HTTP 200 OK
Allow: GET, POST, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"recordsFiltered": 50704,
"recordsTotal": 50704,
"next": "http://fdaaa.trialstracker.net/api/trials/?format=api&length=300&ordering=-sponsor__name&start=49200",
"previous": "http://fdaaa.trialstracker.net/api/trials/?format=api&length=300&ordering=-sponsor__name&start=48600",
"results": [
{
"registry_id": "NCT07511049",
"publication_url": "https://clinicaltrials.gov/study/NCT07511049",
"title": "Safety and Tolerability of Intravenous Brincidofovir as an Antiviral for Treatment of Progressive Multifocal Leukoencephalopathy: A Pilot Study",
"has_exemption": false,
"start_date": "2026-06-05",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Neurological Disorders and Stroke (NINDS)",
"sponsor_slug": "national-institute-of-neurological-disorders-and-stroke-ninds",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07220915",
"publication_url": "https://clinicaltrials.gov/study/NCT07220915",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of Panzyga for Prevention of Major Infection in Patients With Hypogammaglobulinemia and Autoimmune or Rheumatic Conditions Receiving Treatment With B-cell Depletion Therapy (\"PROTECT\")",
"has_exemption": false,
"start_date": "2026-06-10",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Octapharma",
"sponsor_slug": "octapharma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07719595",
"publication_url": "https://clinicaltrials.gov/study/NCT07719595",
"title": "Dual-Site Transcutaneous Auricular Nerve Stimulation (taVNS + taTNS) for Disorders of Consciousness After Traumatic Brain Injury: A Pilot Efficacy Study",
"has_exemption": false,
"start_date": "2026-06-26",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sima Mofakham",
"sponsor_slug": "sima-mofakham",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07285148",
"publication_url": "https://clinicaltrials.gov/study/NCT07285148",
"title": "An Open-label, Multicenter Phase Ib/II Study to Evaluate the Safety, Efficacy and Pharmacokinetic Characteristics of ANS014004 in Combination With EGFR-TKI in Patients With EGFR Mutation-Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Beijing Pearl Biotechnology Limited Liability Company",
"sponsor_slug": "beijing-pearl-biotechnology-limited-liability-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07689149",
"publication_url": "https://clinicaltrials.gov/study/NCT07689149",
"title": "Safety and Efficacy of BiTE in Desensitization Therapy for Highly Sensitized Kidney Transplant Candidates With cPRA ≥ 90%",
"has_exemption": false,
"start_date": "2026-06-30",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "West China Hospital",
"sponsor_slug": "west-china-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07454980",
"publication_url": "https://clinicaltrials.gov/study/NCT07454980",
"title": "Pivotal TRIal to Evaluate TraNsvenous TrIcuspid Valve ReplacemenT With Lux Valve Plus System in Patients With Severe or Greater Tricuspid Regurgitation - Clinical SafetY and Effectiveness",
"has_exemption": false,
"start_date": "2026-07-15",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Jenscare Innovation Inc.",
"sponsor_slug": "jenscare-innovation-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07689578",
"publication_url": "https://clinicaltrials.gov/study/NCT07689578",
"title": "Safety and Efficacy of the Bispecific T-Cell Engager (BiTE) in Kidney Transplant Recipients With Chronic Active Antibody-Mediated Rejection",
"has_exemption": false,
"start_date": "2026-07-30",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Turun Song",
"sponsor_slug": "turun-song",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07762170",
"publication_url": "https://clinicaltrials.gov/study/NCT07762170",
"title": "Success Rates and Safety in Managing Spinal and Sacro-Iliac Pain: A Critical Analysis",
"has_exemption": false,
"start_date": "2026-07-30",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Igor Wilderman. MD",
"sponsor_slug": "igor-wilderman-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07214376",
"publication_url": "https://clinicaltrials.gov/study/NCT07214376",
"title": "A Randomized Placebo-procedure Controlled Trial of the Multi-Pole Pulmonary Artery Radiofrequency Ablation Enhancor System PULmonary Artery Denervation Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease",
"has_exemption": false,
"start_date": "2026-08-21",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Pulnovo Medical, Inc.",
"sponsor_slug": "pulnovo-medical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07564141",
"publication_url": "https://clinicaltrials.gov/study/NCT07564141",
"title": "A Randomized, Open-label, Phase 3 Study of Rina-S ± Bevacizumab Versus Investigator's Choice of Platinum-Based Chemotherapy ± Bevacizumab as 2L Treatment in Participants With Recurrent Platinum-Sensitive Ovarian Cancer",
"has_exemption": false,
"start_date": "2026-08-28",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Genmab",
"sponsor_slug": "genmab",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07686107",
"publication_url": "https://clinicaltrials.gov/study/NCT07686107",
"title": "T2023-004 Phase 2 Trial of Revumenib (SNDX-5613) in Combination With FLA Chemotherapy for Children With Relapsed or Refractory NUP98-rearranged Acute Myeloid Leukemia",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Therapeutic Advances in Childhood Leukemia Consortium",
"sponsor_slug": "therapeutic-advances-in-childhood-leukemia-consortium",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07770633",
"publication_url": "https://clinicaltrials.gov/study/NCT07770633",
"title": "Randomized Controlled Clinical Trial for Closed Incision Negative Pressure Wound Therapy (NPWT) Devices in Total Knee Arthroplasty (TKA)",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Cleveland Clinic",
"sponsor_slug": "the-cleveland-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07835321",
"publication_url": "https://clinicaltrials.gov/study/NCT07835321",
"title": "Characterising the Pharmacokinetics of Tafenoquine Under Fed Conditions for Plasmodium Vivax Radical Cure in Children ≤12kg and >28 Days Old",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Oxford",
"sponsor_slug": "university-of-oxford",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06820138",
"publication_url": "https://clinicaltrials.gov/study/NCT06820138",
"title": "Low Intensity Focused Ultrasound for Posttraumatic Stress Disorder",
"has_exemption": false,
"start_date": "2026-09-09",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07756645",
"publication_url": "https://clinicaltrials.gov/study/NCT07756645",
"title": "A Randomized, Multiregional, Open-Label Phase 3 Clinical Trial of ABBV-1480 Combined With Chemotherapy Versus Pembrolizumab Combined With Chemotherapy for the First Line Treatment of Locally Advanced/Metastatic Non-Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2026-09-22",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07817875",
"publication_url": "https://clinicaltrials.gov/study/NCT07817875",
"title": "Efficacy, Safety, and Pharmacokinetics of Tirzepatide Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial",
"has_exemption": false,
"start_date": "2026-09-25",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07109817",
"publication_url": "https://clinicaltrials.gov/study/NCT07109817",
"title": "Desloratadine to Prevent Taxane-induced Peripheral Neuropathy in Patients With Breast Cancer (DETOXp)",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Montefiore Medical Center",
"sponsor_slug": "montefiore-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07600658",
"publication_url": "https://clinicaltrials.gov/study/NCT07600658",
"title": "A Phase I/II, First-In-Human Trial to Evaluate the Safety, Tolerability, and Pharmacokinetic Activity to Prevent or Treat Neuropsychiatric Symptoms in Pediatric Subjects With Timothy Syndrome",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07699380",
"publication_url": "https://clinicaltrials.gov/study/NCT07699380",
"title": "METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Washington",
"sponsor_slug": "university-of-washington",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07746271",
"publication_url": "https://clinicaltrials.gov/study/NCT07746271",
"title": "Gestational Hypertension and Preeclampsia Blood Pressure (BP) Treatment Goals Less Than 140/90 vs. Less Than 160/110 mmHg: The GOALPOST Trial",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The George Washington University Biostatistics Center",
"sponsor_slug": "the-george-washington-university-biostatistics-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07764874",
"publication_url": "https://clinicaltrials.gov/study/NCT07764874",
"title": "An MR Guided Focused Ultrasound (MRgFUS) Randomized Trial Using the Exablate Neuro System to Assess the Effectiveness and Safety Outcomes of Unilateral and Staged Bilateral Ablation in the Subthalamic Region Involving the Pallidothalamic Tract (PTT) in Advanced Parkinson's Disease (PD) With Motor Complications.",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "InSightec",
"sponsor_slug": "insightec",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07825454",
"publication_url": "https://clinicaltrials.gov/study/NCT07825454",
"title": "A Phase II Single-Arm Pilot Study of Hydroxychloroquine for the Treatment of Aromatase Inhibitor-Associated Musculoskeletal Syndrome",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07300982",
"publication_url": "https://clinicaltrials.gov/study/NCT07300982",
"title": "Studies of Insulin and Glucagon Action in the Liver",
"has_exemption": false,
"start_date": "2026-10-31",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Duke University",
"sponsor_slug": "duke-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07308938",
"publication_url": "https://clinicaltrials.gov/study/NCT07308938",
"title": "Trial of Topical Fluorometholone as Adjunctive Therapy for Bacterial Corneal Ulcers",
"has_exemption": false,
"start_date": "2026-10-31",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Vishal Jhanji",
"sponsor_slug": "vishal-jhanji",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07752095",
"publication_url": "https://clinicaltrials.gov/study/NCT07752095",
"title": "Deep Brain Stimulation of the Deep Cerebellar Nuclei in Subjects With Spinocerebellar Ataxia: A Safety and Feasibility Study",
"has_exemption": false,
"start_date": "2026-10-31",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Gordon H. Baltuch",
"sponsor_slug": "gordon-h-baltuch",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07027969",
"publication_url": "https://clinicaltrials.gov/study/NCT07027969",
"title": "Efficacy of Cardiometabolic Risk Factor Control Through Metabolic Surgery on Management and Severity of Atrial Fibrillation: METSAFE Randomized Clinical Trial",
"has_exemption": false,
"start_date": "2026-11-01",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ali Aminian",
"sponsor_slug": "ali-aminian",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07594145",
"publication_url": "https://clinicaltrials.gov/study/NCT07594145",
"title": "Accelerating Breakthrough Targeted New Therapies for Cardio-Renal Complications in People With T1D (Precision T1D Platform)",
"has_exemption": false,
"start_date": "2026-11-01",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Oregon Health and Science University",
"sponsor_slug": "oregon-health-and-science-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07714876",
"publication_url": "https://clinicaltrials.gov/study/NCT07714876",
"title": "A Prospective, Multicenter Clinical Study to Evaluate the Safety and Effectiveness of the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal Atrial Fibrillation - Post Approval Study",
"has_exemption": false,
"start_date": "2026-12-31",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Kardium Inc.",
"sponsor_slug": "kardium-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07767110",
"publication_url": "https://clinicaltrials.gov/study/NCT07767110",
"title": "Phase 1/2a Study to Determine the Safety of Intratumoral Infusion of Large Surface Area Microparticle (LSAM)-Cisplatin in Participants With Diffuse Midline Glioma (DMG), Including Diffuse Intrinsic Pontine Glioma (DIPG)",
"has_exemption": false,
"start_date": "2026-12-31",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "NanOlogy, LLC",
"sponsor_slug": "nanology-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07772245",
"publication_url": "https://clinicaltrials.gov/study/NCT07772245",
"title": "Phase II Trial of Retifanlimab With Trastuzumab and Pertuzumab Combination in HER2-Addicted Breast Cancer",
"has_exemption": false,
"start_date": "2026-12-31",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Polly A. Niravath, MD",
"sponsor_slug": "polly-a-niravath-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07816159",
"publication_url": "https://clinicaltrials.gov/study/NCT07816159",
"title": "Middle Meningeal Artery Infusion of Lidocaine for Treatment of Headache in Patients With Aneurysmal Subarachnoid Hemorrhage",
"has_exemption": false,
"start_date": "2026-12-31",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Copenhagen University Hospital, Rigshospitalet",
"sponsor_slug": "copenhagen-university-hospital-rigshospitalet",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07792915",
"publication_url": "https://clinicaltrials.gov/study/NCT07792915",
"title": "A Clinical Trial of Resistant Potato Starch for Gut MDRO Decolonization",
"has_exemption": false,
"start_date": "2027-01-01",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07815613",
"publication_url": "https://clinicaltrials.gov/study/NCT07815613",
"title": "Characterizing Absorption Kinetics of Oral Antibiotics in Young Infants to Enhance Precision Dosing",
"has_exemption": false,
"start_date": "2027-01-01",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07464145",
"publication_url": "https://clinicaltrials.gov/study/NCT07464145",
"title": "A Phase 3 Study Evaluating the Efficacy and Safety of NDV-01 in Participants With Non-muscle Invasive Bladder Cancer (RESCUE)",
"has_exemption": false,
"start_date": "2027-02-28",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Relmada Therapeutics, Inc.",
"sponsor_slug": "relmada-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07850973",
"publication_url": "https://clinicaltrials.gov/study/NCT07850973",
"title": "Phase 1/2 Study Of PARP Inhibition With Olaparib To Enhance The Efficacy Of High-Dose Chemotherapy In Refractory And Relapsed Germ Cell Tumors",
"has_exemption": false,
"start_date": "2027-03-01",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05249556",
"publication_url": "https://clinicaltrials.gov/study/NCT05249556",
"title": "Double-blind, Randomized, Placebo-controlled Trial of Adjunctive Ganaxolone in the Treatment of Seizures Associated With Genetically Confirmed Cyclin-dependent Kinase-like 5 (CDKL5) Deficiency Disorder (CDD) in Pediatric Patients From 6 Months to Less Than 2 Years of Age.",
"has_exemption": false,
"start_date": "2027-03-31",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Immedica Pharma AB",
"sponsor_slug": "immedica-pharma-ab",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04381130",
"publication_url": "https://clinicaltrials.gov/study/NCT04381130",
"title": "A Phase I/IIa Study to Determine the Maximum Tolerated Dose (MTD) and to Evaluate the Safety and Efficacy Profile of EF-009 in Patients With Pancreatic Cancer",
"has_exemption": false,
"start_date": "2027-04-01",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Everfront Biotech Co., Ltd.",
"sponsor_slug": "everfront-biotech-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07808333",
"publication_url": "https://clinicaltrials.gov/study/NCT07808333",
"title": "NADIR Trial: A Principal Investigator-Initiated, Single-Center, Open-Label, Active-Controlled Phase 2a Study of High-Dose Nicotinamide (Vitamin B3) Supplementation in Adults With Mild to Moderate Primary Open-Angle Glaucoma (POAG)",
"has_exemption": false,
"start_date": "2027-06-01",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02864888",
"publication_url": "https://clinicaltrials.gov/study/NCT02864888",
"title": "A Controlled, Study of the Effect of Combination Antineoplaston Therapy [Atengenal (A10) and Astugenal (AS2-1)] on the QT/QTc Interval In Subjects With Newly Diagnosed Diffuse, Intrinsic, Brainstem Glioma",
"has_exemption": false,
"start_date": "2027-06-30",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Burzynski Research Institute",
"sponsor_slug": "burzynski-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05526898",
"publication_url": "https://clinicaltrials.gov/study/NCT05526898",
"title": "Multi-Center, Randomized Controlled Trial Evaluating the Effect of Adipose Tissue Processed With the SyntrFuge™ System for Knee Osteoarthritis",
"has_exemption": false,
"start_date": "2027-12-01",
"completion_date": "2029-12-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Syntr Health Technologies, Inc.",
"sponsor_slug": "syntr-health-technologies-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03206060",
"publication_url": "https://clinicaltrials.gov/study/NCT03206060",
"title": "Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma",
"has_exemption": false,
"start_date": "2017-10-10",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03952637",
"publication_url": "https://clinicaltrials.gov/study/NCT03952637",
"title": "A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis",
"has_exemption": false,
"start_date": "2019-08-19",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Human Genome Research Institute (NHGRI)",
"sponsor_slug": "national-human-genome-research-institute-nhgri",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04337515",
"publication_url": "https://clinicaltrials.gov/study/NCT04337515",
"title": "A Feasibility Study of Using the CiniMacs® Device for Alpha/Best T-Cell Depletion in Stem Cell Transplant Recipients",
"has_exemption": false,
"start_date": "2019-12-19",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Christopher Dvorak",
"sponsor_slug": "christopher-dvorak",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05088798",
"publication_url": "https://clinicaltrials.gov/study/NCT05088798",
"title": "Use of18F-DOPA PET/MRI for the Detection and Localization of Focal Forms of Hyperinsulinism",
"has_exemption": false,
"start_date": "2020-09-10",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06089707",
"publication_url": "https://clinicaltrials.gov/study/NCT06089707",
"title": "Behavioral Pharmacological Examination of a Novel Buprenorphine Induction Method Among Individuals Who Use Fentanyl",
"has_exemption": false,
"start_date": "2024-01-09",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Maryland, Baltimore",
"sponsor_slug": "university-of-maryland-baltimore",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02773082",
"publication_url": "https://clinicaltrials.gov/study/NCT02773082",
"title": "Reclaim™ Deep Brain Stimulation (DBS) Therapy for Obsessive-Compulsive Disorder (OCD)",
"has_exemption": false,
"start_date": "2024-07-06",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwell Health",
"sponsor_slug": "northwell-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06068543",
"publication_url": "https://clinicaltrials.gov/study/NCT06068543",
"title": "A Phase 2 Randomized Controlled Trial of Epigallocatechin-3-Gallate (EGCG) on Frailty and Inflammation in Older Survivors of Cancer",
"has_exemption": false,
"start_date": "2024-10-25",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Rochester",
"sponsor_slug": "university-of-rochester",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07043972",
"publication_url": "https://clinicaltrials.gov/study/NCT07043972",
"title": "Phase II Study of Second-line Gemcitabine Plus Carboplatin After Progression on Enfortumab Vedotin With Pembrolizumab in Advanced or Metastatic Urothelial Carcinoma",
"has_exemption": false,
"start_date": "2025-07-09",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Fox Chase Cancer Center",
"sponsor_slug": "fox-chase-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06440707",
"publication_url": "https://clinicaltrials.gov/study/NCT06440707",
"title": "Transcranial Electrical Stimulation in Stroke EaRly After Onset Clinical Trial 2",
"has_exemption": false,
"start_date": "2025-07-15",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, Los Angeles",
"sponsor_slug": "university-of-california-los-angeles",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07300865",
"publication_url": "https://clinicaltrials.gov/study/NCT07300865",
"title": "Does the Thickness of the Gastrostomy Affect the Incidence of Complications? A Prospective Randomized Single-Center Study in Children",
"has_exemption": false,
"start_date": "2025-11-20",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Therese Hössjer",
"sponsor_slug": "therese-hossjer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07506239",
"publication_url": "https://clinicaltrials.gov/study/NCT07506239",
"title": "PNOC042: A Phase 2, Multi-institutional Trial, Evaluating the Efficacy of Laser Interstitial Thermal Therapy (LITT) in Children, Adolescents and Young Adults With Recurrent or Progressive Low-grade Gliomas (LGG)",
"has_exemption": false,
"start_date": "2026-03-25",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of California, San Francisco",
"sponsor_slug": "university-of-california-san-francisco",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07220252",
"publication_url": "https://clinicaltrials.gov/study/NCT07220252",
"title": "Ublituximab in Pediatric Participants With Relapsing Forms of Multiple Sclerosis (RMS)",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "TG Therapeutics, Inc.",
"sponsor_slug": "tg-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06303193",
"publication_url": "https://clinicaltrials.gov/study/NCT06303193",
"title": "Phase I/II Trial of Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms",
"has_exemption": false,
"start_date": "2026-10-25",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06214793",
"publication_url": "https://clinicaltrials.gov/study/NCT06214793",
"title": "A Phase II Study of Taletrectinib in Previously Treated Metastatic CDH1-mutated Invasive Lobular Cancer (ILC) of the Breast (TaCe)",
"has_exemption": false,
"start_date": "2026-10-31",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Megan Kruse, MD",
"sponsor_slug": "megan-kruse-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07502872",
"publication_url": "https://clinicaltrials.gov/study/NCT07502872",
"title": "TPG: a Phase 2 Trial of Polatuzumab Vedotin, Glofitamab, and Tafasitamab as Chemotherapy-sparing First-line Therapy for Diffuse Large B-cell Lymphoma and High-grade B-cell Lymphoma",
"has_exemption": false,
"start_date": "2026-11-01",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Brown University",
"sponsor_slug": "brown-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07647614",
"publication_url": "https://clinicaltrials.gov/study/NCT07647614",
"title": "A Phase II, Randomized, Double-blind, Placebo-controlled, Parallel Study to Evaluate the Efficacy and Safety of ENERGI-F705 Tablets in Combination With Standard of Care for Treating Subjects With Parkinson's Disease",
"has_exemption": false,
"start_date": "2026-12-01",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Energenesis Biomedical Co., Ltd.",
"sponsor_slug": "energenesis-biomedical-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07587879",
"publication_url": "https://clinicaltrials.gov/study/NCT07587879",
"title": "A Phase 1/2a Clinical Study to Evaluate the Safety Tolerability, Pharmacokinetics, and Preliminary Efficacy of a Novel mRNA-LNP PMC2129G12-Based Immunotherapy in Patients With Advanced Malignant Solid Tumors",
"has_exemption": false,
"start_date": "2027-01-01",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "IntraAb, Inc.",
"sponsor_slug": "intraab-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07635862",
"publication_url": "https://clinicaltrials.gov/study/NCT07635862",
"title": "A Randomized Controlled Trial of Ganaxolone for Children With Autism Spectrum Disorder",
"has_exemption": false,
"start_date": "2027-01-01",
"completion_date": "2030-01-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07857122",
"publication_url": "https://clinicaltrials.gov/study/NCT07857122",
"title": "Evaluating the Therapeutic Potential of Focal Electrically Administered Seizure Therapy (FEAST) in the Treatment of Depression: A Multicenter Randomized Clinical Trial",
"has_exemption": false,
"start_date": "2026-11-02",
"completion_date": "2030-01-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Centre Hospitalier St Anne",
"sponsor_slug": "centre-hospitalier-st-anne",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07213674",
"publication_url": "https://clinicaltrials.gov/study/NCT07213674",
"title": "A Phase 3, Open-label, Multicenter, Randomized Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer",
"has_exemption": false,
"start_date": "2025-11-28",
"completion_date": "2030-01-07",
"has_results": false,
"results_due": false,
"sponsor_name": "Amgen",
"sponsor_slug": "amgen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07839585",
"publication_url": "https://clinicaltrials.gov/study/NCT07839585",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Sotatercept in Adults With Combined Postcapillary and Precapillary Pulmonary Hypertension (CpcPH) and Heart Failure With Preserved Ejection Fraction (HFpEF)",
"has_exemption": false,
"start_date": "2026-11-26",
"completion_date": "2030-01-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07335796",
"publication_url": "https://clinicaltrials.gov/study/NCT07335796",
"title": "A Phase 2 Study of Androgen Deprivation Therapy and BMS986365 in High-Risk Localized Prostate Cancer Patients Prior to Radical Prostatectomy",
"has_exemption": false,
"start_date": "2026-01-09",
"completion_date": "2030-01-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07517263",
"publication_url": "https://clinicaltrials.gov/study/NCT07517263",
"title": "A Single Arm, Multicenter, Open-label Extension (OLE) Trial to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) in Participants Who Completed the Parent Lp(a)HORIZON Trial",
"has_exemption": false,
"start_date": "2026-05-11",
"completion_date": "2030-01-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06399861",
"publication_url": "https://clinicaltrials.gov/study/NCT06399861",
"title": "Humidity in Incubators for Tiny Infants (HumidITI) Trial",
"has_exemption": false,
"start_date": "2024-06-25",
"completion_date": "2030-01-15",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07459751",
"publication_url": "https://clinicaltrials.gov/study/NCT07459751",
"title": "A Randomized, Open-Label, Multi-center, Global Phase II/III Clinical Study to Evaluate the Efficacy and Safety of HLX43 (Anti-PD-L1 ADC) Monotherapy or HLX43 in Combination With HLX07 (Recombinant Anti-EGFR Humanized Monoclonal Antibody Injection) Versus Docetaxel in Previously Treated Advanced or Metastatic Squamous Non-Small Cell Lung Cancer (NSCLC)",
"has_exemption": false,
"start_date": "2026-05-27",
"completion_date": "2030-01-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Shanghai Henlius Biotech",
"sponsor_slug": "shanghai-henlius-biotech",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05800015",
"publication_url": "https://clinicaltrials.gov/study/NCT05800015",
"title": "A Randomized, Double-Blind Phase 2/3 Study of Fianlimab (Anti-LAG-3 Antibody), Cemiplimab (Anti-PD-1 Antibody), and Chemotherapy Versus Cemiplimab and Chemotherapy in First-Line Treatment of Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) Irrespective of PD-L1 Expression Levels",
"has_exemption": false,
"start_date": "2023-08-08",
"completion_date": "2030-01-16",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT01687608",
"publication_url": "https://clinicaltrials.gov/study/NCT01687608",
"title": "A Phase 1/2 Open-Label, Single Ascending Dose Trial of a Self-Complementing Optimized Adeno-associated Virus Serotype 8 Factor IX Gene Therapy (AskBio009) in Adults With Hemophilia B",
"has_exemption": false,
"start_date": "2013-02-11",
"completion_date": "2030-01-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Baxalta now part of Shire",
"sponsor_slug": "baxalta-now-part-of-shire",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT06868277",
"publication_url": "https://clinicaltrials.gov/study/NCT06868277",
"title": "A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab Monotherapy for the First-line Treatment of Patients With PD-L1-high Metastatic Non-small Cell Lung Cancer (ARTEMIDE-Lung04)",
"has_exemption": false,
"start_date": "2025-04-10",
"completion_date": "2030-01-17",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06572605",
"publication_url": "https://clinicaltrials.gov/study/NCT06572605",
"title": "A Phase 1b/2 Study of Talquetamab Plus Concomitant Priming Radiotherapy in Multiple Myeloma With Extramedullary Disease",
"has_exemption": false,
"start_date": "2025-08-29",
"completion_date": "2030-01-18",
"has_results": false,
"results_due": false,
"sponsor_name": "City of Hope Medical Center",
"sponsor_slug": "city-of-hope-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07154745",
"publication_url": "https://clinicaltrials.gov/study/NCT07154745",
"title": "A Single Arm Study to Evaluate the Efficacy and Safety of Pozelimab and Cemdisiran Combination Therapy in Patients With Paroxysmal Nocturnal Hemoglobinuria With Inadequate Control of Intravascular Hemolysis on Currently Available C5 Inhibitor Therapy",
"has_exemption": false,
"start_date": "2026-06-11",
"completion_date": "2030-01-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07410117",
"publication_url": "https://clinicaltrials.gov/study/NCT07410117",
"title": "A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess Efficacy and Safety of REGN7508, a Monoclonal Antibody Against FXI, for Primary Prophylaxis of Cancer-Associated Thrombosis for Participants With Solid Tumors Undergoing Cancer Treatment (ROXI-CAT-I)",
"has_exemption": false,
"start_date": "2026-03-09",
"completion_date": "2030-01-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06962800",
"publication_url": "https://clinicaltrials.gov/study/NCT06962800",
"title": "An Open-Label, Multicenter, Randomized Phase 3 Study Evaluating the Efficacy and Safety of Felzartamab in Participants With Primary Membranous Nephropathy (PMN) [PROMINENT]",
"has_exemption": false,
"start_date": "2025-05-22",
"completion_date": "2030-01-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Biogen",
"sponsor_slug": "biogen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04638647",
"publication_url": "https://clinicaltrials.gov/study/NCT04638647",
"title": "An Open-label, Multi-center Protocol for Patients Who Have Completed a Previous Novartis Sponsored Secukinumab Study and Are Judged by the Investigator to Benefit From Continued Secukinumab Treatment",
"has_exemption": false,
"start_date": "2020-12-22",
"completion_date": "2030-01-29",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04008368",
"publication_url": "https://clinicaltrials.gov/study/NCT04008368",
"title": "Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease or Beta-Thalassemia and Falling Donor Myeloid Chimerism Levels",
"has_exemption": false,
"start_date": "2019-10-24",
"completion_date": "2030-01-30",
"has_results": false,
"results_due": false,
"sponsor_name": "National Heart, Lung, and Blood Institute (NHLBI)",
"sponsor_slug": "national-heart-lung-and-blood-institute-nhlbi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05285553",
"publication_url": "https://clinicaltrials.gov/study/NCT05285553",
"title": "MiSight 1 Day Post-Approval Study for Effectiveness and Visual Symptoms",
"has_exemption": false,
"start_date": "2022-06-25",
"completion_date": "2030-01-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Coopervision, Inc.",
"sponsor_slug": "coopervision-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05464719",
"publication_url": "https://clinicaltrials.gov/study/NCT05464719",
"title": "A Phase II Study of Loncastuximab Tesirine as Consolidation Strategy in Patients With LBCL in PR After CAR T-cell Therapy",
"has_exemption": false,
"start_date": "2022-09-23",
"completion_date": "2030-01-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06205485",
"publication_url": "https://clinicaltrials.gov/study/NCT06205485",
"title": "A Phase 3 Randomized Trial Of Neoadjuvant Chemotherapy, Excision And Observation Versus Chemoradiotherapy For Early Rectal Cancer",
"has_exemption": false,
"start_date": "2024-06-26",
"completion_date": "2030-01-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Canadian Cancer Trials Group",
"sponsor_slug": "canadian-cancer-trials-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07399977",
"publication_url": "https://clinicaltrials.gov/study/NCT07399977",
"title": "A Nonrandomized Trial Using DNA Liquid Biopsies to Guide Anticoagulation For Patients With Cancer-Associated Thromboembolism",
"has_exemption": false,
"start_date": "2026-01-30",
"completion_date": "2030-01-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT00785525",
"publication_url": "https://clinicaltrials.gov/study/NCT00785525",
"title": "Filgrastim-Mobilized Peripheral Blood Stem Cells for Allogeneic Transplantation With Unrelated Donors",
"has_exemption": false,
"start_date": "1997-02-28",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Center for International Blood and Marrow Transplant Research",
"sponsor_slug": "center-for-international-blood-and-marrow-transplant-research",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02605785",
"publication_url": "https://clinicaltrials.gov/study/NCT02605785",
"title": "A Molecular Anatomic Imaging Analysis of Tau in Progressive Supranuclear Palsy",
"has_exemption": false,
"start_date": "2015-11-30",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03599752",
"publication_url": "https://clinicaltrials.gov/study/NCT03599752",
"title": "The Role of Multimodality Management in Risk-Stratified Patients With Lung-Limited Metastatic Colorectal Cancer",
"has_exemption": false,
"start_date": "2018-07-02",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03801083",
"publication_url": "https://clinicaltrials.gov/study/NCT03801083",
"title": "A Phase 2 Study to Evaluate the Efficacy and Safety of Adoptive Transfer of Autologous Tumor Infiltrating Lymphocytes in Patients With Locally Advanced, Recurrent, or Metastatic Biliary Tract Cancers",
"has_exemption": false,
"start_date": "2019-02-19",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Udai Kammula",
"sponsor_slug": "udai-kammula",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03811015",
"publication_url": "https://clinicaltrials.gov/study/NCT03811015",
"title": "A Phase III Randomized Study of Maintenance Nivolumab Versus Observation in Patients With Locally Advanced, Intermediate Risk HPV Positive OPSCC",
"has_exemption": false,
"start_date": "2019-08-16",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04375722",
"publication_url": "https://clinicaltrials.gov/study/NCT04375722",
"title": "Exogenous Tuning of Neural Oscillations as a Mode of Treatment in Post-stroke Aphasia",
"has_exemption": false,
"start_date": "2020-01-04",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04267848",
"publication_url": "https://clinicaltrials.gov/study/NCT04267848",
"title": "Integration of Immunotherapy Into Adjuvant Therapy for Resected NSCLC: ALCHEMIST Chemo-IO (ACCIO)",
"has_exemption": false,
"start_date": "2020-06-16",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04643366",
"publication_url": "https://clinicaltrials.gov/study/NCT04643366",
"title": "Phase 2 Study of Total Neoadjuvant mFOLFOX and Short-Course Radiotherapy in Resectable Rectal Cancer",
"has_exemption": false,
"start_date": "2021-01-28",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Virginia Commonwealth University",
"sponsor_slug": "virginia-commonwealth-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05030441",
"publication_url": "https://clinicaltrials.gov/study/NCT05030441",
"title": "A Pilot Study of Ivosidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH1",
"has_exemption": false,
"start_date": "2022-04-01",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05554302",
"publication_url": "https://clinicaltrials.gov/study/NCT05554302",
"title": "Characterization of 18F-Fluciclovine PET Amino Acid Radiotracer in Resected Brain Metastasis",
"has_exemption": false,
"start_date": "2023-01-10",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Baptist Health South Florida",
"sponsor_slug": "baptist-health-south-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05643742",
"publication_url": "https://clinicaltrials.gov/study/NCT05643742",
"title": "A Phase 1/2, Open-Label, Multicenter, Dose Escalation and Cohort Expansion Study of the Safety and Efficacy of Anti-CD19 Allogeneic CRISPR-Cas9-Engineered T Cells (CTX112) in Subjects With Relapsed or Refractory B Cell Malignancies",
"has_exemption": false,
"start_date": "2023-03-10",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "CRISPR Therapeutics AG",
"sponsor_slug": "crispr-therapeutics-ag",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06193551",
"publication_url": "https://clinicaltrials.gov/study/NCT06193551",
"title": "Ovitex in Paraesophageal and Large Hiatal Hernia Repair. (OviPHeR)",
"has_exemption": false,
"start_date": "2024-02-19",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Foregut Research Foundation",
"sponsor_slug": "foregut-research-foundation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06412666",
"publication_url": "https://clinicaltrials.gov/study/NCT06412666",
"title": "A Phase 2/3 Multicenter, Randomized, Double-Blind, Placebo-Controlled and Open-Label Extension Trial to Evaluate the Efficacy and Safety of Aficamten in a Pediatric Population With Symptomatic Obstructive Hypertrophic Cardiomyopathy",
"has_exemption": false,
"start_date": "2024-05-29",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Cytokinetics",
"sponsor_slug": "cytokinetics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06548542",
"publication_url": "https://clinicaltrials.gov/study/NCT06548542",
"title": "A Phase 2a Multicenter, Randomized, Platform Study of Targeted Therapies for the Treatment of Adult Subjects With Moderate to Severe Crohn's Disease",
"has_exemption": false,
"start_date": "2024-09-04",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06559176",
"publication_url": "https://clinicaltrials.gov/study/NCT06559176",
"title": "A Phase 1/2 Study Evaluating Gene Therapy by Transplantation of Autologous CD34+ Stem Cells Modified Ex Vivo Using Prime Editing (PM359) in Participants With Autosomal Recessive Chronic Granulomatous Disease Due to Mutations in the NCF1 Gene",
"has_exemption": false,
"start_date": "2024-10-17",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Prime Medicine, Inc.",
"sponsor_slug": "prime-medicine-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06857773",
"publication_url": "https://clinicaltrials.gov/study/NCT06857773",
"title": "Hepatic Arterial Infusion PUMP Chemotherapy Combined With Systemic Therapy Versus Systemic Therapy Alone as Induction Therapy for Initially Unresectable Colorectal Liver Metastases: a Randomised Controlled Trial",
"has_exemption": false,
"start_date": "2024-11-21",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The Netherlands Cancer Institute",
"sponsor_slug": "the-netherlands-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06581406",
"publication_url": "https://clinicaltrials.gov/study/NCT06581406",
"title": "A Randomized, Phase 2/3, Open-Label Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab Versus Ipilimumab in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma",
"has_exemption": false,
"start_date": "2024-12-17",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Replimune Inc.",
"sponsor_slug": "replimune-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06607406",
"publication_url": "https://clinicaltrials.gov/study/NCT06607406",
"title": "A Randomized Trial of Accelerated Postoperative Radiotherapy for Intermediate- and High-risk Patients With HNSCC (Head and Neck Squamous Cell Carcinoma) Initiating Radiotherapy Greater Than 6 Weeks After Surgery (PORTRush)",
"has_exemption": false,
"start_date": "2025-01-21",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Wake Forest University Health Sciences",
"sponsor_slug": "wake-forest-university-health-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06842355",
"publication_url": "https://clinicaltrials.gov/study/NCT06842355",
"title": "A Multicenter, Phase 2, Dose-Escalation/Dose-Expansion Study of TYRA-300 in Children With Achondroplasia With Open Growth Plates: BEACH301",
"has_exemption": false,
"start_date": "2025-03-04",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Tyra Biosciences, Inc",
"sponsor_slug": "tyra-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06745882",
"publication_url": "https://clinicaltrials.gov/study/NCT06745882",
"title": "Prospective Trial to Assess Real-world Outcomes and Predictive Biomarkers of Response to Pembrolizumab With or Without Chemotherapy in Black Patients With NSCLC",
"has_exemption": false,
"start_date": "2025-06-13",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "H. Lee Moffitt Cancer Center and Research Institute",
"sponsor_slug": "h-lee-moffitt-cancer-center-and-research-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07076225",
"publication_url": "https://clinicaltrials.gov/study/NCT07076225",
"title": "A Ultrashort Regimen for Drug-susceptible Pulmonary Tuberculosis in Elderly Patients: A Multicenter Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2025-07-25",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Shenzhen Third People's Hospital",
"sponsor_slug": "shenzhen-third-peoples-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07096193",
"publication_url": "https://clinicaltrials.gov/study/NCT07096193",
"title": "Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta",
"has_exemption": false,
"start_date": "2025-07-31",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Gilead Sciences",
"sponsor_slug": "gilead-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07086131",
"publication_url": "https://clinicaltrials.gov/study/NCT07086131",
"title": "Impact Of Adding Inspiratory Muscle Training To Cardiac Rehabilitation On Exercise Responses In Heart Failure",
"has_exemption": false,
"start_date": "2025-09-04",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07213661",
"publication_url": "https://clinicaltrials.gov/study/NCT07213661",
"title": "Long-term Comparative Effectiveness of 2 Treatments to Arrest Dental Caries in Older Adults",
"has_exemption": false,
"start_date": "2025-10-08",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Case Western Reserve University",
"sponsor_slug": "case-western-reserve-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07157254",
"publication_url": "https://clinicaltrials.gov/study/NCT07157254",
"title": "A Phase 2, Open-label, Basket Study Investigating the Safety and Efficacy of GTX-102 in Adult and Pediatric Subjects With Deletion- or Nondeletion-type Angelman Syndrome",
"has_exemption": false,
"start_date": "2025-10-13",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Ultragenyx Pharmaceutical Inc",
"sponsor_slug": "ultragenyx-pharmaceutical-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06200259",
"publication_url": "https://clinicaltrials.gov/study/NCT06200259",
"title": "Reduction of Gastrointestinal Toxicity in Prostate Cancer by Proton Spot Placement",
"has_exemption": false,
"start_date": "2025-12-15",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Covenant Health Cancer Center",
"sponsor_slug": "covenant-health-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07223307",
"publication_url": "https://clinicaltrials.gov/study/NCT07223307",
"title": "Phase II Trial of REal Time MRI GUided Adaptive Stereotactic Ablative Radiotherapy for Liver Cancers Using a Single Session, Simulation Free Workflow",
"has_exemption": false,
"start_date": "2026-01-23",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07303946",
"publication_url": "https://clinicaltrials.gov/study/NCT07303946",
"title": "Double-Blind, Crossover, Feasibility Study of Deep Brain Stimulation of the Anterior Cingulate Bundle (ACB) and the Ventral Anterior Limb of the Internal Capsule (vALIC) in Patients With Intractable Obsessive Compulsive Disorder (OCD)",
"has_exemption": false,
"start_date": "2026-01-31",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Rhode Island Hospital",
"sponsor_slug": "rhode-island-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07369115",
"publication_url": "https://clinicaltrials.gov/study/NCT07369115",
"title": "Intra-Cellular Therapies, Inc. / \"A Randomized, Double-blind, Placebo-controlled, Single Site Study to Evaluate the Efficacy of Lumateperone for the Treatment of Major Depressive Disorder (MDD) and Early Life Trauma in Adult Patients Aged 21 to 70 Years",
"has_exemption": false,
"start_date": "2026-02-28",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas at Austin",
"sponsor_slug": "university-of-texas-at-austin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07280468",
"publication_url": "https://clinicaltrials.gov/study/NCT07280468",
"title": "Endotype DIrected Treatment for OSA in Down Syndrome",
"has_exemption": false,
"start_date": "2026-03-14",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Arizona",
"sponsor_slug": "university-of-arizona",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07497399",
"publication_url": "https://clinicaltrials.gov/study/NCT07497399",
"title": "Targeting Agonists of Glucagon-like Peptide-1 Receptor for Multiple Sclerosis (TAG-MS): A Phase 2, Randomized, Double-Blind, Parallel-Arm Study",
"has_exemption": false,
"start_date": "2026-04-28",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07332442",
"publication_url": "https://clinicaltrials.gov/study/NCT07332442",
"title": "Continuous Positive Airway Pressure, Arousability and Links to Mechanisms in Obstructive Sleep Apnea",
"has_exemption": false,
"start_date": "2026-05-18",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07328503",
"publication_url": "https://clinicaltrials.gov/study/NCT07328503",
"title": "A Phase II Study to Examine the Impact of CD22 CAR T-cells to Extend the Duration of Remission Following Commercial CD19 CAR T-cells in Children, Adolescents, and Adults With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia",
"has_exemption": false,
"start_date": "2026-06-16",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07419425",
"publication_url": "https://clinicaltrials.gov/study/NCT07419425",
"title": "Comparing Three Multicomponent Interventions to Help Adults Quit Smoking",
"has_exemption": false,
"start_date": "2026-07-06",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07288151",
"publication_url": "https://clinicaltrials.gov/study/NCT07288151",
"title": "MDMA-Assisted Massed Exposure Therapy for PTSD",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07625644",
"publication_url": "https://clinicaltrials.gov/study/NCT07625644",
"title": "A Phase 3 Open-Label, Randomized Controlled Trial of BL-M14D1 and Atezolizumab vs. Standard-of-Care Therapy in Patients With First-Line Extensive-Stage Small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2026-08-04",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "SystImmune Inc.",
"sponsor_slug": "systimmune-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07546812",
"publication_url": "https://clinicaltrials.gov/study/NCT07546812",
"title": "A Phase 2, Open-Label, Multicenter, Randomized Study to Evaluate Denikitug as Monotherapy or in Combination With Nivolumab or Chemotherapy in Participants With HER2-Negative, Unresectable, Recurrent, and/or Metastatic Gastric, Gastroesophageal Junction (GEJ), and Esophageal Adenocarcinomas",
"has_exemption": false,
"start_date": "2026-08-07",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Gilead Sciences",
"sponsor_slug": "gilead-sciences",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07010302",
"publication_url": "https://clinicaltrials.gov/study/NCT07010302",
"title": "A Comparative Clinical Effectiveness Trial of Rituximab Versus Ravulizumab, Inebilizumab, Satralizumab and Eculizumab To Prevent Relapses in Neuromyelitis Optica Spectrum Disorder",
"has_exemption": false,
"start_date": "2026-09-01",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07325214",
"publication_url": "https://clinicaltrials.gov/study/NCT07325214",
"title": "A Randomized, Multicenter, Multiregional, Pivotal Clinical Trial to Evaluate the Safety and Efficacy of IMD10 (Focused Ultrasound) in Combination With the Chemotherapy Regimen Consisting of Irinotecan Hydrochloride, Oxaliplatin, Fluorouracil (5-FU) and Leucovorin Improves Overall Survival Compared With the Chemotherapy Regimen Alone in Patients With Borderline Resectable Pancreatic Cancer or Locally Advanced Pancreatic Cancer",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "IMGT Co., Ltd.",
"sponsor_slug": "imgt-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07682792",
"publication_url": "https://clinicaltrials.gov/study/NCT07682792",
"title": "A Pilot Study of Golidocitinib, a JAK1 Inhibitor, in Patients With Mycosis Fungoides/Sézary Syndrome and T-Cell Large Granular Lymphocytic Leukemia (GEMSTONE)",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07264920",
"publication_url": "https://clinicaltrials.gov/study/NCT07264920",
"title": "Pediatric Electrocutaneous Analgesia for Children Experiencing Neuropathic Pain",
"has_exemption": false,
"start_date": "2026-10-31",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Johns Hopkins University",
"sponsor_slug": "johns-hopkins-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07069699",
"publication_url": "https://clinicaltrials.gov/study/NCT07069699",
"title": "Phase 1b/2 Trial of Pidnarulex in MYC Aberrant Lymphoma",
"has_exemption": false,
"start_date": "2027-01-11",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07470164",
"publication_url": "https://clinicaltrials.gov/study/NCT07470164",
"title": "A Randomized Trial of Botulinum Toxin A vs Strabismus Surgery for Esotropia >10 to ≤30PD",
"has_exemption": false,
"start_date": "2027-01-31",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Jaeb Center for Health Research",
"sponsor_slug": "jaeb-center-for-health-research",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07662278",
"publication_url": "https://clinicaltrials.gov/study/NCT07662278",
"title": "A Randomized, Multi-Center, Open-Label, Phase II Study to Evaluate the Efficacy and Safety of Recombinant Super-Compound Interferon (rSIFN-co) in Combination With Total Neo-adjuvant Therapy, in Subjects With Mid-low Locally Advanced Rectal Cancer",
"has_exemption": false,
"start_date": "2027-01-31",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Sichuan Huiyang Life Science and Technology Corporation",
"sponsor_slug": "sichuan-huiyang-life-science-and-technology-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07592000",
"publication_url": "https://clinicaltrials.gov/study/NCT07592000",
"title": "Multicenter, Phase 1/2 Pilot Study of Safety and Efficacy Assessment of Tegoprubart and Calcineurin Inhibitors- Free Immunosuppression Therapy for Pancreatic Islet Transplantation in Patients With T1DM and Chronic Kidney Disease",
"has_exemption": false,
"start_date": "2027-04-29",
"completion_date": "2030-01-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT01754363",
"publication_url": "https://clinicaltrials.gov/study/NCT01754363",
"title": "Short, Medium and Long Term Survivorship of Attune Primary Knee Prosthesis",
"has_exemption": false,
"start_date": "2013-02-01",
"completion_date": "2030-02-01",
"has_results": false,
"results_due": false,
"sponsor_name": "DePuy International",
"sponsor_slug": "depuy-international",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT06919666",
"publication_url": "https://clinicaltrials.gov/study/NCT06919666",
"title": "Phase Ib/II Study of NT219 in Combination With Pembrolizumab or Cetuximab in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)",
"has_exemption": false,
"start_date": "2025-06-12",
"completion_date": "2030-02-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06853665",
"publication_url": "https://clinicaltrials.gov/study/NCT06853665",
"title": "A Pharmaco-Imaging Trial of Mixed Amphetamine Salts for the Treatment of ADHD in Intellectually-intact Youth With Autism Spectrum Disorder",
"has_exemption": false,
"start_date": "2026-02-01",
"completion_date": "2030-02-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Gagan Joshi",
"sponsor_slug": "gagan-joshi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07061951",
"publication_url": "https://clinicaltrials.gov/study/NCT07061951",
"title": "A Phase 2 Pilot Study of Mirdametinib in Relapsed Refractory Chronic Lymphocytic Leukemia",
"has_exemption": false,
"start_date": "2026-05-27",
"completion_date": "2030-02-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07693608",
"publication_url": "https://clinicaltrials.gov/study/NCT07693608",
"title": "An Open-Label Tirzepatide Trial for Comorbid Obesity and Stimulant Use Disorder Using fMRI to Identify Novel Neural Biomarkers",
"has_exemption": false,
"start_date": "2026-08-19",
"completion_date": "2030-02-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Texas Southwestern Medical Center",
"sponsor_slug": "university-of-texas-southwestern-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07579195",
"publication_url": "https://clinicaltrials.gov/study/NCT07579195",
"title": "Consolidative Radiation Therapy or Cystectomy After Initial Favorable Response Succeeding Enfortumab Vedotin Plus Pembrolizumab (REINFORCE)--- A Pilot Feasibility Trial",
"has_exemption": false,
"start_date": "2026-08-20",
"completion_date": "2030-02-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Washington",
"sponsor_slug": "university-of-washington",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07313787",
"publication_url": "https://clinicaltrials.gov/study/NCT07313787",
"title": "Prospective Cross-Over Study of the Effects of Meal Macronutrients on Postprandial Lipids",
"has_exemption": false,
"start_date": "2026-10-25",
"completion_date": "2030-02-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
"sponsor_slug": "national-institute-of-diabetes-and-digestive-and-kidney-diseases-niddk",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07439510",
"publication_url": "https://clinicaltrials.gov/study/NCT07439510",
"title": "A Phase 2b/3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Codabakalner in Male Participants With Full Mutation Fragile X Syndrome and Adult Participants With Autism Spectrum Disorders",
"has_exemption": false,
"start_date": "2026-12-01",
"completion_date": "2030-02-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Spinogenix",
"sponsor_slug": "spinogenix",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07221357",
"publication_url": "https://clinicaltrials.gov/study/NCT07221357",
"title": "ROSETTA CRC-203: A Blinded, Randomized Phase 2/3 Study of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer",
"has_exemption": false,
"start_date": "2025-12-31",
"completion_date": "2030-02-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06413680",
"publication_url": "https://clinicaltrials.gov/study/NCT06413680",
"title": "A Phase 1/2a, Open-Label, Dose Escalation and Dose Expansion First-In-Human Study of the Safety, Tolerability, Activity, and Pharmacokinetics of REGN10597 (Anti-PD-1-IL-2RA-IL-2 Fusion Protein) Alone or in Combination With Cemiplimab in Patients With Advanced Solid Organ Malignancies",
"has_exemption": false,
"start_date": "2024-09-23",
"completion_date": "2030-02-03",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07748611",
"publication_url": "https://clinicaltrials.gov/study/NCT07748611",
"title": "SMART-PANC: SMAD4 Tailored Neoadjuvant Therapy for Pancreatic Cancer, A Phase ll Non-Randomized, Single Center Pilot Study",
"has_exemption": false,
"start_date": "2027-02-03",
"completion_date": "2030-02-03",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07401823",
"publication_url": "https://clinicaltrials.gov/study/NCT07401823",
"title": "An Open-Label Extension Study to Evaluate Long-Term Safety and Tolerability of Pociredir in Participants With Sickle Cell Disease (SCD) Who Have Participated in a Pociredir Study",
"has_exemption": false,
"start_date": "2026-03-30",
"completion_date": "2030-02-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Fulcrum Therapeutics",
"sponsor_slug": "fulcrum-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03309332",
"publication_url": "https://clinicaltrials.gov/study/NCT03309332",
"title": "OSB Lead-AMPLATZER PFO Occluder New Enrollment PAS",
"has_exemption": false,
"start_date": "2018-01-31",
"completion_date": "2030-02-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Abbott Medical Devices",
"sponsor_slug": "abbott-medical-devices",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT00424866",
"publication_url": "https://clinicaltrials.gov/study/NCT00424866",
"title": "A Phase 1, Open Label, Dose Response, Pilot Study to Evaluate the Safety and Tolerability of Human Fibroblast Growth Factor-1 (FGF-1) in Peripheral Arterial Disease Patients With Intermittent Claudication",
"has_exemption": false,
"start_date": "2028-10-15",
"completion_date": "2030-02-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Venturis Therapeutics, Inc.",
"sponsor_slug": "venturis-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07486921",
"publication_url": "https://clinicaltrials.gov/study/NCT07486921",
"title": "Etrasimod as Primary and Secondary Prevention of Pouchitis (ESPIRIT)",
"has_exemption": false,
"start_date": "2026-07-01",
"completion_date": "2030-02-06",
"has_results": false,
"results_due": false,
"sponsor_name": "Maia Kayal",
"sponsor_slug": "maia-kayal",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04528082",
"publication_url": "https://clinicaltrials.gov/study/NCT04528082",
"title": "A Phase 3, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel Group Study, Followed by an Active Treatment Phase to Evaluate the Efficacy and Safety of Apremilast in Children From 2 to Less Than 18 Years of Age With Active Oral Ulcers Associated With Behçet's Disease (BEAN)",
"has_exemption": false,
"start_date": "2021-09-09",
"completion_date": "2030-02-07",
"has_results": false,
"results_due": false,
"sponsor_name": "Amgen",
"sponsor_slug": "amgen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04980872",
"publication_url": "https://clinicaltrials.gov/study/NCT04980872",
"title": "A Multicenter, Open-label, Phase 2, Extension Trial to Study the Long-term Safety in Participants With PROS or Proteus Syndrome Who Are Currently Being Treated With Miransertib in Other Studies",
"has_exemption": false,
"start_date": "2021-11-02",
"completion_date": "2030-02-07",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06799390",
"publication_url": "https://clinicaltrials.gov/study/NCT06799390",
"title": "Vagus Nerve Stimulation Following Intracerebral Hemorrhage (IHC) to Mitigate ICH-induced Inflammation and Cerebral Edema",
"has_exemption": false,
"start_date": "2025-04-06",
"completion_date": "2030-02-09",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07142343",
"publication_url": "https://clinicaltrials.gov/study/NCT07142343",
"title": "An Open-Label, Single-Arm Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Pozelimab in Pediatric Patients 1 to 5 Years of Age With CD55-Deficient Protein-Losing Enteropathy (CHAPLE Disease)",
"has_exemption": false,
"start_date": "2026-03-19",
"completion_date": "2030-02-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07204249",
"publication_url": "https://clinicaltrials.gov/study/NCT07204249",
"title": "Glutide for Ending Methamphetamine",
"has_exemption": false,
"start_date": "2026-02-26",
"completion_date": "2030-02-15",
"has_results": false,
"results_due": false,
"sponsor_name": "San Francisco Department of Public Health",
"sponsor_slug": "san-francisco-department-of-public-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07668284",
"publication_url": "https://clinicaltrials.gov/study/NCT07668284",
"title": "Evaluating the Safety and Efficacy of Coenzyme Q10 and Vitamin E Dual Therapy in Mitigating Chronic Off-Target Radiation Toxicity",
"has_exemption": false,
"start_date": "2026-12-01",
"completion_date": "2030-02-15",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Nebraska",
"sponsor_slug": "university-of-nebraska",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07539454",
"publication_url": "https://clinicaltrials.gov/study/NCT07539454",
"title": "Phase II Study of Nirogacestat in Patients With Kaposi Sarcoma",
"has_exemption": false,
"start_date": "2026-10-13",
"completion_date": "2030-02-17",
"has_results": false,
"results_due": false,
"sponsor_name": "AIDS Malignancy Consortium",
"sponsor_slug": "aids-malignancy-consortium",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07807865",
"publication_url": "https://clinicaltrials.gov/study/NCT07807865",
"title": "An Open-label, Multicenter Trial to Assess the Long-term Safety and Tolerability of ITI 1284 as Either Adjunctive or Monotherapy Treatment in Patients With Generalized Anxiety Disorder (GAD) With a History of Inadequate Response to GAD Treatment",
"has_exemption": false,
"start_date": "2026-09-03",
"completion_date": "2030-02-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Intra-Cellular Therapies, Inc.",
"sponsor_slug": "intra-cellular-therapies-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03813407",
"publication_url": "https://clinicaltrials.gov/study/NCT03813407",
"title": "An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia",
"has_exemption": false,
"start_date": "2019-04-02",
"completion_date": "2030-02-21",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07757204",
"publication_url": "https://clinicaltrials.gov/study/NCT07757204",
"title": "An Open-label Clinical Trial Investigating the Long-term Safety of Buntanetap in Treating Participants With Alzheimer's Disease",
"has_exemption": false,
"start_date": "2026-09-21",
"completion_date": "2030-02-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Annovis Bio Inc.",
"sponsor_slug": "annovis-bio-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07222800",
"publication_url": "https://clinicaltrials.gov/study/NCT07222800",
"title": "AN INTERVENTIONAL, PHASE 3, DOUBLE-BLIND, RANDOMIZED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PF-08634404 IN COMBINATION WITH CHEMOTHERAPY VERSUS BEVACIZUMAB IN COMBINATION WITH CHEMOTHERAPY IN TREATMENT-NAÏVE PARTICIPANTS WITH METASTATIC COLORECTAL CANCER",
"has_exemption": false,
"start_date": "2025-12-11",
"completion_date": "2030-02-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Pfizer",
"sponsor_slug": "pfizer",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07871825",
"publication_url": "https://clinicaltrials.gov/study/NCT07871825",
"title": "Research Protocol for a Double-Blinded Randomized Trial of Granulocyte Colony Stimulating Factor (G-CSF) for Treatment of Diminished Ovarian Reserve in Patients Undergoing In Vitro Fertilization (IVF)",
"has_exemption": false,
"start_date": "2026-02-25",
"completion_date": "2030-02-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Center for Human Reproduction",
"sponsor_slug": "center-for-human-reproduction",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07497087",
"publication_url": "https://clinicaltrials.gov/study/NCT07497087",
"title": "A Double-blind, Randomised, Placebo-controlled Trial Evaluating the Efficacy and Safety of Oral Nerandomilast Treatment in Patients With Systemic Sclerosis (SSc)",
"has_exemption": false,
"start_date": "2026-07-27",
"completion_date": "2030-02-26",
"has_results": false,
"results_due": false,
"sponsor_name": "Boehringer Ingelheim",
"sponsor_slug": "boehringer-ingelheim",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04104776",
"publication_url": "https://clinicaltrials.gov/study/NCT04104776",
"title": "A Phase 1/2 Study of DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas",
"has_exemption": false,
"start_date": "2019-09-18",
"completion_date": "2030-02-27",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT00338377",
"publication_url": "https://clinicaltrials.gov/study/NCT00338377",
"title": "Lymphodepletion Plus Adoptive Cell Transfer With or Without Dendritic Cell Immunization in Patients With Metastatic Melanoma",
"has_exemption": false,
"start_date": "2006-02-01",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT01966367",
"publication_url": "https://clinicaltrials.gov/study/NCT01966367",
"title": "CD34+ Stem Cell Selection for Patients Receiving a Matched or Partially Matched Family or Unrelated Adult Donor Allogeneic Stem Cell Transplantation for Non-Malignant Disease",
"has_exemption": false,
"start_date": "2013-03-31",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Diane George",
"sponsor_slug": "diane-george",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT02912312",
"publication_url": "https://clinicaltrials.gov/study/NCT02912312",
"title": "Shortening Adjuvant Photon Irradiation to Reduce Edema (SAPHIRE): A Randomized Trial of Hypofractionated Versus Conventionally Fractionated Regional Nodal Irradiation for Invasive Breast Cancer",
"has_exemption": false,
"start_date": "2017-02-23",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03424850",
"publication_url": "https://clinicaltrials.gov/study/NCT03424850",
"title": "A Phase I/II Dose-escalation Study Evaluating the Safety and Efficacy of 21 Gy, 23 Gy and 25 Gy for High Dose Rate (HDR) Prostate Brachytherapy",
"has_exemption": false,
"start_date": "2018-02-27",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Washington University School of Medicine",
"sponsor_slug": "washington-university-school-of-medicine",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03726554",
"publication_url": "https://clinicaltrials.gov/study/NCT03726554",
"title": "Comprehensive Reverse Shoulder: Porous Augmented Glenoid Baseplate and Mini Humeral Tray Post-Market Clinical Follow-up Study",
"has_exemption": false,
"start_date": "2018-08-28",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Zimmer Biomet",
"sponsor_slug": "zimmer-biomet",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03588975",
"publication_url": "https://clinicaltrials.gov/study/NCT03588975",
"title": "A Prospective, Open-label, Randomized, Concurrent Active-controlled, Longitudinal, Multicenter, Phase 3 Clinical Study of the Safety and Efficacy of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee",
"has_exemption": false,
"start_date": "2018-10-24",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Vericel Corporation",
"sponsor_slug": "vericel-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04408352",
"publication_url": "https://clinicaltrials.gov/study/NCT04408352",
"title": "Selective Bladder Denervation Using RF Energy for the Treatment of UUI",
"has_exemption": false,
"start_date": "2020-04-27",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Hologic, Inc.",
"sponsor_slug": "hologic-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04989803",
"publication_url": "https://clinicaltrials.gov/study/NCT04989803",
"title": "A Phase 1/2 Open-label, Multicenter Study Evaluating the Safety and Efficacy of KITE-363 or KITE-753, Autologous Anti-CD19/CD20 CAR T-cell Therapies, in Subjects With Relapsed and/or Refractory B-cell Lymphoma",
"has_exemption": false,
"start_date": "2021-10-27",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Kite, A Gilead Company",
"sponsor_slug": "kite-a-gilead-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05195905",
"publication_url": "https://clinicaltrials.gov/study/NCT05195905",
"title": "Evaluation of Spinal Cord Ischemia and Mortality and Morbidity After Endovascular Repair of Pararenal and Thoracoabdominal Aortic Aneurysm Using Surgeon-Modified Endografts",
"has_exemption": false,
"start_date": "2023-06-06",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Konstantinos Arnaoutakis, MD",
"sponsor_slug": "konstantinos-arnaoutakis-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06433635",
"publication_url": "https://clinicaltrials.gov/study/NCT06433635",
"title": "Sequential Multiple Assignment Randomized Trial for Bipolar Depression",
"has_exemption": false,
"start_date": "2024-10-01",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06528314",
"publication_url": "https://clinicaltrials.gov/study/NCT06528314",
"title": "A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH",
"has_exemption": false,
"start_date": "2024-10-04",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Akero Therapeutics, Inc",
"sponsor_slug": "akero-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06895785",
"publication_url": "https://clinicaltrials.gov/study/NCT06895785",
"title": "Exalt Single-use Duodenoscope Vs Reusable Scope, a Randomized Controlled Trial",
"has_exemption": false,
"start_date": "2025-02-21",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Rush University Medical Center",
"sponsor_slug": "rush-university-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06839976",
"publication_url": "https://clinicaltrials.gov/study/NCT06839976",
"title": "CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Adolescents and Young Adults With Systemic Lupus Erythematosus (SLE)",
"has_exemption": false,
"start_date": "2025-05-06",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Hospital of Philadelphia",
"sponsor_slug": "childrens-hospital-of-philadelphia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06903923",
"publication_url": "https://clinicaltrials.gov/study/NCT06903923",
"title": "Bone Metabolism in Adolescents Undergoing GLP-1 Receptor Agonist Therapy",
"has_exemption": false,
"start_date": "2025-07-31",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Virginia",
"sponsor_slug": "university-of-virginia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07003997",
"publication_url": "https://clinicaltrials.gov/study/NCT07003997",
"title": "Janus Kinase (JAK) Signaling in Depression",
"has_exemption": false,
"start_date": "2025-09-03",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Emory University",
"sponsor_slug": "emory-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07278505",
"publication_url": "https://clinicaltrials.gov/study/NCT07278505",
"title": "Pathophysiological Mechanisms of Cannabidiol in Stress Regulation",
"has_exemption": false,
"start_date": "2025-10-29",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Icahn School of Medicine at Mount Sinai",
"sponsor_slug": "icahn-school-of-medicine-at-mount-sinai",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06990269",
"publication_url": "https://clinicaltrials.gov/study/NCT06990269",
"title": "A Phase 2, Randomized, Masked, Placebo-Controlled Study of Subcutaneously Administered ADX-038 in Participants With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)",
"has_exemption": false,
"start_date": "2025-11-10",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "ADARx Pharmaceuticals, Inc.",
"sponsor_slug": "adarx-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06890338",
"publication_url": "https://clinicaltrials.gov/study/NCT06890338",
"title": "A Single-Arm, Phase 2 Study of Neoadjuvant Carboplatin and Mirvetuximab Soravtansine in Subjects With FRα-Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer",
"has_exemption": false,
"start_date": "2025-11-21",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06686771",
"publication_url": "https://clinicaltrials.gov/study/NCT06686771",
"title": "Consolidative Use of Radiotherapy to Block (CURB2) Oligoprogression In Patients With Metastatic Non-Small-Cell Lung Cancer",
"has_exemption": false,
"start_date": "2025-12-16",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Canadian Cancer Trials Group",
"sponsor_slug": "canadian-cancer-trials-group",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07278557",
"publication_url": "https://clinicaltrials.gov/study/NCT07278557",
"title": "Assessment of Sparing Parotid Ducts Via MRI Sialography for Reduced Patient-Reported Xerostomia Following Radiotherapy for Oropharynx Cancer",
"has_exemption": false,
"start_date": "2026-01-28",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "UNC Lineberger Comprehensive Cancer Center",
"sponsor_slug": "unc-lineberger-comprehensive-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07225075",
"publication_url": "https://clinicaltrials.gov/study/NCT07225075",
"title": "Pivotal Study of the Silk Vista Baby Flow Diverters in the Treatment of Unruptured Intracranial Aneurysms (PIONEER)",
"has_exemption": false,
"start_date": "2026-02-04",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Balt USA",
"sponsor_slug": "balt-usa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06625190",
"publication_url": "https://clinicaltrials.gov/study/NCT06625190",
"title": "Allogeneic Stem Cell Transplantation Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion With Zoledronic Acid in Combination to Treat Pediatric, Adolescent, and Young Adult Patients With Relapsed/Refractory Solid Tumors",
"has_exemption": false,
"start_date": "2026-02-11",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Florida",
"sponsor_slug": "university-of-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07300956",
"publication_url": "https://clinicaltrials.gov/study/NCT07300956",
"title": "Comparing Medication Treatments for Neurodevelopmental Differences in Young Children on Rates of Beneficial Response",
"has_exemption": false,
"start_date": "2026-02-16",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Hospital Medical Center, Cincinnati",
"sponsor_slug": "childrens-hospital-medical-center-cincinnati",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07318480",
"publication_url": "https://clinicaltrials.gov/study/NCT07318480",
"title": "Cognitively-enhanced tDCS of the Dorsolateral Prefrontal Cortex to Reduce Craving in Cocaine Addiction",
"has_exemption": false,
"start_date": "2026-02-25",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Icahn School of Medicine at Mount Sinai",
"sponsor_slug": "icahn-school-of-medicine-at-mount-sinai",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07290621",
"publication_url": "https://clinicaltrials.gov/study/NCT07290621",
"title": "Phase II Trial of Neoadjuvant Toripalimab in Combination With Chemotherapy Followed by Transoral Robotic Surgery or Risk/Response Stratified Chemoradiotherapy for Locoregional HPV16+ Oropharyngeal Cancer: TARGET HPV Cohort 2",
"has_exemption": false,
"start_date": "2026-02-28",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Chicago",
"sponsor_slug": "university-of-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06871488",
"publication_url": "https://clinicaltrials.gov/study/NCT06871488",
"title": "Identification of Neural Markers of Aggression and Irritability and Their Capacity to Predict Treatment Response to CNS Stimulant Medication in Youth With ADHD",
"has_exemption": false,
"start_date": "2026-03-05",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Milton S. Hershey Medical Center",
"sponsor_slug": "milton-s-hershey-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07459647",
"publication_url": "https://clinicaltrials.gov/study/NCT07459647",
"title": "An Open-Label Study to Assess the Long-Term Safety, Tolerability, and Effectiveness of ML-007C-MA in Adult Participants With Schizophrenia",
"has_exemption": false,
"start_date": "2026-03-31",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "MapLight Therapeutics",
"sponsor_slug": "maplight-therapeutics",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07318714",
"publication_url": "https://clinicaltrials.gov/study/NCT07318714",
"title": "A Phase 1/2 Multicenter, Open-label, Dose Escalation Study Followed by a Randomized, Double-blind Sham-controlled Dose Expansion Study to Evaluate the Safety, Tolerability and Efficacy of ASP2246 in Adult Participants Who Have Motor Dysfunction Associated With Late Subacute to Chronic Ischemic Stroke Due to Supratentorial Perforator Area Infarction",
"has_exemption": false,
"start_date": "2026-04-03",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Astellas Pharma Inc",
"sponsor_slug": "astellas-pharma-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07226869",
"publication_url": "https://clinicaltrials.gov/study/NCT07226869",
"title": "Computer Guided Microwave Liver Ablation",
"has_exemption": false,
"start_date": "2026-05-08",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "NE Scientific INC",
"sponsor_slug": "ne-scientific-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06824649",
"publication_url": "https://clinicaltrials.gov/study/NCT06824649",
"title": "SMART Use of Biologics in Chronic Rhinosinusitis With Nasal Polyposis",
"has_exemption": false,
"start_date": "2026-06-03",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University of South Carolina",
"sponsor_slug": "medical-university-of-south-carolina",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07731750",
"publication_url": "https://clinicaltrials.gov/study/NCT07731750",
"title": "Algorithm-informed Decision-making to Advance Pain Treatment (ADAPT Study)",
"has_exemption": false,
"start_date": "2026-07-23",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan",
"sponsor_slug": "university-of-michigan",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07455903",
"publication_url": "https://clinicaltrials.gov/study/NCT07455903",
"title": "Assessing the Efficacy of Neoadjuvant Androgen Deprivation Therapy (ADT) Utilizing 18F-Flotufolastat PSMA PET/CT in Patients With High-Risk Localized Prostate Cancer (LHRPC)",
"has_exemption": false,
"start_date": "2026-07-29",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Baptist Health South Florida",
"sponsor_slug": "baptist-health-south-florida",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07601295",
"publication_url": "https://clinicaltrials.gov/study/NCT07601295",
"title": "A Phase II, Randomized, Double-Blind, Safety and Efficacy Study of Tiprelestat Versus Placebo When Added to Standard of Care for the Treatment of Pulmonary Arterial Hypertension (PAH)",
"has_exemption": false,
"start_date": "2026-07-31",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Stanford University",
"sponsor_slug": "stanford-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07730021",
"publication_url": "https://clinicaltrials.gov/study/NCT07730021",
"title": "A Phase 1b/2 Study of ASP388B as Monotherapy and in Combination With Standard Therapies in Participants With Locally Advanced Unresectable or Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2026-09-02",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Astellas Pharma Global Development, Inc.",
"sponsor_slug": "astellas-pharma-global-development-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07588568",
"publication_url": "https://clinicaltrials.gov/study/NCT07588568",
"title": "A Trial of Upadacitinib for Non-responsive Eosinophilic Esophagitis (ATUNE)",
"has_exemption": false,
"start_date": "2026-09-30",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "University of North Carolina, Chapel Hill",
"sponsor_slug": "university-of-north-carolina-chapel-hill",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07796646",
"publication_url": "https://clinicaltrials.gov/study/NCT07796646",
"title": "An Open-Label Extension Study to Evaluate the Long-Term Safety and Tolerability of Ultevursen in Participants With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene",
"has_exemption": false,
"start_date": "2026-10-05",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Laboratoires Thea",
"sponsor_slug": "laboratoires-thea",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07460375",
"publication_url": "https://clinicaltrials.gov/study/NCT07460375",
"title": "A First-in-Human Phase 1/2, Dose Escalation and Dose Expansion Study to Evaluate Safety, Tolerability, and Preliminary Efficacy of Claudin18.2 (CLDN18.2)-Directed Antibody-Drug Conjugate (ADC) LCB02A in Patients With CLDN18.2-positive Advanced Solid Tumors",
"has_exemption": false,
"start_date": "2026-10-14",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "LigaChem Biosciences, Inc.",
"sponsor_slug": "ligachem-biosciences-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07129759",
"publication_url": "https://clinicaltrials.gov/study/NCT07129759",
"title": "A Long-term Extension Study to Evaluate the Safety and Tolerability of Daily Oral LUM-201 in Children With Growth Hormone Deficiency (GHD)",
"has_exemption": false,
"start_date": "2027-02-28",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Lumos Pharma",
"sponsor_slug": "lumos-pharma",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07206849",
"publication_url": "https://clinicaltrials.gov/study/NCT07206849",
"title": "A Phase 2 Study of Tovorafenib in Pediatric and Young Adult Patients Newly Diagnosed With High-Grade Glioma (HGG), Including Diffuse Intrinsic Pontine Glioma (DIPG), Which Harbor Alterations in the Mitogen-Activated Protein Kinase (MAPK) Pathway",
"has_exemption": false,
"start_date": "2027-02-28",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Nationwide Children's Hospital",
"sponsor_slug": "nationwide-childrens-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07825389",
"publication_url": "https://clinicaltrials.gov/study/NCT07825389",
"title": "Multi-center, Phase 1b/2 Clinical Study of an Autologous Anti-CD20/BCMA Chimeric Antigen Receptor T-Cell Therapy (C-CAR168) for the Treatment of Progressive Multiple Sclerosis Refractory to Standard Therapy",
"has_exemption": false,
"start_date": "2027-02-28",
"completion_date": "2030-02-28",
"has_results": false,
"results_due": false,
"sponsor_name": "AbelZeta, Inc.",
"sponsor_slug": "abelzeta-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04671771",
"publication_url": "https://clinicaltrials.gov/study/NCT04671771",
"title": "A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease",
"has_exemption": false,
"start_date": "2020-12-03",
"completion_date": "2030-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "W.L.Gore & Associates",
"sponsor_slug": "wlgore-associates",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06179888",
"publication_url": "https://clinicaltrials.gov/study/NCT06179888",
"title": "Randomized Phase 2 Study of Iberdomide Maintenance Therapy Following Idecabtagene Vicleucel CAR-T in Multiple Myeloma Patients",
"has_exemption": false,
"start_date": "2024-08-27",
"completion_date": "2030-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06563596",
"publication_url": "https://clinicaltrials.gov/study/NCT06563596",
"title": "A Phase 2 Study of Epcoritamab, Zanubrutinib, and Rituximab (EZR) for Treatment of Relapsed or Refractory Follicular Lymphoma or Marginal Zone Lymphoma",
"has_exemption": false,
"start_date": "2025-01-21",
"completion_date": "2030-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Reid Merryman, MD",
"sponsor_slug": "reid-merryman-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06532123",
"publication_url": "https://clinicaltrials.gov/study/NCT06532123",
"title": "Mechanisms of Improving Fecal Continence Muscles Motor Function in Health and Disease",
"has_exemption": false,
"start_date": "2025-07-15",
"completion_date": "2030-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical College of Wisconsin",
"sponsor_slug": "medical-college-of-wisconsin",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04774536",
"publication_url": "https://clinicaltrials.gov/study/NCT04774536",
"title": "Transplantation of CRISPRCas9 Corrected Hematopoietic Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease",
"has_exemption": false,
"start_date": "2025-08-22",
"completion_date": "2030-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Mark Walters, MD",
"sponsor_slug": "mark-walters-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07591649",
"publication_url": "https://clinicaltrials.gov/study/NCT07591649",
"title": "Safety and Efficacy of Expanded KIR-HLA Mismatched Natural Killer Cell Immunotherapy (AdaptNK) for High-Risk Myeloid Diseases as Bridge to Allogeneic Hematopoietic Stem Cell Transplantation",
"has_exemption": false,
"start_date": "2026-05-08",
"completion_date": "2030-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Masonic Cancer Center, University of Minnesota",
"sponsor_slug": "masonic-cancer-center-university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07382596",
"publication_url": "https://clinicaltrials.gov/study/NCT07382596",
"title": "Cervical Plexus Hydrodissection With D5W Versus NS for Treatment-Resistant PTSD",
"has_exemption": false,
"start_date": "2026-05-16",
"completion_date": "2030-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Dr. Dean Reeves Clinic",
"sponsor_slug": "dr-dean-reeves-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06965114",
"publication_url": "https://clinicaltrials.gov/study/NCT06965114",
"title": "A Phase 1 Study of Combination Tovorafenib (DAY101) and Rituximab Treatment in Relapsed or Refractory Classical Hairy Cell Leukemia and Phase 2 Randomized Study Comparing Tovorafenib (DAY101) and Rituximab With Cladribine and Rituximab for Front-Line Treatment of Classical Hairy Cell Leukemia",
"has_exemption": false,
"start_date": "2026-05-29",
"completion_date": "2030-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07679282",
"publication_url": "https://clinicaltrials.gov/study/NCT07679282",
"title": "Comparative Effectiveness of Positive Airway Pressure Therapy, Dental Device, and Atomoxetine-Oxybutynin for Sleep Apnea: the ADAPT-OSA Study",
"has_exemption": false,
"start_date": "2026-09-04",
"completion_date": "2030-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Sairam Parthasarathy",
"sponsor_slug": "sairam-parthasarathy",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05713799",
"publication_url": "https://clinicaltrials.gov/study/NCT05713799",
"title": "Phase II Trial of the Combination of Alpha-lipoic Acid and Mirabegron in Women and in Men With Obesity",
"has_exemption": false,
"start_date": "2026-10-25",
"completion_date": "2030-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
"sponsor_slug": "national-institute-of-diabetes-and-digestive-and-kidney-diseases-niddk",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04200729",
"publication_url": "https://clinicaltrials.gov/study/NCT04200729",
"title": "Povidone-iodine Irrigation for Prevention of Intra-abdominal Abscess in Pediatric Perforated Appendicitis",
"has_exemption": false,
"start_date": "2027-03-01",
"completion_date": "2030-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "The University of Texas Health Science Center, Houston",
"sponsor_slug": "the-university-of-texas-health-science-center-houston",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07313800",
"publication_url": "https://clinicaltrials.gov/study/NCT07313800",
"title": "Enduring Migraine Benefit From Responsive Artery Coil Embolization (EMBRACE): A Single-Site, Non-Significant Risk Pilot Study of Middle Meningeal Artery Embolization Using FDA-Cleared Coils for Refractory Episodic Migraine",
"has_exemption": false,
"start_date": "2028-03-01",
"completion_date": "2030-03-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Cortex Neurovascular",
"sponsor_slug": "cortex-neurovascular",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05285527",
"publication_url": "https://clinicaltrials.gov/study/NCT05285527",
"title": "MiSight 1 Day Safety Post-Approval Study",
"has_exemption": false,
"start_date": "2022-08-15",
"completion_date": "2030-03-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Coopervision, Inc.",
"sponsor_slug": "coopervision-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05215340",
"publication_url": "https://clinicaltrials.gov/study/NCT05215340",
"title": "A Randomized, Open-label, Phase 3 Trial of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in Treatment-naïve Subjects With Advanced or Metastatic PD-L1 High (TPS ≥50%) Non-small Cell Lung Cancer Without Actionable Genomic Alterations (TROPION-Lung08)",
"has_exemption": false,
"start_date": "2022-03-04",
"completion_date": "2030-03-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Daiichi Sankyo",
"sponsor_slug": "daiichi-sankyo",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05952557",
"publication_url": "https://clinicaltrials.gov/study/NCT05952557",
"title": "CAMBRIA-2: A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Camizestrant (AZD9833, a Next Generation, Oral Selective Estrogen Receptor Degrader) vs Standard Endocrine Therapy (Aromatase Inhibitor or Tamoxifen) as Adjuvant Treatment for Patients With ER+/HER2- Early Breast Cancer and an Intermediate-High or High Risk of Recurrence Who Have Completed Definitive Locoregional Treatment and Have No Evidence of Disease",
"has_exemption": false,
"start_date": "2023-10-05",
"completion_date": "2030-03-04",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07459673",
"publication_url": "https://clinicaltrials.gov/study/NCT07459673",
"title": "HERizon-Breast: A ctDNA-Guided Adaptive Study of Sequential Anti-HER2 Therapies and CNS Prophylaxis to Induce Long-Term Remission",
"has_exemption": false,
"start_date": "2026-03-04",
"completion_date": "2030-03-04",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06869551",
"publication_url": "https://clinicaltrials.gov/study/NCT06869551",
"title": "A Phase 3, Multicenter, Double-blind, Placebo-controlled, Randomized Withdrawal Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of Deucravacitinib in Children and Adolescents From 5 to Less Than 18 Years of Age With Active Juvenile Psoriatic Arthritis",
"has_exemption": false,
"start_date": "2025-03-13",
"completion_date": "2030-03-06",
"has_results": false,
"results_due": false,
"sponsor_name": "Bristol-Myers Squibb",
"sponsor_slug": "bristol-myers-squibb",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05837897",
"publication_url": "https://clinicaltrials.gov/study/NCT05837897",
"title": "A Phase 3, Multicenter, Randomized, Parallel-Group, Double-blind, Placebo-Controlled Induction Study Followed by an Open-label Extension Period to Evaluate the Efficacy and Safety of Intravenous Vedolizumab (300 mg) Infusion Treatment in Subjects in China With Moderately to Severely Active Crohn's Disease",
"has_exemption": false,
"start_date": "2023-06-16",
"completion_date": "2030-03-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07424404",
"publication_url": "https://clinicaltrials.gov/study/NCT07424404",
"title": "A Phase 3 Multicenter, Open-label Study to Assess the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride in Children and Adolescents With Psychiatric Disorders",
"has_exemption": false,
"start_date": "2026-04-07",
"completion_date": "2030-03-08",
"has_results": false,
"results_due": false,
"sponsor_name": "Karuna Therapeutics, Inc., a Bristol Myers Squibb company",
"sponsor_slug": "karuna-therapeutics-inc-a-bristol-myers-squibb-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04544592",
"publication_url": "https://clinicaltrials.gov/study/NCT04544592",
"title": "Phase I/II Dose Escalation and Preliminary Efficacy of CD19 Directed CAR-T Cells Generated Using the Miltenyi CliniMACs Prodigy System (UCD19 CAR-T) in Pediatric Patients With Relapsed and/or Refractory B-Cell Acute Lymphoblastic Leukemia (B-ALL) and B-Cell Non-Hodgkin Lymphoma (B-NHL)",
"has_exemption": false,
"start_date": "2021-03-10",
"completion_date": "2030-03-10",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05646381",
"publication_url": "https://clinicaltrials.gov/study/NCT05646381",
"title": "A Randomized Double-blind, Placebo-controlled, Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis [Lp(a)FRONTIERS CAVS]",
"has_exemption": false,
"start_date": "2024-03-07",
"completion_date": "2030-03-12",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07483307",
"publication_url": "https://clinicaltrials.gov/study/NCT07483307",
"title": "Impact of Neoadjuvant Endocrine Therapy on Surgical Outcomes in Patients With Stage 2 to 3 Invasive Lobular Carcinoma: A Prospective Study",
"has_exemption": false,
"start_date": "2026-03-13",
"completion_date": "2030-03-13",
"has_results": false,
"results_due": false,
"sponsor_name": "Memorial Sloan Kettering Cancer Center",
"sponsor_slug": "memorial-sloan-kettering-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06987539",
"publication_url": "https://clinicaltrials.gov/study/NCT06987539",
"title": "A Phase 2 Open-label Multicenter Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inebilizumab in Children From 2 Years to Less Than 18 Years of Age With Generalized Myasthenia Gravis (gMG)",
"has_exemption": false,
"start_date": "2026-07-21",
"completion_date": "2030-03-13",
"has_results": false,
"results_due": false,
"sponsor_name": "Amgen",
"sponsor_slug": "amgen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06921785",
"publication_url": "https://clinicaltrials.gov/study/NCT06921785",
"title": "A Phase III, Randomised, Open-label, Sponsor-blinded, Multicentre Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma",
"has_exemption": false,
"start_date": "2025-05-06",
"completion_date": "2030-03-15",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07527910",
"publication_url": "https://clinicaltrials.gov/study/NCT07527910",
"title": "A Two-Part, Phase 2a, Randomized, Double-Blind, Placebo-Controlled Study of ALN-PNP With and Without a GLP1R Agonist in Adults With Homozygous PNPLA3-Related Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)",
"has_exemption": false,
"start_date": "2026-05-22",
"completion_date": "2030-03-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06565507",
"publication_url": "https://clinicaltrials.gov/study/NCT06565507",
"title": "A Double-blind Multicenter, Randomized Controlled Trial of Single and Multiple Dose Regimens of Oxfendazole for Mild (One or Two Lesions) Parenchymal Brain Cysticercosis, With an Open Comparison Group",
"has_exemption": false,
"start_date": "2026-12-01",
"completion_date": "2030-03-15",
"has_results": false,
"results_due": false,
"sponsor_name": "Universidad Peruana Cayetano Heredia",
"sponsor_slug": "universidad-peruana-cayetano-heredia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05691478",
"publication_url": "https://clinicaltrials.gov/study/NCT05691478",
"title": "A Feasibility and Randomized Phase 2/3 Study of the VEGFR2/MET Inhibitor Cabozantinib in Combination With Cytotoxic Chemotherapy for Newly Diagnosed Osteosarcoma",
"has_exemption": false,
"start_date": "2023-03-03",
"completion_date": "2030-03-20",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06042569",
"publication_url": "https://clinicaltrials.gov/study/NCT06042569",
"title": "Dose Reduction of Docetaxel-Based Chemotherapy in Vulnerable Older Women With Early-Stage Breast Cancer (DOROTHY)",
"has_exemption": false,
"start_date": "2024-09-16",
"completion_date": "2030-03-20",
"has_results": false,
"results_due": false,
"sponsor_name": "City of Hope Medical Center",
"sponsor_slug": "city-of-hope-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07178301",
"publication_url": "https://clinicaltrials.gov/study/NCT07178301",
"title": "Elective Neck Dosing in Low Risk Oropharyngeal Human Papillomavirus-Related Cancer Treatment (ENLIGHT): A Single Arm Prospective Phase II Assessing 30 Gy Elective Neck Dose",
"has_exemption": false,
"start_date": "2025-12-05",
"completion_date": "2030-03-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Northwestern University",
"sponsor_slug": "northwestern-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07253285",
"publication_url": "https://clinicaltrials.gov/study/NCT07253285",
"title": "Efficacy, Safety and Pharmacokinetics of Cagrilintide s.c. 2.4 mg as Monotherapy and in Combination With Semaglutide s.c. 2.4 mg (CagriSema) Once Weekly for Weight Management in Chidren and Adolescents With Overweight or Obesity",
"has_exemption": false,
"start_date": "2026-01-08",
"completion_date": "2030-03-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Novo Nordisk A/S",
"sponsor_slug": "novo-nordisk-as",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07789015",
"publication_url": "https://clinicaltrials.gov/study/NCT07789015",
"title": "A Phase III, Parallel Design, Double-blind, Randomised, Placebo-controlled, Multi-centre Trial to Evaluate the Efficacy and Safety of Nerandomilast Oral Therapy Added to Standard Background Therapy Over 52 Weeks in Adult Trial Participants With Active Idiopathic Inflammatory Myopathies (VERANDA™-IIM)",
"has_exemption": false,
"start_date": "2026-12-14",
"completion_date": "2030-03-21",
"has_results": false,
"results_due": false,
"sponsor_name": "Boehringer Ingelheim",
"sponsor_slug": "boehringer-ingelheim",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05753306",
"publication_url": "https://clinicaltrials.gov/study/NCT05753306",
"title": "A Phase II Study of Robotic Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Patients With Gastric Cancer and Limited Peritoneal Metastasis: ROBO-CHIP Trial",
"has_exemption": false,
"start_date": "2023-04-20",
"completion_date": "2030-03-25",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05125016",
"publication_url": "https://clinicaltrials.gov/study/NCT05125016",
"title": "Phase 1/2 Study of REGN4336 (a PSMAxCD3 Bispecific Antibody) Administered Alone or in Combination With REGN5678 (a PSMAxCD28 Bispecific Antibody) in Patients With Metastatic Castration-Resistant Prostate Cancer",
"has_exemption": false,
"start_date": "2021-11-30",
"completion_date": "2030-03-28",
"has_results": false,
"results_due": false,
"sponsor_name": "Regeneron Pharmaceuticals",
"sponsor_slug": "regeneron-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07446855",
"publication_url": "https://clinicaltrials.gov/study/NCT07446855",
"title": "A Modular Open-label, Phase I/IIa Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of Ascending Doses of AZD4956 as Monotherapy, and in Combination With Anti-Cancer Agents in Participants With Advanced/Metastatic Homologous Recombination Repair Defective Solid Tumours",
"has_exemption": false,
"start_date": "2026-03-17",
"completion_date": "2030-03-29",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06439693",
"publication_url": "https://clinicaltrials.gov/study/NCT06439693",
"title": "A Single-Arm, Phase II Study of Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer: The SAPPHO Study",
"has_exemption": false,
"start_date": "2024-08-08",
"completion_date": "2030-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "Dana-Farber Cancer Institute",
"sponsor_slug": "dana-farber-cancer-institute",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07673328",
"publication_url": "https://clinicaltrials.gov/study/NCT07673328",
"title": "Enhancing Voluntary Motion in Broad Patient Populations With Modular Powered Orthoses Renewal",
"has_exemption": false,
"start_date": "2025-07-18",
"completion_date": "2030-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Michigan",
"sponsor_slug": "university-of-michigan",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07843537",
"publication_url": "https://clinicaltrials.gov/study/NCT07843537",
"title": "MINTER Trial: Metal Intervention aNd ThErapy With Radiotherapy In Thoracic Cancer Using Copper Donor Therapy: A Phase 2, Open-Label Study",
"has_exemption": false,
"start_date": "2027-03-01",
"completion_date": "2030-03-30",
"has_results": false,
"results_due": false,
"sponsor_name": "M.D. Anderson Cancer Center",
"sponsor_slug": "md-anderson-cancer-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT02050113",
"publication_url": "https://clinicaltrials.gov/study/NCT02050113",
"title": "Complex Aortic Aneurysm Repair Using Physician Modified Endografts and Custom Made Devices",
"has_exemption": false,
"start_date": "2014-03-31",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Andres Schanzer",
"sponsor_slug": "andres-schanzer",
"status": "ongoing",
"is_pact": true,
"days_late": null
},
{
"registry_id": "NCT03048201",
"publication_url": "https://clinicaltrials.gov/study/NCT03048201",
"title": "Post-market Registry Study on the Physica System Total Knee Replacement",
"has_exemption": false,
"start_date": "2017-03-24",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Limacorporate S.p.a",
"sponsor_slug": "limacorporate-spa",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03674372",
"publication_url": "https://clinicaltrials.gov/study/NCT03674372",
"title": "Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Severe Right and Left Congenital Diaphragmatic Hernia (CDH)",
"has_exemption": false,
"start_date": "2018-11-16",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Colorado, Denver",
"sponsor_slug": "university-of-colorado-denver",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04683250",
"publication_url": "https://clinicaltrials.gov/study/NCT04683250",
"title": "Phase I/II Study of the Selective RET Inhibitor TAS0953/HM06 in Patients With Advanced Solid Tumors With RET Gene Abnormalities",
"has_exemption": false,
"start_date": "2020-12-16",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Taiho Pharmaceutical Co., Ltd.",
"sponsor_slug": "taiho-pharmaceutical-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05491525",
"publication_url": "https://clinicaltrials.gov/study/NCT05491525",
"title": "A Phase 2/3, Open-label, Baseline-controlled, Multicenter, Long-term Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With Neurogenic Detrusor Overactivity (NDO) on Clean Intermittent Catheterization (CIC)",
"has_exemption": false,
"start_date": "2022-10-12",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Urovant Sciences GmbH",
"sponsor_slug": "urovant-sciences-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05286801",
"publication_url": "https://clinicaltrials.gov/study/NCT05286801",
"title": "A Phase 1/2 Study of Tiragolumab (NSC# 827799) and Atezolizumab (NSC# 783608) in Patients With Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors",
"has_exemption": false,
"start_date": "2022-11-17",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "National Cancer Institute (NCI)",
"sponsor_slug": "national-cancer-institute-nci",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05259527",
"publication_url": "https://clinicaltrials.gov/study/NCT05259527",
"title": "Impact of Vitamin D Supplementation on Reported Rates of Taxane-Induced Neuropathy",
"has_exemption": false,
"start_date": "2022-12-19",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Virginia Commonwealth University",
"sponsor_slug": "virginia-commonwealth-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05645536",
"publication_url": "https://clinicaltrials.gov/study/NCT05645536",
"title": "Open-label, Safety Extension Study for Subjects With HR+, HER2-Negative Breast Cancer Who Have Completed the OVarian Suppression Evaluating Subcutaneous LeuprolIde Acetate in Breast Cancer OVELIA Study",
"has_exemption": false,
"start_date": "2022-12-28",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Tolmar Inc.",
"sponsor_slug": "tolmar-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06153173",
"publication_url": "https://clinicaltrials.gov/study/NCT06153173",
"title": "A Phase II Trial of the MEK Inhibitor Mirdametinib in Histiocytic Disorders",
"has_exemption": false,
"start_date": "2024-02-05",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Children's Hospital Medical Center, Cincinnati",
"sponsor_slug": "childrens-hospital-medical-center-cincinnati",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06274528",
"publication_url": "https://clinicaltrials.gov/study/NCT06274528",
"title": "Effect of a Dual Orexin Receptor Antagonist on CSF Alzheimer's Disease Biomarkers",
"has_exemption": false,
"start_date": "2024-03-11",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Minnesota",
"sponsor_slug": "university-of-minnesota",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06013865",
"publication_url": "https://clinicaltrials.gov/study/NCT06013865",
"title": "An Exploratory Investigation of the Safety of Empagliflozin in Kidney Transplant Recipients (SEKTR)",
"has_exemption": false,
"start_date": "2024-04-05",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06424756",
"publication_url": "https://clinicaltrials.gov/study/NCT06424756",
"title": "Role of Mitochondria-derived Oxidative Stress on Microvascular Endothelial Function in Healthy Non-Hispanic Black and White Adults",
"has_exemption": false,
"start_date": "2024-07-01",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Georgia",
"sponsor_slug": "university-of-georgia",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06802315",
"publication_url": "https://clinicaltrials.gov/study/NCT06802315",
"title": "A Phase II Study of Intensity Modulated Total Marrow Irradiation (IM-TMI) in Addition to Myeloablative Fludarabine/Busulfan and Post-Transplant Cyclophosphamide (PTCY) for Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk AML, CML, and MDS",
"has_exemption": false,
"start_date": "2025-02-04",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Illinois at Chicago",
"sponsor_slug": "university-of-illinois-at-chicago",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06965582",
"publication_url": "https://clinicaltrials.gov/study/NCT06965582",
"title": "A Pilot Study Of The ALPFA Benign Prostatic Hyperplasia (BPH) Pulsed Field Ablation (PFA) System In Men With Symptomatic Benign Prostatic Hyperplasia",
"has_exemption": false,
"start_date": "2025-02-07",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "ALPFA Medical",
"sponsor_slug": "alpfa-medical",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06926790",
"publication_url": "https://clinicaltrials.gov/study/NCT06926790",
"title": "Neoadjuvant Nivolumab Plus Ipilimumab in Resectable Non-small Cell Lung Cancer",
"has_exemption": false,
"start_date": "2025-02-17",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "The First Affiliated Hospital of Guangzhou Medical University",
"sponsor_slug": "the-first-affiliated-hospital-of-guangzhou-medical-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06805305",
"publication_url": "https://clinicaltrials.gov/study/NCT06805305",
"title": "Randomized Study of DOC1021 Dendritic Cell Immunotherapy in Combination With Standard of Care for Newly Diagnosed Adult Glioblastoma",
"has_exemption": false,
"start_date": "2025-03-17",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Diakonos Oncology Corporation",
"sponsor_slug": "diakonos-oncology-corporation",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06847269",
"publication_url": "https://clinicaltrials.gov/study/NCT06847269",
"title": "CAR T CELL Therapy for Pediatric, Adolescent and Young Adult Patients With CD19-Positive Leukemia: An Investigation of Lymphodepleting Chemotherapy Pharmacokinetics",
"has_exemption": false,
"start_date": "2025-05-21",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "St. Jude Children's Research Hospital",
"sponsor_slug": "st-jude-childrens-research-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07076342",
"publication_url": "https://clinicaltrials.gov/study/NCT07076342",
"title": "Mechanistic Clinical Trial Evaluating the Role of the Metabotropic Glutamate Receptor Subtype 5 (mGluR5) in the Antidepressant Mechanism of Cognitive Behavioral Therapy for Insomnia (CBT-I)",
"has_exemption": false,
"start_date": "2025-08-01",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Stony Brook University",
"sponsor_slug": "stony-brook-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07193511",
"publication_url": "https://clinicaltrials.gov/study/NCT07193511",
"title": "A Phase 1/2, First-in-Human Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of AVZO-103, a Nectin4/Trop2 ADC, as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Urothelial Cancer or Other Solid Tumors",
"has_exemption": false,
"start_date": "2025-10-02",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Avenzo Therapeutics, Inc.",
"sponsor_slug": "avenzo-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06937866",
"publication_url": "https://clinicaltrials.gov/study/NCT06937866",
"title": "Maintenance Zanzalintinib With Oral Etoposide Following High-dose Chemotherapy in Patients With Relapsed Metastatic Germ-cell Tumor",
"has_exemption": false,
"start_date": "2025-11-12",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Indiana University",
"sponsor_slug": "indiana-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07169279",
"publication_url": "https://clinicaltrials.gov/study/NCT07169279",
"title": "Phase 2b, Randomized, Double-Blind, Placebo-Controlled Clinical Trial, Preceded by a Single Ascending Dose Portion and a Phase 2 Open-Label Portion, to Evaluate the Safety and Efficacy of Oral Infigratinib in Infants and Young Children With Achondroplasia",
"has_exemption": false,
"start_date": "2025-11-19",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "QED Therapeutics, a BridgeBio company",
"sponsor_slug": "qed-therapeutics-a-bridgebio-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07108270",
"publication_url": "https://clinicaltrials.gov/study/NCT07108270",
"title": "A Phase 2, Multicenter, Open-label, Single Arm Study of Dostarlimab Plus Carboplatin-paclitaxel Followed by Dostarlimab Monotherapy in Participants With dMMR/MSI-H Primary Advanced or Recurrent Endometrial Cancer in China (China RUBY)",
"has_exemption": false,
"start_date": "2025-11-27",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "GlaxoSmithKline",
"sponsor_slug": "glaxosmithkline",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07159841",
"publication_url": "https://clinicaltrials.gov/study/NCT07159841",
"title": "A Phase 2/3 Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Atumelnant Treatment in Pediatric Participants With Congenital Adrenal Hyperplasia Including a Long-Term Extension",
"has_exemption": false,
"start_date": "2026-01-22",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Crinetics Pharmaceuticals Inc.",
"sponsor_slug": "crinetics-pharmaceuticals-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07286006",
"publication_url": "https://clinicaltrials.gov/study/NCT07286006",
"title": "A Long-Term Extension Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 in Adult Patients With Graves' Disease",
"has_exemption": false,
"start_date": "2026-01-26",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Immunovant Sciences GmbH",
"sponsor_slug": "immunovant-sciences-gmbh",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07432295",
"publication_url": "https://clinicaltrials.gov/study/NCT07432295",
"title": "A Randomized, Multicenter, Open-Label, Phase 2 Study of Givastomig (TJ033721) in Combination With Nivolumab and Chemotherapy Versus Nivolumab and Chemotherapy in Participants With Previously Untreated CLDN18.2 Positive and PD-1L Positive Locally Advanced or Metastatic Gastric, Esophageal, or Gastroesophageal Junction Adenocarcinoma",
"has_exemption": false,
"start_date": "2026-02-11",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "I-Mab Biopharma US Limited",
"sponsor_slug": "i-mab-biopharma-us-limited",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07284758",
"publication_url": "https://clinicaltrials.gov/study/NCT07284758",
"title": "A Phase 2, Open-Label, Single-Arm, Multicenter Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Subjects With Relapsed/Refractory Multiple Myeloma",
"has_exemption": false,
"start_date": "2026-02-18",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "C4 Therapeutics, Inc.",
"sponsor_slug": "c4-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07464886",
"publication_url": "https://clinicaltrials.gov/study/NCT07464886",
"title": "Prefrontal Glutamatergic Modulation by N-acetylcysteine and Mindfulness-based Cognitive Therapy for Mild Depression in Youth",
"has_exemption": false,
"start_date": "2026-02-26",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Cincinnati",
"sponsor_slug": "university-of-cincinnati",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07158242",
"publication_url": "https://clinicaltrials.gov/study/NCT07158242",
"title": "A Phase III Randomized Double-Blind Multi-Center Treat-Through Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Children Aged 2 - 17 Years With Moderately to Severely Active Ulcerative Colitis",
"has_exemption": false,
"start_date": "2026-04-15",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Hoffmann-La Roche",
"sponsor_slug": "hoffmann-la-roche",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07346144",
"publication_url": "https://clinicaltrials.gov/study/NCT07346144",
"title": "A Phase I/II Study of an AAV-1 Mediated Dual-Payload Gene Therapy in Patients With High Grade Glioma",
"has_exemption": false,
"start_date": "2026-04-21",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Trogenix ltd",
"sponsor_slug": "trogenix-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07089901",
"publication_url": "https://clinicaltrials.gov/study/NCT07089901",
"title": "Project DEDUCE: Digital Envirotyping to Develop Understanding of Cigarette Smoking and the Environment",
"has_exemption": false,
"start_date": "2026-05-06",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Duke University",
"sponsor_slug": "duke-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07566156",
"publication_url": "https://clinicaltrials.gov/study/NCT07566156",
"title": "A PHASE 3, OPEN-LABEL, RANDOMIZED STUDY TO EVALUATE ENFORTUMAB VEDOTIN IN COMBINATION WITH PEMBROLIZUMAB IN ADULT PARTICIPANTS WITH MUSCLE-INVASIVE BLADDER CANCER WHO ARE INELIGIBLE FOR OR HAVE ELECTED NOT TO UNDERGO CYSTECTOMY",
"has_exemption": false,
"start_date": "2026-05-11",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Astellas Pharma Global Development, Inc.",
"sponsor_slug": "astellas-pharma-global-development-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07605962",
"publication_url": "https://clinicaltrials.gov/study/NCT07605962",
"title": "A Phase I/II Open-Label, Dose Escalation, Dose Optimization, and Cohort Expansion Trial to Investigate the Safety, Pharmacokinetics and Pharmacodynamics of UI-102, a Novel Cholesteryl Pullulan (CHP) Nanoparticle-formulated TLR7/8 Agonist in Patients With Selected Locally Advanced and/or Metastatic Solid Tumors",
"has_exemption": false,
"start_date": "2026-05-20",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "United Immunity, co., Ltd.",
"sponsor_slug": "united-immunity-co-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07262060",
"publication_url": "https://clinicaltrials.gov/study/NCT07262060",
"title": "Optimizing Caffeine Therapy for Hypoxia in Preterm Neonates: A Randomized Trial Assessing Efficacy, Acute Kidney and Brain Injury, Safety, and Pharmacokinetics",
"has_exemption": false,
"start_date": "2026-05-28",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Wisconsin, Madison",
"sponsor_slug": "university-of-wisconsin-madison",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07606274",
"publication_url": "https://clinicaltrials.gov/study/NCT07606274",
"title": "A Phase 1/2, First-in-Human, Open-Label, Multicenter, Single-Dose Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of NVC-001, a Novel Adeno-Associated Virus (Serotype 9) Vector Expressing a Dominant Negative SUN1 Transgene, in Patients With LMNA-Related Dilated Cardiomyopathy (SUNBEAM-LMNA)",
"has_exemption": false,
"start_date": "2026-06-16",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Nuevocor Pte. Ltd.",
"sponsor_slug": "nuevocor-pte-ltd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07668336",
"publication_url": "https://clinicaltrials.gov/study/NCT07668336",
"title": "A Phase 3, Randomized, Open-Label Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Once-Daily Oral Orforglipron Compared With Once-Weekly Dulaglutide in Pediatric Participants 10 to Less Than 18 Years of Age With Type 2 Diabetes",
"has_exemption": false,
"start_date": "2026-07-08",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Eli Lilly and Company",
"sponsor_slug": "eli-lilly-and-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07688551",
"publication_url": "https://clinicaltrials.gov/study/NCT07688551",
"title": "Transcranial Direct Current Stimulation to Treat Aphasia: A Superiority Study",
"has_exemption": false,
"start_date": "2026-07-14",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "University of South Carolina",
"sponsor_slug": "university-of-south-carolina",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07448974",
"publication_url": "https://clinicaltrials.gov/study/NCT07448974",
"title": "Vitamin D and Type 2 Diabetes, Treat-To-Target",
"has_exemption": false,
"start_date": "2026-08-04",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Tufts Medical Center",
"sponsor_slug": "tufts-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07639086",
"publication_url": "https://clinicaltrials.gov/study/NCT07639086",
"title": "Sacituzumab Tirumotecan in Patients With Neuroendocrine Prostate Cancer After Progression on Prior Chemotherapy",
"has_exemption": false,
"start_date": "2026-08-31",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Virginia Commonwealth University",
"sponsor_slug": "virginia-commonwealth-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07187466",
"publication_url": "https://clinicaltrials.gov/study/NCT07187466",
"title": "Sequential Multiple Assignment Randomized Trial to Treat Urinary Symptoms in Parkinson Disease",
"has_exemption": false,
"start_date": "2026-10-21",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07859215",
"publication_url": "https://clinicaltrials.gov/study/NCT07859215",
"title": "Randomized, Open-Label, Phase 3 Study of Rinatabart Sesutecan (Rina-S) Plus Standard of Care Versus Standard of Care as Maintenance Treatment in Participants With Ovarian Cancer Following First-Line (1L) Platinum-Based Chemotherapy",
"has_exemption": false,
"start_date": "2026-11-30",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Genmab",
"sponsor_slug": "genmab",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07281027",
"publication_url": "https://clinicaltrials.gov/study/NCT07281027",
"title": "Comparing the Effects of Anakinra and Tocilizumab on Outcomes in Patients With New-Onset Refractory Status Epilepticus",
"has_exemption": false,
"start_date": "2026-12-01",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Yale University",
"sponsor_slug": "yale-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07821684",
"publication_url": "https://clinicaltrials.gov/study/NCT07821684",
"title": "A Phase 3 Open Label Randomized Study of Telisotuzumab Adizutecan Compared to Standard of Care in Subjects With Previously Treated, EGFR Wildtype, Locally Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer Expressing c-Met Protein Level Above a Defined Cutoff",
"has_exemption": false,
"start_date": "2027-01-06",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "AbbVie",
"sponsor_slug": "abbvie",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07751744",
"publication_url": "https://clinicaltrials.gov/study/NCT07751744",
"title": "A Phase 1/2, Multicenter, Open-Label, Dose-Escalation/Expansion Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of Orally Administered JBI-778 in Patients With Brain Metastasis, Leptomeningeal Disease, or High Grade Recurrent Glioma",
"has_exemption": false,
"start_date": "2028-04-01",
"completion_date": "2030-03-31",
"has_results": false,
"results_due": false,
"sponsor_name": "Jubilant Therapeutics Inc.",
"sponsor_slug": "jubilant-therapeutics-inc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04042402",
"publication_url": "https://clinicaltrials.gov/study/NCT04042402",
"title": "An Open-Label Roll-Over Study to Evaluate the Long-Term Safety and Efficacy of DCR-PHXC Solution for Injection (Subcutaneous Use) in Patients With Primary Hyperoxaluria",
"has_exemption": false,
"start_date": "2019-07-09",
"completion_date": "2030-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Dicerna Pharmaceuticals, Inc., a Novo Nordisk company",
"sponsor_slug": "dicerna-pharmaceuticals-inc-a-novo-nordisk-company",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT04675398",
"publication_url": "https://clinicaltrials.gov/study/NCT04675398",
"title": "Adaptive Cortical and Subcortical Brain Stimulation to Improve Motor Behaviors and Gait in Parkinson's Disease",
"has_exemption": false,
"start_date": "2021-06-15",
"completion_date": "2030-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Doris Wang, MD, PhD",
"sponsor_slug": "doris-wang-md-phd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05623306",
"publication_url": "https://clinicaltrials.gov/study/NCT05623306",
"title": "A Double-Blinded, Randomized, Crossover Trial of Stereoencephalography- Guided Multi-Lead Deep Brain Stimulation for Treatment-Refractory Obsessive-Compulsive Disorder (SEEG-Guided DBS for OCD)",
"has_exemption": false,
"start_date": "2023-04-13",
"completion_date": "2030-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Casey H. Halpern, M.D.",
"sponsor_slug": "casey-h-halpern-md",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07112287",
"publication_url": "https://clinicaltrials.gov/study/NCT07112287",
"title": "MyeloGen: Germline Testing for Predisposition to Myeloid Malignancies",
"has_exemption": false,
"start_date": "2025-11-10",
"completion_date": "2030-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Christopher Reilly",
"sponsor_slug": "christopher-reilly",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07424508",
"publication_url": "https://clinicaltrials.gov/study/NCT07424508",
"title": "Movement State-Dependent Adaptive Deep Brain Stimulation for Parkinson's Disease",
"has_exemption": false,
"start_date": "2026-02-04",
"completion_date": "2030-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Doris Wang, MD, PhD",
"sponsor_slug": "doris-wang-md-phd",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07489976",
"publication_url": "https://clinicaltrials.gov/study/NCT07489976",
"title": "Leveraging Immunotherapy For Tumor Downstaging to Milan Criteria in Patients With Hepatocellular Carcinoma",
"has_exemption": false,
"start_date": "2026-04-01",
"completion_date": "2030-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Ju Dong Yang",
"sponsor_slug": "ju-dong-yang",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07783581",
"publication_url": "https://clinicaltrials.gov/study/NCT07783581",
"title": "Phase II: Randomized Neoadjuvant Treatment of Oral Cavity Cancer With Spatially Fractionated Proton Radiotherapy and Immunotherapy (OSPRI)",
"has_exemption": false,
"start_date": "2026-09-07",
"completion_date": "2030-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Mayo Clinic",
"sponsor_slug": "mayo-clinic",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07755059",
"publication_url": "https://clinicaltrials.gov/study/NCT07755059",
"title": "A Prospective, Multi-Center, Single-Arm Clinical Study of Proximal Splenic Artery Embolization (PSAE) for the Treatment of Refractory Ascites in Decompensated Cirrhosis",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2030-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07029776",
"publication_url": "https://clinicaltrials.gov/study/NCT07029776",
"title": "A Phase 2 Study Exploring the Use of Bispecific Antibodies to Improve Progression Free Survival in Patients With High-Risk Newly Diagnosed Multiple Myeloma (MMulti-Immune HR)",
"has_exemption": false,
"start_date": "2027-03-01",
"completion_date": "2030-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "University of Arkansas",
"sponsor_slug": "university-of-arkansas",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07809854",
"publication_url": "https://clinicaltrials.gov/study/NCT07809854",
"title": "Evaluating an Innovative Tobacco Treatment Approach for Veterans in Substance Use Disorder Treatment",
"has_exemption": false,
"start_date": "2027-04-01",
"completion_date": "2030-04-01",
"has_results": false,
"results_due": false,
"sponsor_name": "VA Office of Research and Development",
"sponsor_slug": "va-office-of-research-and-development",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05972629",
"publication_url": "https://clinicaltrials.gov/study/NCT05972629",
"title": "A Phase 1/Phase 2, Open-label, Dose-escalation, and Dose Expansion Study to Evaluate the Safety, Tolerability, and Efficacy of SAR444836, an Adeno-associated Viral Vector-mediated Gene Transfer of Human Phenylalanine Hydroxylase, in Adult Participants With Phenylketonuria",
"has_exemption": false,
"start_date": "2023-08-07",
"completion_date": "2030-04-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Sanofi",
"sponsor_slug": "sanofi",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07326709",
"publication_url": "https://clinicaltrials.gov/study/NCT07326709",
"title": "A Randomized, Placebo-controlled, Double-blind Phase 3 Study to Evaluate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease",
"has_exemption": false,
"start_date": "2026-03-24",
"completion_date": "2030-04-02",
"has_results": false,
"results_due": false,
"sponsor_name": "Novartis Pharmaceuticals",
"sponsor_slug": "novartis-pharmaceuticals",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07750158",
"publication_url": "https://clinicaltrials.gov/study/NCT07750158",
"title": "Randomized Phase 3 Study of Zanzalintinib ± Subcutaneous Pembrolizumab and Berahyaluronidase Alfa (MK-3475A) Versus Placebo in Participants With Colorectal Cancer With Stage II/III Molecular Residual Disease Following Definitive Therapy",
"has_exemption": false,
"start_date": "2026-08-25",
"completion_date": "2030-04-05",
"has_results": false,
"results_due": false,
"sponsor_name": "Exelixis",
"sponsor_slug": "exelixis",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03718403",
"publication_url": "https://clinicaltrials.gov/study/NCT03718403",
"title": "Effect of Theophylline in Pseudohypoparathyroidism",
"has_exemption": false,
"start_date": "2019-11-11",
"completion_date": "2030-04-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Massachusetts General Hospital",
"sponsor_slug": "massachusetts-general-hospital",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07754578",
"publication_url": "https://clinicaltrials.gov/study/NCT07754578",
"title": "High-Dose Nicotine Replacement Therapy for Quitting Cigarettes and E-cigarettes",
"has_exemption": false,
"start_date": "2026-11-01",
"completion_date": "2030-04-10",
"has_results": false,
"results_due": false,
"sponsor_name": "Medical University of South Carolina",
"sponsor_slug": "medical-university-of-south-carolina",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT05582993",
"publication_url": "https://clinicaltrials.gov/study/NCT05582993",
"title": "A Phase 3, Prospective, Open-label, Uncontrolled, Multicenter Study on Efficacy and Safety of Prophylaxis With Vonicog Alfa (rVWF) in Children Diagnosed With Severe Von Willebrand Disease",
"has_exemption": false,
"start_date": "2024-11-06",
"completion_date": "2030-04-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06632977",
"publication_url": "https://clinicaltrials.gov/study/NCT06632977",
"title": "PREcision DIagnostics in Prostate Cancer Treatment (PREDICT)",
"has_exemption": false,
"start_date": "2025-02-06",
"completion_date": "2030-04-11",
"has_results": false,
"results_due": false,
"sponsor_name": "Alliance for Clinical Trials in Oncology",
"sponsor_slug": "alliance-for-clinical-trials-in-oncology",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT03011814",
"publication_url": "https://clinicaltrials.gov/study/NCT03011814",
"title": "A Phase 1/2 Trial of Durvalumab (MEDI4736) When Given as a Single Agent or in Combination With Lenalidomide in Patients With Relapsed/ Refractory Peripheral T-cell Lymphoma, Including Cutaneous T-cell Lymphoma",
"has_exemption": false,
"start_date": "2017-03-08",
"completion_date": "2030-04-14",
"has_results": false,
"results_due": false,
"sponsor_name": "City of Hope Medical Center",
"sponsor_slug": "city-of-hope-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07061574",
"publication_url": "https://clinicaltrials.gov/study/NCT07061574",
"title": "A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes",
"has_exemption": false,
"start_date": "2026-03-10",
"completion_date": "2030-04-15",
"has_results": false,
"results_due": false,
"sponsor_name": "City of Hope Medical Center",
"sponsor_slug": "city-of-hope-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06397703",
"publication_url": "https://clinicaltrials.gov/study/NCT06397703",
"title": "A Phase II Prospective 2-Arm Cohort Interventional Trial Utilizing Ultra-Hypofractionated SBRT With or Without Short Course Androgen Deprivation Therapy For Unfavorable Intermediate Risk Prostate Cancer",
"has_exemption": false,
"start_date": "2024-04-16",
"completion_date": "2030-04-16",
"has_results": false,
"results_due": false,
"sponsor_name": "NYU Langone Health",
"sponsor_slug": "nyu-langone-health",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06129864",
"publication_url": "https://clinicaltrials.gov/study/NCT06129864",
"title": "A Phase III, Randomized, Open-Label, Multi-Center, Global Study of Volrustomig (MEDI5752) as Sequential Therapy Versus Observation in Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma, Who Have Not Progressed Following Definitive Concurrent Chemoradiotherapy (eVOLVE-HNSCC)",
"has_exemption": false,
"start_date": "2023-12-14",
"completion_date": "2030-04-17",
"has_results": false,
"results_due": false,
"sponsor_name": "AstraZeneca",
"sponsor_slug": "astrazeneca",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07843940",
"publication_url": "https://clinicaltrials.gov/study/NCT07843940",
"title": "A Phase Ib/II, Open-label, Safety and Tolerability Trial of Intravenous Obrixtamig in Combination With Pumitamig and Standard of Care (Carboplatin, Etoposide) in Patients With Extensive-stage Small Cell Lung Carcinoma",
"has_exemption": false,
"start_date": "2026-10-01",
"completion_date": "2030-04-17",
"has_results": false,
"results_due": false,
"sponsor_name": "Boehringer Ingelheim",
"sponsor_slug": "boehringer-ingelheim",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06686394",
"publication_url": "https://clinicaltrials.gov/study/NCT06686394",
"title": "HERTHENA-Breast-01: A Phase 1b/2, Multicenter, Open-label, Dose-Finding Study to Evaluate the Safety and Antitumor Activity of Patritumab Deruxtecan in Participants With HER2 Positive Unresectable Locally Advanced Breast Cancer or Metastatic Breast Cancer",
"has_exemption": false,
"start_date": "2025-02-26",
"completion_date": "2030-04-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Merck Sharp & Dohme LLC",
"sponsor_slug": "merck-sharp-dohme-llc",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07871721",
"publication_url": "https://clinicaltrials.gov/study/NCT07871721",
"title": "A Multicenter, Randomized, Double-Blind, and Placebo-Controlled Phase 3b Study to Evaluate the Efficacy and Safety of Zasocitinib (TAK-279) on Clinical Response and Inhibition of Radiographic Progression in Participants With Active Psoriatic Arthritis",
"has_exemption": false,
"start_date": "2027-01-11",
"completion_date": "2030-04-18",
"has_results": false,
"results_due": false,
"sponsor_name": "Takeda",
"sponsor_slug": "takeda",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06117774",
"publication_url": "https://clinicaltrials.gov/study/NCT06117774",
"title": "A Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter Study of Tarlatamab Therapy in Subjects With Limited-Stage Small-Cell Lung Cancer (LS-SCLC) Who Have Not Progressed Following Concurrent Chemoradiation Therapy",
"has_exemption": false,
"start_date": "2024-02-20",
"completion_date": "2030-04-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Amgen",
"sponsor_slug": "amgen",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07821398",
"publication_url": "https://clinicaltrials.gov/study/NCT07821398",
"title": "Harmonized Hyperpolarized 129Xe MRI for Noninvasive Assessment of Pulmonary Hypertension in Interstitial Lung Disease and Systemic Sclerosis (ILD-PH/SSc)",
"has_exemption": false,
"start_date": "2026-11-01",
"completion_date": "2030-04-20",
"has_results": false,
"results_due": false,
"sponsor_name": "Bastiaan Driehuys",
"sponsor_slug": "bastiaan-driehuys",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT07578077",
"publication_url": "https://clinicaltrials.gov/study/NCT07578077",
"title": "A Phase 1/2 Study of the CELMoD Agent Golcadomide in Combination With Rituximab in Patients With Relapsed or Refractory Mantle Cell Lymphoma",
"has_exemption": false,
"start_date": "2026-12-21",
"completion_date": "2030-04-21",
"has_results": false,
"results_due": false,
"sponsor_name": "City of Hope Medical Center",
"sponsor_slug": "city-of-hope-medical-center",
"status": "ongoing",
"is_pact": false,
"days_late": null
},
{
"registry_id": "NCT06835504",
"publication_url": "https://clinicaltrials.gov/study/NCT06835504",
"title": "Efficacy of Intravenous Sub-Dissociative Ketamine Versus Intravenous Morphine in Children With Acute Pain",
"has_exemption": false,
"start_date": "2026-10-17",
"completion_date": "2030-04-23",
"has_results": false,
"results_due": false,
"sponsor_name": "Columbia University",
"sponsor_slug": "columbia-university",
"status": "ongoing",
"is_pact": false,
"days_late": null
}
]
}