": "A Phase 1/2a Open-label, Multicenter Dose Finding Study to Evaluate the Safety and Anti-tumor Activity of Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF).",
"has_exemption": false,
"start_date": "2024-02-12",
"completion_date": "2027-11-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06602453",
"publication_url": "https://clinicaltrials.gov/study/NCT06602453",
"title": "A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury and Major Adverse Kidney Events",
"has_exemption": false,
"start_date": "2025-01-17",
"completion_date": "2027-11-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Genentech, Inc.",
"sponsor_slug": "genentech-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06952478",
"publication_url": "https://clinicaltrials.gov/study/NCT06952478",
"title": "A Double-Blind, Randomized, Active-Controlled, Parallel-group, Phase 1/3 Study to Compare Pharmacokinetics, Efficacy and Safety of Subcutaneous CT-P44 and Darzalex Faspro in Combination With Lenalidomide and Dexamethasone in Patients With Refractory or Relapsed Multiple Myeloma",
"has_exemption": false,
"start_date": "2025-08-12",
"completion_date": "2027-11-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Celltrion",
"sponsor_slug": "celltrion",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07236437",
"publication_url": "https://clinicaltrials.gov/study/NCT07236437",
"title": "Living Well Program: Impact on Healthcare Costs and Clinical Outcomes in Breast Cancer Care",
"has_exemption": false,
"start_date": "2025-11-15",
"completion_date": "2027-11-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Scott A. Irwin, MD, PhD",
"sponsor_slug": "scott-a-irwin-md-phd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04108156",
"publication_url": "https://clinicaltrials.gov/study/NCT04108156",
"title": "A Phase III, Multicenter, Randomized, Visual Assessor-Masked, Active-comparator Study of the Efficacy, Safety, and Pharmacokinetics of the Port Delivery System With Ranibizumab in Patients With Diabetic Macular Edema (Pagoda)",
"has_exemption": true,
"start_date": "2019-09-30",
"completion_date": "2027-11-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06953583",
"publication_url": "https://clinicaltrials.gov/study/NCT06953583",
"title": "A Phase 3, 2-Part, Randomized, Double-Blind, Placebo-Controlled Study (Part 1) and Open-Label Extension (Part 2) to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Omaveloxolone (BIIB141) in Participants With Friedreich's Ataxia Aged 2 to < 16 Years",
"has_exemption": false,
"start_date": "2025-06-09",
"completion_date": "2027-11-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Biogen",
"sponsor_slug": "biogen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06991257",
"publication_url": "https://clinicaltrials.gov/study/NCT06991257",
"title": "A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF AN ORAL BRANCHED-CHAIN KETOACID DEHYDROGENASE KINASE INHIBITOR, PF-07328948, IN ADULTS WITH HEART FAILURE (BRANCH-HF)",
"has_exemption": false,
"start_date": "2025-06-19",
"completion_date": "2027-11-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07221812",
"publication_url": "https://clinicaltrials.gov/study/NCT07221812",
"title": "Continuous Glucose Monitors (CGMs) and Readmission Rates",
"has_exemption": false,
"start_date": "2025-11-18",
"completion_date": "2027-11-17",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Maryland, Baltimore",
"sponsor_slug": "university-of-maryland-baltimore",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04068649",
"publication_url": "https://clinicaltrials.gov/study/NCT04068649",
"title": "A Phase 2 Randomized Study With a Non-randomized Cohort : Assessing Single-Fraction SBRT Versus Standard Palliative Radiation in Patients With Metastatic Disease (ASTEROID)",
"has_exemption": false,
"start_date": "2019-11-18",
"completion_date": "2027-11-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Roswell Park Cancer Institute",
"sponsor_slug": "roswell-park-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03976843",
"publication_url": "https://clinicaltrials.gov/study/NCT03976843",
"title": "A Phase II Multi-Institutional Trial to Evaluate Prostate Specific Membrane Antigen (PMSA)-Based PET Imaging of High Risk Prostate Cancer",
"has_exemption": false,
"start_date": "2019-12-04",
"completion_date": "2027-11-19",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06097728",
"publication_url": "https://clinicaltrials.gov/study/NCT06097728",
"title": "A Phase III, Randomized, Open-Label, Multicenter, Global Study of Volrustomig (MEDI5752) in Combination With Carboplatin Plus Pemetrexed Versus Platinum Plus Pemetrexed or Nivolumab Plus Ipilimumab in Participants With Unresectable Pleural Mesothelioma (eVOLVE-Meso)",
"has_exemption": false,
"start_date": "2023-11-09",
"completion_date": "2027-11-19",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07225946",
"publication_url": "https://clinicaltrials.gov/study/NCT07225946",
"title": "A Phase 3 Randomized, Open-label Study of Pasritamig (JNJ-78278343), a T-cell-redirecting Agent Targeting Human Kallikrein 2, With Docetaxel Versus Docetaxel for Metastatic Castration-resistant Prostate Cancer",
"has_exemption": false,
"start_date": "2026-01-15",
"completion_date": "2027-11-19",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05497804",
"publication_url": "https://clinicaltrials.gov/study/NCT05497804",
"title": "REsponse Adapted Combination Therapy Approaches for High-Risk Multiple Myeloma (REACH)",
"has_exemption": false,
"start_date": "2022-09-22",
"completion_date": "2027-11-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06567015",
"publication_url": "https://clinicaltrials.gov/study/NCT06567015",
"title": "Phase I/II First-In-Human Open-label Trial to Assess Safety and Efficacy of STX-241 in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Resistant to EGFR Tyrosine Kinase Inhibitors (TKIs).",
"has_exemption": false,
"start_date": "2024-09-17",
"completion_date": "2027-11-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Pierre Fabre Medicament",
"sponsor_slug": "pierre-fabre-medicament",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05357092",
"publication_url": "https://clinicaltrials.gov/study/NCT05357092",
"title": "Evaluation of Presurgical Orthopedics in Patients With Cleft Lip and/or Palate, a Randomized Controlled Clinial Trial.",
"has_exemption": false,
"start_date": "2025-11-21",
"completion_date": "2027-11-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Universidad Complutense de Madrid",
"sponsor_slug": "universidad-complutense-de-madrid",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06980038",
"publication_url": "https://clinicaltrials.gov/study/NCT06980038",
"title": "A Phase 2 Window of Opportunity Trial of Neoadjuvant Agonistic Anti-CD40 Antibody CDX-1140 and Cemiplimab (REGN2810) in AJCC Stage III-IV Head and Neck Cancer Patients Prior to Surgery",
"has_exemption": false,
"start_date": "2025-11-21",
"completion_date": "2027-11-24",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07254806",
"publication_url": "https://clinicaltrials.gov/study/NCT07254806",
"title": "A Prospective, Randomized, Double-Blinded, Sham-Controlled, Multicenter Study to Evaluate the Safety and Efficacy of IDCT in Subjects With Single-Level, Symptomatic Mild to Moderate Lumbar Intervertebral Disc Degeneration",
"has_exemption": false,
"start_date": "2025-12-30",
"completion_date": "2027-11-24",
"has_results": false,
"results_due": false,
"sponsor_name": "DiscGenics, Inc.",
"sponsor_slug": "discgenics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06698796",
"publication_url": "https://clinicaltrials.gov/study/NCT06698796",
"title": "A PHASE 3, MULTI-CENTER, OPEN-LABEL EXTENSION STUDY TO INVESTIGATE THE LONG-TERM SAFETY, TOLERABILITY, AND EFFICACY OF DAZUKIBART IN PARTICIPANTS WITH IDIOPATHIC INFLAMMATORY MYOPATHIES (INCLUDING PARTICIPANTS WITH DERMATOMYOSITIS OR POLYMYOSITIS)",
"has_exemption": false,
"start_date": "2025-01-22",
"completion_date": "2027-11-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07129343",
"publication_url": "https://clinicaltrials.gov/study/NCT07129343",
"title": "A Clinical Study to Evaluate the Safety, Efficacy and Pharmacokinetics of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in the Treatment of Bleeding Episodes in Chinese Subjects Diagnosed With Von Willebrand Disease",
"has_exemption": false,
"start_date": "2025-10-12",
"completion_date": "2027-11-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03331198",
"publication_url": "https://clinicaltrials.gov/study/NCT03331198",
"title": "An Open-Label, Phase 1/2 Study of JCAR017 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (017004)",
"has_exemption": false,
"start_date": "2017-11-27",
"completion_date": "2027-11-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Juno Therapeutics, a Subsidiary of Celgene",
"sponsor_slug": "juno-therapeutics-a-subsidiary-of-celgene",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06797518",
"publication_url": "https://clinicaltrials.gov/study/NCT06797518",
"title": "A Multicenter, Single Arm, Open Label Biopsy Study to Evaluate Structural and Functional Changes in Kidneys of Adult Patients With IgA Nephropathy Receiving Iptacopan on Top of Supportive Care",
"has_exemption": false,
"start_date": "2025-02-21",
"completion_date": "2027-11-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04774393",
"publication_url": "https://clinicaltrials.gov/study/NCT04774393",
"title": "Phase 1b/2 Study of Oral Decitabine/Cedazuridine (ASTX727) and Venetoclax in Combination With the Targeted Mutant IDH1 Inhibitor Ivosidenib or the Targeted Mutant IDH2 Inhibitor Enasidenib",
"has_exemption": false,
"start_date": "2021-05-24",
"completion_date": "2027-11-29",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06084338",
"publication_url": "https://clinicaltrials.gov/study/NCT06084338",
"title": "Phase II Trial of Targeted Radiation With no Castration for Mcrpc",
"has_exemption": false,
"start_date": "2023-12-14",
"completion_date": "2027-11-29",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06541704",
"publication_url": "https://clinicaltrials.gov/study/NCT06541704",
"title": "A Multicenter, Randomized, Double-Masked, Placebo-Controlled Phase 3 Study of the Efficacy, Safety, and Tolerability of Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration",
"has_exemption": false,
"start_date": "2024-10-30",
"completion_date": "2027-11-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07089875",
"publication_url": "https://clinicaltrials.gov/study/NCT07089875",
"title": "A Phase 3, Randomized, Double-Blind, Multicenter Study to Evaluate the Efficacy and Safety of Dotinurad Compared With Allopurinol in Adult Participants With Hyperuricemia Associated With Gout",
"has_exemption": false,
"start_date": "2025-08-01",
"completion_date": "2027-11-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Crystalys Therapeutics",
"sponsor_slug": "crystalys-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT00682318",
"publication_url": "https://clinicaltrials.gov/study/NCT00682318",
"title": "Effects of Fish Oil and Red Wine on Oxidative Stress Biomarkers: a Randomized Double-blinded Trial on the Modulation of the Eicosanoid and Isoprostane Pathways in Healthy Subjects by Omega-3 Polyunsaturated Fatty Acids and Red Wine.",
"has_exemption": false,
"start_date": "2008-05-31",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Carsten Skarke, MD",
"sponsor_slug": "carsten-skarke-md",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02352883",
"publication_url": "https://clinicaltrials.gov/study/NCT02352883",
"title": "Prospective Study of Magnetic Resonance Imaging (MRI) and Multiparameter Gene Expression Assay in Ductal Carcinoma In Situ (DCIS)",
"has_exemption": false,
"start_date": "2015-03-25",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "ECOG-ACRIN Cancer Research Group",
"sponsor_slug": "ecog-acrin-cancer-research-group",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03263572",
"publication_url": "https://clinicaltrials.gov/study/NCT03263572",
"title": "Phase II Study of the Combination of Blinatumomab and Ponatinib in Patients With Philadelphia Chromosome (Ph)-Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia (ALL)",
"has_exemption": false,
"start_date": "2017-11-29",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03554083",
"publication_url": "https://clinicaltrials.gov/study/NCT03554083",
"title": "Neoadjuvant Therapy for Patients With High Risk Stage III Melanoma: A Pilot Clinical Trial",
"has_exemption": false,
"start_date": "2018-10-05",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03672539",
"publication_url": "https://clinicaltrials.gov/study/NCT03672539",
"title": "A Pilot Study of Liposomal Cytarabine and Daunorubicin (CPX-351) in Combination With Gemtuzumab Ozogamicin (GO) in Relapsed Refractory Patients With Acute Myeloid Leukemia (AML) and Post-Hypomethylating Agent (Post-HMA) Failure High-Risk Myelodysplastic Syndrome (HR-MDS)",
"has_exemption": false,
"start_date": "2018-11-07",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04151940",
"publication_url": "https://clinicaltrials.gov/study/NCT04151940",
"title": "An Interventional Study of PET/CT Changes During Chemoimmunotherapy and Radiation Therapy for Patients With Metastatic NSCLC (PET Bright)",
"has_exemption": false,
"start_date": "2019-09-26",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Washington",
"sponsor_slug": "university-of-washington",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04170283",
"publication_url": "https://clinicaltrials.gov/study/NCT04170283",
"title": "An Open-label, Multi-center, Long-term Extension Study of Zanubrutinib (BGB-3111) Regimens in Patients With B-cell Malignancies",
"has_exemption": false,
"start_date": "2020-01-16",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "BeiGene",
"sponsor_slug": "beigene",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04219254",
"publication_url": "https://clinicaltrials.gov/study/NCT04219254",
"title": "A Phase 1/2a Clinical Trial of BI-1206, a Monoclonal Antibody to CD32b (FcγRIIB), in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors Previously Treated With Anti-PD-1 or Anti-PD-L1 Antibodies (KEYNOTE-A04)",
"has_exemption": false,
"start_date": "2020-06-29",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "BioInvent International AB",
"sponsor_slug": "bioinvent-international-ab",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04759911",
"publication_url": "https://clinicaltrials.gov/study/NCT04759911",
"title": "Neoadjuvant Treatment With Selpercatinib in RET-Altered Thyroid Cancers",
"has_exemption": false,
"start_date": "2021-02-26",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04802759",
"publication_url": "https://clinicaltrials.gov/study/NCT04802759",
"title": "A Phase Ib/II, Open-Label, Multicenter, Randomized Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Breast Cancer (MORPHEUS-BREAST CANCER)",
"has_exemption": false,
"start_date": "2021-06-22",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05026866",
"publication_url": "https://clinicaltrials.gov/study/NCT05026866",
"title": "A Study of Donanemab Versus Placebo in Participants at Risk for Cognitive and Functional Decline of Alzheimer's Disease",
"has_exemption": false,
"start_date": "2021-08-27",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05176223",
"publication_url": "https://clinicaltrials.gov/study/NCT05176223",
"title": "Optimizing Outcomes of Patients With Advanced HCC Undergoing Immunotherapy Through Novel 68Ga PSMA PET Imaging",
"has_exemption": false,
"start_date": "2022-01-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05603572",
"publication_url": "https://clinicaltrials.gov/study/NCT05603572",
"title": "A Multi-center, Open-label, Phase 1/2a Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of KAT-101 in Subjects With HCC",
"has_exemption": false,
"start_date": "2022-11-01",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Primocure Pharma",
"sponsor_slug": "primocure-pharma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05278208",
"publication_url": "https://clinicaltrials.gov/study/NCT05278208",
"title": "Phase I/II Study of Lutathera in Patients With Recurrent and/or Progressive High-Grade Central Nervous System Tumors and Meningiomas That Demonstrate Uptake on DOTATATE PET",
"has_exemption": false,
"start_date": "2022-11-21",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Nationwide Children's Hospital",
"sponsor_slug": "nationwide-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05642780",
"publication_url": "https://clinicaltrials.gov/study/NCT05642780",
"title": "A Multicenter, Open-label, Phase 2, Basket Study to Evaluate the Efficacy and Safety of SKB264 in Combination With Pembrolizumab in Subjects With Selected Solid Tumors",
"has_exemption": false,
"start_date": "2023-01-17",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Klus Pharma Inc.",
"sponsor_slug": "klus-pharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05757141",
"publication_url": "https://clinicaltrials.gov/study/NCT05757141",
"title": "A Phase 1b/2 Open-label Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy Following Fosigotifator Administration in Adult and Pediatric Subjects With Vanishing White Matter Disease",
"has_exemption": false,
"start_date": "2023-03-13",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Calico Life Sciences LLC",
"sponsor_slug": "calico-life-sciences-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04858256",
"publication_url": "https://clinicaltrials.gov/study/NCT04858256",
"title": "Phase 2, Open Label, Multicenter Study of Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative Neoplasms",
"has_exemption": false,
"start_date": "2023-03-29",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan Rogel Cancer Center",
"sponsor_slug": "university-of-michigan-rogel-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06082453",
"publication_url": "https://clinicaltrials.gov/study/NCT06082453",
"title": "Modernizing Perinatal Syphilis Testing",
"has_exemption": false,
"start_date": "2023-05-02",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05735717",
"publication_url": "https://clinicaltrials.gov/study/NCT05735717",
"title": "Phase II, Open-Label, Prospective Study of T Cell Receptor Alpha/Beta Depletion (A/B TCD) Peripheral Blood Stem Cell (PBSC) Transplantation for Children and Adults With Hematological Malignancies",
"has_exemption": false,
"start_date": "2023-05-11",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Masonic Cancer Center, University of Minnesota",
"sponsor_slug": "masonic-cancer-center-university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05889273",
"publication_url": "https://clinicaltrials.gov/study/NCT05889273",
"title": "An Open-label Extension Study to Investigate Safety and Tolerability of ML-004 in Adolescents and Adults With Autism Spectrum Disorders (ASD).",
"has_exemption": false,
"start_date": "2023-06-01",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "MapLight Therapeutics",
"sponsor_slug": "maplight-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06043440",
"publication_url": "https://clinicaltrials.gov/study/NCT06043440",
"title": "Randomized Control Trial of Oxygen Therapy in Children and Adolescents With Down Syndrome and Obstructive Sleep Apnea",
"has_exemption": false,
"start_date": "2023-10-24",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05943535",
"publication_url": "https://clinicaltrials.gov/study/NCT05943535",
"title": "A Randomized, Double-blind, Placebo-controlled, Multinational, Phase 3 Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)",
"has_exemption": false,
"start_date": "2023-10-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "United Therapeutics",
"sponsor_slug": "united-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05852717",
"publication_url": "https://clinicaltrials.gov/study/NCT05852717",
"title": "A Phase II Trial Evaluating Safety and Efficacy of Epcoritamab With Gemcitabine, Dexamethasone, and Cisplatin (GDP) Salvage Chemotherapy in Relapsed Refractory Large B-cell Lymphoma",
"has_exemption": false,
"start_date": "2023-10-31",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Dipenkumar Modi",
"sponsor_slug": "dipenkumar-modi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05849038",
"publication_url": "https://clinicaltrials.gov/study/NCT05849038",
"title": "The Role of Inflammation in Central Nervous System (CNS) Mechanisms of Anhedonia and Psychomotor Slowing in Depressed People With HIV",
"has_exemption": false,
"start_date": "2023-12-11",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06090227",
"publication_url": "https://clinicaltrials.gov/study/NCT06090227",
"title": "AMPK-activation by Metformin in FSGS: AMP-FSGS",
"has_exemption": false,
"start_date": "2023-12-14",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06123338",
"publication_url": "https://clinicaltrials.gov/study/NCT06123338",
"title": "A Single-Arm, Multicenter Phase 2 Study of Neoadjuvant Pembrolizumab With Trastuzumab and Chemotherapy in Resectable HER2+ Esophagogastric Tumors",
"has_exemption": false,
"start_date": "2024-02-01",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06046859",
"publication_url": "https://clinicaltrials.gov/study/NCT06046859",
"title": "Can Immediate Post-injury Fluoxetine Improve the Recovery Trajectories of Victims in Bodily Trauma?",
"has_exemption": false,
"start_date": "2024-03-01",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Florida",
"sponsor_slug": "university-of-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05837455",
"publication_url": "https://clinicaltrials.gov/study/NCT05837455",
"title": "NeoTAILOR: A Phase II Biomarker-directed Approach to Guide Neoadjuvant Therapy for Patients With Stage II/III ER-positive, HER2-negative Breast Cancer",
"has_exemption": false,
"start_date": "2024-05-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06285643",
"publication_url": "https://clinicaltrials.gov/study/NCT06285643",
"title": "A Phase 2, Randomized, Double-blind, Sham Surgery-controlled Study of the Efficacy and Safety of Intraputaminal AAV2-GDNF in the Treatment of Adults With Moderate Stage Parkinson's Disease",
"has_exemption": false,
"start_date": "2024-06-11",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AskBio Inc",
"sponsor_slug": "askbio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06569823",
"publication_url": "https://clinicaltrials.gov/study/NCT06569823",
"title": "A Phase 1/2 Randomized, Observer-Blinded, Active-Controlled, Dose, Escalation Multicenter Trial to Evaluate the Safety, Tolerability, and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Healthy Adult Participants 50 Years of Age and Over",
"has_exemption": false,
"start_date": "2024-06-17",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Dynavax Technologies Corporation",
"sponsor_slug": "dynavax-technologies-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06423781",
"publication_url": "https://clinicaltrials.gov/study/NCT06423781",
"title": "A Phase 2, Multicenter, Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of BHV-7000 in Treatment of Major Depressive Disorder (MDD)",
"has_exemption": false,
"start_date": "2024-08-01",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Biohaven Therapeutics Ltd.",
"sponsor_slug": "biohaven-therapeutics-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06488105",
"publication_url": "https://clinicaltrials.gov/study/NCT06488105",
"title": "Initiating Preventive Care for Hyperlipidemia in the Emergency Department: The EMERALD (Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders) Trial",
"has_exemption": false,
"start_date": "2024-08-05",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06526624",
"publication_url": "https://clinicaltrials.gov/study/NCT06526624",
"title": "ARTEMIS-009: A Phase 3, Randomized, Controlled, Multi-center, Open-label Study of HS-20093 Versus Active Surveillance As Consolidation Therapy After Chemoradiotherapy in Subjects With Limited-Stage Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2024-09-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Hansoh BioMedical R&D Company",
"sponsor_slug": "hansoh-biomedical-rd-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06160791",
"publication_url": "https://clinicaltrials.gov/study/NCT06160791",
"title": "Frontline Ruxolitinib With De-Intensified HLH-94 for Adult Hemophagocytic Lymphohistiocytosis (HLH): A Multicenter, Single-Arm Phase 2 Study",
"has_exemption": false,
"start_date": "2024-10-01",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Jerry Lee, MD, MSc, MPhil",
"sponsor_slug": "jerry-lee-md-msc-mphil",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06626139",
"publication_url": "https://clinicaltrials.gov/study/NCT06626139",
"title": "2 x 2 Factorial, Double-blind, Randomized Trial of 'Set and Setting': a Translational Study in Healthy Volunteers",
"has_exemption": false,
"start_date": "2024-10-20",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Robin Carhart-Harris, PhD, MA",
"sponsor_slug": "robin-carhart-harris-phd-ma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06413706",
"publication_url": "https://clinicaltrials.gov/study/NCT06413706",
"title": "A Randomized, Open-Label, Phase 2 Study Evaluating Abemaciclib in Combination With Temozolomide Compared to Temozolomide Monotherapy in Children and Young Adults With Newly Diagnosed High-Grade Glioma Following Radiotherapy",
"has_exemption": false,
"start_date": "2024-10-25",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06005311",
"publication_url": "https://clinicaltrials.gov/study/NCT06005311",
"title": "A Randomized Double-blind Controlled Study of the Cumulative Live Birth Rate of IVF Following Sperm Preparation by Microfluidic Chip Method Versus Density-gradient Centrifugation Method",
"has_exemption": false,
"start_date": "2024-11-01",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Professor Ernest Hung-Yu Ng",
"sponsor_slug": "professor-ernest-hung-yu-ng",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06023472",
"publication_url": "https://clinicaltrials.gov/study/NCT06023472",
"title": "A Randomized Comparison of Microfluidic Chip vs Density Gradient Centrifugation on the Euploidy Rate of Pre-implantation Genetic Testing",
"has_exemption": false,
"start_date": "2024-11-01",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Professor Ernest Hung-Yu Ng",
"sponsor_slug": "professor-ernest-hung-yu-ng",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06650202",
"publication_url": "https://clinicaltrials.gov/study/NCT06650202",
"title": "Improving Balance After Spinal Cord Injury Using a Robotic Upright Stand Trainer and Spinal Cord Epidural Stimulation",
"has_exemption": false,
"start_date": "2024-11-01",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Kessler Foundation",
"sponsor_slug": "kessler-foundation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06605118",
"publication_url": "https://clinicaltrials.gov/study/NCT06605118",
"title": "Azithromycin Prophylaxis for Prelabor Cesarean Delivery Trial",
"has_exemption": false,
"start_date": "2024-11-04",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "The George Washington University Biostatistics Center",
"sponsor_slug": "the-george-washington-university-biostatistics-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06679829",
"publication_url": "https://clinicaltrials.gov/study/NCT06679829",
"title": "Phase II Randomized Trial of Population PK Dosed Melphalan With Interleukin-6 Blockade With Siltuximab Vesrus BSA Based Melphalan in Patients With Multiple Myeloma Over Age 60 Undergoing Autologous Stem Cell Transplantation",
"has_exemption": false,
"start_date": "2024-11-06",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06660368",
"publication_url": "https://clinicaltrials.gov/study/NCT06660368",
"title": "A Prospective, Multicenter, Randomized, Open-Label, Phase II Study of Salvage BCL2i Plus CLAG-M in Relapsed or Refractory Acute Myeloid Leukemia",
"has_exemption": false,
"start_date": "2024-11-26",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06710925",
"publication_url": "https://clinicaltrials.gov/study/NCT06710925",
"title": "A Randomized, Double-blind, Placebo-controlled Phase III Study to Evaluate the Efficacy and Safety of Monoclonal Antibody TNM001 Injection Against Respiratory Syncytial Virus in High-risk Infants",
"has_exemption": false,
"start_date": "2024-11-30",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Zhuhai Trinomab Pharmaceutical Co., Ltd.",
"sponsor_slug": "zhuhai-trinomab-pharmaceutical-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06011551",
"publication_url": "https://clinicaltrials.gov/study/NCT06011551",
"title": "HYDRAFIL-D: HYDRogel Augmentation For Intervertebral Lumbar Discs",
"has_exemption": false,
"start_date": "2025-01-13",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "ReGelTec, Inc.",
"sponsor_slug": "regeltec-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06641271",
"publication_url": "https://clinicaltrials.gov/study/NCT06641271",
"title": "Vagus Nerve Stimulation to Promote Remyelination in Multiple Sclerosis",
"has_exemption": false,
"start_date": "2025-01-21",
"completion_date": "2027-11-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
}
]
}