All individual trials at Massachusetts General Hospital
Trials reported
158 out of 210
Percent reported
75.2%
US Govt could have imposed fines of at least
$415,489,066
Fines claimed by US Govt
$0
Showing 1 to 100 of 395 entries
Status | Sponsor | Trial ID | Title | Completion date | Days overdue |
---|---|---|---|---|---|
reported | Massachusetts General Hospital | NCT01783574 | Collaborative Study: Testosterone Antidepressant Augmentation in Women [pACT] | 2017-01-27 | |
reported-late | Massachusetts General Hospital | NCT01616160 | An Open-label Study to Identify Molecular Markers of Steroid Resistance in Nasal Polyposis Before and Following Treatment With Mometasone Furoate (MFNS) 2 Sprays/Nostril (100 mcg/Nostril) Twice Daily for 4 Weeks. [pACT] | 2017-01-31 | 48 |
reported | Massachusetts General Hospital | NCT01588821 | Phase II Trial of Cabozantinib (XL184) in Patients With Advanced Solid (Non-breast, Non-prostate) Malignancies and Bony Metastases [pACT] | 2017-01-31 | |
reported | Massachusetts General Hospital | NCT01920555 | Double-Blind, Placebo-Controlled Trial of Ketamine Therapy in Treatment-Resistant Depression (TRD) [pACT] | 2017-01-31 | |
reported | Massachusetts General Hospital | NCT02669043 | Physiological and Cognitive Biomarkers for Ketamine's Antidepressant Effects [pACT] | 2017-02-28 | |
reported | Massachusetts General Hospital | NCT02448537 | A Phase II Multi-Strata Study of PM01183 as a Single Agent or in Combination With Conventional Chemotherapy in Metastatic and/or Unresectable Sarcomas [pACT] | 2017-02-28 | |
reported | Massachusetts General Hospital | NCT01853280 | L-methylfolate Supplementation to OROS-Methylphenidate Pharmacotherapy in ADHD Adults: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial [pACT] | 2017-02-28 | |
reported | Massachusetts General Hospital | NCT02164981 | A Randomized Double-Blind, Placebo-Controlled, Proof of Concept Study of Intravenous Sodium Nitroprusside in Adults With Symptomatic Schizophrenia [pACT] | 2017-03-31 | |
reported | Massachusetts General Hospital | NCT01591733 | Phase II Study of Preoperative FOLFIRINOX Followed by Accelerated Short Course Radiation Therapy for Borderline-Resectable Pancreatic Cancer [pACT] | 2017-03-31 | |
reported | Massachusetts General Hospital | NCT01074177 | Understanding Mechanisms of Acquired Resistance to BIBW2992 [pACT] | 2017-03-31 | |
reported | Massachusetts General Hospital | NCT01854034 | Phase II Study of AUY922 in NSCLC Patients With Exon 20 Insertion Mutations in EGFR [pACT] | 2017-03-31 | |
reported | Massachusetts General Hospital | NCT01405456 | Randomized Placebo-controlled Trial to Investigate the Effects of Eplerenone in Patients With HIV-associated Abdominal Fat Accumulation [pACT] | 2017-05-03 | |
reported-late | Massachusetts General Hospital | NCT03807089 | Adenoma Detection Rate With a New Pediatric Colonoscope With a Short Turn Radius (Pentax Retroview) Compared With a Standard Pentax Pediatric Colonoscope [pACT] | 2017-05-11 | 383 |
reported | Massachusetts General Hospital | NCT02516150 | Effect of Ethanol Intoxication on the Anti-hypoglycemic Action of Glucagon [pACT] | 2017-05-31 | |
reported | Massachusetts General Hospital | NCT02969863 | The Monitoring Study: Evaluating the Effect of Remote Monitoring For Hypoglycemia on Bionic Pancreas Safety and Efficacy | 2017-06-01 | |
reported | Massachusetts General Hospital | NCT01752400 | A Phase II Open-Label Trial of AUY922, an HSP90 Inhibitor, in Patients With ALK-Rearranged Advanced Non-Small Cell Lung Cancer and Acquired Resistance to Prior ALK Tyrosine Kinase Inhibition [pACT] | 2017-06-30 | |
reported-late | Massachusetts General Hospital | NCT01408563 | A Phase II Study of Reduced Intensity Double Umbilical Cord Blood Transplantation Using Fludarabine, Melphalan, and Low Dose Total Body Radiation [pACT] | 2017-06-30 | 76 |
reported | Massachusetts General Hospital | NCT01750879 | Clinical Desensitization and Tolerance Following Peanut Oral Immunotherapy and Subsequent Allergen Avoidance [pACT] | 2017-07-11 | |
reported | Massachusetts General Hospital | NCT02410252 | Use Feasibility of the iThermonitor in Pediatric Patients on Myelosuppresive Therapies for Acute Leukemia and Other Childhood Cancers [pACT] | 2017-07-31 | |
reported | Massachusetts General Hospital | NCT01667029 | A Single-center, Randomized, Double-blind Clinical Study to Evaluate the Effect of Sulfasalazine on Painful Neuropathy [pACT] | 2017-08-10 | |
reported | Massachusetts General Hospital | NCT02959996 | Liposomal Bupivacaine at Cesarean Delivery to Decrease Post-operative Pain | 2017-09-25 | |
reported-late | Massachusetts General Hospital | NCT02503735 | Effect of Ledipasvir and Sofosbuvir on Proteinuria and Estimated Glomerular Filtration Rate in Patients With Early Stage (1-3) Hepatitis C Associated Chronic Kidney Disease [pACT] | 2017-09-30 | 417 |
reported-late | Massachusetts General Hospital | NCT02961946 | Effects of Sublingual and Transdermal Administration of Nitroglycerin for Coronary CT Angiography on Image Quality | 2017-10-31 | 276 |
reported | Massachusetts General Hospital | NCT02671266 | Effect of Intranasal Oxytocin on Social Cognition [pACT] | 2017-10-31 | |
reported | Massachusetts General Hospital | NCT02560025 | A Phase II Study of the Aurora A Kinase Inhibitor Alisertib in Combination With 7+3 Induction Chemotherapy in Patients With High-risk Acute Myeloid Leukemia [pACT] | 2017-10-31 | |
reported | Massachusetts General Hospital | NCT02558790 | L-Threonic Acid Magnesium Salt (L-TAMS) in ADHD: An Open-label Pilot Study of Cognitive and Functional Effects [pACT] | 2017-10-31 | |
reported-late | Massachusetts General Hospital | NCT01914939 | A Randomized, Controlled Trial of Intranasal Oxytocin as an Adjunct to Behavioral Therapy for Autism Spectrum Disorder [pACT] | 2017-11-30 | 1108 |
reported | Massachusetts General Hospital | NCT01399827 | Omega-3 Fatty Acid Supplementation to ADHD Pharmacotherapy in ADHD Adults With DESR Traits: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial [pACT] | 2017-11-30 | |
reported | Massachusetts General Hospital | NCT02544607 | Baseline Insular Dysfunction as a Predictor of Ketamine's Antidepressant Effects in Anxious Depression [pACT] | 2017-12-29 | |
reported | Massachusetts General Hospital | NCT02509065 | The Set-Point Study: Evaluating Effects of Changing Glucose Target on Bionic Pancreas Performance [pACT] | 2017-12-31 | |
reported | Massachusetts General Hospital | NCT00567359 | A Phase II Trial of Adjuvant Erlotinib in Patients With Resected, Early Stage Non-Small Cell Lung Cancer (NSCLC) With Confirmed Mutations in the Epidermal Growth Factor Receptor (EGFR) [pACT] | 2017-12-31 | |
reported | Massachusetts General Hospital | NCT02966275 | Closed-Loop Glucagon Administration For The Automated Treatment Of Post-Bariatric Hypoglycemia [pACT] | 2017-12-31 | |
overdue | Massachusetts General Hospital | NCT03036085 | Liposomal Bupivacaine Versus Bupivacaine for Postoperative Analgesia Following Video-assisted Thoracoscopic Surgery. | 2017-12-31 | 1866 |
reported-late | Massachusetts General Hospital | NCT02900092 | Treatment-Resistant Depression Augmentation Therapy With An Analog of the Neuroactive Steroid Allopregnanolone: A Pilot Study [pACT] | 2018-01-12 | 3 |
reported | Massachusetts General Hospital | NCT01485393 | Pilot Study Comparing the Use of Dexmedetomidine and Zolpidem to Induce Natural Sleep [pACT] | 2018-01-29 | |
reported | Massachusetts General Hospital | NCT02096952 | Open-Label Treatment Trial to Assess the Short-Term Tolerability, Safety, and Efficacy of Methylphenidate Hydrochloride Extended-Release Liquid Formulation in High-Functioning Autism Spectrum Disorder Adults With Attention-Deficit/Hyperactivity Disorder [pACT] | 2018-01-31 | |
reported-late | Massachusetts General Hospital | NCT02428855 | Phase II Trial of Dasatinib in Patients With Isocitrate Dehydrogenase (IDH)-Mutant Advanced Intrahepatic Cholangiocarcinoma [pACT] | 2018-02-28 | 508 |
reported-late | Massachusetts General Hospital | NCT03217175 | Efficacy of Glucagon In the Prevention of Hypoglycemia During Mild Exercise | 2018-03-09 | 156 |
reported-late | Massachusetts General Hospital | NCT03552523 | The Set-Point Study for Type 2 Diabetes: Evaluating the Safety and Efficacy of an Insulin Only Bionic Pancreas System in Patients With Type 2 Diabetes | 2018-03-29 | 125 |
reported-late | Massachusetts General Hospital | NCT01652079 | A Phase II, 2-stage Trial of CRLX101 in Combination With Bevacizumab in Recurrent Platinum-Resistant Ovarian, Tubal and Peritoneal Cancer [pACT] | 2018-03-31 | 1354 |
reported-late | Massachusetts General Hospital | NCT02150863 | Treatment of Field Cancerization for Reduction in Tumor Burden - A Prospective Study [pACT] | 2018-04-30 | 164 |
reported | Massachusetts General Hospital | NCT02290106 | Effects of Pitavastatin on Insulin Sensitivity and Liver Fat [pACT] | 2018-04-30 | |
reported-late | Massachusetts General Hospital | NCT01972074 | Behavioral and Neural Response to Memantine in Adolescents With Autism Spectrum Disorder [pACT] | 2018-05-07 | 86 |
reported | Massachusetts General Hospital | NCT03054506 | A Randomized, Single Center, Double-blind, Parallel-group, Placebo-controlled Study Assessing the Effect of CSP01 on Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation | 2018-05-10 | |
reported | Massachusetts General Hospital | NCT02051452 | Reversal of General Anesthesia With Intravenous Methylphenidate [pACT] | 2018-05-31 | |
reported-late | Massachusetts General Hospital | NCT02701257 | The iLet Introduction Study: A Feasibility Study of the iLet, a Fully Integrated Bihormonal Bionic Pancreas [pACT] | 2018-05-31 | 66 |
reported | Massachusetts General Hospital | NCT02530385 | Placebo Controlled Study of Fecal Microbiota Transplant (FMT) to Impact Body Weight and Glycemic Control in Adults Using a Frozen Encapsulated Inoculum [pACT] | 2018-06-27 | |
reported-late | Massachusetts General Hospital | NCT01813734 | A Phase II, Open-Label Study of Ponatinib, A Multi-Targeted Oral Tyrosine Kinase Inhibitor, in Advanced Non-Small Cell Lung Cancer Harboring RET Translocations [pACT] | 2018-06-30 | 120 |
reported-late | Massachusetts General Hospital | NCT02818569 | Repurposing Dexmedetomidine as an Orally Administered Sleep Therapeutic [pACT] | 2018-06-30 | 46 |
reported-late | Massachusetts General Hospital | NCT01780454 | Renal Allograft Tolerance Through Mixed Chimerism [pACT] | 2018-06-30 | 429 |
overdue-cancelled | Massachusetts General Hospital | NCT02458976 | Pulsed-dye Laser Treatment Prior to Surgical Excision [pACT] | 2018-06-30 | 1685 |
reported-late | Massachusetts General Hospital | NCT02553915 | Omega-3 Fatty Acids for MDD With High Inflammation: A Personalized Approach [pACT] | 2018-07-13 | 41 |
reported-late | Massachusetts General Hospital | NCT01775501 | Phase II Trial of Sorafenib in Combination With Modified FOLFOX in Patients With Advanced Hepatocellular Carcinoma [pACT] | 2018-07-31 | 211 |
reported-late | Massachusetts General Hospital | NCT02536105 | Pharmacokinetic Pharmacodynamic Studies of Methylphenidate Extended Release Products in Pediatric Attention Deficit Hyperactivity Disorder [pACT] | 2018-07-31 | 35 |
reported-late | Massachusetts General Hospital | NCT01821729 | Phase II Feasibility Study of FOLFIRINOX-Losartan Followed by Accelerated Short Course Radiation Therapy With Capecitabine for Locally Advanced Pancreatic Cancer [pACT] | 2018-07-31 | 27 |
reported-late | Massachusetts General Hospital | NCT03503578 | Electroencephalogram Studies of Induction and Recovery From Sevoflurane-Induced General Anesthesia | 2018-08-01 | 1 |
reported-late | Massachusetts General Hospital | NCT02969876 | Pattern Separation, Brain Derived Neurotrophic Factors, and Mechanisms of Vortioxetine | 2018-08-06 | 48 |
reported-late | Massachusetts General Hospital | NCT03342560 | Beyond Confounders: Addressing Source of Measurement Variability and Error in Shear Wave Elastography | 2018-08-14 | 13 |
overdue | Massachusetts General Hospital | NCT04467164 | Vagus Nerve Stimulation: Integration of Behavior and Cardiac Modulation [pACT] | 2018-09-15 | 1608 |
reported | Massachusetts General Hospital | NCT02357290 | Open-Label Study of N-Acetylcysteine in Children and Adolescents Ages 5-17 With Bipolar I, Bipolar II, and Bipolar Spectrum Disorder [pACT] | 2018-09-24 | |
reported | Massachusetts General Hospital | NCT03380845 | Comparison of Fractional Erbium-Doped 1,550-nm Laser and a Bipolar Fractional Radiofrequency Microneedle Device for the Treatment of Atrophic Acne Scars in Ethnic Skin: A Randomized Split-Face Controlled Pilot Study | 2018-10-30 | |
reported | Massachusetts General Hospital | NCT01724489 | Skeletal Physiology Dysregulation in Obesity: The Role of Growth Hormone [pACT] | 2018-11-15 | |
reported | Massachusetts General Hospital | NCT04112069 | The Insulin-Only Bionic Pancreas Bridging Study- Pediatric Transitional Study | 2018-11-19 | |
reported | Massachusetts General Hospital | NCT03565666 | The Insulin-Only Bionic Pancreas Bridging Study | 2018-11-19 | |
reported-late | Massachusetts General Hospital | NCT02959307 | Transcranial Continuous and Pulse Near-Infrared Light in Depression: a Placebo-Controlled Study (ELATED-3). [pACT] | 2018-11-30 | 199 |
reported | Massachusetts General Hospital | NCT03096314 | Vitamin D to Improve Outcomes by Leveraging Early Treatment | 2018-12-11 | |
reported-late | Massachusetts General Hospital | NCT02985749 | A Pilot Study of Oxytocin for the Treatment of Social Impairment in Individuals With High Functioning Autism Spectrum Disorder | 2019-01-09 | 1252 |
reported | Massachusetts General Hospital | NCT02196831 | Tesamorelin Effects on Liver Fat and Histology in HIV: A Collaborative UO1 Grant [pACT] | 2019-01-16 | |
reported-late | Massachusetts General Hospital | NCT03174158 | A Text Messaging Intervention for Smoking Cessation Among Community Health Center Patients | 2019-01-17 | 5 |
reported-late | Massachusetts General Hospital | NCT03553758 | Electroencephalogram Studies of Induction and Recovery From Ketamine-Induced General Anesthesia | 2019-02-01 | 159 |
reported | Massachusetts General Hospital | NCT02394548 | A Phase I Trial Of Intensity-Modulated Radiation Therapy (IMRT) Using A Contralateral Esophagus Sparing Technique (CEST) In Locally Advanced Non-Small Cell Lung Cancer (NSCLC) And Limited-Stage Small Cell Lung Cancer (LS-SCLC). [pACT] | 2019-02-28 | |
reported-late | Massachusetts General Hospital | NCT02003625 | Non-steroidal Anti-inflammatory Drugs (Meloxicam) to Mobilize Hematopoietic Stem Cells: A Phase II Randomized Trial [pACT] | 2019-02-28 | 62 |
reported-late | Massachusetts General Hospital | NCT02431572 | A Pilot Study to Evaluate PBR PET in Brain Tumor Patients Treated With Chemoradiation or Immunotherapy [pACT] | 2019-02-28 | 52 |
reported | Massachusetts General Hospital | NCT02694757 | Pilot Study to Evaluate the Efficacy of Ostom-i Alert System at Decreasing Dehydration Related Complications in Patients With New Ileostomies | 2019-03-04 | |
reported-late | Massachusetts General Hospital | NCT03102710 | Neuromodulation of Placebo and Nocebo Effects [pACT] | 2019-03-31 | 43 |
reported-late | Massachusetts General Hospital | NCT01301183 | Effects of Anorexia Nervosa on Peak Bone Mass [pACT] | 2019-03-31 | 424 |
reported-late | Massachusetts General Hospital | NCT03149991 | A Double-Blind, Placebo-Controlled Study of Brexpiprazole Plus Ketamine in Treatment-Resistant Depression (TRD) | 2019-03-31 | 50 |
reported | Massachusetts General Hospital | NCT01396486 | A Randomized Controlled Trial of Inositol and Omega-3 Fatty Acids in Pediatric Mania [pACT] | 2019-04-11 | |
reported-late | Massachusetts General Hospital | NCT02076152 | A Study to Evaluate Vascular Normalization in Patients With Recurrent Glioblastoma Treated With Bevacizumab Using FMISO PET and Vascular MRI [pACT] | 2019-04-30 | 365 |
reported-late | Massachusetts General Hospital | NCT00592501 | A Phase II Study of Proton Radiotherapy With Chemotherapy for Nasopharyngeal Carcinoma [pACT] | 2019-04-30 | 398 |
reported-late | Massachusetts General Hospital | NCT01987830 | A Study to Evaluate Vascular Normalization in Patients With Recurrent Glioblastoma Treated With Bevacizumab Using [11C]Temozolomide PET and Vascular MRI [pACT] | 2019-04-30 | 110 |
reported-late | Massachusetts General Hospital | NCT03412604 | Effect of Modulating Gamma Oscillations by Transcranial Alternating Current Stimulation on Brain Structure and Function in Humans | 2019-05-07 | 64 |
reported-late | Massachusetts General Hospital | NCT03290326 | Feasibility and Safety of a High-Frequency Transcranial Alternating Current Stimulation Intervention for Amyloid-β Reduction in Alzheimer's Disease | 2019-05-14 | 67 |
reported-late | Massachusetts General Hospital | NCT02831257 | A Single Arm Phase 2 Study of the Dual mTORC1/mTORC2 Inhibitor AZD2014 Provided on an Intermittent Schedule for Neurofibromatosis 2 Patients With Progressive or Symptomatic Meningiomas [pACT] | 2019-05-31 | 151 |
reported | Massachusetts General Hospital | NCT01406444 | IGF-1 and Bone Loss in Women With Anorexia Nervosa [pACT] | 2019-05-31 | |
reported | Massachusetts General Hospital | NCT02160288 | Effects of Type A Botulinum Toxin in Obstructed Defecation Syndrome: a Phase II Randomized, Parallel-Group, Triple-Blind, Placebo-Controlled Trial [pACT] | 2019-06-11 | |
reported-late | Massachusetts General Hospital | NCT01936480 | Genetics of QT Response to Moxifloxacin [pACT] | 2019-06-19 | 650 |
reported-late | Massachusetts General Hospital | NCT01531959 | Midodrine for the Treatment of Refractory Hypotension in Patients Otherwise Ready for Discharge From the ICU [pACT] | 2019-06-30 | 56 |
reported-late | Massachusetts General Hospital | NCT02505269 | Brentuximab Vedotin Plus AD in Non-bulky Limited Stage Hodgkin Lymphoma [pACT] | 2019-06-30 | 41 |
reported | Massachusetts General Hospital | NCT03840278 | The Bihormonal iLet Bionic Pancreas Feasibility Study | 2019-07-03 | |
reported-late | Massachusetts General Hospital | NCT03262116 | Individualizing Automated Closed Loop Glucose Control Through Pharmacokinetic Profiling in an Insulin-Only Bionic Pancreas | 2019-07-23 | 581 |
reported | Massachusetts General Hospital | NCT02955147 | Open Label Study to Test the Safety and Efficacy of Ustekinumab in Patients With Giant Cell Arteritis [pACT] | 2019-07-25 | |
reported-late | Massachusetts General Hospital | NCT02323295 | Pilot Study of the Effect of High Doses of Radiation on Bone Metabolism and Structure in Patients Treated With Adjuvant Radiotherapy and Surgery for Sacral Tumors [pACT] | 2019-07-31 | 329 |
reported-late | Massachusetts General Hospital | NCT03256136 | A Phase II Study of Nivolumab in Combination With Carboplatin and Pemetrexed, or Nivolumab in Combination With Ipilimumab, in Patients With Advanced, EGFR-mutant or ALK-rearranged, Non-Small Cell Lung Cancer | 2019-08-19 | 34 |
reported | Massachusetts General Hospital | NCT02945150 | A Proof of Concept Study of Preemptive Treatment With Grazoprevir and Elbasvir for Donor HCV Positive to Recipient HCV Negative Kidney Transplant | 2019-08-20 | |
reported-late | Massachusetts General Hospital | NCT03118466 | Phase 2 Study of Mitoxantrone, Etoposide, and Cytarabine (MEC) Plus Lenalidomide for the Treatment of Adult Patients With Relapsed or Refractory Acute Myeloid Leukemia | 2019-08-29 | 137 |
overdue | Massachusetts General Hospital | NCT02817061 | Effectiveness of Light for Enhancement of Cognition by Transcranial Repeated Application (ELECTRA): a Placebo-Controlled Study of Efficacy, Tolerability and Acceptability in Healthy Adult Volunteers | 2019-09-01 | 1256 |
overdue | Massachusetts General Hospital | NCT03904602 | EdemaWear to Reduce Edema in Hospitalized Patients With Chronic Venous Insufficiency: A Pilot Study | 2019-09-15 | 1242 |
reported-late | Massachusetts General Hospital | NCT03594045 | A Phase II Study to Evaluate the Efficacy and Safety of Apixaban in the Treatment of Heparin Induced Thrombocytopenia (HIT) | 2019-10-30 | 30 |
reported | Massachusetts General Hospital | NCT02346526 | A Single-arm Open Label Biomarker Study of Standard-of-care Radium-223 Chloride for Metastatic Castration-resistant Prostate Cancer [pACT] | 2019-10-31 |