HTTP 200 OK
Allow: GET, POST, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"recordsFiltered": 47671,
"recordsTotal": 47671,
"next": "http://fdaaa.trialstracker.net/api/trials/?format=api&length=300&ordering=-completion_date&start=46200",
"previous": "http://fdaaa.trialstracker.net/api/trials/?format=api&length=300&ordering=-completion_date&start=45600",
"results": [
{
"registry_id": "NCT06072768",
"publication_url": "https://clinicaltrials.gov/study/NCT06072768",
"title": "Using SMART Design to Develop Dynamic Treatment Regimens for Glucocorticoid Tapering",
"has_exemption": false,
"start_date": "2023-03-09",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06014255",
"publication_url": "https://clinicaltrials.gov/study/NCT06014255",
"title": "A Phase 2 Randomized Trial of Neoadjuvant Enoblituzumab Versus Standard of Care in Men With High-Risk Localized Prostate Cancer: The Help Elucidate & Attack Longitudinally (HEAT) Prostate Cancer Randomized Study",
"has_exemption": false,
"start_date": "2024-02-16",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
"sponsor_slug": "sidney-kimmel-comprehensive-cancer-center-at-johns-hopkins",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05896228",
"publication_url": "https://clinicaltrials.gov/study/NCT05896228",
"title": "Phase 2, Single-Arm Study of Iberdomide, Daratumumab, Carfilzomib, and Dexamethasone (Iber-KDd) in Patients With Relapsed/Refractory Multiple Myeloma",
"has_exemption": false,
"start_date": "2024-02-20",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Benjamin T Diamond, MD",
"sponsor_slug": "benjamin-t-diamond-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06400121",
"publication_url": "https://clinicaltrials.gov/study/NCT06400121",
"title": "Phase 2, Randomized, Double-Blind, Placebo-Controlled, Single Intravenous Dose, Parallel Efficacy Study of Apimostinel With or Without Subsequent Automated Self-Association Training in Subjects With Major Depressive Disorder",
"has_exemption": false,
"start_date": "2024-10-28",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Rebecca Price",
"sponsor_slug": "rebecca-price",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06972056",
"publication_url": "https://clinicaltrials.gov/study/NCT06972056",
"title": "A Comparative Effectiveness Study of Oral Medications Used for Migraine Prevention: The APT Comparison Study",
"has_exemption": false,
"start_date": "2025-07-09",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07038824",
"publication_url": "https://clinicaltrials.gov/study/NCT07038824",
"title": "A 2-Part, Randomized, Double-Blind, Placebo-Controlled Study in Participants With Duchenne Muscular Dystrophy Amenable to Exon 45 Skipping With an Initial Multiple Ascending Dose Part A to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ENTR-601-45, Followed by Part B to Evaluate the Safety and Efficacy of ENTR-601-45 (ELEVATE-45)",
"has_exemption": false,
"start_date": "2025-08-30",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Entrada Therapeutics, Inc.",
"sponsor_slug": "entrada-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07135895",
"publication_url": "https://clinicaltrials.gov/study/NCT07135895",
"title": "The Artix All-in-one Solution for Complete thrombEctomy With eNDovascular Approach",
"has_exemption": false,
"start_date": "2025-12-31",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Inari Medical",
"sponsor_slug": "inari-medical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07323576",
"publication_url": "https://clinicaltrials.gov/study/NCT07323576",
"title": "A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Inavolisib With Bevacizumab Plus Folfox or Folfiri as First Line Therapy in Patients With PIK3CA-Mutated Metastatic Colorectal Cancer",
"has_exemption": false,
"start_date": "2026-02-01",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06412120",
"publication_url": "https://clinicaltrials.gov/study/NCT06412120",
"title": "Single-Arm, Prospective, Multicenter Study Evaluating Safety, Tolerability, and Metabolism of Niraparib as Maintenance Following Front-Line Treatment for Ovarian Cancer in Women of African Ancestry",
"has_exemption": false,
"start_date": "2026-03-01",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Miami",
"sponsor_slug": "university-of-miami",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06941415",
"publication_url": "https://clinicaltrials.gov/study/NCT06941415",
"title": "Bumetanide vs. Furosemide for Adults Hospitalized With Cirrhosis: the BUFF Trial",
"has_exemption": false,
"start_date": "2026-03-01",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Stacy Johnson",
"sponsor_slug": "stacy-johnson",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07226713",
"publication_url": "https://clinicaltrials.gov/study/NCT07226713",
"title": "A Single-Arm, Open-label, Phase II Study Evaluating Pacritinib in Participants With Metastatic Castrate-Resistant Prostate Cancer That Progressed on or After Prior Treatment With Androgen Receptor Signaling Inhibitors - (POSTPONE)",
"has_exemption": false,
"start_date": "2026-03-01",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07187011",
"publication_url": "https://clinicaltrials.gov/study/NCT07187011",
"title": "Phase 2a Trial: Efficacy and Safety of PT150 in the Treatment of US Veterans With Posttraumatic Stress Disorder (PTSD)",
"has_exemption": false,
"start_date": "2026-04-01",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "San Diego Veterans Healthcare System",
"sponsor_slug": "san-diego-veterans-healthcare-system",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07016321",
"publication_url": "https://clinicaltrials.gov/study/NCT07016321",
"title": "Emetine for Viral Outbreaks: A Phase 2/3 Randomized, Double-Blinded, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Emetine for Dengue Fever (a.k.a. EVOLVE Antiviral Initiative)",
"has_exemption": false,
"start_date": "2026-05-01",
"completion_date": "2029-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07042919",
"publication_url": "https://clinicaltrials.gov/study/NCT07042919",
"title": "A Phase Ib/II Study of Zanzalintinib in Second Line and Beyond for the Treatment of Advanced Hepatocellular Carcinoma",
"has_exemption": false,
"start_date": "2026-03-04",
"completion_date": "2029-03-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06112418",
"publication_url": "https://clinicaltrials.gov/study/NCT06112418",
"title": "A Randomized Comparison of Cleerly Coronary Artery Disease Stage-Based Care Versus Risk Factor-Based Care for Primary Prevention of Cardiovascular Events",
"has_exemption": false,
"start_date": "2024-03-06",
"completion_date": "2029-03-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Cleerly, Inc.",
"sponsor_slug": "cleerly-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06534983",
"publication_url": "https://clinicaltrials.gov/study/NCT06534983",
"title": "A Randomized Phase II, Double-blind, Multicenter Study Evaluating the Efficacy and Safety of Autogene Cevumeran Plus Nivolumab Versus Nivolumab as Adjuvant Therapy in Patients With High-risk Muscle-invasive Urothelial Carcinoma",
"has_exemption": false,
"start_date": "2024-12-09",
"completion_date": "2029-03-07",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227298",
"publication_url": "https://clinicaltrials.gov/study/NCT07227298",
"title": "AN INTERVENTIONAL OPEN-LABEL PHASE 1B/2 STUDY TO EVALUATE THE SAFETY, PHARMACOKINETICS, AND PRELIMINARY EFFICACY OF PF-08634404 IN COMBINATION WITH DIFFERENT ANTICANCER AGENTS IN PARTICIPANTS WITH ADVANCED SOLID TUMORS",
"has_exemption": false,
"start_date": "2025-11-17",
"completion_date": "2029-03-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05142696",
"publication_url": "https://clinicaltrials.gov/study/NCT05142696",
"title": "A Phase Ib/II Dose Finding Study Assessing Safety and Efficacy of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Extensive Stage Small Cell Lung Cancer (ES-SCLC) in Combination With Carboplatin, Etoposide, and Atezolizumab in Induction and With Atezolizumab in Maintenance Phase",
"has_exemption": false,
"start_date": "2022-07-13",
"completion_date": "2029-03-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05174169",
"publication_url": "https://clinicaltrials.gov/study/NCT05174169",
"title": "Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease",
"has_exemption": false,
"start_date": "2022-03-10",
"completion_date": "2029-03-10",
"has_results": false,
"results_due": false,
"sponsor_name": "NRG Oncology",
"sponsor_slug": "nrg-oncology",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06274528",
"publication_url": "https://clinicaltrials.gov/study/NCT06274528",
"title": "Effect of a Dual Orexin Receptor Antagonist on CSF Alzheimer's Disease Biomarkers",
"has_exemption": false,
"start_date": "2024-03-11",
"completion_date": "2029-03-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06883305",
"publication_url": "https://clinicaltrials.gov/study/NCT06883305",
"title": "A Randomised, Double-blind, Placebo-controlled, Parallel Group, Multicentre, Phase III Study to Evaluate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease",
"has_exemption": false,
"start_date": "2025-03-18",
"completion_date": "2029-03-13",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06878261",
"publication_url": "https://clinicaltrials.gov/study/NCT06878261",
"title": "A Randomised, Double-blind, Placebo-controlled, Parallel Group, Multicentre, Phase III Study to Evaluate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease",
"has_exemption": false,
"start_date": "2025-03-25",
"completion_date": "2029-03-13",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05827016",
"publication_url": "https://clinicaltrials.gov/study/NCT05827016",
"title": "A Phase 3, Two-stage, Randomized, Multi-center, Controlled, Open-label Study Comparing Iberdomide Maintenance to Lenalidomide Maintenance Therapy After Autologous Stem Cell Transplantation (ASCT) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) (EXCALIBER-Maintenance)",
"has_exemption": false,
"start_date": "2023-06-22",
"completion_date": "2029-03-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04305691",
"publication_url": "https://clinicaltrials.gov/study/NCT04305691",
"title": "A Phase 2 Trial of Ixazomib for Kaposi Sarcoma",
"has_exemption": false,
"start_date": "2023-11-07",
"completion_date": "2029-03-15",
"has_results": false,
"results_due": false,
"sponsor_name": "AIDS Malignancy Consortium",
"sponsor_slug": "aids-malignancy-consortium",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07225361",
"publication_url": "https://clinicaltrials.gov/study/NCT07225361",
"title": "Ublituximab (Briumvi) for Early Forms of Relapsing Multiple Sclerosis",
"has_exemption": false,
"start_date": "2025-11-28",
"completion_date": "2029-03-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06921785",
"publication_url": "https://clinicaltrials.gov/study/NCT06921785",
"title": "A Phase III, Randomised, Open-label, Sponsor-blinded, Multicentre Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma",
"has_exemption": false,
"start_date": "2025-05-06",
"completion_date": "2029-03-16",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07238400",
"publication_url": "https://clinicaltrials.gov/study/NCT07238400",
"title": "Cardiac Effects of Mineralocorticoid Receptor Antagonism After Preeclampsia",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2029-03-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05855200",
"publication_url": "https://clinicaltrials.gov/study/NCT05855200",
"title": "A Phase 3, Open-Label, Randomized Study of Perioperative Dostarlimab Monotherapy Versus Standard of Care in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer",
"has_exemption": false,
"start_date": "2023-08-01",
"completion_date": "2029-03-19",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07332481",
"publication_url": "https://clinicaltrials.gov/study/NCT07332481",
"title": "A Phase 3, Randomized, Double-Blind,Placebo-Controlled Parallel Study to Evaluate the Efficacy and Safety of Enpatoran in Participants With Active Cutaneous Manifestations of Lupus Erythematosus With or Without Systemic Disease Receiving Standard of Care (Elowen-1)",
"has_exemption": false,
"start_date": "2026-02-25",
"completion_date": "2029-03-19",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany",
"sponsor_slug": "merck-healthcare-kgaa-darmstadt-germany-an-affiliate-of-merck-kgaa-darmstadt-germany",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06787950",
"publication_url": "https://clinicaltrials.gov/study/NCT06787950",
"title": "A Phase I/IIa Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Anti-tumor Activity of ASN-3186 in Patients with Advanced Solid Tumors.",
"has_exemption": false,
"start_date": "2025-02-20",
"completion_date": "2029-03-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Jiangsu Yahong Meditech Co., Ltd aka Asieris",
"sponsor_slug": "jiangsu-yahong-meditech-co-ltd-aka-asieris",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07316010",
"publication_url": "https://clinicaltrials.gov/study/NCT07316010",
"title": "Phase 2 Trial of Lisocabtagene Maraleucel for Minimal Residual Disease in Patients With Large B-cell Lymphoma",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2029-03-21",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06439082",
"publication_url": "https://clinicaltrials.gov/study/NCT06439082",
"title": "A Phase III, Multicenter, Randomized, Placebo Controlled, Double-blind Study to Assess Efficacy and Safety of Crizanlizumab (5 mg/kg) Versus Placebo, With or Without Hydroxyurea/Hydroxycarbamide Therapy, in Adolescent and Adult Sickle Cell Disease Patients With Frequent Vaso-Occlusive Crises",
"has_exemption": false,
"start_date": "2024-10-24",
"completion_date": "2029-03-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06669572",
"publication_url": "https://clinicaltrials.gov/study/NCT06669572",
"title": "A Phase II, Multi-center, Single Arm Trial of Lenvatinib Plus Pembrolizumab in Patients With Unresectable Locally Advanced and/or Metastatic Anorectal Squamous Cell Carcinoma (ASCC) After Progression on First Line Chemotherapy.",
"has_exemption": false,
"start_date": "2026-01-13",
"completion_date": "2029-03-26",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06843447",
"publication_url": "https://clinicaltrials.gov/study/NCT06843447",
"title": "A Phase 1b/2 Open-label, Multicenter Study to Evaluate the Safety and Efficacy of Raludotatug Deruxtecan With or Without Other Anticancer Investigational Agents in Participants With High-grade Serous Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Who Have Relapsed After Prior Platinum-based Chemotherapy",
"has_exemption": false,
"start_date": "2025-04-15",
"completion_date": "2029-03-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07060365",
"publication_url": "https://clinicaltrials.gov/study/NCT07060365",
"title": "A Master Protocol Phase I/II Study to Investigate Biomarker-Guided Novel Anticancer Agent(s) as Monotherapy or Combination Therapy for the Treatment of Participants With Advanced/Recurrent Ovarian Cancer (Ovarian Platform)",
"has_exemption": false,
"start_date": "2025-09-02",
"completion_date": "2029-03-27",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06347705",
"publication_url": "https://clinicaltrials.gov/study/NCT06347705",
"title": "Phase II Study Evaluating the Effects of Single Site Intratumoral Injections of Anti-CD40 Agonist Antibody (2141-V11) Given as Monotherapy Prior to Radical Prostatectomy to Men With Intermediate Risk Disease and in Combination With Androgen Deprivation Therapy for Those With High Risk Localized and Low Volume Metastatic Disease",
"has_exemption": false,
"start_date": "2024-03-28",
"completion_date": "2029-03-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07037862",
"publication_url": "https://clinicaltrials.gov/study/NCT07037862",
"title": "A 2-Part, Randomized, Double-Blind, Placebo-Controlled Study in Participants With Duchenne Muscular Dystrophy Amenable to Exon 44 Skipping With an Initial Multiple Ascending Dose Part A to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ENTR-601-44, Followed by Part B to Evaluate the Safety and Efficacy of ENTR-601-44 (ELEVATE-44)",
"has_exemption": false,
"start_date": "2025-06-30",
"completion_date": "2029-03-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Entrada Therapeutics, Inc.",
"sponsor_slug": "entrada-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06997497",
"publication_url": "https://clinicaltrials.gov/study/NCT06997497",
"title": "A Phase 3, Randomized, Open-label, Multicenter Clinical Study to Evaluate the Safety and Efficacy of MK-1084, Cetuximab, and mFOLFOX6 Versus mFOLFOX6 With or Without Bevacizumab as First-line Treatment of Participants With KRAS G12C-mutant, Locally Advanced Unresectable or Metastatic Colorectal Cancer (KANDLELIT-012)",
"has_exemption": false,
"start_date": "2025-07-16",
"completion_date": "2029-03-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07192614",
"publication_url": "https://clinicaltrials.gov/study/NCT07192614",
"title": "A Phase I/II Open-label, Dose Escalation and Dose Expansion Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of AZD6621, a T Cell-engaging Antibody That Targets STEAP2, CD3, and CD8 in Adult Participants With Metastatic Prostate Cancer",
"has_exemption": false,
"start_date": "2025-09-30",
"completion_date": "2029-03-29",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07046910",
"publication_url": "https://clinicaltrials.gov/study/NCT07046910",
"title": "Advanced Immunoclinical Phenotyping of Rejection in Lung Transplant",
"has_exemption": false,
"start_date": "2019-04-01",
"completion_date": "2029-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Virginia",
"sponsor_slug": "university-of-virginia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05039515",
"publication_url": "https://clinicaltrials.gov/study/NCT05039515",
"title": "A Phase 2 Study to Assess the Efficacy and Safety of 2 Dosage Regimens of Oral Fidrisertib (IPN60130) for the Treatment of Fibrodysplasia Ossificans Progressiva in Male and Female Paediatric and Adult Participants.",
"has_exemption": false,
"start_date": "2021-12-01",
"completion_date": "2029-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Clementia Pharmaceuticals Inc.",
"sponsor_slug": "clementia-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05651594",
"publication_url": "https://clinicaltrials.gov/study/NCT05651594",
"title": "A Phase 2 Trial of Chemotherapy, Pembrolizumab, and Propranolol in Advanced Esophageal/Gastroesophageal Junction Adenocarcinoma Patients",
"has_exemption": false,
"start_date": "2023-03-07",
"completion_date": "2029-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Roswell Park Cancer Institute",
"sponsor_slug": "roswell-park-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06380751",
"publication_url": "https://clinicaltrials.gov/study/NCT06380751",
"title": "A Randomised, Open-Label, Phase III Study of Saruparib (AZD5305) Plus Camizestrant Compared With Physician's Choice CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant for the First-Line Treatment of Patients With BRCA1, BRCA2, or PALB2 Mutations and Hormone Receptor Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified) Advanced Breast Cancer (EvoPAR-Breast01)",
"has_exemption": false,
"start_date": "2024-08-01",
"completion_date": "2029-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06778434",
"publication_url": "https://clinicaltrials.gov/study/NCT06778434",
"title": "Acid Sphingomyelinase Inhibition to Mitigate the Environmental Exposure Risks of Ultraviolet Light-Induced Actinic Neoplasia and Squamous Cell Carcinoma in US Veterans",
"has_exemption": false,
"start_date": "2025-04-01",
"completion_date": "2029-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06814145",
"publication_url": "https://clinicaltrials.gov/study/NCT06814145",
"title": "A Phase 2, Multicenter, Double-blind, Extension Study to Evaluate the Effects of Sotatercept for the Treatment of Combined Postcapillary and Precapillary Pulmonary Hypertension (Cpc-PH) Due to Heart Failure With Preserved Ejection Fraction (HFpEF)",
"has_exemption": false,
"start_date": "2025-04-16",
"completion_date": "2029-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06918431",
"publication_url": "https://clinicaltrials.gov/study/NCT06918431",
"title": "A Phase 2 Study Evaluating the Safety and Efficacy of Asparaginase Erwinia Chrysanthemi- Recombinant-Rywn (Recombinant Erwinia Asparaginase) During Pediatric-Inspired Regimen in High-Risk Adults With Newly Diagnosed ALL or LBL",
"has_exemption": false,
"start_date": "2025-10-10",
"completion_date": "2029-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "City of Hope Medical Center",
"sponsor_slug": "city-of-hope-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT00185744",
"publication_url": "https://clinicaltrials.gov/study/NCT00185744",
"title": "Accelerated Partial Breast Irradiation Following Lumpectomy for Breast Cancer",
"has_exemption": false,
"start_date": "2002-09-30",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03153475",
"publication_url": "https://clinicaltrials.gov/study/NCT03153475",
"title": "Multi-Center Clinical Evaluation of the ATTUNE® Revision System in Revision Total Knee Arthroplasty",
"has_exemption": false,
"start_date": "2017-05-30",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "DePuy Orthopaedics",
"sponsor_slug": "depuy-orthopaedics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03167203",
"publication_url": "https://clinicaltrials.gov/study/NCT03167203",
"title": "A Safety Surveillance Study of Events of Special Interest Occurring in Subjects With Macular Degenerative Disease Treated With Human Embryonic Stem Cell-derived Retinal Pigment Epithelial Cell Therapy",
"has_exemption": false,
"start_date": "2018-01-08",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Astellas Institute for Regenerative Medicine",
"sponsor_slug": "astellas-institute-for-regenerative-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03493425",
"publication_url": "https://clinicaltrials.gov/study/NCT03493425",
"title": "Phase II Randomized Trial of Neo-Adjuvant Chemotherapy Followed by Surgery and Post-Operative Radiation Versus Surgery and Post-Operative Radiation for Organ Preservation of T3 and T4a Nasal and Paranasal Sinus Squamous Cell Carcinoma (NPNSCC)",
"has_exemption": false,
"start_date": "2019-03-12",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ECOG-ACRIN Cancer Research Group",
"sponsor_slug": "ecog-acrin-cancer-research-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04333576",
"publication_url": "https://clinicaltrials.gov/study/NCT04333576",
"title": "A Phase 3b Study to Evaluate the Safety and Efficacy of Elagolix in Combination With Combined Oral Contraceptives in Premenopausal Women With Documented Endometriosis and Associated Moderate to Severe Pain",
"has_exemption": false,
"start_date": "2020-08-10",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04740476",
"publication_url": "https://clinicaltrials.gov/study/NCT04740476",
"title": "An Open-Label Extension Study for Patients With Dravet Syndrome Who Previously Participated in Studies of STK-001",
"has_exemption": false,
"start_date": "2021-01-20",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stoke Therapeutics, Inc",
"sponsor_slug": "stoke-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04884815",
"publication_url": "https://clinicaltrials.gov/study/NCT04884815",
"title": "An Operationally Seamless Phase 1/2/3 Study Consisting of a Safety and Dose-finding Phase 1/2 and Randomized, Open-label, Active-controlled Phase 3 to Evaluate UX701 AAV Gene Therapy in Adults With Wilson Disease",
"has_exemption": false,
"start_date": "2021-09-27",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ultragenyx Pharmaceutical Inc",
"sponsor_slug": "ultragenyx-pharmaceutical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05127226",
"publication_url": "https://clinicaltrials.gov/study/NCT05127226",
"title": "HALOS: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intrathecally Administered ION582 in Patients With Angelman Syndrome",
"has_exemption": false,
"start_date": "2021-12-22",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ionis Pharmaceuticals, Inc.",
"sponsor_slug": "ionis-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05595473",
"publication_url": "https://clinicaltrials.gov/study/NCT05595473",
"title": "A Phase 1/2a, Open-label, Multicenter, Dose Escalation and Dose Expansion Study Evaluating the Safety, Tolerability and Efficacy of RZ-001 in Combination with Valganciclovir in Subjects with Hepatocellular Carcinoma",
"has_exemption": false,
"start_date": "2022-07-29",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Rznomics, Inc.",
"sponsor_slug": "rznomics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05619146",
"publication_url": "https://clinicaltrials.gov/study/NCT05619146",
"title": "Upper and Lower Extremity Cycling in Incomplete Spinal Cord Injury Individuals to Promote Limb Recovery",
"has_exemption": false,
"start_date": "2023-01-23",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Shirley Ryan AbilityLab",
"sponsor_slug": "shirley-ryan-abilitylab",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05721755",
"publication_url": "https://clinicaltrials.gov/study/NCT05721755",
"title": "Phase III Randomized Trial of Immunotherapy With or Without Consolidative Radiotherapy for Oligometastatic Head and Neck Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2023-06-08",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ECOG-ACRIN Cancer Research Group",
"sponsor_slug": "ecog-acrin-cancer-research-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06305286",
"publication_url": "https://clinicaltrials.gov/study/NCT06305286",
"title": "A Pilot Study Assessing the Safety of Using a Monoclonal Antibody Against Cluster of Differentiation 40 (CD40) Ligand to Achieve a Calcineurin Inhibitor-free Immunosuppression Regimen in Patients With Type 1 Diabetes Mellitus (T1D) and Problematic Hypoglycemia Undergoing Islet Cell Transplantation",
"has_exemption": false,
"start_date": "2024-03-04",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06292013",
"publication_url": "https://clinicaltrials.gov/study/NCT06292013",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) Who Have Established Atherosclerotic Cardiovascular Disease or Are at Risk for a First Cardiovascular Event - ACCLAIM-Lp(a)",
"has_exemption": false,
"start_date": "2024-03-05",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06350318",
"publication_url": "https://clinicaltrials.gov/study/NCT06350318",
"title": "A Phase 2 Open-Label, Multicenter Study of Rituximab and Zanubrutinib in Patients With Indolent B-cell Lymphomas",
"has_exemption": false,
"start_date": "2024-04-19",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05977400",
"publication_url": "https://clinicaltrials.gov/study/NCT05977400",
"title": "NICU Antibiotics and Outcomes Follow-Up Study",
"has_exemption": false,
"start_date": "2024-04-30",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sharp HealthCare",
"sponsor_slug": "sharp-healthcare",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06395103",
"publication_url": "https://clinicaltrials.gov/study/NCT06395103",
"title": "LIGHTBEAM-U01 Substudy 01A: A Phase 1/2 Substudy to Evaluate the Safety and Efficacy of Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors",
"has_exemption": false,
"start_date": "2024-08-16",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06102525",
"publication_url": "https://clinicaltrials.gov/study/NCT06102525",
"title": "A Phase 1/2a, Open-label, Multicenter, Dose Escalation and Dose Expansion Study Evaluating the Safety, Tolerability, and Efficacy of RZ-001 in Combination With Valganciclovir in Subjects With Glioblastoma",
"has_exemption": false,
"start_date": "2024-10-08",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Rznomics, Inc.",
"sponsor_slug": "rznomics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06798558",
"publication_url": "https://clinicaltrials.gov/study/NCT06798558",
"title": "Phase II Study of Neoadjuvant Lu-177-PSMA-617 in Patients With High Risk Localized Prostate Cancer Undergoing Radical Prostatectomy",
"has_exemption": false,
"start_date": "2025-03-05",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hackensack Meridian Health",
"sponsor_slug": "hackensack-meridian-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06542705",
"publication_url": "https://clinicaltrials.gov/study/NCT06542705",
"title": "Effect of Internal Brace on Outcomes Following ACL Reconstruction With Bone Patellar Bone (BTB) Autograft: A Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2025-03-17",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06647953",
"publication_url": "https://clinicaltrials.gov/study/NCT06647953",
"title": "Prospective Treatment of Types I, II and III Pleuropulmonary Blastoma (PPB)",
"has_exemption": false,
"start_date": "2025-03-21",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06880770",
"publication_url": "https://clinicaltrials.gov/study/NCT06880770",
"title": "Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Plozasiran in Adults With Severe Hypertriglyceridemia at High Risk of Acute Pancreatitis (SHASTA-5 Study)",
"has_exemption": false,
"start_date": "2025-04-24",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Arrowhead Pharmaceuticals",
"sponsor_slug": "arrowhead-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06682793",
"publication_url": "https://clinicaltrials.gov/study/NCT06682793",
"title": "A Seamless Phase 1/2 Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated Tmod™ CAR T, in Heterozygous HLA-A*02 Adults With Recurrent Unresectable, Locally Advanced, or Metastatic Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression",
"has_exemption": false,
"start_date": "2025-05-22",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "A2 Biotherapeutics Inc.",
"sponsor_slug": "a2-biotherapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06839235",
"publication_url": "https://clinicaltrials.gov/study/NCT06839235",
"title": "A Phase 1/2 Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of ABO-101 in Participants With Primary Hyperoxaluria Type 1 (PH1)",
"has_exemption": false,
"start_date": "2025-06-16",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Arbor Biotechnologies",
"sponsor_slug": "arbor-biotechnologies",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07098988",
"publication_url": "https://clinicaltrials.gov/study/NCT07098988",
"title": "A Ph2, Randomized, Blinded, Placebo-Controlled Trial Investigating the Efficacy and Safety of Visugromab Versus Placebo, in Combination With Pembrolizumab, Pemetrexed, and Carboplatin, in 1L Treatment of Participants With Metastatic NSCLC (GDFATHER-NSCLC-01)",
"has_exemption": false,
"start_date": "2025-08-01",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "CatalYm GmbH",
"sponsor_slug": "catalym-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07145736",
"publication_url": "https://clinicaltrials.gov/study/NCT07145736",
"title": "Moxidectin Versus Ivermectin as Mass Drug Administration for the Control of Onchocerciasis and Other Neglected Tropical Diseases: A Cluster-randomised Trial",
"has_exemption": false,
"start_date": "2025-08-04",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kirby Institute",
"sponsor_slug": "kirby-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07016698",
"publication_url": "https://clinicaltrials.gov/study/NCT07016698",
"title": "A Prospective, Multicenter, Single Arm, Real-World Registry Assessing the Clinical Use of the Rotarex(TM) Rotational Excisional Atherectomy System (XTRACT Registry)",
"has_exemption": false,
"start_date": "2025-09-29",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "C. R. Bard",
"sponsor_slug": "c-r-bard",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07132918",
"publication_url": "https://clinicaltrials.gov/study/NCT07132918",
"title": "The cARdiac Radiation Therapy Sparing (HEARTS) for Thoracic Cancers",
"has_exemption": false,
"start_date": "2025-10-08",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07218783",
"publication_url": "https://clinicaltrials.gov/study/NCT07218783",
"title": "A Prospective, Multicenter, Randomized, Masked, Controlled Study to Evaluate the Safety and Efficacy of the Bimatoprost Implant System (78 mcg) Used in Combination With the SpyGlass IOL Compared to Timolol Maleate Ophthalmic Solution, USP, 0.5%,",
"has_exemption": false,
"start_date": "2025-10-15",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "SpyGlass Pharma, Inc.",
"sponsor_slug": "spyglass-pharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06844383",
"publication_url": "https://clinicaltrials.gov/study/NCT06844383",
"title": "A Randomized Open-label Phase 2 Study of TALazoparib With or Without ENzaluTamide in Patients With Metastatic Castration-Resistant Prostate Cancer and HRR Mutations After Progression on Abiraterone Acetate",
"has_exemption": false,
"start_date": "2025-10-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Prostate Cancer Clinical Trials Consortium",
"sponsor_slug": "prostate-cancer-clinical-trials-consortium",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06155682",
"publication_url": "https://clinicaltrials.gov/study/NCT06155682",
"title": "Cognitive and Neural Correlates of TMS Motor Intracortical Inhibition in Schizophrenia",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Maryland, Baltimore",
"sponsor_slug": "university-of-maryland-baltimore",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07209332",
"publication_url": "https://clinicaltrials.gov/study/NCT07209332",
"title": "An Open-Label Extension Study to Investigate the Long-term Safety, Tolerability, Pharmacokinetics, and Efficacy of WVE-N531 in Patients With Duchenne Muscular Dystrophy Who Participated in Another Study of WVE-N531",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Wave Life Sciences Ltd.",
"sponsor_slug": "wave-life-sciences-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06224673",
"publication_url": "https://clinicaltrials.gov/study/NCT06224673",
"title": "Phase II Open-label Study of ARX788 (Anti-HER2 Antibody Drug Conjugate (ADC)) for Patients With HER2-low Locally Advanced Unresectable or Metastatic Breast Cancer",
"has_exemption": false,
"start_date": "2025-12-18",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Laura Huppert, MD, BA",
"sponsor_slug": "laura-huppert-md-ba",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07227207",
"publication_url": "https://clinicaltrials.gov/study/NCT07227207",
"title": "A Phase 1/2, Open-Label, Multi-Center, Dose Escalation, Dose Expansion, and Single Repeat Dose Study of TSRA-196 in Adults With the PiZZ Genotype Who Have Lung and/or Liver Disease Associated With Severe Alpha-1 Antitrypsin Deficiency",
"has_exemption": false,
"start_date": "2025-12-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Tessera Therapeutics, Inc.",
"sponsor_slug": "tessera-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07262619",
"publication_url": "https://clinicaltrials.gov/study/NCT07262619",
"title": "A Multicenter, Multi-Part, Phase 1/2 Study of EIK1005 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors, Including Checkpoint Inhibitor Naïve Participants With Microsatellite Instability High (MSI-H) or Mismatch Repair Deficient (dMMR) Tumors",
"has_exemption": false,
"start_date": "2025-12-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eikon Therapeutics",
"sponsor_slug": "eikon-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07109817",
"publication_url": "https://clinicaltrials.gov/study/NCT07109817",
"title": "Desloratadine to Prevent Taxane-induced Peripheral Neuropathy in Patients With Breast Cancer (DETOXp)",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Montefiore Medical Center",
"sponsor_slug": "montefiore-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07135050",
"publication_url": "https://clinicaltrials.gov/study/NCT07135050",
"title": "Phase 1/2 First-in-Human Study to Evaluate the Safety, Tolerability, and Efficacy of MZ-1866, an AAV-9 Gene Therapy Delivered by Intracerebroventricular Injection to Participants With Pitt Hopkins Syndrome",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mahzi Therapeutics",
"sponsor_slug": "mahzi-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06240455",
"publication_url": "https://clinicaltrials.gov/study/NCT06240455",
"title": "A Double-blind, Placebo-controlled, Phase 2 Dose-range Study to Assess the Efficacy and Safety of WP1302 in Preventing Disease Relapse Following Methimazole Withdrawal in Subjects With Graves' Disease",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Worg Biotherapeutics Inc.",
"sponsor_slug": "worg-biotherapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07224763",
"publication_url": "https://clinicaltrials.gov/study/NCT07224763",
"title": "EXTEND: A Prospective Study to Evaluate the Safety and Efficacy of GGTA1 KO Thymokidney XenoTransplantation in Patients With End-stage Renal Disease (ESRD)",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "United Therapeutics",
"sponsor_slug": "united-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07288437",
"publication_url": "https://clinicaltrials.gov/study/NCT07288437",
"title": "Adaptive Deep Brain Stimulation Targeting the Dentate Nucleus to Treat Spinocerebellar Ataxia",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07060417",
"publication_url": "https://clinicaltrials.gov/study/NCT07060417",
"title": "The Effects of SGLT2 Inhibition on Vascular Health and Physical Function in Veterans With CKD",
"has_exemption": false,
"start_date": "2026-04-01",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07104318",
"publication_url": "https://clinicaltrials.gov/study/NCT07104318",
"title": "Randomized Clinical Trial of Personalized vs Standard of Care Treatment for Helicobacter Pylori Eradication Among Veterans: \"VA Eradicate HP\"",
"has_exemption": false,
"start_date": "2026-04-01",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07078838",
"publication_url": "https://clinicaltrials.gov/study/NCT07078838",
"title": "A Randomized, Window of Opportunity Trial of Tirzepatide in Women With Obesity and a Diagnosis of Endometrial Intra-epithelial Neoplasia (EIN) or Grade 1 Endometrial Cancer",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "UNC Lineberger Comprehensive Cancer Center",
"sponsor_slug": "unc-lineberger-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07293546",
"publication_url": "https://clinicaltrials.gov/study/NCT07293546",
"title": "An Open-Label First-in-Human Phase 1/2 Study to Evaluate the Safety, Tolerability, and Efficacy of FRF-001, an AAV-9 Gene Therapy Administered by Intracerebroventricular Injection in Participants With FOXG1 Syndrome",
"has_exemption": false,
"start_date": "2026-04-30",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "FOXG1 Research Foundation",
"sponsor_slug": "foxg1-research-foundation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06855043",
"publication_url": "https://clinicaltrials.gov/study/NCT06855043",
"title": "Pilot Randomized Controlled Trial of Late Surfactant Therapy With Budesonide for Prevention of Bronchopulmonary Dysplasia",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06167213",
"publication_url": "https://clinicaltrials.gov/study/NCT06167213",
"title": "Safety and Effectiveness of Balloon-Expandable Bioprosthetic SAPIEN X4 Transcatheter Heart Valve - Mitral",
"has_exemption": false,
"start_date": "2027-01-31",
"completion_date": "2029-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Edwards Lifesciences",
"sponsor_slug": "edwards-lifesciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04364178",
"publication_url": "https://clinicaltrials.gov/study/NCT04364178",
"title": "Viral Specific T-Lymphocytes by Cytokine Capture System (CCS) to Treat Infection With Adenovirus or Cytomegalovirus After Hematopoietic Cell Transplantation or Solid Organ Transplantation and in Patients With Compromised Immunity",
"has_exemption": false,
"start_date": "2020-08-12",
"completion_date": "2029-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Jessie L. Alexander",
"sponsor_slug": "jessie-l-alexander",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04682158",
"publication_url": "https://clinicaltrials.gov/study/NCT04682158",
"title": "Propranolol With Standard Chemoradiation for Esophageal Adenocarcinoma A Phase II Study",
"has_exemption": false,
"start_date": "2021-04-01",
"completion_date": "2029-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Roswell Park Cancer Institute",
"sponsor_slug": "roswell-park-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06499805",
"publication_url": "https://clinicaltrials.gov/study/NCT06499805",
"title": "Barriers and Facilitators to OTC Hearing Aids Success",
"has_exemption": false,
"start_date": "2025-03-15",
"completion_date": "2029-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Yu-Hsiang Wu",
"sponsor_slug": "yu-hsiang-wu",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06828991",
"publication_url": "https://clinicaltrials.gov/study/NCT06828991",
"title": "ctDNA-Guided Mosunetuzumab Consolidation Therapy in Older Patients With Untreated DLBCL",
"has_exemption": false,
"start_date": "2025-09-04",
"completion_date": "2029-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Danielle Wallace",
"sponsor_slug": "danielle-wallace",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06574009",
"publication_url": "https://clinicaltrials.gov/study/NCT06574009",
"title": "Better Options for Chronic Cancer Pain: a SMART Study",
"has_exemption": false,
"start_date": "2025-10-07",
"completion_date": "2029-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06834217",
"publication_url": "https://clinicaltrials.gov/study/NCT06834217",
"title": "Characterization and Modulation of Functional Connectivity and Fear Extinction Abnormalities in Obsessive-Compulsive Disorder",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2029-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06863402",
"publication_url": "https://clinicaltrials.gov/study/NCT06863402",
"title": "Nemtabrutinib and Pembrolizumab in Patients With Richter Transformation: A Phase II Study",
"has_exemption": false,
"start_date": "2026-02-15",
"completion_date": "2029-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Roswell Park Cancer Institute",
"sponsor_slug": "roswell-park-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07169734",
"publication_url": "https://clinicaltrials.gov/study/NCT07169734",
"title": "A Phase I/II, Open-label, Multicenter Study of ALE.P03 (Claudin-1 Targeted Antibody-drug Conjugate) as a Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors",
"has_exemption": false,
"start_date": "2025-08-26",
"completion_date": "2029-04-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Alentis Therapeutics AG",
"sponsor_slug": "alentis-therapeutics-ag",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06068881",
"publication_url": "https://clinicaltrials.gov/study/NCT06068881",
"title": "A Phase 2, Open-label, Single-Arm Clinical Trial to Investigate the Efficacy and Safety of Oral Tazemetostat for the Treatment of Adult Participants Age 18 and Over With Relapsed/Refractory Follicular Lymphoma Lacking the EZH2 Gain-of-Function (GOF) Mutation",
"has_exemption": false,
"start_date": "2025-09-02",
"completion_date": "2029-04-06",
"has_results": false,
"results_due": false,
"sponsor_name": "Epizyme, Inc.",
"sponsor_slug": "epizyme-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06894511",
"publication_url": "https://clinicaltrials.gov/study/NCT06894511",
"title": "A Phase II, Open-label, Multi-Center, Randomized Study Comparing the Combination of Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) and Androgen Receptor Pathway Inhibitor (ARPI) vs. Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in First-line Treatment of Patients With Prostate-Specific Membrane Antigen (PSMA)-Positive Progressive Metastatic Castration Resistant Prostate Cancer (mCRPC)",
"has_exemption": false,
"start_date": "2025-09-11",
"completion_date": "2029-04-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07354100",
"publication_url": "https://clinicaltrials.gov/study/NCT07354100",
"title": "Bifidobacterium Lactulose Optimization in Oncology and Microbiome (BLOOM)",
"has_exemption": false,
"start_date": "2026-01-15",
"completion_date": "2029-04-13",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06410001",
"publication_url": "https://clinicaltrials.gov/study/NCT06410001",
"title": "CE-STAND: Cervical Epidural STimulation After Neurologic Damage",
"has_exemption": false,
"start_date": "2026-03-01",
"completion_date": "2029-04-15",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Minnesota",
"sponsor_slug": "university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05739383",
"publication_url": "https://clinicaltrials.gov/study/NCT05739383",
"title": "A Randomized, Double-blind, Placebo-controlled Multicenter Study to Evaluate the Effect of Inclisiran on Preventing Major Adverse Cardiovascular Events in High-risk Primary Prevention Patients (VICTORION-1 PREVENT)",
"has_exemption": false,
"start_date": "2023-03-09",
"completion_date": "2029-04-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06740526",
"publication_url": "https://clinicaltrials.gov/study/NCT06740526",
"title": "A Phase 2b, Multicenter, Open-label, Single-arm Trial to Evaluate the Impact of Sibeprenlimab on Kidney Histopathology Through Repeat Kidney Biopsies in Adolescents and Adults With Immunoglobulin A Nephropathy",
"has_exemption": false,
"start_date": "2024-11-19",
"completion_date": "2029-04-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Otsuka Pharmaceutical Development & Commercialization, Inc.",
"sponsor_slug": "otsuka-pharmaceutical-development-commercialization-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07092514",
"publication_url": "https://clinicaltrials.gov/study/NCT07092514",
"title": "Randomized Phase II Trial of Lenvatinib 24 mg/Day Versus 10 mg/Day to Treat Symptomatic or Progressive Radioactive Iodine Resistant (RAIR) Differentiated Thyroid Cancer (DTC)",
"has_exemption": false,
"start_date": "2025-10-14",
"completion_date": "2029-04-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07325136",
"publication_url": "https://clinicaltrials.gov/study/NCT07325136",
"title": "A Phase 1/2 Study of BMS-986525 as Monotherapy and in Combination With Nivolumab in Participants With Relapsed/Refractory Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2026-02-18",
"completion_date": "2029-04-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04822181",
"publication_url": "https://clinicaltrials.gov/study/NCT04822181",
"title": "The Effect of Semaglutide in Subjects With Non-cirrhotic Non-alcoholic Steatohepatitis",
"has_exemption": false,
"start_date": "2021-04-01",
"completion_date": "2029-04-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Novo Nordisk A/S",
"sponsor_slug": "novo-nordisk-as",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05406401",
"publication_url": "https://clinicaltrials.gov/study/NCT05406401",
"title": "A Multicenter, Open-label, Phase 2 Dose Escalation and Confirmation, and Efficacy Expansion Study of Zilovertamab Vedotin (MK-2140) in Combination With R-CHP in Participants With DLBCL (waveLINE)",
"has_exemption": false,
"start_date": "2022-07-14",
"completion_date": "2029-04-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06764875",
"publication_url": "https://clinicaltrials.gov/study/NCT06764875",
"title": "A Randomized, Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan Versus Trastuzumab, Chemotherapy, and Pembrolizumab for the First Line Treatment of HER2-positive Gastric Cancer (ARTEMIDE-Gastric01)",
"has_exemption": false,
"start_date": "2025-03-01",
"completion_date": "2029-04-27",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06824467",
"publication_url": "https://clinicaltrials.gov/study/NCT06824467",
"title": "A Phase 3, Randomized, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan Maintenance Treatment With or Without Bevacizumab Versus Standard of Care After Second-line Platinum-based Doublet Chemotherapy in Participants With Platinum-sensitive Recurrent Ovarian Cancer (TroFuse-022/ENGOT-ov84/GOG-3103)",
"has_exemption": false,
"start_date": "2025-04-09",
"completion_date": "2029-04-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07284433",
"publication_url": "https://clinicaltrials.gov/study/NCT07284433",
"title": "A Single-arm, Multicenter, Open-label, Phase I/II Trial of Allo-QuadCAR01-T, an Allogeneic CAR-T-cell Therapy Targeting CD19 and CD20, for the Treatment of Relapsed or Refractory B-cell Malignancies",
"has_exemption": false,
"start_date": "2026-01-06",
"completion_date": "2029-04-27",
"has_results": false,
"results_due": false,
"sponsor_name": "AvenCell Therapeutics, Inc.",
"sponsor_slug": "avencell-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07366034",
"publication_url": "https://clinicaltrials.gov/study/NCT07366034",
"title": "A Study to Evaluate the Dose-exposure, Safety, and Exploratory Efficacy of Nerandomilast in Children and Adolescents From 2 Years to Less Than 18 Years of Age With Fibrosing Interstitial Lung Disease (Part A: Double-blind, Placebo-controlled in Children From 6 to Less Than 18 Years of Age and Open-label Active Treatment in Children From 2 to Less Than 6 Years of Age), Followed by an Open-label Phase With Active Treatment (Part B)",
"has_exemption": false,
"start_date": "2026-06-15",
"completion_date": "2029-04-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Boehringer Ingelheim",
"sponsor_slug": "boehringer-ingelheim",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04156893",
"publication_url": "https://clinicaltrials.gov/study/NCT04156893",
"title": "RH Genotype Matched Red Cell Transfusions for Patients With Sickle Cell Disease",
"has_exemption": false,
"start_date": "2020-01-30",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Hospital of Philadelphia",
"sponsor_slug": "childrens-hospital-of-philadelphia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04684940",
"publication_url": "https://clinicaltrials.gov/study/NCT04684940",
"title": "A Phase 1/2 Safety, Tolerability, and Efficacy Study of BMN 270, an Adeno-Associated Virus Vector-Mediated Gene Transfer of Human Factor VIII in Hemophilia A Patients With Active or Prior Inhibitors",
"has_exemption": false,
"start_date": "2020-12-10",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "BioMarin Pharmaceutical",
"sponsor_slug": "biomarin-pharmaceutical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04534205",
"publication_url": "https://clinicaltrials.gov/study/NCT04534205",
"title": "An Open-label Phase II/III Randomized Trial of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Monotherapy as a First Line Therapy in Patients With Unresectable Recurrent, or Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC) Which is Positive for Human Papilloma Virus 16 (HPV16+) and Expresses PD-L1",
"has_exemption": false,
"start_date": "2021-01-07",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Biontech SE",
"sponsor_slug": "biontech-se",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04822337",
"publication_url": "https://clinicaltrials.gov/study/NCT04822337",
"title": "A Phase I/II Study of Carfilzomib, Lenalidomide, Dexamethasone and the Anti-B-Cell Maturation Antigen (BCMA) Antibody Drug Conjugate Belantamab Mafodotin in Multiple Myeloma",
"has_exemption": false,
"start_date": "2021-05-19",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04770870",
"publication_url": "https://clinicaltrials.gov/study/NCT04770870",
"title": "Post Approval Study 2: Hintermann Series H3 Total Ankle Replacement System",
"has_exemption": false,
"start_date": "2022-02-01",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "DT MedTech, LLC",
"sponsor_slug": "dt-medtech-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05362760",
"publication_url": "https://clinicaltrials.gov/study/NCT05362760",
"title": "Combination of Abemaciclib and Endocrine Therapy in Hormone Receptor Positive HER2 Negative Locally Advanced or Metastatic Breast Cancer With Focus on Digital Side Effect Management. The MINERVA Trial - A Phase IV Trial",
"has_exemption": false,
"start_date": "2022-04-27",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Prof. Wolfgang Janni",
"sponsor_slug": "prof-wolfgang-janni",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05484115",
"publication_url": "https://clinicaltrials.gov/study/NCT05484115",
"title": "Randomized Controlled Clinical Trial on the Application of Heli-FX EndoAnchors in Conjunction With the Endurant II/IIs Endograft in Infrarenal Aortic Aneurysms With a Wide Infrarenal Neck (HERCULES Trial)",
"has_exemption": false,
"start_date": "2023-05-26",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Rijnstate Hospital",
"sponsor_slug": "rijnstate-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05701241",
"publication_url": "https://clinicaltrials.gov/study/NCT05701241",
"title": "Continuing Somatostatin Analogues Upon Progression in Neuroendocrine Tumour pAtients - The SAUNA Trial",
"has_exemption": false,
"start_date": "2023-06-28",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University Hospital, Antwerp",
"sponsor_slug": "university-hospital-antwerp",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05995353",
"publication_url": "https://clinicaltrials.gov/study/NCT05995353",
"title": "A Phase 3, Multi-Center Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Risankizumab With Open-Label Induction, Randomized Double-Blind Maintenance, and Long-Term Extension Periods in Pediatric Subjects (2 to < 18 Years of Age) With Moderately to Severely Active Crohn's Disease",
"has_exemption": false,
"start_date": "2023-12-11",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06372145",
"publication_url": "https://clinicaltrials.gov/study/NCT06372145",
"title": "An Interventional, Phase 3 Extension Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Relapsing Multiple Sclerosis, Primary Progressive Multiple Sclerosis, or Nonrelapsing Secondary Progressive Multiple Sclerosis",
"has_exemption": false,
"start_date": "2024-04-16",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06194799",
"publication_url": "https://clinicaltrials.gov/study/NCT06194799",
"title": "A 52-Week, Open-Label Extension Study of ACP-204 in Adults With Alzheimer's Disease Psychosis",
"has_exemption": false,
"start_date": "2024-04-23",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "ACADIA Pharmaceuticals Inc.",
"sponsor_slug": "acadia-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06029270",
"publication_url": "https://clinicaltrials.gov/study/NCT06029270",
"title": "A Randomized Phase II Study of Nivolumab Versus Nivolumab and BMS-986016 (Relatlimab) as Maintenance Treatment After First-Line Treatment With Platinum-Gemcitabine-Nivolumab for Patients With Epstein-Barr Virus-Associated Recurrent/Metastatic Nasopharyngeal Carcinoma (REMAIN)",
"has_exemption": false,
"start_date": "2024-07-15",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06512064",
"publication_url": "https://clinicaltrials.gov/study/NCT06512064",
"title": "Advancing Telemedicine in Pulmonology: Acoustic-waveform Respiratory Evaluation (AWARE) Via Sensing and Machine Learning on Smartphones",
"has_exemption": false,
"start_date": "2024-07-23",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05563766",
"publication_url": "https://clinicaltrials.gov/study/NCT05563766",
"title": "A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer",
"has_exemption": false,
"start_date": "2024-10-01",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06653153",
"publication_url": "https://clinicaltrials.gov/study/NCT06653153",
"title": "A Study of Remternetug Versus Placebo in Early Alzheimer's Disease Participants at Risk for Cognitive and Functional Decline",
"has_exemption": false,
"start_date": "2024-10-24",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06246799",
"publication_url": "https://clinicaltrials.gov/study/NCT06246799",
"title": "Comparative Effectiveness of Two Initial Combination Therapies in Patients With New Onset Diabetes",
"has_exemption": false,
"start_date": "2024-11-07",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center at San Antonio",
"sponsor_slug": "the-university-of-texas-health-science-center-at-san-antonio",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06556563",
"publication_url": "https://clinicaltrials.gov/study/NCT06556563",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Optune® (TTFields, 200 kHz) Concomitant With Maintenance Temozolomide and Pembrolizumab Versus Optune® Concomitant With Maintenance Temozolomide and Placebo for the Treatment of Newly Diagnosed Glioblastoma (EF-41/KEYNOTE D58).",
"has_exemption": false,
"start_date": "2025-02-03",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "NovoCure GmbH",
"sponsor_slug": "novocure-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06932289",
"publication_url": "https://clinicaltrials.gov/study/NCT06932289",
"title": "Integrating Metabolic and Vascular Sensors to Monitor Cardiometabolic Disorders After Nutrition Interventions",
"has_exemption": false,
"start_date": "2025-05-01",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Greater Los Angeles Healthcare System",
"sponsor_slug": "va-greater-los-angeles-healthcare-system",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06754046",
"publication_url": "https://clinicaltrials.gov/study/NCT06754046",
"title": "BELIEVE Trial: Bulking vErsus sLing for Treating Stress Urinary IncontinEnce at the Time of Vaginal prolapsE Repair",
"has_exemption": false,
"start_date": "2025-05-01",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University Hospitals Cleveland Medical Center",
"sponsor_slug": "university-hospitals-cleveland-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06947083",
"publication_url": "https://clinicaltrials.gov/study/NCT06947083",
"title": "Phase II Study of Elranatamab as Maintenance Therapy Post Ciltacabtagene-autoleucel(Cilta-cel) in Patients With Clinical High Risk Relapsed Myeloma",
"has_exemption": false,
"start_date": "2025-05-27",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07033494",
"publication_url": "https://clinicaltrials.gov/study/NCT07033494",
"title": "A Phase 2 Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study to Evaluate the Efficacy and Safety of MK-2214 in Participants With Early Alzheimer's Disease",
"has_exemption": false,
"start_date": "2025-07-16",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06825390",
"publication_url": "https://clinicaltrials.gov/study/NCT06825390",
"title": "Mechanistic Clinical Trial of Auricular Stimulation and Cryogenic Auriculotherapy in Patients With Chronic Low-back Pain, Using Functional Near-infrared Spectroscopy and Magnetic Resonance Imaging",
"has_exemption": false,
"start_date": "2025-07-30",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Keith M Vogt",
"sponsor_slug": "keith-m-vogt",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07131475",
"publication_url": "https://clinicaltrials.gov/study/NCT07131475",
"title": "ReBlast Precision (Precision Biomarkers to Detect Brain Injury in Active-Duty United States Special Operations Forces With Repeated Blast Exposure)",
"has_exemption": false,
"start_date": "2025-10-14",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07210255",
"publication_url": "https://clinicaltrials.gov/study/NCT07210255",
"title": "A Randomized Controlled Multi-site Trial Evaluating SAINT for Postpartum Depression",
"has_exemption": false,
"start_date": "2025-11-01",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Magnus Medical",
"sponsor_slug": "magnus-medical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06008717",
"publication_url": "https://clinicaltrials.gov/study/NCT06008717",
"title": "A Prospective, Randomized Feasibility Clinical Trial Evaluating Bilateral Stimulation of the Dorsolateral Region of the Subthalamic Nucleus Receiving Hyperdirect (M1/SMA) Input in Subjects With Early-Stage Parkinson's Disease",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Mallory Hacker",
"sponsor_slug": "mallory-hacker",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06402955",
"publication_url": "https://clinicaltrials.gov/study/NCT06402955",
"title": "Identifying the Neural Basis of Depression in Parkinson's Disease",
"has_exemption": false,
"start_date": "2025-12-01",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07298993",
"publication_url": "https://clinicaltrials.gov/study/NCT07298993",
"title": "Determining Evidence in a Placebo-Controlled, Randomized Experiment Studying Continuation vs. Removal of Inessential Beta-Blockers in Elders With Heart Failure With Preserved Ejection Fraction (DEPRESCRIBE-HFpEF)",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Weill Medical College of Cornell University",
"sponsor_slug": "weill-medical-college-of-cornell-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03176186",
"publication_url": "https://clinicaltrials.gov/study/NCT03176186",
"title": "XePOHCAS - Xenon by Inhalation for Post Out of Hospital Cardiac Arrest Syndrome",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Invero Pharma, Inc.",
"sponsor_slug": "invero-pharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06835504",
"publication_url": "https://clinicaltrials.gov/study/NCT06835504",
"title": "Efficacy of Intravenous Sub-Dissociative Ketamine Versus Intravenous Morphine in Children With Acute Pain",
"has_exemption": false,
"start_date": "2026-05-01",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Columbia University",
"sponsor_slug": "columbia-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07153055",
"publication_url": "https://clinicaltrials.gov/study/NCT07153055",
"title": "Phase I/II Trial of Lurbinectedin With Osimertinib in Transformed Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2026-05-31",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Misty Shields",
"sponsor_slug": "misty-shields",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03520751",
"publication_url": "https://clinicaltrials.gov/study/NCT03520751",
"title": "Phase I/IIa Trial Evaluating scAAV1.tMCK.NTF3 for Treatment of Charcot-Marie-Tooth Neuropathy Type 1A (CMT1A)",
"has_exemption": false,
"start_date": "2027-04-30",
"completion_date": "2029-04-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Nationwide Children's Hospital",
"sponsor_slug": "nationwide-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05556902",
"publication_url": "https://clinicaltrials.gov/study/NCT05556902",
"title": "Therapeutic Mechanisms of Epidural Spinal Cord Stimulation",
"has_exemption": false,
"start_date": "2022-08-02",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Alabama at Birmingham",
"sponsor_slug": "university-of-alabama-at-birmingham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06345963",
"publication_url": "https://clinicaltrials.gov/study/NCT06345963",
"title": "Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 1)",
"has_exemption": false,
"start_date": "2024-05-21",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06327100",
"publication_url": "https://clinicaltrials.gov/study/NCT06327100",
"title": "Open Label Phase 2 Study of Tasquinimod in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (Post-PV MF), or Post-Essential Thrombocytosis Myelofibrosis (Post-ET MF)",
"has_exemption": false,
"start_date": "2024-08-01",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06494111",
"publication_url": "https://clinicaltrials.gov/study/NCT06494111",
"title": "Systemic Therapy of Open-label Prophylactic Pravastatin or Pentoxifylline/Tocopherol Prevention of Lymphedema Advancing to Eventual Fibrosis: an Interventional Registry-embedded Bayesian Randomized Trial for Radiation Sequelae (STOP4-LATE-FIBROSE)",
"has_exemption": false,
"start_date": "2025-02-13",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06897930",
"publication_url": "https://clinicaltrials.gov/study/NCT06897930",
"title": "A Phase 1b/2 Study of AZD0120, a Chimeric Antigen Receptor T-cell (CAR T) Therapy Targeting CD19 and B-cell Maturation Antigen (BCMA) in Subjects With Refractory Systemic Lupus Erythematosus (SLE)",
"has_exemption": false,
"start_date": "2025-04-21",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06909110",
"publication_url": "https://clinicaltrials.gov/study/NCT06909110",
"title": "Viral Specific T-Lymphocytes by Cytokine Capture System (CCS) to Treat Infection With Adenovirus, Cytomegalovirus or Epstein-Barr Virus After Hematopoietic Cell Transplantation or Solid Organ Transplantation and in Patients With Compromised Immunity",
"has_exemption": false,
"start_date": "2025-04-30",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Jessie L. Alexander",
"sponsor_slug": "jessie-l-alexander",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06261840",
"publication_url": "https://clinicaltrials.gov/study/NCT06261840",
"title": "Refining Treatment Options for Trichomonas Vaginalis Infection in Women and Men: A Comparative Analysis of Oral Multi-Dose Metronidazole and Single-Dose Secnidazole",
"has_exemption": false,
"start_date": "2025-05-06",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Tulane University",
"sponsor_slug": "tulane-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06961916",
"publication_url": "https://clinicaltrials.gov/study/NCT06961916",
"title": "Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 2)",
"has_exemption": false,
"start_date": "2025-06-03",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06999577",
"publication_url": "https://clinicaltrials.gov/study/NCT06999577",
"title": "The MVP Trial: A Randomized Controlled Trial of Mechanism Guided vs PPI Strategy for Laryngopharyngeal Reflux",
"has_exemption": false,
"start_date": "2025-06-04",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Diego",
"sponsor_slug": "university-of-california-san-diego",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06501820",
"publication_url": "https://clinicaltrials.gov/study/NCT06501820",
"title": "Neural Control of Gait & Navigation in ADRD, Aim 3 Clinical Trial",
"has_exemption": false,
"start_date": "2025-11-13",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Florida",
"sponsor_slug": "university-of-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07024706",
"publication_url": "https://clinicaltrials.gov/study/NCT07024706",
"title": "The MAVRiC Study: A Phase II Study of Disease Risk Mutation Guided Finite Duration Acalabrutinib Plus Venetoclax for Relapse in CLL/SLL After First-line Finite Covalent BTKi Plus BCL2i Combination, With or Without Obinutuzumab",
"has_exemption": false,
"start_date": "2026-01-30",
"completion_date": "2029-05-01",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07197866",
"publication_url": "https://clinicaltrials.gov/study/NCT07197866",
"title": "An Open-Label Extension, Multi-Centered, Phase 2 Trial to Describe the Safety and Efficacy of TEV-56286 (Emrusolmin) in Participants With Multiple System Atrophy",
"has_exemption": false,
"start_date": "2025-09-30",
"completion_date": "2029-05-03",
"has_results": false,
"results_due": false,
"sponsor_name": "Teva Branded Pharmaceutical Products R&D LLC",
"sponsor_slug": "teva-branded-pharmaceutical-products-rd-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07076121",
"publication_url": "https://clinicaltrials.gov/study/NCT07076121",
"title": "A Randomized, Phase 2/3 Study Comparing BMS-986504 in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma Harboring Homozygous MTAP Deletion",
"has_exemption": false,
"start_date": "2025-10-23",
"completion_date": "2029-05-03",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07318610",
"publication_url": "https://clinicaltrials.gov/study/NCT07318610",
"title": "A Master Protocol for a Phase 3, Multicenter, Randomized Study to Evaluate the Efficacy and Safety of REGN7508 and REGN9933, Monoclonal Antibodies Against Factor XI, in Participants With Recent Lower Extremity Revascularization for Symptomatic Peripheral Artery Disease (ROXI-PALISADE)",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-05-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06976476",
"publication_url": "https://clinicaltrials.gov/study/NCT06976476",
"title": "Prospective Randomized Phase II Study Evaluating Efficacy and Safety of IgPro20 as Infection Prophylaxis in Patients With Multiple Myeloma and Hypogammaglobulinemia Receiving Therapy With a Bispecific Monoclonal Antibody (BsAbs)",
"has_exemption": false,
"start_date": "2025-05-08",
"completion_date": "2029-05-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06627647",
"publication_url": "https://clinicaltrials.gov/study/NCT06627647",
"title": "A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab in Combination With Platinum-based Chemotherapy for the First-line Treatment of Patients With Metastatic Non-squamous Non-small Cell Lung Cancer Whose Tumors Express PD-L1 (ARTEMIDE-Lung03)",
"has_exemption": false,
"start_date": "2024-11-27",
"completion_date": "2029-05-10",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06630416",
"publication_url": "https://clinicaltrials.gov/study/NCT06630416",
"title": "A Phase II Trial to Evaluate Pemetrexed Response in Relation to Tumor Alterations of Gene Status in Patients With Previously Treated Metastatic Urothelial Carcinoma and Other Solid Tumors",
"has_exemption": false,
"start_date": "2024-11-27",
"completion_date": "2029-05-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07252232",
"publication_url": "https://clinicaltrials.gov/study/NCT07252232",
"title": "RASolute 304: A Phase 3 Multicenter, Open-label, Randomized, 2-Arm Study of Adjuvant Daraxonrasib Versus Standard of Care Observation Following Completion of Neoadjuvant and/or Adjuvant Chemotherapy in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)",
"has_exemption": false,
"start_date": "2025-12-15",
"completion_date": "2029-05-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Revolution Medicines, Inc.",
"sponsor_slug": "revolution-medicines-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07184931",
"publication_url": "https://clinicaltrials.gov/study/NCT07184931",
"title": "A Multicenter, Multinational, Randomized, Double-blind, Placebo-controlled Phase 3, Induction Study to Evaluate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease",
"has_exemption": false,
"start_date": "2025-10-01",
"completion_date": "2029-05-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07201922",
"publication_url": "https://clinicaltrials.gov/study/NCT07201922",
"title": "A Double Blind, Randomized, Placebo-controlled Exploratory Trial to Investigate the Efficacy and Safety of Nerandomilast Over 24 Months When Administered in Individuals With Interstitial Lung Abnormalities and a Family History of Pulmonary Fibrosis to Reduce the Risk of Worsening (DROP-FPF)",
"has_exemption": false,
"start_date": "2026-01-23",
"completion_date": "2029-05-14",
"has_results": false,
"results_due": false,
"sponsor_name": "Boehringer Ingelheim",
"sponsor_slug": "boehringer-ingelheim",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05564390",
"publication_url": "https://clinicaltrials.gov/study/NCT05564390",
"title": "Master Screening and Reassessment Protocol (MSRP) for the NCI MyeloMATCH Clinical Trials",
"has_exemption": false,
"start_date": "2024-06-18",
"completion_date": "2029-05-15",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06317649",
"publication_url": "https://clinicaltrials.gov/study/NCT06317649",
"title": "A Randomized Phase II Study of Venetoclax and HMA-Based Therapies for the Treatment of Older and Unfit Adults With Newly Diagnosed FLT3-Mutated Acute Myeloid Leukemia (AML): A MyeloMATCH Treatment Trial",
"has_exemption": false,
"start_date": "2024-09-27",
"completion_date": "2029-05-15",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05458297",
"publication_url": "https://clinicaltrials.gov/study/NCT05458297",
"title": "A Multicenter, Open-label, Phase 2 Basket Study to Evaluate the Safety and Efficacy of MK-2140 as a Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (waveLINE-006)",
"has_exemption": false,
"start_date": "2022-07-21",
"completion_date": "2029-05-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05878717",
"publication_url": "https://clinicaltrials.gov/study/NCT05878717",
"title": "A Phase 2/3, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate The Efficacy And Safety of Belimumab Administered Subcutaneously in Adults With Systemic Sclerosis Associated Interstitial Lung Disease (SSC-ILD)",
"has_exemption": false,
"start_date": "2023-09-13",
"completion_date": "2029-05-17",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06662448",
"publication_url": "https://clinicaltrials.gov/study/NCT06662448",
"title": "An Open-Label Study to Evaluate the Efficacy and Feasibility of Home-Based Repetitive Transorbital Alternating Current Stimulation for Optic Neuropathies",
"has_exemption": false,
"start_date": "2024-11-18",
"completion_date": "2029-05-18",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06430788",
"publication_url": "https://clinicaltrials.gov/study/NCT06430788",
"title": "Phase 2a/2b Study Emapalumab: A Window of Opportunity in Pediatric Aplastic Anemia",
"has_exemption": false,
"start_date": "2024-05-21",
"completion_date": "2029-05-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07006506",
"publication_url": "https://clinicaltrials.gov/study/NCT07006506",
"title": "Phase II Open Label Prospective Nonrandomized Trial of Belumosudil for Switch-Maintenance Prophylaxis of Graft-versus-Host Disease in Allogeneic Hematopoietic Cell Transplantation",
"has_exemption": false,
"start_date": "2025-05-21",
"completion_date": "2029-05-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06667076",
"publication_url": "https://clinicaltrials.gov/study/NCT06667076",
"title": "A Phase 2b, Open-Label, Two-cohort Study of Subcutaneous Amivantamab in Combination With Lazertinib as First-Line Treatment, or Subcutaneous Amivantamab in Combination With Platinum-Based Chemotherapy as Second-line Treatment, for Common EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2024-12-16",
"completion_date": "2029-05-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07203001",
"publication_url": "https://clinicaltrials.gov/study/NCT07203001",
"title": "An Open-label Phase II Trial to Evaluate the Clinical Efficacy, Safety and Tolerability of MAS825 in Pediatric and Adult Participants With Still's Disease",
"has_exemption": false,
"start_date": "2025-11-03",
"completion_date": "2029-05-24",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03965234",
"publication_url": "https://clinicaltrials.gov/study/NCT03965234",
"title": "Phase I/ II Study of Pulmonary Suffusion to Control Minimal Residual Disease in Resectable or Ablatable Sarcoma or Colorectal Pulmonary Metastases",
"has_exemption": false,
"start_date": "2020-07-16",
"completion_date": "2029-05-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Roswell Park Cancer Institute",
"sponsor_slug": "roswell-park-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05285826",
"publication_url": "https://clinicaltrials.gov/study/NCT05285826",
"title": "A Phase 3 Randomized, Double-Blind, Placebo-Controlled Clinical Study to Evaluate the Efficacy, Immunogenicity, and Safety of V503, a 9-Valent Human Papillomavirus (HPV) Vaccine, in Chinese Males 20 to 45 Years of Age",
"has_exemption": false,
"start_date": "2022-02-18",
"completion_date": "2029-05-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07287982",
"publication_url": "https://clinicaltrials.gov/study/NCT07287982",
"title": "A Phase 2 Double-Blinded, Randomized, Placebo-Controlled Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy",
"has_exemption": false,
"start_date": "2025-12-19",
"completion_date": "2029-05-28",
"has_results": false,
"results_due": false,
"sponsor_name": "argenx",
"sponsor_slug": "argenx",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04776252",
"publication_url": "https://clinicaltrials.gov/study/NCT04776252",
"title": "A Phase 3 Open-label Rollover Clinical Study of Doravirine/Islatravir (DOR/ISL) Once-daily for the Treatment of HIV-1 Infection in Participants Who Previously Received DOR/ISL in a Phase 2 or Phase 3 DOR/ISL Clinical Study",
"has_exemption": false,
"start_date": "2021-09-15",
"completion_date": "2029-05-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04802759",
"publication_url": "https://clinicaltrials.gov/study/NCT04802759",
"title": "A Phase Ib/II, Open-Label, Multicenter, Randomized Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Breast Cancer (MORPHEUS-BREAST CANCER)",
"has_exemption": false,
"start_date": "2021-06-22",
"completion_date": "2029-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06319248",
"publication_url": "https://clinicaltrials.gov/study/NCT06319248",
"title": "MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) Trial",
"has_exemption": false,
"start_date": "2024-05-14",
"completion_date": "2029-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06599099",
"publication_url": "https://clinicaltrials.gov/study/NCT06599099",
"title": "Building Mood State Classifiers to Inform Deep Brain Stimulation of Treatment-Resistant Bipolar Depression",
"has_exemption": false,
"start_date": "2025-01-01",
"completion_date": "2029-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Wayne Goodman MD",
"sponsor_slug": "wayne-goodman-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07279558",
"publication_url": "https://clinicaltrials.gov/study/NCT07279558",
"title": "Effects of Full-spectrum Cannabidiol on Alcohol Consumption and Alcohol Use Disorder Phenotypes: Implications for Precision Medicine",
"has_exemption": false,
"start_date": "2026-02-01",
"completion_date": "2029-05-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03705585",
"publication_url": "https://clinicaltrials.gov/study/NCT03705585",
"title": "CVD 38000: Immunity, Microbiome, Epigenetics, and a Systems Biology Approach to the Study of Responses to Vaccination With Typhoid and/or Cholera",
"has_exemption": false,
"start_date": "2018-11-05",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Maryland, Baltimore",
"sponsor_slug": "university-of-maryland-baltimore",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03495427",
"publication_url": "https://clinicaltrials.gov/study/NCT03495427",
"title": "The Utility of PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men With High GC Decipher® Test Scores: A Sub-aim of the VANDAAM Study (MCC #18523)",
"has_exemption": false,
"start_date": "2019-12-18",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04339764",
"publication_url": "https://clinicaltrials.gov/study/NCT04339764",
"title": "A Phase I/IIa Trial for Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration",
"has_exemption": false,
"start_date": "2020-09-23",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Eye Institute (NEI)",
"sponsor_slug": "national-eye-institute-nei",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05318573",
"publication_url": "https://clinicaltrials.gov/study/NCT05318573",
"title": "A Phase 2a Study With Safety Run-in to Evaluate the Safety, Tolerability, and Preliminary Efficacy of FF-10832 Monotherapy or in Combination With Pembrolizumab in Patients With Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2022-06-01",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Fujifilm Pharmaceuticals U.S.A., Inc.",
"sponsor_slug": "fujifilm-pharmaceuticals-usa-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05533775",
"publication_url": "https://clinicaltrials.gov/study/NCT05533775",
"title": "A Phase I/II, Open-Label, Single-Arm, Two-Part Trial to Evaluate Safety, Tolerability, Pharmacokinetics, and Anti-Tumor Activity of Glofitamab in Monotherapy and in Combination With Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma",
"has_exemption": false,
"start_date": "2022-11-16",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06016842",
"publication_url": "https://clinicaltrials.gov/study/NCT06016842",
"title": "A Phase III Randomised, Parallel-Group, Double-Blind, Placebo-Controlled, Two-Arm Study to Evaluate the Efficacy and Safety of Elafibranor 80 mg on Long-Term Clinical Outcomes in Adult Participants With Primary Biliary Cholangitis (PBC)",
"has_exemption": false,
"start_date": "2023-08-31",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ipsen",
"sponsor_slug": "ipsen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05537220",
"publication_url": "https://clinicaltrials.gov/study/NCT05537220",
"title": "NAC Attack, A Phase III, Multicenter, Randomized, Parallel, Double Masked, Placebo-Controlled Study Evaluating the Efficacy and Safety of Oral N-Acetylcysteine in Patients With Retinitis Pigmentosa",
"has_exemption": false,
"start_date": "2023-10-11",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06420297",
"publication_url": "https://clinicaltrials.gov/study/NCT06420297",
"title": "A Long-term, Open-label Extension Study of Carbetocin Nasal Spray for the Treatment of Hyperphagia in Prader-Willi Syndrome",
"has_exemption": false,
"start_date": "2024-03-11",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ACADIA Pharmaceuticals Inc.",
"sponsor_slug": "acadia-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05940207",
"publication_url": "https://clinicaltrials.gov/study/NCT05940207",
"title": "Safety Testing of Hydrogen Peroxide-Generating e-Bandage on Normal Human Skin",
"has_exemption": false,
"start_date": "2024-03-27",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06545136",
"publication_url": "https://clinicaltrials.gov/study/NCT06545136",
"title": "A Multicenter, Long-term, Follow-up Study to Investigate the Safety and Durability of Response Following Dosing of an Adeno-associated Viral Vector (FLT201) in Subjects With Gaucher Disease (GALILEO-2)",
"has_exemption": false,
"start_date": "2024-05-13",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Spur Therapeutics",
"sponsor_slug": "spur-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06295731",
"publication_url": "https://clinicaltrials.gov/study/NCT06295731",
"title": "A Phase 2/3, Randomized Study of INBRX-106 Combined With Pembrolizumab Versus Pembrolizumab as First Line Treatment for Patients With Recurrent or Metastatic (R/M) Head and Neck Squamous Cell Carcinoma (HNSCC) Expressing PD-L1 (CPS ≥20) (HexAgon-HN)",
"has_exemption": false,
"start_date": "2024-05-14",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Inhibrx Biosciences, Inc",
"sponsor_slug": "inhibrx-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06378866",
"publication_url": "https://clinicaltrials.gov/study/NCT06378866",
"title": "MC230502 Dynamic Investigator Initiated Enterprise (DIVINE) in Prostate Cancer",
"has_exemption": false,
"start_date": "2024-06-03",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06374875",
"publication_url": "https://clinicaltrials.gov/study/NCT06374875",
"title": "A Prospective Multicenter International Randomized Controlled Trial Comparing Surgical and Medical Therapies in the Treatment of Advanced Metabolic Dysfunction Associated Steatohepatitis",
"has_exemption": false,
"start_date": "2024-07-11",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ali Aminian",
"sponsor_slug": "ali-aminian",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06485206",
"publication_url": "https://clinicaltrials.gov/study/NCT06485206",
"title": "A Clinical Investigation Evaluating Safety and Effectiveness of Primary Hybrid Construct of Mobi-C and ACDF in the Treatment of Two-level Symptomatic Degenerative Disc Disease in the Cervical Spine.",
"has_exemption": false,
"start_date": "2024-09-01",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Highridge Medical",
"sponsor_slug": "highridge-medical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06789848",
"publication_url": "https://clinicaltrials.gov/study/NCT06789848",
"title": "Phase II Basket Trial of Ligufalimab (AK117) and Cadonilimab (AK104) in Advanced Hepatobiliary Cancers",
"has_exemption": false,
"start_date": "2025-02-18",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06682442",
"publication_url": "https://clinicaltrials.gov/study/NCT06682442",
"title": "Induction Chemotherapy Response-Guided Radiation for EBV-Associated Nasopharyngeal Carcinoma",
"has_exemption": false,
"start_date": "2025-03-18",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06604520",
"publication_url": "https://clinicaltrials.gov/study/NCT06604520",
"title": "Functional Neuroimaging to Examine Affective Symptoms and Cognition in Frontotemporal Dementia",
"has_exemption": false,
"start_date": "2025-03-20",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06890598",
"publication_url": "https://clinicaltrials.gov/study/NCT06890598",
"title": "A Phase 3, Multicenter, Double-Blind, Placebo-controlled Study Assessing the Efficacy and Safety of Olomorasib in Combination With Standard of Care Immunotherapy in Participants With Resected or Unresectable KRAS G12C-Mutant, Non-Small Cell Lung Cancer - SUNRAY-02",
"has_exemption": false,
"start_date": "2025-03-27",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06966401",
"publication_url": "https://clinicaltrials.gov/study/NCT06966401",
"title": "A Long-Term, Open-Label Study to Assess the Safety and Tolerability of NBI-1065845 as Adjunctive Treatment in Subjects With Major Depressive Disorder (MDD)",
"has_exemption": false,
"start_date": "2025-04-16",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Neurocrine Biosciences",
"sponsor_slug": "neurocrine-biosciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06768905",
"publication_url": "https://clinicaltrials.gov/study/NCT06768905",
"title": "IOMAB-ACT: A Phase Ib/II Multi-institutional Study of 131 I-Apamistamab Followed by CD19-Targeted CAR-T Cell Therapy for Patients With Relapsed or Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL)",
"has_exemption": false,
"start_date": "2025-04-25",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06585969",
"publication_url": "https://clinicaltrials.gov/study/NCT06585969",
"title": "A Randomised Trial Comparing Trastuzumab Deruxtecan to CDK4/6 Inhibitors in Non-luminal A, ER-positive/HER2-low Metastatic Breast Cancer",
"has_exemption": false,
"start_date": "2025-05-01",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Danish Breast Cancer Cooperative Group",
"sponsor_slug": "danish-breast-cancer-cooperative-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06812715",
"publication_url": "https://clinicaltrials.gov/study/NCT06812715",
"title": "Clonal Dynamics of Chronic Lymphocytic Leukaemia Treated With Pirtobrutinib After Previous Treatment With Zanubrutinib",
"has_exemption": false,
"start_date": "2025-05-05",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Peter MacCallum Cancer Centre, Australia",
"sponsor_slug": "peter-maccallum-cancer-centre-australia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06512194",
"publication_url": "https://clinicaltrials.gov/study/NCT06512194",
"title": "An Investigation of Strategies to Understand and Optimize the Antidepressant Effects of Psilocybin (The OPTIMIZE Study)",
"has_exemption": false,
"start_date": "2025-05-13",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Charles Raison",
"sponsor_slug": "charles-raison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06716112",
"publication_url": "https://clinicaltrials.gov/study/NCT06716112",
"title": "Mechanisms of Paired Vagus Nerve Stimulation (VNS) in Chronic Stroke: a Randomized, Blinded, Sham-controlled, Single-center Mechanistic Trial",
"has_exemption": false,
"start_date": "2025-07-15",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06349083",
"publication_url": "https://clinicaltrials.gov/study/NCT06349083",
"title": "Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for Alcohol Use Disorder",
"has_exemption": false,
"start_date": "2025-08-26",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06899165",
"publication_url": "https://clinicaltrials.gov/study/NCT06899165",
"title": "Processing Intergenerational Trauma With Psilocybin-Assisted Therapy",
"has_exemption": false,
"start_date": "2025-08-28",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Rachel Yehuda",
"sponsor_slug": "rachel-yehuda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06875128",
"publication_url": "https://clinicaltrials.gov/study/NCT06875128",
"title": "An Open-label, Randomized, Multi-Center Study to Evaluate the Efficacy and Safety of Induction Treatment With Melphalan/HDS Followed by Consolidation Treatment With Eribulin or Vinorelbine or Capecitabine Versus Eribulin or Vinorelbine or Capecitabine Alone in Patients With Metastatic Breast Cancer With Liver Dominant Disease",
"has_exemption": false,
"start_date": "2025-09-30",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Delcath Systems Inc.",
"sponsor_slug": "delcath-systems-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07174583",
"publication_url": "https://clinicaltrials.gov/study/NCT07174583",
"title": "A Multicenter Study Evaluating the Safety, Efficacy, and Pharmacokinetics of IDE849 in Patients With DLL3-Expressing Tumors Including Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2025-10-14",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "IDEAYA Biosciences",
"sponsor_slug": "ideaya-biosciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07218796",
"publication_url": "https://clinicaltrials.gov/study/NCT07218796",
"title": "A Prospective, Multicenter, Randomized, Masked, Controlled Study to Evaluate the Safety and Efficacy of the Bimatoprost Implant System (78 mcg) Used in Combination With the SpyGlass IOL Compared to Timolol Maleate Ophthalmic Solution, USP, 0.5%,",
"has_exemption": false,
"start_date": "2025-10-28",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "SpyGlass Pharma, Inc.",
"sponsor_slug": "spyglass-pharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06954129",
"publication_url": "https://clinicaltrials.gov/study/NCT06954129",
"title": "Markers of Nephrotoxicity During Treatment With Antibiotic Combinations: A Pragmatic Clinical Trial",
"has_exemption": false,
"start_date": "2025-10-31",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07155174",
"publication_url": "https://clinicaltrials.gov/study/NCT07155174",
"title": "A Phase 2 Randomized, Open Label, Multicenter Study to Evaluate the Optimal Dose, Safety, and Efficacy of ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Subjects With Previously Untreated Extensive Stage Small Cell Lung Cancer (ES-SCLC)",
"has_exemption": false,
"start_date": "2025-11-25",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07174336",
"publication_url": "https://clinicaltrials.gov/study/NCT07174336",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of LY4064809 Combined With a CDK4/6 Inhibitor and Endocrine Therapy in Adults With HR+, HER2-Advanced Breast Cancer With a PIK3CA Mutation Who Received No Prior Treatment for Advanced Breast Cancer (PIKALO-2)",
"has_exemption": false,
"start_date": "2025-12-22",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06961357",
"publication_url": "https://clinicaltrials.gov/study/NCT06961357",
"title": "Phase I/II Clinical Trial of CD40L-augmented Tumor Infiltrating Lymphocytes (TIL) for Patients With Advanced Melanoma",
"has_exemption": false,
"start_date": "2026-01-01",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07285694",
"publication_url": "https://clinicaltrials.gov/study/NCT07285694",
"title": "An Open-label, Multicenter Phase 1/2 Study to Evaluate the Safety and Efficacy of AB-3028 in Patients With Castration Resistant Prostate Cancer (CRPC)",
"has_exemption": false,
"start_date": "2026-01-09",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Arsenal Biosciences, Inc.",
"sponsor_slug": "arsenal-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06773936",
"publication_url": "https://clinicaltrials.gov/study/NCT06773936",
"title": "A Phase II Trial of Asciminib, Dasatinib, Prednisone, and Blinatumomab for Participants With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia",
"has_exemption": false,
"start_date": "2026-03-15",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "SWOG Cancer Research Network",
"sponsor_slug": "swog-cancer-research-network",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07071935",
"publication_url": "https://clinicaltrials.gov/study/NCT07071935",
"title": "A Pilot Randomized Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06769854",
"publication_url": "https://clinicaltrials.gov/study/NCT06769854",
"title": "Defining the Safety and Efficacy of POSterIor Tibial NeRve StimulatiON in Children",
"has_exemption": false,
"start_date": "2027-04-01",
"completion_date": "2029-05-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Chi Dang Hornik",
"sponsor_slug": "chi-dang-hornik",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03258567",
"publication_url": "https://clinicaltrials.gov/study/NCT03258567",
"title": "Phase 2 Trial of Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-Hodgkin Lymphomas",
"has_exemption": false,
"start_date": "2018-04-26",
"completion_date": "2029-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06548061",
"publication_url": "https://clinicaltrials.gov/study/NCT06548061",
"title": "Single Center Observational Study Using Spinal Laser Interstitial Thermal Therapy (sLITT) in the Treatment of Spine Metastases and Tumors",
"has_exemption": false,
"start_date": "2024-05-16",
"completion_date": "2029-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Dartmouth-Hitchcock Medical Center",
"sponsor_slug": "dartmouth-hitchcock-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06978088",
"publication_url": "https://clinicaltrials.gov/study/NCT06978088",
"title": "A Multicenter Parallel 2 Cohort Phase 2 Study of LP-168 and Obinutuzumab for Previously Treated, and T474 Gatekeeper Mutant Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) and Variants of This",
"has_exemption": false,
"start_date": "2025-06-01",
"completion_date": "2029-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Zulfa Omer",
"sponsor_slug": "zulfa-omer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07129993",
"publication_url": "https://clinicaltrials.gov/study/NCT07129993",
"title": "A Randomized, Open-Label, Phase 2/3 Study of Datopotamab Deruxtecan (Dato-DXd) Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma (la/mUC) Who Progressed During or After Enfortumab Vedotin (EV) Plus Pembrolizumab Combination Treatment TROPION-Urothelial03 (TU03)",
"has_exemption": false,
"start_date": "2025-09-26",
"completion_date": "2029-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Daiichi Sankyo",
"sponsor_slug": "daiichi-sankyo",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06816927",
"publication_url": "https://clinicaltrials.gov/study/NCT06816927",
"title": "A Multi-Center, Randomized, Phase 2 Trial of Glioblastoma Immunotherapy Advancement With Nivolumab and Relatlimab (GIANT)",
"has_exemption": false,
"start_date": "2025-11-28",
"completion_date": "2029-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Duke University",
"sponsor_slug": "duke-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06944145",
"publication_url": "https://clinicaltrials.gov/study/NCT06944145",
"title": "A Phase 2b Randomized, Single-Center, Double Blind, Placebo Controlled, 2-Arm Study to Investigate Orally Administered Combination Therapies (5-alpha Reductase Inhibitor + Raloxifene) Compared With Monotherapy (5-alpha Reductase Inhibitor + Placebo) in Adult Patients With Benign Prostatic Hyperplasia (BPH)",
"has_exemption": false,
"start_date": "2025-12-03",
"completion_date": "2029-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Beth Israel Deaconess Medical Center",
"sponsor_slug": "beth-israel-deaconess-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05899764",
"publication_url": "https://clinicaltrials.gov/study/NCT05899764",
"title": "Epileptic Hippocampus in Alzheimer's Disease",
"has_exemption": false,
"start_date": "2026-01-01",
"completion_date": "2029-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Los Angeles",
"sponsor_slug": "university-of-california-los-angeles",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07099638",
"publication_url": "https://clinicaltrials.gov/study/NCT07099638",
"title": "Randomized Factorial Trial of Varenicline With Nicotine Lozenges and a Smartphone Medication Adherence Intervention to Promote Smoking Cessation",
"has_exemption": false,
"start_date": "2026-01-05",
"completion_date": "2029-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Oklahoma",
"sponsor_slug": "university-of-oklahoma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07356284",
"publication_url": "https://clinicaltrials.gov/study/NCT07356284",
"title": "Emergent Large Vessel Occlusion Endovascular Rescue Therapy With Underlying Intracranial Stenosis",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2029-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "ProMedica Health System",
"sponsor_slug": "promedica-health-system",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07361484",
"publication_url": "https://clinicaltrials.gov/study/NCT07361484",
"title": "A Global, Multicenter, Randomized, Double-blinded, Phase 3 Study of Docetaxel + Plinabulin Compared to Docetaxel + Placebo in Patients With Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer With EGFR, ALK, ROS, and RET Wild Type After Progressing on Prior Immunotherapy (Anti-PD-1/L1 Antibody) and Platinum-based Chemotherapy (DUBLIN-4)",
"has_exemption": false,
"start_date": "2026-06-01",
"completion_date": "2029-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "BeyondSpring Pharmaceuticals Inc.",
"sponsor_slug": "beyondspring-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07011758",
"publication_url": "https://clinicaltrials.gov/study/NCT07011758",
"title": "Dynamic Treatment Regimes for Personalized Opioid Use Disorder Care",
"has_exemption": false,
"start_date": "2028-07-01",
"completion_date": "2029-06-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06900595",
"publication_url": "https://clinicaltrials.gov/study/NCT06900595",
"title": "A Phase II Study of Cabozantinib in Combination With Cemiplimab (Cabo-Cemiplimab) Versus Cabozantinib Alone in Adolescents and Adults With Advanced Adrenocortical Cancer",
"has_exemption": false,
"start_date": "2026-07-19",
"completion_date": "2029-06-02",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04924075",
"publication_url": "https://clinicaltrials.gov/study/NCT04924075",
"title": "A Phase 2 Study to Evaluate the Efficacy and Safety of Belzutifan (MK-6482, Formerly PT2977) Monotherapy in Participants With Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Advanced Solid Tumors With HIF-2α Related Genetic Alterations",
"has_exemption": false,
"start_date": "2021-08-12",
"completion_date": "2029-06-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07286214",
"publication_url": "https://clinicaltrials.gov/study/NCT07286214",
"title": "A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Each of Two Dose Levels of Sarilumab in Adults With Early Polymyalgia Rheumatica",
"has_exemption": false,
"start_date": "2026-01-19",
"completion_date": "2029-06-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06632457",
"publication_url": "https://clinicaltrials.gov/study/NCT06632457",
"title": "A Phase III Double-blind, Randomised, Placebo-controlled Trial to Evaluate Liver-related Clinical Outcomes and Safety of Once Weekly Injected Survodutide in Participants With Compensated Non-alcoholic Steatohepatitis/Metabolic Dysfunction Associated Steatohepatitis (NASH/MASH) Cirrhosis",
"has_exemption": false,
"start_date": "2024-11-12",
"completion_date": "2029-06-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Boehringer Ingelheim",
"sponsor_slug": "boehringer-ingelheim",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06868290",
"publication_url": "https://clinicaltrials.gov/study/NCT06868290",
"title": "A Phase 2, Randomized, Open-label, Controlled Study to Evaluate the Efficacy and Safety of Rapcabtagene Autoleucel Versus Comparator in Participants With Severe Active Granulomatosis With Polyangiitis (GPA) or Microscopic Polyangiitis (MPA)",
"has_exemption": false,
"start_date": "2025-03-13",
"completion_date": "2029-06-07",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03307980",
"publication_url": "https://clinicaltrials.gov/study/NCT03307980",
"title": "A FACTOR IX (FIX) GENE TRANSFER, MULTI CENTER EVALUATION OF THE LONG TERM SAFETY AND EFFICACY STUDY OF PF 06838435 AND A DOSE ESCALATION SUBSTUDY IN INDIVIDUALS WITH HEMOPHILIA B",
"has_exemption": false,
"start_date": "2017-06-22",
"completion_date": "2029-06-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07218510",
"publication_url": "https://clinicaltrials.gov/study/NCT07218510",
"title": "A Phase 2 Study of Venetoclax + Obinutuzumab Followed by Epcoritamab in Previously Untreated Chronic Lymphocytic Leukemia/ Small Lymphocytic Lymphoma (LonGEVity)",
"has_exemption": false,
"start_date": "2026-01-09",
"completion_date": "2029-06-08",
"has_results": false,
"results_due": false,
"sponsor_name": "City of Hope Medical Center",
"sponsor_slug": "city-of-hope-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07084584",
"publication_url": "https://clinicaltrials.gov/study/NCT07084584",
"title": "A Phase 1/2, Open-label, Dose-Escalation and Dose-Expansion Cohort Study of GB3226 in Patients With Relapsed/Refractory Acute Myeloid Leukemia",
"has_exemption": false,
"start_date": "2026-06-10",
"completion_date": "2029-06-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Galecto Biotech AB",
"sponsor_slug": "galecto-biotech-ab",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07222761",
"publication_url": "https://clinicaltrials.gov/study/NCT07222761",
"title": "An Open-Label, Randomized Phase 3 Study of Linvoseltamab Monotherapy and Linvoseltamab Plus Carfilzomib Versus Standard of Care Combination Regimens in Patients With Relapsed/Refractory Multiple Myeloma",
"has_exemption": false,
"start_date": "2026-01-02",
"completion_date": "2029-06-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06914128",
"publication_url": "https://clinicaltrials.gov/study/NCT06914128",
"title": "A First-in-human Study to Evaluate the Safety, Tolerability and Pharmacokinetics, Pharmacodynamics and Preliminary Clinical Activity of BAY 3713372, a Novel 2nd Generation PRMT5 Inhibitor, in Participants With MTAP-deleted Solid Tumors.",
"has_exemption": false,
"start_date": "2025-03-21",
"completion_date": "2029-06-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Bayer",
"sponsor_slug": "bayer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04368702",
"publication_url": "https://clinicaltrials.gov/study/NCT04368702",
"title": "Clinical Onboard Utilization of Image Guided Radiation Therapy With Magnetic Resonance (CONFIRM): A Master Protocol",
"has_exemption": false,
"start_date": "2021-05-01",
"completion_date": "2029-06-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Brigham and Women's Hospital",
"sponsor_slug": "brigham-and-womens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07276399",
"publication_url": "https://clinicaltrials.gov/study/NCT07276399",
"title": "A Phase 3, Randomized, Open-Label, Multicenter Study of Amivantamab in Addition to Carboplatin and Pembrolizumab, Compared to Standard of Care Platinum and Pembrolizumab and 5-FU, in Participants With Treatment-Naïve Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma",
"has_exemption": false,
"start_date": "2025-12-03",
"completion_date": "2029-06-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03950232",
"publication_url": "https://clinicaltrials.gov/study/NCT03950232",
"title": "An Open-Label Extension Study of Etrasimod in Subjects With Moderately to Severely Active Ulcerative Colitis",
"has_exemption": false,
"start_date": "2019-09-05",
"completion_date": "2029-06-19",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07013747",
"publication_url": "https://clinicaltrials.gov/study/NCT07013747",
"title": "A Phase 1/2, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety, Efficacy and Immunogenicity of an Acne mRNA Vaccine Candidate in Participants With Mild Acne",
"has_exemption": false,
"start_date": "2025-07-03",
"completion_date": "2029-06-19",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi Pasteur, a Sanofi Company",
"sponsor_slug": "sanofi-pasteur-a-sanofi-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07042581",
"publication_url": "https://clinicaltrials.gov/study/NCT07042581",
"title": "Evaluation of Revaree Plus in Women With Breast Cancer",
"has_exemption": false,
"start_date": "2025-06-20",
"completion_date": "2029-06-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06477419",
"publication_url": "https://clinicaltrials.gov/study/NCT06477419",
"title": "Phase 2 Study of Sacituzumab Govitecan-hziy in Patients With Previously Treated Mesothelioma",
"has_exemption": false,
"start_date": "2024-06-21",
"completion_date": "2029-06-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06852222",
"publication_url": "https://clinicaltrials.gov/study/NCT06852222",
"title": "A Phase 3 Randomized, Double-Blind, Placebo-Controlled, Study of Bleximenib, Venetoclax and Azacitidine for the Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia Harboring KMT2A Rearrangements or NPM1 Mutations Who Are Ineligible for Intensive Chemotherapy",
"has_exemption": false,
"start_date": "2025-06-04",
"completion_date": "2029-06-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Janssen Research & Development, LLC",
"sponsor_slug": "janssen-research-development-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06937229",
"publication_url": "https://clinicaltrials.gov/study/NCT06937229",
"title": "A Phase 3, Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-3)",
"has_exemption": false,
"start_date": "2025-12-02",
"completion_date": "2029-06-22",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07228273",
"publication_url": "https://clinicaltrials.gov/study/NCT07228273",
"title": "A Phase II Randomized Clinical Trial of Venetoclax Combined With FLAG IDA Induction and Consolidation Compared to Standard of Care for Newly Diagnosed Patients With Acute Myeloid Leukemia",
"has_exemption": false,
"start_date": "2025-12-12",
"completion_date": "2029-06-24",
"has_results": false,
"results_due": false,
"sponsor_name": "OHSU Knight Cancer Institute",
"sponsor_slug": "ohsu-knight-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06033833",
"publication_url": "https://clinicaltrials.gov/study/NCT06033833",
"title": "A Long-term Extension Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Subcutaneous Amlitelimab in Adult Participants With Moderate-to-severe Asthma Who Completed Treatment Period of Previous Amlitelimab Asthma Clinical Study",
"has_exemption": false,
"start_date": "2023-09-05",
"completion_date": "2029-06-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06044337",
"publication_url": "https://clinicaltrials.gov/study/NCT06044337",
"title": "A Multicenter, Open-Label, Single-Arm, Phase 3, Long-Term Extension Study to Evaluate Continuous Safety and Efficacy of BIIB059 (Litifilimab) in Adult Participants With Active Subacute Cutaneous Lupus Erythematosus and/or Chronic Cutaneous Lupus Erythematosus With or Without Systemic Manifestations and Refractory and/or Intolerant to Antimalarial Therapy",
"has_exemption": false,
"start_date": "2023-10-03",
"completion_date": "2029-06-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Biogen",
"sponsor_slug": "biogen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07339423",
"publication_url": "https://clinicaltrials.gov/study/NCT07339423",
"title": "Efficacy and Safety of NNC0487-0111 s.c. Once-weekly in Participants With Obesity (AMAZE 1)",
"has_exemption": false,
"start_date": "2026-02-24",
"completion_date": "2029-06-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Novo Nordisk A/S",
"sponsor_slug": "novo-nordisk-as",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07207811",
"publication_url": "https://clinicaltrials.gov/study/NCT07207811",
"title": "CLEOPATTRA: Effects of NNC6019-0001 Versus Placebo on Cardiovascular Outcomes in Participants With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)",
"has_exemption": false,
"start_date": "2025-10-02",
"completion_date": "2029-06-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Novo Nordisk A/S",
"sponsor_slug": "novo-nordisk-as",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06573970",
"publication_url": "https://clinicaltrials.gov/study/NCT06573970",
"title": "Atomoxetine Effect on Attention, Executive Function, and Quality of Life in Veterans With Posttraumatic Stress Disorder",
"has_exemption": false,
"start_date": "2026-02-02",
"completion_date": "2029-06-29",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06820138",
"publication_url": "https://clinicaltrials.gov/study/NCT06820138",
"title": "Low Intensity Focused Ultrasound for Posttraumatic Stress Disorder",
"has_exemption": false,
"start_date": "2026-02-02",
"completion_date": "2029-06-29",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03887455",
"publication_url": "https://clinicaltrials.gov/study/NCT03887455",
"title": "A Placebo-Controlled, Double-Blind, Parallel-Group, 18-Month Study With an Open-Label Extension Phase to Confirm Safety and Efficacy of BAN2401 in Subjects With Early Alzheimer's Disease",
"has_exemption": false,
"start_date": "2019-03-27",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Eisai Inc.",
"sponsor_slug": "eisai-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04120493",
"publication_url": "https://clinicaltrials.gov/study/NCT04120493",
"title": "A Phase 1/2, Randomized, Double-Blind, Sham Control and Open-Label Study to Explore Safety, Tolerability, and Efficacy Signals of Multiple Doses of Striatally-Administered rAAV5-miHTT Total Huntingtin Gene (HTT) Lowering Therapy (AMT-130) in Early Manifest Huntington's Disease",
"has_exemption": false,
"start_date": "2019-09-06",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "UniQure Biopharma B.V.",
"sponsor_slug": "uniqure-biopharma-bv",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04296903",
"publication_url": "https://clinicaltrials.gov/study/NCT04296903",
"title": "Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)",
"has_exemption": false,
"start_date": "2020-05-31",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Apifix",
"sponsor_slug": "apifix",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04404660",
"publication_url": "https://clinicaltrials.gov/study/NCT04404660",
"title": "An Open-Label, Multi-Centre, Phase Ib/II Study Evaluating the Safety and Efficacy of AUTO1, a CAR T Cell Treatment Targeting CD19, in Adult Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia",
"has_exemption": false,
"start_date": "2020-06-03",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Autolus Limited",
"sponsor_slug": "autolus-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04298723",
"publication_url": "https://clinicaltrials.gov/study/NCT04298723",
"title": "Randomized Comparison of Interventional Closure of the Left Atrial Appendage Using a LAA Closure Device Versus Oral Anticoagulation Therapy in Patients With Non-valvular Atrial Fibrillation and Status Post Intracranial Bleeding.",
"has_exemption": false,
"start_date": "2020-06-16",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Jena University Hospital",
"sponsor_slug": "jena-university-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04293562",
"publication_url": "https://clinicaltrials.gov/study/NCT04293562",
"title": "A Phase 3 Randomized Trial for Patients With De Novo AML Comparing Standard Therapy Including Gemtuzumab Ozogamicin (GO) to CPX-351 With GO, and the Addition of the FLT3 Inhibitor Gilteritinib for Patients With FLT3 Mutations",
"has_exemption": false,
"start_date": "2020-07-21",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04559139",
"publication_url": "https://clinicaltrials.gov/study/NCT04559139",
"title": "Optimal Perioperative Therapy for Incidental Gallbladder Cancer (OPT-IN): A Randomized Phase II/III Trial",
"has_exemption": false,
"start_date": "2021-02-24",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "ECOG-ACRIN Cancer Research Group",
"sponsor_slug": "ecog-acrin-cancer-research-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04671667",
"publication_url": "https://clinicaltrials.gov/study/NCT04671667",
"title": "A Phase II Randomized Trial of Adjuvant Therapy With Pembrolizumab After Resection of Recurrent/Second Primary Head and Neck Squamous Cell Carcinoma With High Risk Features",
"has_exemption": false,
"start_date": "2021-04-27",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04889872",
"publication_url": "https://clinicaltrials.gov/study/NCT04889872",
"title": "The PROGRESS Trial: A Prospective, Randomized, Controlled Trial to Assess the Management of Moderate Aortic Stenosis by Clinical Surveillance or Transcatheter Aortic Valve Replacement",
"has_exemption": false,
"start_date": "2021-10-12",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Edwards Lifesciences",
"sponsor_slug": "edwards-lifesciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05268614",
"publication_url": "https://clinicaltrials.gov/study/NCT05268614",
"title": "Risk Adapted De-Intensification of Radio-Chemotherapy for Favorable Prognosis Oropharyngeal Squamous Cell Carcinoma Based on HPV Subtype and Plasma Circulating Free HPV DNA Level and Clearance Rate",
"has_exemption": false,
"start_date": "2022-05-16",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Florida",
"sponsor_slug": "university-of-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05650658",
"publication_url": "https://clinicaltrials.gov/study/NCT05650658",
"title": "Cardiac Resynchronization Therapy Using His/Left Bundle Branch Pacing vs Biventricular Pacing With a Left Ventricular Epicardial Lead in Patients With Heart Failure (HF) With Left Ventricular Ejection Fraction (LVEF)≤50% and With Either a Wide QRS Complex (>130 ms) or With/Anticipated >40% Pacing Randomized Clinical Trial",
"has_exemption": false,
"start_date": "2023-09-13",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Baylor College of Medicine",
"sponsor_slug": "baylor-college-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05609630",
"publication_url": "https://clinicaltrials.gov/study/NCT05609630",
"title": "A Multicenter, Randomized Open-Label Study to Assess the Efficacy, Safety, and Pharmacokinetics of Upadacitinib With a Tocilizumab Reference Arm in Subjects From 1 Year to Less Than 18 Years Old With Active Systemic Juvenile Idiopathic Arthritis",
"has_exemption": false,
"start_date": "2023-10-02",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05863195",
"publication_url": "https://clinicaltrials.gov/study/NCT05863195",
"title": "A Randomized Phase III Study of Systemic Therapy With or Without Hepatic Arterial Infusion for Unresectable Colorectal Liver Metastases: The PUMP Trial",
"has_exemption": false,
"start_date": "2023-10-19",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "ECOG-ACRIN Cancer Research Group",
"sponsor_slug": "ecog-acrin-cancer-research-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06397469",
"publication_url": "https://clinicaltrials.gov/study/NCT06397469",
"title": "Optimizing a Closed-loop Digital Meditation Intervention for Remediating Cognitive Decline and Reducing Stress in Older Adults",
"has_exemption": false,
"start_date": "2024-04-01",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06245889",
"publication_url": "https://clinicaltrials.gov/study/NCT06245889",
"title": "A Pilot Study of Neoadjuvant Response-Adapted Chemotherapy With Pembrolizumab in Patients With Stage 2 and 3 Triple Negative Breast Cancer to Determine Early PET and Biomarker Dynamics",
"has_exemption": false,
"start_date": "2024-05-01",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins",
"sponsor_slug": "sidney-kimmel-comprehensive-cancer-center-at-johns-hopkins",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06408181",
"publication_url": "https://clinicaltrials.gov/study/NCT06408181",
"title": "APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia",
"has_exemption": false,
"start_date": "2024-06-12",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Pennsylvania",
"sponsor_slug": "university-of-pennsylvania",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06513182",
"publication_url": "https://clinicaltrials.gov/study/NCT06513182",
"title": "Do Wound Protectors Reduce Contamination in Total Shoulder Arthroplasty? A Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2024-06-21",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Utah",
"sponsor_slug": "university-of-utah",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05711667",
"publication_url": "https://clinicaltrials.gov/study/NCT05711667",
"title": "Letermovir Prophylaxis for Cytomegalovirus in Pediatric Hematopoietic Cell Transplantation",
"has_exemption": false,
"start_date": "2024-07-11",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Oncology Group",
"sponsor_slug": "childrens-oncology-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06315738",
"publication_url": "https://clinicaltrials.gov/study/NCT06315738",
"title": "Randomized, Controlled, Phase 1-2 Open Label Study of ST266 IV Administration to Assess the Safety, Tolerability, and Preliminary Efficacy of ST266 in Infants With Necrotizing Enterocolitis",
"has_exemption": false,
"start_date": "2024-08-19",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Noveome Biotherapeutics, formerly Stemnion",
"sponsor_slug": "noveome-biotherapeutics-formerly-stemnion",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06486441",
"publication_url": "https://clinicaltrials.gov/study/NCT06486441",
"title": "A Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer Who Have Received Prior Platinum-based Chemotherapy and Anti-PD-1/PD-L1 Immunotherapy",
"has_exemption": false,
"start_date": "2024-08-28",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Gilead Sciences",
"sponsor_slug": "gilead-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06470243",
"publication_url": "https://clinicaltrials.gov/study/NCT06470243",
"title": "A Phase III Study of Cabazitaxel With or Without Carboplatin in Patients With Metastatic Castrate-Resistant Prostate Cancer (mCRPC), Stratified by Aggressive Variant Signature",
"has_exemption": false,
"start_date": "2024-11-27",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "SWOG Cancer Research Network",
"sponsor_slug": "swog-cancer-research-network",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06641414",
"publication_url": "https://clinicaltrials.gov/study/NCT06641414",
"title": "A Global Multicenter, Double-blind, Randomized, Registrational Phase 3 Study of Lisaftoclax (APG-2575) in Combination With Azacitidine (AZA) in Patients With Newly Diagnosed Higher Risk Myelodysplastic Syndrome (HR-MDS) (GLORA-4).",
"has_exemption": false,
"start_date": "2025-01-22",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Ascentage Pharma Group Inc.",
"sponsor_slug": "ascentage-pharma-group-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06721819",
"publication_url": "https://clinicaltrials.gov/study/NCT06721819",
"title": "The SCOPE Trial: Sleep, Cognition, and Pain Bundle Vs. ERAS-cardiac for Postoperative Delirium",
"has_exemption": false,
"start_date": "2025-02-01",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Beth Israel Deaconess Medical Center",
"sponsor_slug": "beth-israel-deaconess-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06582875",
"publication_url": "https://clinicaltrials.gov/study/NCT06582875",
"title": "Advancing ADPKD Treatment With GLP-1RA: A Study of Glucagon-Like Peptide-1 Receptor Agonists' Efficacy, Safety, and Mechanism",
"has_exemption": false,
"start_date": "2025-03-06",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06592586",
"publication_url": "https://clinicaltrials.gov/study/NCT06592586",
"title": "A Follow-up Trial to Assess the Persistence of the Immune Response to the Group B Streptococcus Vaccine (GBS-NN/NN2) After a Primary Vaccination of Healthy Pregnant Women, and to Assess Safety, Reactogenicity, and Immunogenicity of the GBS-NN/NN2 Vaccine When Administered During Follow-Up as a 1 Booster Dose During a New Pregnancy",
"has_exemption": false,
"start_date": "2025-03-07",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Minervax ApS",
"sponsor_slug": "minervax-aps",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06161974",
"publication_url": "https://clinicaltrials.gov/study/NCT06161974",
"title": "Phase 2 Study of Olutasidenib with Temozolomide As Maintenance Therapy in Pediatric and Young Adult Patients Newly Diagnosed with High-Grade Glioma (HGG), Including Diffuse Intrinsic Pontine Glioma (DIPG), Which Harbor IDH1 Mutations",
"has_exemption": false,
"start_date": "2025-03-31",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Rigel Pharmaceuticals",
"sponsor_slug": "rigel-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06231563",
"publication_url": "https://clinicaltrials.gov/study/NCT06231563",
"title": "Examining Ketamine Effects on Depression, Neuroplasticity, and Inflammation in Veterans With Parkinson's Disease",
"has_exemption": false,
"start_date": "2025-04-01",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06609369",
"publication_url": "https://clinicaltrials.gov/study/NCT06609369",
"title": "Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse",
"has_exemption": false,
"start_date": "2025-04-21",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06953674",
"publication_url": "https://clinicaltrials.gov/study/NCT06953674",
"title": "Saline vs. Balanced Crystalloid in Traumatic Brain Injury",
"has_exemption": false,
"start_date": "2025-06-01",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Louisville",
"sponsor_slug": "university-of-louisville",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06852469",
"publication_url": "https://clinicaltrials.gov/study/NCT06852469",
"title": "Individualized Computational Assessment of the Effects of GABA Receptor Modulation in Posttraumatic Stress Disorder",
"has_exemption": false,
"start_date": "2025-07-01",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06940609",
"publication_url": "https://clinicaltrials.gov/study/NCT06940609",
"title": "Magnetic Resonance Analysis of Neural Inflammatory Factors and External Stimulation (MANIFEST)",
"has_exemption": false,
"start_date": "2025-07-07",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of New Mexico",
"sponsor_slug": "university-of-new-mexico",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06943755",
"publication_url": "https://clinicaltrials.gov/study/NCT06943755",
"title": "A Phase 2/3, Multicenter, Randomized Open-Label Study of Zanzalintinib vs Everolimus in Participants With Previously Treated, Unresectable, Locally Advanced or Metastatic Neuroendocrine Tumors",
"has_exemption": false,
"start_date": "2025-07-21",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Exelixis",
"sponsor_slug": "exelixis",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06960759",
"publication_url": "https://clinicaltrials.gov/study/NCT06960759",
"title": "Mechanisms of Change in Behavioral Cough Suppression Therapy for Refractory Chronic Cough",
"has_exemption": false,
"start_date": "2025-08-01",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Montana",
"sponsor_slug": "university-of-montana",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07217860",
"publication_url": "https://clinicaltrials.gov/study/NCT07217860",
"title": "A Multicenter, Long-term, Open-Label, Safety, Tolerability, and Efficacy Study of Azetukalner in Bipolar I or II Depression",
"has_exemption": false,
"start_date": "2025-10-30",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Xenon Pharmaceuticals Inc.",
"sponsor_slug": "xenon-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07174310",
"publication_url": "https://clinicaltrials.gov/study/NCT07174310",
"title": "A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early-Stage Parkinson's Disease",
"has_exemption": false,
"start_date": "2025-11-24",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07211958",
"publication_url": "https://clinicaltrials.gov/study/NCT07211958",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Revumenib in Combination With Intensive Chemotherapy in Participants With Newly Diagnosed AML With an NPM1 Mutation",
"has_exemption": false,
"start_date": "2025-11-25",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Syndax Pharmaceuticals",
"sponsor_slug": "syndax-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06291064",
"publication_url": "https://clinicaltrials.gov/study/NCT06291064",
"title": "TreAtment Response and Omic-Markers in Triple-Negative Breast CAncer Patients Receiving Standard of Care Chemotherapy (TARMAC)",
"has_exemption": false,
"start_date": "2025-11-30",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07287995",
"publication_url": "https://clinicaltrials.gov/study/NCT07287995",
"title": "A Phase 1b/2 Study of ASP2998 as Monotherapy and in Combination With Standard Therapies in Participants With Locally Advanced Unresectable or Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2025-12-15",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Astellas Pharma Global Development, Inc.",
"sponsor_slug": "astellas-pharma-global-development-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07339111",
"publication_url": "https://clinicaltrials.gov/study/NCT07339111",
"title": "Randomized, Prospective, Double Blind, Multi-Center, Phase 3 Pivotal Clinical Trial to Compare Efficacy and Safety of CARTISTEM® and Surgical Comparator in Subjects With Knee Cartilage Lesions and Osteoarthritis",
"has_exemption": false,
"start_date": "2025-12-15",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Medipost, Inc.",
"sponsor_slug": "medipost-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07116395",
"publication_url": "https://clinicaltrials.gov/study/NCT07116395",
"title": "Outcomes of Tranexamic Acid With Anticoagulants in Orthopaedic Trauma Procedures: A Prospective Study",
"has_exemption": false,
"start_date": "2026-01-01",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Arbi Nazarian, MD",
"sponsor_slug": "arbi-nazarian-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06811545",
"publication_url": "https://clinicaltrials.gov/study/NCT06811545",
"title": "Exploring the Effects of Multi-Joint Neuromuscular Electrical Stimulation on Training Gait of Children With Cerebral Palsy",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Nebraska",
"sponsor_slug": "university-of-nebraska",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06907173",
"publication_url": "https://clinicaltrials.gov/study/NCT06907173",
"title": "Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Virginia",
"sponsor_slug": "university-of-virginia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06996652",
"publication_url": "https://clinicaltrials.gov/study/NCT06996652",
"title": "An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD)",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07103746",
"publication_url": "https://clinicaltrials.gov/study/NCT07103746",
"title": "Study of Ublituximab in Early, Active, Autoantibody-Positive, IMMune-MedIated NecroTizing Myopathy (AIM01)",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Allergy and Infectious Diseases (NIAID)",
"sponsor_slug": "national-institute-of-allergy-and-infectious-diseases-niaid",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07298447",
"publication_url": "https://clinicaltrials.gov/study/NCT07298447",
"title": "An Open-Label Study of Donidalorsen in Pediatric Patients Age 2 to Less Than 12 Years Old With Hereditary Angioedema",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Ionis Pharmaceuticals, Inc.",
"sponsor_slug": "ionis-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07325513",
"publication_url": "https://clinicaltrials.gov/study/NCT07325513",
"title": "Machine Learning in Guiding rTMS Treatment for GWI-Related Headaches and Body Pain",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2029-06-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Veterans Medical Research Foundation",
"sponsor_slug": "veterans-medical-research-foundation",
"status": "ongoing",
"is_pact": false,
"days_late": null
}
]
}